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    • 4. 发明授权
    • Imprinted polymeric materials for binding various targets such as viruses
    • 用于结合各种靶标(如病毒)的压印聚合物材料
    • US08138289B2
    • 2012-03-20
    • US12048995
    • 2008-03-14
    • Peter KofinasDaniel Janiak
    • Peter KofinasDaniel Janiak
    • C08F20/00
    • C08F283/00C08F220/60C08F265/00C08F265/10G01N2600/00
    • Imprinted polymeric materials that selectively bind to a template article. Various types of template articles may be targeted by the imprinted polymeric materials, including microorganisms (e.g., viruses or bacteria) or biologic macromolecules (e.g., proteins or DNA). The imprinted polymeric material may be formed by template-directed synthesis using monomer units that interact with the template article. The monomer units are used to form a polymer matrix around the template article. Subsequently, the template article is removed from the polymer matrix. Also disclosed are imprinted polymeric materials comprising a cross-linked polymer matrix, which comprises a polyampholyte polymer. The polymer matrix has a binding cavity capable of selectively binding to a template article. Also disclosed are various uses for such imprinted polymeric materials.
    • 选择性地结合模板制品的压印聚合物材料。 各种类型的模板制品可以由印刷的聚合物材料(包括微生物(例如病毒或细菌)或生物大分子(例如蛋白质或DNA))靶向。 印迹的聚合物材料可以通过使用与模板制品相互作用的单体单元的模板指导合成形成。 单体单元用于在模板制品周围形成聚合物基质。 随后,从聚合物基质中除去模板制品。 还公开了包含交联聚合物基质的印迹聚合物材料,其包含聚阴离子聚合物。 聚合物基质具有能够选择性地结合模板制品的结合腔。 还公开了这种印刷聚合物材料的各种用途。