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1. 发明授权

US08876751B2 Phacoemulsification handpiece pressure booster 有权
标题翻译：超声乳化手机加压器
公开(公告)号：US08876751B2
公开(公告)日：2014-11-04
申请号：US12536539
申请日：2009-08-06
申请人： Bruno Dacquay , Robert J. Sanchez, Jr.
发明人： Bruno Dacquay , Robert J. Sanchez, Jr.
IPC分类号： A61M1/00
CPC分类号： A61M1/0031 , A61M1/0064 , A61M3/0283 , A61M2210/0612
摘要： In various embodiments, a handpiece may include an irrigation line coupled to an adjacent line reservoir with a piston configured to move within the adjacent line reservoir to increase an irrigation pressure in the irrigation line near a surgical site. In some embodiments, a sensor may be used to detect an occlusion break in the aspiration line and information from the sensor may result in signaling an actuator to move the piston in response to the occlusion break detection to compensate for a vacuum pressure drop associated with the occlusion break. The handpiece may further include a purge bypass line between the irrigation line and the adjacent line reservoir to allow flow from the irrigation line to travel through the adjacent line reservoir to purge the adjacent line reservoir.
摘要翻译：在各种实施例中，手持件可以包括连接到相邻的线容器的冲洗管线，其中活塞构造成在相邻管线容器内移动以增加在外科手术部位附近的灌溉管线中的冲洗压力。在一些实施例中，可以使用传感器来检测抽吸管线中的堵塞断裂，并且来自传感器的信息可以导致致动器响应于闭塞断裂检测而使活塞移动以补偿与...相关联的真空压降闭塞断裂所述手持件还可以包括在所述冲洗管线和所述相邻的管线容器之间的净化旁通管线，以允许从所述灌溉管线流出以通过所述相邻的管线储存器以净化所述相邻的管路储存器。

2. 发明申请

US20130317412A1 Flow Control For Treating A Medical Condition 审中-公开
标题翻译：治疗病情的流量控制
公开(公告)号：US20130317412A1
公开(公告)日：2013-11-28
申请号：US13478145
申请日：2012-05-23
申请人： Bruno Dacquay , Cesario P. Dos Santos , Casey J. Lind , Robert J. Sanchez, JR. , Mathew J.A. Rickard
发明人： Bruno Dacquay , Cesario P. Dos Santos , Casey J. Lind , Robert J. Sanchez, JR. , Mathew J.A. Rickard
IPC分类号： A61F9/00
CPC分类号： A61F9/00781 , A61B5/0031 , A61B5/03
摘要： An apparatus for treatment of a medical condition of a patient to provide drainage from a region of a patient to a drainage location includes a memory having a plurality of different selectable treatment algorithms stored therein for treating a medical condition, and may include a processor associated with the memory and configured to execute one of the different treatment algorithms. It also may include a flow system controllable by the processor to regulate drainage of fluid from a body portion having a medical condition, the flow system being controllable according to a selected algorithm of said different selectable treatment algorithms. In one aspect, the apparatus further comprises an implantable medical device for treating an ocular condition, and the processor is carried on the implantable medical device.
摘要翻译：一种用于治疗患者的医疗状况以提供从患者区域到排水位置的排泄的装置包括：存储器，其存储有用于治疗医疗状况的多种不同的可选择的治疗算法，并且可以包括与存储器并且被配置为执行不同处理算法之一。它还可以包括可由处理器控制的流动系统，以调节来自具有医疗状况的身体部分的流体的排出，所述流动系统可根据所述不同的可选择治疗算法的所选择的算法来控制。在一个方面，所述装置还包括用于治疗眼睛状况的可植入医疗装置，并且所述处理器承载在所述可植入医疗装置上。

