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1. 发明授权

US5740793A Dry powder inhalation device with elongate carrier for power 失效
标题翻译：干粉吸入装置，带细长载体供电
公开(公告)号：US5740793A
公开(公告)日：1998-04-21
申请号：US471612
申请日：1995-06-06
申请人： Peter D. Hodson , David K. Smith , David J. Velasquez , Anthony C.L. Wass , Clyde D. Calhoun
发明人： Peter D. Hodson , David K. Smith , David J. Velasquez , Anthony C.L. Wass , Clyde D. Calhoun
IPC分类号： A61K9/14 , A61K45/08 , A61K47/30 , A61M15/00 , A61M15/02 , A61M16/00 , A61P11/00 , B05D7/14 , B65D83/06
CPC分类号： A61M15/0045 , A61M15/0006 , A61M15/0016 , A61M15/0025 , A61M15/0028 , A61M15/0043 , A61M15/0048 , A61M15/0051 , A61M15/0055 , A61M15/0066 , A61M15/0078 , A61M15/0085 , A61M15/0091 , A61M15/02 , A61M2016/0024 , A61M2202/064 , A61M2205/8206
摘要： A dry powder inhalation device comprising a housing defining a chamber in communication with a patient port in the form of a mouthpiece or nasal adaptor, and an elongate carrier bearing a powdered medicament, the device being constructed and arranged such that areas of predetermined size of the elongate carrier may sequentially be exposed within the chamber, the device comprising one or more air inlets such that when a patient inhales through the patient port an air flow is established from the air inlet(s) to the patient port through the chamber such that particles of the powdered medicament of respirable size from said exposed area of the elongate carrier are entrained within the air flow.
摘要翻译：一种干粉吸入装置，其特征在于，包括壳体，所述壳体限定与所述口部或鼻部适配器形式的患者端口连通的室，以及承载有粉末状药物的细长载体，所述装置被构造和布置成使得预定尺寸的细长的载体可以顺序地在腔室内暴露，该装置包括一个或多个空气入口，使得当患者通过患者端口吸入时，通过腔室从空气入口到患者端口建立空气流，使得颗粒的来自所述细长载体的所述暴露区域的可吸入尺寸的粉末状药物被夹带在空气流中。

2. 发明授权

US5192548A Device 失效
标题翻译：设备
公开(公告)号：US5192548A
公开(公告)日：1993-03-09
申请号：US516327
申请日：1990-04-30
申请人： David J. Velasquez , Peter D. Hodson , Clyde D. Calhoun
发明人： David J. Velasquez , Peter D. Hodson , Clyde D. Calhoun
IPC分类号： A61J3/00 , A61J3/02 , A61K9/00 , A61L15/44 , A61M13/00 , A61M15/00 , A61M15/02
CPC分类号： A61K9/0075 , A61J3/00 , A61M15/0045 , A61M15/0051 , A61M15/02 , B29C65/18 , B29C66/81457 , B29C66/83413 , B29K2821/00 , B29L2031/7164 , B29L2031/753
摘要： A sheet material comprising discrete depressions which are at least partially filled with micronized medicament and which are useful as or in a drug delivery device. This sheet material is useful in devices which provide for aerosolization of the medicament, for delivery to a patient by inhalation.

3. 发明授权

US06696286B1 Method and devices for detecting and enumerating microorganisms 失效
标题翻译：用于检测和列举微生物的方法和装置
公开(公告)号：US06696286B1
公开(公告)日：2004-02-24
申请号：US09495092
申请日：2000-02-01
申请人： Kurt J. Halverson , Ai-Ping Wei , Jean Qiu , Clyde D. Calhoun , James G. Berg , James G. Bentsen , Raymond P. Johnston
发明人： Kurt J. Halverson , Ai-Ping Wei , Jean Qiu , Clyde D. Calhoun , James G. Berg , James G. Bentsen , Raymond P. Johnston
IPC分类号： C12M134
CPC分类号： C12Q1/02
摘要： A method for detecting a microorganism in a test sample is described. The method involves distributing microvolumes of a sample to a plurality of microcompartments of a culture device, incubating for a time sufficient to permit at least one cell division cycle of the microorganism, then detecting the presence or absence of the microorganism in the microcompartments. Also disclosed are devices for carrying out these methods.
摘要翻译：描述了测试样品中微生物检测方法。该方法包括将样品的微量体积分配到培养装置的多个微室中，孵育足以允许微生物的至少一个细胞分裂周期的时间，然后检测微室中的微生物的存在或不存在。还公开了用于执行这些方法的装置。

