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1. 发明申请

US20070212394A1 Taxane coatings for implantable medical devices 有权
标题翻译：可植入医疗器械的紫杉烷涂层
公开(公告)号：US20070212394A1
公开(公告)日：2007-09-13
申请号：US11715975
申请日：2007-03-08
申请人： Priscilla Reyes , William Moore , Patrick Ruane , Darin Schaeffer
发明人： Priscilla Reyes , William Moore , Patrick Ruane , Darin Schaeffer
IPC分类号： A61K31/337 , A61F2/02
CPC分类号： A61L27/54 , A61F2/91 , A61F2/915 , A61F2002/91533 , A61F2002/91575 , A61F2230/0054 , A61F2250/0067 , A61F2310/0097 , A61K31/337 , A61L29/16 , A61L31/08 , A61L31/16 , A61L2300/416 , A61L2300/606
摘要： This disclosure relates to implantable medical devices coated with a taxane therapeutic agent, such as paclitaxel, in one or more solid form(s) having varying dissolution rates. Particularly preferred coatings comprise amorphous and/or solvated solid forms of taxane therapeutic agents that provide durable coatings that release the taxane over a desired period of time, which can be varied in the absence of a polymer by selecting the type and amount of solid forms of the taxane therapeutic agent in the coating. Other preferred embodiments relate to methods of coating medical devices and methods of treatment. The coatings can provide a sustained release of the taxane therapeutic agent within a body vessel without containing a polymer to achieve the desired rate of paclitaxel elution.
摘要翻译：本公开涉及涂覆有紫杉烷治疗剂（例如紫杉醇）的可植入医疗装置，其具有不同溶解速率的一种或多种固体形式。特别优选的涂层包括紫杉烷治疗剂的无定形和/或溶剂化固体形式，其提供耐久性涂层，其在期望的时间段内释放紫杉烷，其可以在不存在聚合物的情况下变化，通过选择固体形式的类型和量紫杉烷治疗剂在涂层中。其它优选实施方案涉及涂覆医疗装置的方法和治疗方法。涂层可以在体内容器内提供紫杉烷治疗剂的持续释放而不含聚合物以达到期望的紫杉醇洗脱速率。

2. 发明申请

US20070073385A1 Eluting, implantable medical device 审中-公开
标题翻译：洗脱，植入式医疗器械
公开(公告)号：US20070073385A1
公开(公告)日：2007-03-29
申请号：US11523797
申请日：2006-09-18
申请人： Darin Schaeffer , David Grewe , Patrick Ruane
发明人： Darin Schaeffer , David Grewe , Patrick Ruane
IPC分类号： A61F2/90
CPC分类号： A61L31/082 , A61F2/91 , A61F2/915 , A61F2002/30322 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91575 , A61F2230/0054 , A61F2250/0023 , A61F2250/0026 , A61F2250/0068 , A61L31/146 , A61L31/16 , A61L2300/416
摘要： An intraluminal device is provided with a porous structure. The porous structure may be loaded with a bioactive substance to treat surrounding tissues after the intraluminal device has been implanted. The porous structure may be made by depositing a metal film on a foam structure using chemical vapor deposition. Porous structures may also be made by sintering or applying a ceramic layer to the intraluminal device. An intraluminal device is also provided with a ceramic material applied to generally straight portions of the device structure but not to portions adapted to bend. One advantage is that the ceramic material is less likely to fracture since it is applied to regions that experience less strain.
摘要翻译：管腔内装置具有多孔结构。在植入腔内装置之后，多孔结构可装载生物活性物质以治疗周围组织。多孔结构可以通过使用化学气相沉积在金属泡沫结构上沉积金属膜来制造。也可以通过烧结或将陶瓷层施加到腔内装置来制造多孔结构。管腔内装置还设置有施加到装置结构的大致直线部分的陶瓷材料，但是不适于弯曲的部分。一个优点是陶瓷材料不太可能破裂，因为它被应用于经历较小应变的区域。