3. 发明申请

US20110034864A1 PHACOEMULSIFICATION HANDPIECE PRESSURE BOOSTER 有权
标题翻译： PHACOEMULSIFICATION HANDPIECE压力增压器
公开(公告)号：US20110034864A1
公开(公告)日：2011-02-10
申请号：US12536539
申请日：2009-08-06
申请人： Bruno Dacquay , Robert J. Sanchez, JR.
发明人： Bruno Dacquay , Robert J. Sanchez, JR.
IPC分类号： A61F9/007 , A61M1/00
CPC分类号： A61M1/0031 , A61M1/0064 , A61M3/0283 , A61M2210/0612
摘要： In various embodiments, a handpiece may include an irrigation line coupled to an adjacent line reservoir with a piston configured to move within the adjacent line reservoir to increase an irrigation pressure in the irrigation line near a surgical site. In some embodiments, a sensor may be used to detect an occlusion break in the aspiration line and information from the sensor may result in signaling an actuator to move the piston in response to the occlusion break detection to compensate for a vacuum pressure drop associated with the occlusion break. The handpiece may further include a purge bypass line between the irrigation line and the adjacent line reservoir to allow flow from the irrigation line to travel through the adjacent line reservoir to purge the adjacent line reservoir.
摘要翻译：在各种实施例中，手持件可以包括连接到相邻的线容器的冲洗管线，其中活塞构造成在相邻管线容器内移动以增加在外科手术部位附近的灌溉管线中的冲洗压力。在一些实施例中，可以使用传感器来检测抽吸管线中的堵塞断裂，并且来自传感器的信息可以导致致动器响应于闭塞断裂检测而使活塞移动以补偿与...相关联的真空压降闭塞断裂所述手持件还可以包括在所述冲洗管线和所述相邻的管线容器之间的净化旁通管线，以允许从所述灌溉管线流出以通过所述相邻的管线储存器以净化所述相邻的管路储存器。

4. 发明申请

US20120022505A1 Closed loop glaucoma drug delivery system 审中-公开
标题翻译：闭环青光眼药物输送系统
公开(公告)号：US20120022505A1
公开(公告)日：2012-01-26
申请号：US13109155
申请日：2011-05-17
申请人： Bruno Dacquay , Robert J. Sanchez, JR. , Matthew J.A. Rickard
发明人： Bruno Dacquay , Robert J. Sanchez, JR. , Matthew J.A. Rickard
IPC分类号： A61M5/00
CPC分类号： A61M5/1723 , A61B3/16 , A61M5/14276 , A61M2005/1726 , A61M2205/3523 , A61M2205/3569 , A61M2205/52 , A61M2205/8243 , A61M2210/0612
摘要： A device implantable into an eye of a patient for treatment of glaucoma. The device has an implantable sensor configured to measure at least one characteristic of the eye. The implantable sensor is sized for implantation into the eye. The device also has an implantable processor coupled to the sensor and configured to receive the measurement of the at least one characteristic of the eye and generate a signal based on the received measurement. Additionally, the device has an implantable actuator coupled to the processor and operable to release a dosage of a therapeutic agent into the eye in response to the signal from the implantable processor.
摘要翻译：可植入患者眼睛的用于治疗青光眼的装置。该装置具有被配置为测量眼睛的至少一种特征的可植入传感器。该植入式传感器的尺寸适于植入眼睛。该装置还具有耦合到传感器的可植入处理器，并且被配置为接收眼睛的至少一个特性的测量并且基于所接收的测量产生信号。另外，该装置具有耦合到处理器的可植入致动器，并且可操作以响应于来自可植入处理器的信号将治疗剂的剂量释放到眼睛中。

5. 发明授权

US09022970B2 Ophthalmic injection device including dosage control device 有权
标题翻译：眼科注射装置包括剂量控制装置
公开(公告)号：US09022970B2
公开(公告)日：2015-05-05
申请号：US12444044
申请日：2007-10-09
申请人： Bruno Dacquay , Casey Lind , Cesario Dos Santos , Robert J Sanchez, Jr.
发明人： Bruno Dacquay , Casey Lind , Cesario Dos Santos , Robert J Sanchez, Jr.
IPC分类号： A61M5/315 , A61F9/00 , A61M5/142 , A61M5/20
CPC分类号： A61F9/0017 , A61M5/14224 , A61M5/20 , A61M5/31525 , A61M5/31546 , A61M2205/0244 , A61M2205/3368 , A61M2205/3606 , A61M2205/3653 , A61M2205/6018 , A61M2210/0612
摘要： An injection device includes a dispensing chamber, a plunger, a controller, a temperature control device, and a memory device. The dispensing chamber has an inner surface and an outer surface. The inner surface defines a cavity for receiving a quantity of a substance. The plunger is engaged with the inner surface of the dispensing chamber, is capable of sliding in the cavity of the dispensing chamber, and is fluidly sealed to the inner surface of the dispensing chamber. The controller controls the operation of the injection device. The temperature control device at least partially surrounds the dispensing chamber. The memory device has a parameter stored on it. The controller uses the parameter from the memory device to operate the injection device.
摘要翻译：注射装置包括分配室，柱塞，控制器，温度控制装置和存储装置。分配室具有内表面和外表面。内表面限定用于接收一定量的物质的空腔。柱塞与分配室的内表面接合，能够在分配室的空腔中滑动，并且流体地密封到分配室的内表面。控制器控制注射装置的操作。温度控制装置至少部分地围绕分配室。存储器件具有存储在其上的参数。控制器使用来自存储器装置的参数来操作注射装置。

