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1. 发明申请

US20090259194A1 Keyed Safety Cap and Receptacle for Two Piece Injection Device 审中-公开
标题翻译：双片注射装置的安全帽和插座
公开(公告)号：US20090259194A1
公开(公告)日：2009-10-15
申请号：US12101595
申请日：2008-04-11
申请人： Raffi Pinedjian , Robert J. Sanchez, JR. , Jeffrey Chun
发明人： Raffi Pinedjian , Robert J. Sanchez, JR. , Jeffrey Chun
IPC分类号： A61M5/32
CPC分类号： A61M5/20 , A61F9/0008 , A61M5/002 , A61M5/24 , A61M5/3202 , A61M5/3213 , A61M5/44 , A61M2005/2073 , A61M2205/36 , A61M2205/3606 , A61M2205/3653 , A61M2205/50
摘要： A keyed safety system for an injection device that has a safety cap and a receptacle. The safety cap has a generally hollow body for receiving the needle end of an injection device. An orientation mechanism is disposed on the outer surface of the safety cap, a retention mechanism is disposed on the outer surface of the safety cap, and a shroud extends from the safety cap. The receptacle has a cavity for receiving the safety cap. A complimentary orientation mechanism is disposed on a surface of the cavity, and a complimentary retention mechanism is disposed on the surface of the cavity. The orientation mechanism on the safety cap is configured to engage the complimentary orientation mechanism on the cavity so that the safety cap fits into the cavity in a single orientation. The retention mechanism on the safety cap is configured to engage the complimentary retention mechanism on the cavity so that the safety cap is prevented from rotating in the cavity.
摘要翻译：具有安全帽和插座的注射装置的带键安全系统。安全帽具有用于接收注射装置的针端的大致中空体。定位机构设置在安全帽的外表面上，保持机构设置在安全帽的外表面上，护罩从安全帽延伸。容器具有用于接收安全帽的空腔。在空腔的表面上设置有互补的取向机构，并且在空腔的表面上设置有互补的保持机构。安全帽上的取向机构构造成与空腔上的互补取向机构接合，使得安全帽以单个取向装配到空腔中。安全帽上的保持机构构造成与空腔上的互补保持机构接合，从而防止安全帽在空腔中旋转。

2. 发明申请

US20090036868A1 Spring Driven Ophthalmic Injection Device with Safety Actuator Lockout Feature 有权
标题翻译：具有安全执行器锁定功能的弹簧驱动眼科注射装置
公开(公告)号：US20090036868A1
公开(公告)日：2009-02-05
申请号：US12025868
申请日：2008-02-05
申请人： Raffi Pinedjian , Robert J. Sanchez, JR.
发明人： Raffi Pinedjian , Robert J. Sanchez, JR.
IPC分类号： A61M5/36
CPC分类号： A61F9/0017 , A61M5/2033 , A61M5/24 , A61M5/31511 , A61M2005/2073
摘要： An ophthalmic injection device includes a dispensing chamber housing with an inner surface that partially defines a dispensing chamber for holding a substance, a plunger fluidly sealed to the interior surface of the dispensing chamber housing, and a needle fluidly coupled to the dispensing chamber. A temperature control device partially surrounds the dispensing chamber housing and alters a temperature of the substance. A piston is coupled to the plunger at one end and to a spring at the other end. The spring provides a force to drive the piston and the plunger. An actuator is coupled to the lockout bar with which a button is configured to interface. The actuator moves the lockout bar when the substance reaches a temperature, thereby allowing the button to be activated so that the spring provides the force to drive the plunger. An incorporated stop whose measurements may vary allow the expelled dosage to vary accordingly.
摘要翻译：眼科注射装置包括具有部分地限定用于保持物质的分配室的内表面的分配腔室壳体，以及流体地密封到分配腔室壳体的内表面的柱塞，以及流体地联接到分配室的针头。温度控制装置部分地围绕分配腔室并改变物质的温度。活塞在一端连接到柱塞，另一端连接到弹簧。弹簧提供驱动活塞和柱塞的力。致动器联接到锁定杆，通过该锁定杆将按钮配置成与其接合。当物质达到温度时，致动器移动锁定杆，从而允许按钮被激活，使得弹簧提供力来驱动柱塞。其测量值可能变化的合并停止点可以相应地改变排出剂量。