3. 发明授权

US10022263B2 Sling-based treatment of obstructive sleep apnea 有权
公开(公告)号：US10022263B2
公开(公告)日：2018-07-17
申请号：US13550065
申请日：2012-07-16
申请人： Arun Mohan , Darin Schaeffer , Patrick C. Melder
发明人： Arun Mohan , Darin Schaeffer , Patrick C. Melder
IPC分类号： A61F5/56
摘要： Slings, kits, and methods useful in the treatment of Obstructive Sleep Apnea (OSA) are described. An exemplary sling comprises a main body extending along a lengthwise axis and having first and second opposing ends, first and second opposing sides, and first and second opposing surfaces. Each end defines an end loop that defines a passageway extending through the main body. An exemplary method of treatment comprises creating two openings in the mandible of a patient; creating two longitudinal tunnels in the tongue of the patient; creating a transverse tunnel in the tongue of the patient; advancing a sling through the transverse tunnel; pulling each end of the sling through one of the longitudinal tunnels and through one of the openings in the mandible; pulling the tongue toward the front of the mouth or mandible; and securing the sling to a tissue to support the tongue in a new position.

4. 发明申请

US20150342636A1 Medical Devices Having a Releasable Member and Methods of Using the Same 有权
标题翻译：具有可释放成员的医疗设备及其使用方法
公开(公告)号：US20150342636A1
公开(公告)日：2015-12-03
申请号：US14721618
申请日：2015-05-26
申请人： Darin Schaeffer , Kathryn Hardert , Joshua Haines
发明人： Darin Schaeffer , Kathryn Hardert , Joshua Haines
IPC分类号： A61B17/34 , A61M39/02 , A61M39/10 , A61M25/06
CPC分类号： A61B17/3421 , A61B2017/00477 , A61B2017/345 , A61M25/0662 , A61M39/02 , A61M39/1055
摘要： Medical devices having a releasable member are described. Methods of using medical devices having a releasable member are also described. An example medical device comprises an elongate member, an intermediate member, a sheath, and a cap. Each of the intermediate member, sheath, and cap are releasably disposed on the elongate member.
摘要翻译：描述具有可释放构件的医疗装置。还描述了使用具有可释放构件的医疗装置的方法。示例性的医疗装置包括细长构件，中间构件，护套和帽。中间构件，护套和盖中的每一个可释放地设置在细长构件上。

5. 发明授权

US09089631B2 Irrigation devices adapted to be used with a light source for the identification and treatment of bodily passages 有权
标题翻译：适于与光源一起使用以识别和处理身体通道的灌溉装置
公开(公告)号：US09089631B2
公开(公告)日：2015-07-28
申请号：US13555453
申请日：2012-07-23
申请人： Darin Schaeffer , Patrick C. Melder , Thomas Cherry
发明人： Darin Schaeffer , Patrick C. Melder , Thomas Cherry
IPC分类号： A61B1/12 , A61M3/02 , A61B1/00 , A61B1/015 , A61B1/233
CPC分类号： A61B1/00165 , A61B1/015 , A61B1/233 , A61B90/30 , A61B2090/306 , A61B2217/005 , A61M3/0279 , A61M2205/587 , A61M2210/0681
摘要： Devices and methods of identifying and treating bodily passages, such as sinus cavities, are provided. More particularly, irrigation devices and methods useful in the identification and treatment of bodily passages, such as sinus cavities, are provided. The irrigation devices comprise an elongate tubular member and an optical fiber which assist with the transcutaneous identification and/or treatment of a bodily passage.
摘要翻译：提供了识别和处理身体通道（例如窦腔）的装置和方法。更具体地，提供了用于识别和处理身体通道例如窦腔的灌洗装置和方法。灌溉装置包括细长管状构件和辅助经皮识别和/或处理身体通道的光纤。