4. 发明授权

US5897930A Multiple embossed webs 失效
标题翻译：多个压花网
公开(公告)号：US5897930A
公开(公告)日：1999-04-27
申请号：US775736
申请日：1996-12-31
申请人： Clyde D. Calhoun , David C. Koskenmaki
发明人： Clyde D. Calhoun , David C. Koskenmaki
IPC分类号： B29C59/02 , B29C59/04 , C09J7/02 , A61F13/02 , E04F15/16
CPC分类号： C09J7/0232 , B29C59/022 , C09J7/0207 , C09J7/026 , B29C2059/023 , B29C2791/001 , B29C59/04 , Y10T428/1476 , Y10T428/24479
摘要： A carrier web having at least one surface that is multiple, sequentially embossed, wherein depressions created from the prior embossing patterns(s) are preserved during the subsequent embossing pattern(s) even though the subsequent embossing pattern(s) are superimposed on the depressions from the prior embossing pattern(s). The patterns of embossing can be Euclidean or fractal created from machine tools produced using microreplication and other techniques. The carrier webs are useful for release liners for pressure sensitive adhesives and a number of other industrial and consumer applications.
摘要翻译：具有多个，顺序压花的至少一个表面的载体网，其中在随后的压花图案期间保留从现有压花图案产生的凹陷，即使随后的压印图案叠加在凹陷上从现有的压花图案。压纹的图案可以是使用微复制和其他技术生产的机床产生的欧几里得或分形。载体网可用于压敏粘合剂和许多其它工业和消费应用的剥离衬垫。

5. 发明授权

US5820450A Abrasive article having precise lateral spacing between abrasive composite members 失效
公开(公告)号：US5820450A
公开(公告)日：1998-10-13
申请号：US857672
申请日：1997-05-19
申请人： Clyde D. Calhoun
发明人： Clyde D. Calhoun
IPC分类号： B24D11/00 , B24D11/06 , B24D15/04
CPC分类号： B24D11/005
摘要： The present invention provides a method of forming an abrasive article comprising the steps of providing an embossed carrier web having a plurality of recesses formed in the front surface thereof; filling the recesses with an abrasive composite slurry that includes a plurality of abrasive grains dispersed in a hardenable binder precursor, hardening the binder precursor to form individual abrasive composite members, laminating a backing sheet to the front surface of the embossed carrier web. The resulting article includes a plurality of precisely spaced abrasive composite members, positioned in a predetermined pattern and orientation on a backing sheet.

6. 发明授权

US5437754A Abrasive article having precise lateral spacing between abrasive composite members 失效
标题翻译：磨料制品在研磨复合构件之间具有精确的横向间距
公开(公告)号：US5437754A
公开(公告)日：1995-08-01
申请号：US820155
申请日：1992-01-13
申请人： Clyde D. Calhoun
发明人： Clyde D. Calhoun
IPC分类号： B24D11/00 , B24D11/06 , B29B11/00
CPC分类号： B24D11/005
摘要： The present invention provides a method of forming an abrasive article comprising the steps of providing an embossed carrier web having a plurality of recesses formed in the front surface thereof; filling the recesses with an abrasive composite slurry that includes a plurality of abrasive grains dispersed in a hardenable binder precursor, hardening the binder precursor to form individual abrasive composite members, laminating a backing sheet to the front surface of the embossed carrier web. The resulting article includes a plurality of precisely spaced abrasive composite members, positioned in a predetermined pattern and orientation on a backing sheet.
摘要翻译：本发明提供一种形成磨料制品的方法，包括以下步骤：提供在其前表面上形成有多个凹槽的压花载体网; 用研磨复合浆料填充凹部，所述磨料复合浆料包括分散在可硬化粘合剂前体中的多个磨料颗粒，硬化粘合剂前体以形成单独的磨料复合构件，将背衬层压合到压花载体网的前表面。所得到的制品包括多个精确间隔的研磨复合构件，其以预定的图案和取向定位在背衬片上。