3. 发明申请

US20120022505A1 Closed loop glaucoma drug delivery system 审中-公开
标题翻译：闭环青光眼药物输送系统
公开(公告)号：US20120022505A1
公开(公告)日：2012-01-26
申请号：US13109155
申请日：2011-05-17
申请人： Bruno Dacquay , Robert J. Sanchez, JR. , Matthew J.A. Rickard
发明人： Bruno Dacquay , Robert J. Sanchez, JR. , Matthew J.A. Rickard
IPC分类号： A61M5/00
CPC分类号： A61M5/1723 , A61B3/16 , A61M5/14276 , A61M2005/1726 , A61M2205/3523 , A61M2205/3569 , A61M2205/52 , A61M2205/8243 , A61M2210/0612
摘要： A device implantable into an eye of a patient for treatment of glaucoma. The device has an implantable sensor configured to measure at least one characteristic of the eye. The implantable sensor is sized for implantation into the eye. The device also has an implantable processor coupled to the sensor and configured to receive the measurement of the at least one characteristic of the eye and generate a signal based on the received measurement. Additionally, the device has an implantable actuator coupled to the processor and operable to release a dosage of a therapeutic agent into the eye in response to the signal from the implantable processor.
摘要翻译：可植入患者眼睛的用于治疗青光眼的装置。该装置具有被配置为测量眼睛的至少一种特征的可植入传感器。该植入式传感器的尺寸适于植入眼睛。该装置还具有耦合到传感器的可植入处理器，并且被配置为接收眼睛的至少一个特性的测量并且基于所接收的测量产生信号。另外，该装置具有耦合到处理器的可植入致动器，并且可操作以响应于来自可植入处理器的信号将治疗剂的剂量释放到眼睛中。

4. 发明申请

US20140046439A1 IMPLANTABLE MEMS DEVICE AND METHOD 有权
标题翻译：可植入的MEMS器件及方法
公开(公告)号：US20140046439A1
公开(公告)日：2014-02-13
申请号：US13584435
申请日：2012-08-13
申请人： Cesario P. Dos Santos , Nicholas M. Gunn , Robert J. Sanchez, JR. , Leslie A. Field , Chen Ning
发明人： Cesario P. Dos Santos , Nicholas M. Gunn , Robert J. Sanchez, JR. , Leslie A. Field , Chen Ning
IPC分类号： A61F2/16 , B32B37/14 , B32B38/10 , B32B37/12
CPC分类号： A61F9/00781 , A61B3/16 , A61B2562/028 , A61F2210/0076
摘要： An implantable MEMS package for the treatment of an ocular condition is provided. The MEMS package includes an outer portion; an active portion attached to the outer portion, the active portion including a fluid regulating element having a moving element; and a fluidic channel at an interface of the outer portion and the active portion. The fluidic channel is formed in at least one of the outer and active portions and permits fluid communication from the MEMS package to the fluid regulating element. A method for forming a MEMS package as above is also provided. An ocular implant for treating glaucoma including an inlet tube for receiving aqueous humor; a MEMS package as above, coupled to the inlet tube; a control system to control the MEMS package; and an outlet tube for draining aqueous humor at a drainage location, is provided.
摘要翻译：提供了一种用于治疗眼睛病症的植入式MEMS封装。 MEMS封装包括外部部分; 活动部分附接到外部部分，活动部分包括具有移动元件的流体调节元件; 以及在外部部分和活动部分的界面处的流体通道。流体通道形成在外部和活动部分中的至少一个中，并且允许从MEMS封装到流体调节元件的流体连通。还提供了如上形成MEMS封装的方法。一种用于治疗青光眼的眼部植入物，包括用于接收房水的入口管; 如上所述的MEMS封装，耦合到入口管; 控制系统来控制MEMS封装; 并且提供用于在排水位置排出房水的出口管。

5. 发明申请

US20110022117A1 Cytokine Production Via Electrical Stimulation to Treat Glaucoma 审中-公开
标题翻译：通过电刺激治疗青光眼的细胞因子生产
公开(公告)号：US20110022117A1
公开(公告)日：2011-01-27
申请号：US12507232
申请日：2009-07-22
申请人： Casey Lind , Robert J. Sanchez, JR.
发明人： Casey Lind , Robert J. Sanchez, JR.
IPC分类号： A61F9/00 , A61N1/36
CPC分类号： A61N1/36046 , A61F9/00781 , A61N1/0543
摘要： The present invention is a method of treating glaucoma by electrically stimulating the ciliary muscle to produce shear stress on the trabecular meshwork sufficient for cytokine production. A device for electrically stimulating the ciliary muscle includes a pair of electrodes configured to provide a voltage to the ciliary muscle. The electrodes are coupled to a voltage source. A controller operates to apply the voltage to the ciliary muscle.
摘要翻译：本发明是通过电刺激睫状肌以在足以产生细胞因子的小梁网上产生剪切应力来治疗青光眼的方法。用于电刺激睫状肌的装置包括配置成向睫状肌提供电压的一对电极。电极耦合到电压源。控制器操作以将电压施加到睫状肌上。