6. 发明申请

US20140277066A1 Medical Devices and Methods for Providing Access to a Bodily Passage During Dilation 有权
标题翻译：医疗器械和方法在通气期间提供身体通道
公开(公告)号：US20140277066A1
公开(公告)日：2014-09-18
申请号：US14211374
申请日：2014-03-14
申请人： Darin Schaeffer , Paul Krakovitz , Dan Dalenberg
发明人： Darin Schaeffer , Paul Krakovitz , Dan Dalenberg
IPC分类号： A61M25/10 , A61M16/04
CPC分类号： A61M25/1006 , A61M16/0427 , A61M16/0429 , A61M16/0434 , A61M16/0456 , A61M16/0459 , A61M16/0481 , A61M16/0486 , A61M16/0488 , A61M25/0023 , A61M25/04 , A61M25/0662 , A61M29/02 , A61M2025/0024 , A61M2025/0681 , A61M2025/105 , A61M2025/1052 , A61M2205/32
摘要： Medical devices and methods of treatment are described herein. More particularly, medical devices and methods for providing access to a bodily passage during dilation are described herein. An exemplary medical device comprises an elongate member and a balloon. The elongate member is moveable between a first, non-expanded configuration and a second, expanded configuration.
摘要翻译：本文描述了医疗装置和治疗方法。更具体地，本文描述了用于在扩张期间提供对身体通道的通路的医疗装置和方法。示例性医疗装置包括细长构件和气囊。细长构件可在第一非扩张构型和第二扩张构型之间移动。

7. 发明申请

US20130245662A1 Methods of Providing Access to a Salivary Duct 有权
标题翻译：提供唾液管道的方法
公开(公告)号：US20130245662A1
公开(公告)日：2013-09-19
申请号：US13607861
申请日：2012-09-10
申请人： Darin Schaeffer , Thomas Cherry , Kathryn Evert , Jack Kolenda
发明人： Darin Schaeffer , Thomas Cherry , Kathryn Evert , Jack Kolenda
IPC分类号： A61M29/02
CPC分类号： A61M29/02 , A61M2025/0681
摘要： Methods of treatment are described. More particularly, methods of providing access to a bodily passage, such as a salivary duct, are described herein. For example, methods of providing access to a salivary duct and introducing a sheath and wire guide are described herein. In addition, various methods of treatment are described herein. For example, methods of treating a stone located within a salivary duct are described herein.
摘要翻译：描述了治疗方法。更具体地，本文描述了提供对身体通道（例如唾液管）的通路的方法。例如，本文描述了提供对唾液管的通路和引入鞘和线引导件的方法。此外，本文描述了各种治疗方法。例如，本文描述了治疗位于唾液管内的石块的方法。

8. 发明申请

US20130237967A1 Suction Lithotripsy Apparatus, Method and Kit 有权
标题翻译：吸入碎石装置，方法和试剂盒
公开(公告)号：US20130237967A1
公开(公告)日：2013-09-12
申请号：US13606323
申请日：2012-09-07
申请人： Darin Schaeffer , Nicholas Hardert
发明人： Darin Schaeffer , Nicholas Hardert
IPC分类号： A61B18/26 , A61B17/22
CPC分类号： A61B18/26 , A61B17/22 , A61B17/22012 , A61B17/3421 , A61B17/3462 , A61B2017/22084 , A61B2217/005 , A61B2217/007
摘要： Medical devices, methods and kits useful in the disruption and removal of unwanted materials, such as calculi and other formations, from within body lumens are described. The disclosure describes particular embodiments and methods useful in the lithotriptic removal of stones from the salivary glands.
摘要翻译：描述了可用于破坏和去除体腔内的不想要的材料（例如结石和其它结构）的医疗装置，方法和试剂盒。本公开描述了在从唾液腺中分离去除石块中有用的特定实施方案和方法。

