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    • 8. 发明授权
    • Method of making reconstructive SIS structure for cartilaginous elements
in situ
    • 原位软骨元件重建SIS结构的方法
    • US5788625A
    • 1998-08-04
    • US628773
    • 1996-04-05
    • Pamela L. PlouharMichael D. DunnJerry L. LowerThomas C. May
    • Pamela L. PlouharMichael D. DunnJerry L. LowerThomas C. May
    • A61L27/00A61B17/04A61B17/28A61F2/00A61F2/02A61F2/30A61F2/38A61F2/40A61F2/42A61F2/44A61F2/04
    • A61F2/3872A61B17/282A61F2/30756A61B17/0482A61B2017/00969A61B2017/320052A61F2/3094A61F2/40A61F2/4261A61F2/442A61F2002/30461A61F2002/30563A61F2002/30971A61F2220/0075A61F2240/001Y10S623/908
    • A reconstructive structure for a cartilaginous element having a plurality of superimposed layers of a small intestine submucosa compressed and secured together and shaped to provide the multi-layered reconstructive element of the anatomical shape of the cartilaginous element to be constructed. The method of forming the reconstructive structure includes superimposing the planar layers of the small intestine compressing, securing and cutting to the desired shape. The superimposing is performed so as to maintain the layers substantially planar prior to compressing and securing. The method of reconstructing a cartilaginous element includes removing at least a portion, if not substantially all of the cartilaginous element, but leaving a seed portion, sculpturing the reconstructive structure to the anatomical shape of the cartilaginous element to be reconstructed; positioning the receptive element adjacent to the seed portion and securing it thereto. To reconstruct a joint having two bones separated by a cartilaginous material, the method includes removing any remaining portions of the cartilaginous material down to a bleeding bone site and positioning and securing the reconstructive element to the bleeding bone site. A barrier layer may be provided between the bleeding bone site and the reconstruction element. Also, a defect site without a bleeding bone site may be created and used with a reconstructive element.
    • 用于软骨元件的重建结构,其具有压缩并固定在一起并成形为提供要构造的软骨元件的解剖形状的多层重建元件的小肠粘膜下层的多个叠层。 形成重建结构的方法包括将小肠的平面层压缩,固定和切割叠加到期望的形状。 执行叠加以在压缩和固定之前将层保持基本上平面。 重建软骨元件的方法包括去除至少一部分(如果不是基本上全部的软骨元件)但留下种子部分,将重建结构雕刻成待重建的软骨元件的解剖形状; 将接受元件定位成与种子部分相邻并将其固定到其上。 为了重建具有由软骨材料分离的两个骨骼的关节,该方法包括将软骨材料的剩余部分移除到出血骨部位并将重建元件定位并固定到出血骨部位。 可以在出血骨部位和重建元件之间设置阻挡层。 此外,可以创建没有出血骨部位的缺损部位并与重建元件一起使用。