6. 发明申请

US20090118680A1 Automatic gas filling consumable 审中-公开
标题翻译：自动充气消耗品
公开(公告)号：US20090118680A1
公开(公告)日：2009-05-07
申请号：US11935171
申请日：2007-11-05
申请人： Peter Goldbrunner , Robert J. Sanchez, JR. , Mark A. Hopkins
发明人： Peter Goldbrunner , Robert J. Sanchez, JR. , Mark A. Hopkins
IPC分类号： A61M5/315
CPC分类号： A61M5/2053 , A61M5/3135 , A61M5/31511 , A61M5/31515 , A61M2005/2006 , A61M2005/3128
摘要： An improved consumable for use in a fluid/gas exchange in vitreoretinal surgery. The consumable includes a syringe having a barrel with a first opening for receiving a retinal tamponading gas, a stopper slidably disposed within and fluidly sealed to the barrel, a plug assembly, and a plunger. The stopper has a relief valve for venting air and retinal tamponading gas to atmosphere via a hollow bore in the plunger.
摘要翻译：用于玻璃体视网膜手术中的流体/气体交换的改进的消耗品。消耗品包括具有筒体的注射器，该桶具有用于接收视网膜保压气体的第一开口，可滑动地设置在筒体内并且流体密封到筒体上的塞子，塞子组件和柱塞。止动器具有安全阀，用于通过柱塞中的中空孔将空气和视网膜保压气体排放到大气中。

7. 发明申请

US20130317412A1 Flow Control For Treating A Medical Condition 审中-公开
标题翻译：治疗病情的流量控制
公开(公告)号：US20130317412A1
公开(公告)日：2013-11-28
申请号：US13478145
申请日：2012-05-23
申请人： Bruno Dacquay , Cesario P. Dos Santos , Casey J. Lind , Robert J. Sanchez, JR. , Mathew J.A. Rickard
发明人： Bruno Dacquay , Cesario P. Dos Santos , Casey J. Lind , Robert J. Sanchez, JR. , Mathew J.A. Rickard
IPC分类号： A61F9/00
CPC分类号： A61F9/00781 , A61B5/0031 , A61B5/03
摘要： An apparatus for treatment of a medical condition of a patient to provide drainage from a region of a patient to a drainage location includes a memory having a plurality of different selectable treatment algorithms stored therein for treating a medical condition, and may include a processor associated with the memory and configured to execute one of the different treatment algorithms. It also may include a flow system controllable by the processor to regulate drainage of fluid from a body portion having a medical condition, the flow system being controllable according to a selected algorithm of said different selectable treatment algorithms. In one aspect, the apparatus further comprises an implantable medical device for treating an ocular condition, and the processor is carried on the implantable medical device.
摘要翻译：一种用于治疗患者的医疗状况以提供从患者区域到排水位置的排泄的装置包括：存储器，其存储有用于治疗医疗状况的多种不同的可选择的治疗算法，并且可以包括与存储器并且被配置为执行不同处理算法之一。它还可以包括可由处理器控制的流动系统，以调节来自具有医疗状况的身体部分的流体的排出，所述流动系统可根据所述不同的可选择治疗算法的所选择的算法来控制。在一个方面，所述装置还包括用于治疗眼睛状况的可植入医疗装置，并且所述处理器承载在所述可植入医疗装置上。