9. 发明申请

US20130056009A1 Sling-Based Treatment of Obstructive Sleep Apnea 有权
标题翻译：阻塞性睡眠呼吸暂停治疗
公开(公告)号：US20130056009A1
公开(公告)日：2013-03-07
申请号：US13550065
申请日：2012-07-16
申请人： Arun Mohan , Darin Schaeffer , Patrick C. Melder
发明人： Arun Mohan , Darin Schaeffer , Patrick C. Melder
IPC分类号： A61F5/56
CPC分类号： A61F5/566
摘要： Slings, kits, and methods useful in the treatment of Obstructive Sleep Apnea (OSA) are described. An exemplary sling comprises a main body extending along a lengthwise axis and having first and second opposing ends, first and second opposing sides, and first and second opposing surfaces. Each end defines an end loop that defines a passageway extending through the main body. An exemplary method of treatment comprises creating two openings in the mandible of a patient; creating two longitudinal tunnels in the tongue of the patient; creating a transverse tunnel in the tongue of the patient; advancing a sling through the transverse tunnel; pulling each end of the sling through one of the longitudinal tunnels and through one of the openings in the mandible; pulling the tongue toward the front of the mouth or mandible; and securing the sling to a tissue to support the tongue in a new position.
摘要翻译：描述了用于治疗阻塞性睡眠呼吸暂停（OSA）的吊索，套件和方法。示例性吊带包括沿着纵向轴线延伸的主体，并且具有第一和第二相对端部，第一和第二相对侧面以及第一和第二相对表面。每个端部限定一个端部环，其限定延伸穿过主体的通道。一种示例性的治疗方法包括在患者的下颌骨中形成两个开口; 在患者的舌头中形成两条纵向隧道; 在患者的舌头中产生横向隧道; 通过横向隧道推进吊索; 通过一个纵向隧道并通过下颌骨中的一个开口牵引吊索的每一端; 将舌头朝向嘴巴或下颌骨的前方拉扯; 并将吊带固定到组织以将舌头支撑在新的位置。

10. 发明申请

US20070179592A1 Branch vessel prosthesis with positional indicator system and method 有权
标题翻译：分支血管假体与位置指示器系统和方法
公开(公告)号：US20070179592A1
公开(公告)日：2007-08-02
申请号：US10984416
申请日：2004-11-08
申请人： Darin Schaeffer
发明人： Darin Schaeffer
IPC分类号： A61F2/06
CPC分类号： A61F2/954 , A61B2017/1107 , A61B2017/1139 , A61F2/064 , A61F2/07 , A61F2/856 , A61F2/88 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2/958 , A61F2002/065 , A61F2002/067 , A61F2002/075 , A61F2002/821 , A61F2002/8483 , A61F2002/8486 , A61F2002/91508 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/91566 , A61F2002/9511 , A61F2210/0076 , A61F2220/0016 , A61F2220/005 , A61F2220/0075 , A61F2220/0083 , A61F2230/005 , A61F2230/0054 , A61F2230/0067 , A61F2230/0078 , A61F2250/0018 , A61F2250/0039 , A61F2250/0097 , A61F2250/0098
摘要： A stent graft system for intraluminal deployment in an aorta and a branch vessel includes an aorta stent graft with a fenestration aligned with a branch vessel and a branch vessel prosthesis with a flaring portion at a proximal end and a tubular portion. When deployed, the flaring portion of the branch vessel prosthesis is retained within the aorta stent graft, and the tubular portion extends through the fenestration and into the branch vessel. The system includes at least one positional indicator, including a positional indicator associated with the branch vessel prosthesis for indicating the position of a point along the branch vessel prosthesis predetermined for optimal alignment with the fenestration during deployment.
摘要翻译：用于在主动脉和分支血管中管腔内部署的支架移植系统包括具有与分支血管对齐的开窗的主动脉支架移植物和在近端具有扩口部分和管状部分的分支血管假体。当部署时，分支血管假体的扩张部分保留在主动脉支架移植物内，并且管状部分延伸穿过开窗并进入分支血管。该系统包括至少一个位置指示器，其包括与分支血管假体相关联的位置指示器，用于指示沿着分支血管假体的点的位置，以便在展开期间与开窗最佳对准。

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