6. 发明申请

US20120022506A1 Drug delivery device with active iris 审中-公开
标题翻译：带有活动虹膜的药物输送装置
公开(公告)号：US20120022506A1
公开(公告)日：2012-01-26
申请号：US13113800
申请日：2011-05-23
申请人： Matthew J.A. Rickard , Robert J. Sanchez, JR. , Bruno Dacquay
发明人： Matthew J.A. Rickard , Robert J. Sanchez, JR. , Bruno Dacquay
IPC分类号： A61F9/00
CPC分类号： A61F9/00781 , A61B2562/0247 , A61F9/0017 , A61F2250/0068
摘要： A device implantable into an eye of a patient for treatment of glaucoma. The device has an implantable dispenser. The dispenser includes an implantable reservoir configured to store a therapeutic agent. Additionally, the dispenser includes an implantable reservoir sensor configured to measure a pressure within the reservoir. The device also has an implantable processor coupled to the implantable reservoir sensor and configured to receive the measurement of the pressure within the reservoir and determine a dosage of therapeutic agent based on the measurement of the pressure within the reservoir. Furthermore, the implantable dispenser is configured to release the dosage of the therapeutic agent at a selectively variable rate from the implantable reservoir into the eye.
摘要翻译：可植入患者眼睛的用于治疗青光眼的装置。该装置具有可植入分配器。分配器包括构造成存储治疗剂的可植入储存器。另外，分配器包括构造成测量储存器内的压力的可植入储存器传感器。该装置还具有联接到可植入储存器传感器的可植入处理器，并且被配置为接收储存器内的压力的测量，并且基于储存器内的压力的测量来确定治疗剂的剂量。此外，可植入分配器被配置为以可选择的可变速率将可治疗剂的剂量从可植入储存器释放到眼睛中。

7. 发明申请

US20100152676A1 Drug Loading Through Plunger 审中-公开
标题翻译：药物通过柱塞装载
公开(公告)号：US20100152676A1
公开(公告)日：2010-06-17
申请号：US12635334
申请日：2009-12-10
申请人： Don A. Clements , Julie A. Clifford , Bruno Dacquay , Mark T. DuPriest , Robert Rodstrom , Robert J. Sanchez, JR. , Pardeep K. Sethi
发明人： Don A. Clements , Julie A. Clifford , Bruno Dacquay , Mark T. DuPriest , Robert Rodstrom , Robert J. Sanchez, JR. , Pardeep K. Sethi
IPC分类号： A61M5/315 , B65B3/04
CPC分类号： A61M5/20 , A61F9/0017 , A61M5/1782 , A61M5/24 , A61M5/31511 , A61M5/31515 , A61M5/50 , A61M2205/3653 , B65B3/003
摘要： A drug loading apparatus includes a plunger with a through hole or slit valve located in the top face of the plunger. A dispensing chamber housing located in a drug delivery device is configured to receive the plunger so that a dispensing chamber is formed when the plunger is located in the dispensing chamber housing. The drug can then be loaded into the dispensing chamber through the plunger, and a piston with an end configured to seal the through hole or engage the plunger with the slit valve can then be inserted.
摘要翻译：药物装载装置包括具有位于柱塞的顶面中的通孔或狭缝阀的柱塞。位于药物输送装置中的分配腔室构造成容纳柱塞，使得当柱塞位于分配腔室壳体中时形成分配室。然后可以通过柱塞将药物装载到分配室中，然后可以插入具有构造成密封通孔或将柱塞与狭缝阀接合的端部的活塞。

8. 发明申请

US20100030136A1 Ophthalmic Injection Device Including Dosage Control Device 有权
标题翻译：包括剂量控制装置的眼科注射装置
公开(公告)号：US20100030136A1
公开(公告)日：2010-02-04
申请号：US12444044
申请日：2007-10-09
申请人： Bruno Dacquay , Casey Lind , Cesario Dos Santos , Robert J. Sanchez, JR.
发明人： Bruno Dacquay , Casey Lind , Cesario Dos Santos , Robert J. Sanchez, JR.
IPC分类号： A61M5/50 , A61M5/31
CPC分类号： A61F9/0017 , A61M5/14224 , A61M5/20 , A61M5/31525 , A61M5/31546 , A61M2205/0244 , A61M2205/3368 , A61M2205/3606 , A61M2205/3653 , A61M2205/6018 , A61M2210/0612
摘要： An injection device includes a dispensing chamber, a plunger, a controller, a temperature control device, and a memory device. The dispensing chamber has an inner surface and an outer surface. The inner surface defines a cavity for receiving a quantity of a substance. The plunger is engaged with the inner surface of the dispensing chamber, is capable of sliding in the cavity of the dispensing chamber, and is fluidly sealed to the inner surface of the dispensing chamber. The controller controls the operation of the injection device. The temperature control device at least partially surrounds the dispensing chamber. The memory device has a parameter stored on it. The controller uses the parameter from the memory device to operate the injection device.
摘要翻译：注射装置包括分配室，柱塞，控制器，温度控制装置和存储装置。分配室具有内表面和外表面。内表面限定用于接收一定量的物质的空腔。柱塞与分配室的内表面接合，能够在分配室的空腔中滑动，并且流体地密封到分配室的内表面。控制器控制注射装置的操作。温度控制装置至少部分地围绕分配室。存储器件具有存储在其上的参数。控制器使用来自存储器装置的参数来操作注射装置。