7. 发明授权

US5328534A Composite including an inorganic image and method of transferring such an image 失效
标题翻译：复合材料包括无机图像和转印这种图像的方法
公开(公告)号：US5328534A
公开(公告)日：1994-07-12
申请号：US21155
申请日：1993-02-22
申请人： Clyde D. Calhoun , David C. Koskenmaki
发明人： Clyde D. Calhoun , David C. Koskenmaki
IPC分类号： B41M5/00 , B05D5/06 , B41M1/22 , B44C1/14 , B44C1/165 , B44C3/08 , H05K3/04 , H05K3/20 , H05K3/38 , B29C41/02
CPC分类号： B44C3/08 , B41M1/22 , B44C1/14 , H05K3/046 , H05K3/20 , H05K2201/0317 , H05K3/386 , Y10T156/1023 , Y10T156/1039 , Y10T156/1041
摘要： A method of forming a transferable pattern or image of an inorganic film by coating an embossed substrate with an inorganic layer, that may comprise one or more films, over both recessed and raised surface portions, adhesively laminating a transfer substrate to the inorganic layer coating the raised surface portions of the embossed substrate and separating the embossed substrate and the transfer substrate. The adhesive is selected such that the bond between the transfer substrate and the inorganic film on the raised surface portions is greater than the bond between the inorganic layer on the raised surface portions and the embossed substrate.The embossed substrate resulting after removal of the inorganic layer coating the raised surface portions may be modified to include additional inorganic layers over the recessed surface portions by tinning or electroplating methods such that this thickened inorganic layer may also be transferred from the embossed substrate to a transfer substrate as set forth above.
摘要翻译：通过在两个凹凸表面部分上涂覆可以包含一个或多个膜的无机层的压花基材来形成无机膜的可转移图案或图像的方法，将转印基材粘附到无机层上涂布压花基板的凸起表面部分并分离压花基板和转印基板。选择粘合剂使得转印衬底和凸起表面部分上的无机膜之间的结合大于凸起表面部分上的无机层与压花衬底之间的结合。在除去涂覆凸起表面部分的无机层之后产生的压花基材可以通过镀锡或电镀方法改性成在凹面部分上包括额外的无机层，使得该增厚的无机层也可以从压花基底转移到转印底物如上所述。

8. 发明授权

US5226210A Method of forming metal fiber mat/polymer composite 失效
标题翻译：形成金属纤维毡/聚合物复合材料的方法
公开(公告)号：US5226210A
公开(公告)日：1993-07-13
申请号：US823151
申请日：1992-01-21
申请人： David C. Koskenmaki , Clyde D. Calhoun , Pamela S. Tucker , Robert L. Lambert, Jr.
发明人： David C. Koskenmaki , Clyde D. Calhoun , Pamela S. Tucker , Robert L. Lambert, Jr.
IPC分类号： B29C70/08 , B29C70/12 , B29C70/50 , B29C70/88 , B32B15/02 , H01B1/22
CPC分类号： H01B1/22 , B29C70/086 , B29C70/088 , B29C70/12 , B29C70/508 , B29C70/885 , B32B15/02 , H05K9/009 , B29K2105/12 , B29K2305/00 , B29K2705/00 , B29K2995/0005 , Y10T29/49988 , Y10T428/12347 , Y10T428/12444 , Y10T428/12583 , Y10T442/655
摘要： The present invention provides a metal/polymer composite comprising a polymeric substrate and a sintered mat of randomly-oriented metal fibers embedded therein, the fibers having a substantially circular cross-section and a diameter of about 10 to 200 .mu.m. The polymeric substrate is typically a thin, flexible sheet-like material having a pair of planar surfaces. The polymeric substrate is preferably thermoformable. If thermoformability is desired the metal will have a melting point of less than the thermoforming temperature of the polymeric substrate. The thermoformable metal/polymer composite of the present invention may be stretched to at least 20%, and often can be stretched at least 200% of its original dimensions, at least in certain regions, without loss of electrical continuity or EMI shielding properties. The present invention also provides a method of making a metal/polymer composite and a sintered mat of randomly-oriented metal fibers.
摘要翻译：本发明提供一种金属/聚合物复合材料，其包含聚合物基材和嵌入其中的随机取向的金属纤维的烧结垫，所述纤维具有基本圆形的横截面和约10至200μm的直径。聚合物基材通常是具有一对平坦表面的薄的柔性片状材料。聚合物基材优选是可热成型的。如果需要热成型，金属的熔点将低于聚合物基材的热成型温度。本发明的可热成型金属/聚合物复合材料可以被拉伸至至少20％，并且通常至少在某些区域可被拉伸至其原始尺寸的至少200％，而不损失电连续性或EMI屏蔽性能。本发明还提供一种制备金属/聚合物复合材料和随机取向的金属纤维的烧结垫的方法。