8. 发明申请

US20130211313A1 Corrugated Membrane Actuators 有权
标题翻译：波纹膜驱动器
公开(公告)号：US20130211313A1
公开(公告)日：2013-08-15
申请号：US13396011
申请日：2012-02-14
申请人： Cesario P. Dos Santos , Robert J. Sanchez, JR. , Leslie A. Field
发明人： Cesario P. Dos Santos , Robert J. Sanchez, JR. , Leslie A. Field
IPC分类号： A61F9/00
CPC分类号： A61F9/00781 , A61M2039/2433
摘要： An IOP control valve is disclosed. The IOP control valve comprises a corrugated membrane and a housing including a fluid inlet and a fluid outlet. The corrugated membrane is anchored within the housing to form a reference chamber on a first side of the corrugated membrane and a fluid flow channel on a second opposing side of the membrane. The reference chamber has a reference chamber pressure representative of atmospheric pressure. The fluid flow channel can selectively increase and decrease in size to permit fluid to flow from the fluid inlet to the fluid outlet. The corrugated membrane is configured to affect flow through the fluid flow channel from the fluid inlet to the fluid outlet by deflecting in response to pressure differentials of the reference chamber pressure and the fluid flow channel pressure acting on the opposing sides of the corrugated membrane.
摘要翻译：公开了一种IOP控制阀。 IOP控制阀包括波纹膜和包括流体入口和流体出口的壳体。波纹膜被锚固在壳体内以在波纹膜的第一侧上形成参考室，并且在膜的第二相对侧上形成流体流动通道。参考室具有代表大气压力的参考室压力。流体流动通道可以选择性地增加和减小尺寸，以允许流体从流体入口流到流体出口。波纹膜被配置为响应于参考室压力和作用在波纹膜的相对侧上的流体流动通道压力的压力而通过偏转而影响通过流体流动通道从流体入口到流体出口的流动。

9. 发明申请

US20110034864A1 PHACOEMULSIFICATION HANDPIECE PRESSURE BOOSTER 有权
标题翻译： PHACOEMULSIFICATION HANDPIECE压力增压器
公开(公告)号：US20110034864A1
公开(公告)日：2011-02-10
申请号：US12536539
申请日：2009-08-06
申请人： Bruno Dacquay , Robert J. Sanchez, JR.
发明人： Bruno Dacquay , Robert J. Sanchez, JR.
IPC分类号： A61F9/007 , A61M1/00
CPC分类号： A61M1/0031 , A61M1/0064 , A61M3/0283 , A61M2210/0612
摘要： In various embodiments, a handpiece may include an irrigation line coupled to an adjacent line reservoir with a piston configured to move within the adjacent line reservoir to increase an irrigation pressure in the irrigation line near a surgical site. In some embodiments, a sensor may be used to detect an occlusion break in the aspiration line and information from the sensor may result in signaling an actuator to move the piston in response to the occlusion break detection to compensate for a vacuum pressure drop associated with the occlusion break. The handpiece may further include a purge bypass line between the irrigation line and the adjacent line reservoir to allow flow from the irrigation line to travel through the adjacent line reservoir to purge the adjacent line reservoir.
摘要翻译：在各种实施例中，手持件可以包括连接到相邻的线容器的冲洗管线，其中活塞构造成在相邻管线容器内移动以增加在外科手术部位附近的灌溉管线中的冲洗压力。在一些实施例中，可以使用传感器来检测抽吸管线中的堵塞断裂，并且来自传感器的信息可以导致致动器响应于闭塞断裂检测而使活塞移动以补偿与...相关联的真空压降闭塞断裂所述手持件还可以包括在所述冲洗管线和所述相邻的管线容器之间的净化旁通管线，以允许从所述灌溉管线流出以通过所述相邻的管线储存器以净化所述相邻的管路储存器。

10. 发明申请

US20100030157A1 Drug Retention Cap 审中-公开
标题翻译：药物保留上限
公开(公告)号：US20100030157A1
公开(公告)日：2010-02-04
申请号：US12364004
申请日：2009-02-02
申请人： Cesario Dos Santos , Robert J. Sanchez, JR.
发明人： Cesario Dos Santos , Robert J. Sanchez, JR.
IPC分类号： A61M5/31 , A61B19/02
CPC分类号： A61M5/3202 , A61M2005/311
摘要： A drug retention cap has a cap section and a drug retention pin. The cap section has a generally dome-shaped top end and a cylindrical portion extending downward from the generally dome-shaped top end. The top end of the cap section is closed, and the bottom end is open. The open bottom end is configured to receive a needle of a drug delivery device. The drug retention pin extends from near the apex of the dome-shaped top end downward toward the open bottom end. The drug retention pin is configured to fit inside a hollow needle.
摘要翻译：药物保持帽具有帽部分和药物保持针。盖部分具有大致圆顶形的顶端和从大致圆顶形的顶端向下延伸的圆柱形部分。盖部分的顶端封闭，底端打开。打开的底端构造成接收药物递送装置的针。药物保持销从圆顶状顶端的顶点附近向下朝向开放的底端延伸。药物保持销被配置成装配在中空针内。

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