9. 发明申请

US20090093789A1 Method of Delivering A Rate And Temperature - Dependent Substance Into The Eye 审中-公开
标题翻译：提供速率和温度依赖物质进入眼睛的方法
公开(公告)号：US20090093789A1
公开(公告)日：2009-04-09
申请号：US12243729
申请日：2008-10-01
申请人： Bruno Dacquay , Cesario Pereira Dos Santos , Casey Jean Lind , Robert J. Sanchez, JR.
发明人： Bruno Dacquay , Cesario Pereira Dos Santos , Casey Jean Lind , Robert J. Sanchez, JR.
IPC分类号： A61M5/44
CPC分类号： A61F9/0017 , A61M5/14566 , A61M5/445 , A61M2005/14268 , A61M2205/3606 , A61M2205/3653
摘要： A method of injecting a mixture into an eye includes: providing the mixture in a dispensing chamber with an air gap located between the mixture and an interior surface of a dispensing chamber housing, when the mixture and dispensing chamber housing are near room temperature; bringing the dispensing chamber housing and mixture to a temperature range, other than near room temperature, at which the mixture expands and is in a more liquid state; maintaining air in a needle after the mixture expands and prior to an injection; selecting a drug release rate; and injecting the mixture so as to form a shape with a surface area that results in the selected drug release rate.
摘要翻译：将混合物注入到眼睛中的方法包括：当混合物和分配室壳体接近室温时，将混合物提供在分配腔室中，该混合物位于混合物和分配室壳体的内表面之间的气隙; 使分配室壳体和混合物处于不同于室温附近的温度范围，混合物膨胀并处于更液态的温度范围; 在混合物膨胀并且在注射之前，将空气保持在针中; 选择药物释放率; 并注入混合物以形成具有导致所选择的药物释放速率的表面积的形状。

10. 发明授权

US07871399B2 Disposable ophthalmic injection device 有权
标题翻译：一次性眼科注射装置
公开(公告)号：US07871399B2
公开(公告)日：2011-01-18
申请号：US11832243
申请日：2007-08-01
申请人： Bruno Dacquay , Cesario Dos Santos , James Foster , Robert Sanchez
发明人： Bruno Dacquay , Cesario Dos Santos , James Foster , Robert Sanchez
IPC分类号： A61F7/00
CPC分类号： A61F9/0017 , A61M1/1058 , A61M5/14244 , A61M5/1452 , A61M5/14546 , A61M5/14566 , A61M5/31511 , A61M5/445 , A61M5/484 , A61M2005/14268 , A61M2205/3331 , A61M2205/3569 , A61M2205/6018 , A61M2205/8206 , A61M2205/8243 , A61M2205/8262 , A61M2209/086 , A61M2210/0612
摘要： A disposable injection device has a dispensing chamber housing, a plunger, a needle, and a temperature control device. The dispensing chamber housing has an inner surface and an outer surface. The inner surface partially defines a dispensing chamber for receiving a quantity of a substance. The plunger is engaged with the inner surface of the dispensing chamber housing, is capable of sliding in the dispensing chamber housing, and is fluidly sealed to the inner surface of the dispensing chamber housing. The plunger has a plunger interface. The needle is fluidly coupled to the dispensing chamber. The temperature control device at least partially surrounds the dispensing chamber housing and alters a temperature of the substance in the dispensing chamber. The substance is injected after the temperature of the substance is altered.
摘要翻译：一次性注射装置具有分配腔室壳体，柱塞，针头和温度控制装置。分配腔室具有内表面和外表面。内表面部分地限定用于接收一定量的物质的分配室。柱塞与分配室壳体的内表面接合，能够在分配室壳体中滑动，并且被流体地密封到分配室壳体的内表面。柱塞具有柱塞接口。针流体地联接到分配室。温度控制装置至少部分地围绕分配室壳体并改变分配室中的物质的温度。物质在物质温度变化后注射。

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