9. 发明授权

US5216543A Apparatus and method for patterning a film 失效
标题翻译：用于图案化膜的装置和方法
公开(公告)号：US5216543A
公开(公告)日：1993-06-01
申请号：US21458
申请日：1987-03-04
申请人： Clyde D. Calhoun
发明人： Clyde D. Calhoun
IPC分类号： B23K26/00 , B23K26/067 , G02B3/00 , H01L31/0232
CPC分类号： G02B3/005 , B23K26/0006 , B23K26/067 , B23K26/0676 , H01L31/0232 , B23K2201/40 , B23K2203/08 , B23K2203/10 , B23K2203/14 , B23K2203/172 , B23K2203/26 , B23K2203/42 , B23K2203/50 , Y10S430/147 , Y10T428/24917 , Y10T428/2804 , Y10T428/2848
摘要： The present invention relates to an apparatus and method for patterning areas of a radiation absorbent film material. In the preferred embodiment, the film material is at least partially electrically conductive. The radiation is focused onto the film by a lenticular lens having a plurality of optically active elements to provide a radiation pattern on the film and remove or displace portions of the film to form a corresponding pattern, preferably a conductive pattern. The film may have one or more layers or regions, but at least one region must be radiation absorbent in order to allow the formation of patterns in the film in accordance with the present invention. The areas of the film affected by the phenomenon of radiation absorption are non-conductive voids which may separate the film into a plurality of conductive grid lines whereby the film is useful with a conductive lens film to increase the apparent efficiency of a photovoltaic cell.
摘要翻译：本发明涉及一种用于图案化放射线吸收膜材料的区域的装置和方法。在优选实施例中，薄膜材料至少部分导电。通过具有多个光学活性元件的双凸透镜将辐射聚焦到膜上，以在膜上提供辐射图案，并移除或取代膜的部分以形成相应的图案，优选导电图案。膜可以具有一个或多个层或区域，但是至少一个区域必须是辐射吸收剂，以便允许根据本发明在膜中形成图案。受辐射吸收现象影响的膜的区域是非导电空隙，其可以将膜分离成多个导电栅格线，由此该膜可用于导电透镜膜以增加光伏电池的表观效率。

10. 发明授权

US06911243B2 Adhesives having a microreplicated topography and methods of making and using same 有权
标题翻译：具有微复制地形的粘合剂及其制造和使用方法
公开(公告)号：US06911243B2
公开(公告)日：2005-06-28
申请号：US10427010
申请日：2003-04-30
申请人： Frank T. Sher , Larry A. Meixner , Francis V. Loncar, Jr. , Clyde D. Calhoun
发明人： Frank T. Sher , Larry A. Meixner , Francis V. Loncar, Jr. , Clyde D. Calhoun
IPC分类号： B32B7/02 , B29C59/02 , C09J5/00 , C09J5/08 , C09J7/02 , B32B9/00
CPC分类号： C09J5/08 , B33Y80/00 , C09J7/20 , C09J7/22 , C09J7/38 , C09J2201/28 , Y10T428/14 , Y10T428/1486 , Y10T428/149 , Y10T428/1495 , Y10T428/24372 , Y10T428/24405 , Y10T428/24479 , Y10T428/24504 , Y10T428/2457 , Y10T428/24587 , Y10T428/2486
摘要： Adhesives having a microreplicated topography are prepared from contacting a microembossed pattern to a layer of adhesive. When an adhesion interface is established between the layer of adhesive and a supporting substrate, the topography of the adhesive surface controls the performance of the adhesion interface. Articles having microreplicated adhesive surfaces are also disclosed that have an advantage of providing microchannels for fluid egress for an effective period of time. Multiple microeombossed patterns produce microreplicated adhesive surfaces having both microchannels for fluid egress and pegs for improved adhesive properties.
摘要翻译：具有微复制形貌的粘合剂是通过将微压纹图案与粘合剂层接触来制备的。当在粘合剂层和支撑基底之间建立粘合界面时，粘合剂表面的形貌控制粘合界面的性能。还公开了具有微复制粘合剂表面的制品，其具有在有效时间段内为流体出口提供微通道的优点。多个微生物模式产生具有用于流体出口的微通道和用于改善粘合剂性质的钉的微复制粘合剂表面。

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