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1. 发明授权

US06317619B1 Apparatus, methods, and devices for magnetic resonance imaging controlled by the position of a moveable RF coil 失效
标题翻译：用于由可移动RF线圈的位置控制的磁共振成像的装置，方法和装置
公开(公告)号：US06317619B1
公开(公告)日：2001-11-13
申请号：US09363349
申请日：1999-07-29
申请人： Peter Boernert , Tobias Richard Schaeffter , Steffen Weiss
发明人： Peter Boernert , Tobias Richard Schaeffter , Steffen Weiss
IPC分类号： A61B5055
CPC分类号： G01R33/341 , G01R33/34007 , G01R33/3806 , G01R33/543 , G01R33/546 , G01R33/58
摘要： Objects of this invention include provision of magnetic resonance (MR) imaging methods, MR apparatus, and radio-frequency (RF) receiving coil devices permitting interactive MR examination of a patient. In particular, this invention includes means for generating MR images by a moveable RF coil which can be moved across a patient during an MR examination. The MR apparatus includes a position detection system which detects the current position and orientation of the moveable RF coil. The coil can be hand held for manual movement or can be attached to mechanical manipulators for controlled movement. The imaging methods determine and generate magnetic gradient and RF pulse sequences to excite nuclear magnetization in a 3D region determined with respect to the current 3D position and 3D orientation of the moveable RF coil. The invention also includes moveable RF coils for receiving and transmitting which are configured and sized for convenient manipulation by an operator. A preferable moveable RF coil assembly includes markers necessary to interact with a particular position detection system, display means for displaying reconstructed images in real-time, and control means for operator entry of signals controlling the MR apparatus. This invention also includes a carrier medium with recorded program instructions for controlling a programmable MR apparatus to perform the disclosed methods.
摘要翻译：本发明的目的包括提供磁共振（MR）成像方法，MR装置和允许患者的交互式MR检查的射频（RF）接收线圈装置。具体地，本发明包括用于通过可移动RF线圈产生MR图像的装置，其可以在MR检查期间跨越患者移动。 MR装置包括检测可动RF线圈的当前位置和方向的位置检测系统。线圈可以手持进行手动运动，也可以连接到机械操纵器上以进行控制运动。成像方法确定并产生磁梯度和RF脉冲序列，以在相对于可移动RF线圈的当前3D位置和3D取向确定的3D区域中激发核磁化。本发明还包括用于接收和发送的可移动RF线圈，其被配置和大小以便操作者方便操作。优选的可动RF线圈组件包括与特定位置检测系统相互作用所需的标记，用于实时显示重建图像的显示装置和用于操作者输入控制该MR装置的信号的控制装置。本发明还包括具有用于控制可编程MR装置以执行所公开的方法的记录的程序指令的载体介质。

2. 发明申请

US20090080750A1 PASSIVE MR VISUALISATION OF INTERVENTIONAL INSTRUMENTS 审中-公开
标题翻译：传统仪器的被动MR可视化
公开(公告)号：US20090080750A1
公开(公告)日：2009-03-26
申请号：US12297649
申请日：2007-04-17
申请人： Sascha Krueger , Steffen Weiss , Hannes Dahnke , Tobias Richard Schaeffter
发明人： Sascha Krueger , Steffen Weiss , Hannes Dahnke , Tobias Richard Schaeffter
IPC分类号： G06K9/00
CPC分类号： G01R33/286
摘要： The invention relates to a device for magnetic resonance imaging of a body (7), wherein the device (1) is arranged to a) generate a series of MR echo signals (20) by subjecting at least a portion of the body (7) to an MR imaging sequence comprising RF pulses and switched magnetic field gradients, b) acquire the MR echo signals for reconstructing an MR image (21) therefrom, c) calculate a susceptibility gradient map (22) from the MR echo signals or from the MR image (21), the susceptibility gradient map (22) indicating local susceptibility induced magnetic field gradients, d) determine the position of an interventional instrument (16) having paramagnetic or ferromagnetic properties from the susceptibility gradient map (22).
摘要翻译：本发明涉及一种用于身体（7）的磁共振成像的装置，其中所述装置（1）被布置成：a）通过对所述主体（7）的至少一部分进行承受来产生一系列MR回波信号（20）涉及包括RF脉冲和切换磁场梯度的MR成像序列，b）获取用于重构MR图像（21）的MR回波信号，c）从MR回波信号或从MR回波信号计算磁敏度梯度图（22）图像（21），表示局部敏感性感应磁场梯度的磁敏度梯度图（22），d）从磁敏度梯度图（22）确定具有顺磁性或铁磁性质的介入仪器（16）的位置。

3. 发明授权

US09968277B2 Magnetic resonance guidance of a shaft to a target zone 有权
公开(公告)号：US09968277B2
公开(公告)日：2018-05-15
申请号：US14007990
申请日：2012-04-04
申请人： Steffen Weiss , Ronaldus Frederik Johannes Holthuizen , Sascha Krueger , Peter Koken , Daniel Wirtz , Thomas Erik Amthor , Falk Uhlemann
发明人： Steffen Weiss , Ronaldus Frederik Johannes Holthuizen , Sascha Krueger , Peter Koken , Daniel Wirtz , Thomas Erik Amthor , Falk Uhlemann
IPC分类号： A61B5/055 , G01R33/28 , A61B5/06 , A61B5/00 , G01R33/34
CPC分类号： A61B5/055 , A61B5/064 , A61B5/6832 , A61B5/72 , G01R33/287 , G01R33/34084
摘要： A medical apparatus (1100) comprising a magnetic resonance imaging system and an interventional device (300) comprising a shaft (302, 1014, 1120). The medical apparatus further comprises a toroidal magnetic resonance fiducial marker (306, 600, 800, 900, 1000, 1122) attached to the shaft. The shaft passes through a center point (610, 810, 908, 1006) of the fiducial marker. The medical apparatus further comprises machine executable instructions (1150, 1152, 1154, 1156, 1158) for execution by a processor. The instructions cause the processor to acquire (100, 200) magnetic resonance data, to reconstruct (102, 202) a magnetic resonance image (1142), and to receive (104, 204) the selection of a target volume (1118, 1144, 1168). The instructions further cause the processor to repeatedly: acquire (106, 206) magnetic resonance location data (1146) from the fiducial marker and render (108, 212) a view (1148, 1162) indicating the position of the shaft relative to the target zone.

4. 发明授权

US09575146B2 Method of characterizing 有权
标题翻译：表征方法
公开(公告)号：US09575146B2
公开(公告)日：2017-02-21
申请号：US13882293
申请日：2011-10-26
申请人： Johan Van Den Brink , Ingmar Graesslin , Sascha Krueger , Steffen Weiss , Peter Vernickel
发明人： Johan Van Den Brink , Ingmar Graesslin , Sascha Krueger , Steffen Weiss , Peter Vernickel
IPC分类号： G01R33/36 , G01R33/24 , G01R33/44 , G01R33/561 , G01R33/58
CPC分类号： G01R33/36 , G01R33/246 , G01R33/44 , G01R33/5612 , G01R33/583
摘要： The invention relates to a method of characterizing the RF transmit chain of a magnetic resonance imaging scanner (1) using a local transmit/receive coil system (204; 210), comprising a first local NMR probe and a first local magnetic resonance coil, the first NMR probe being spatially located in immediate neighborhood to the first coil, a local receive coil system (206; 208), comprising a second local NMR probe and a second local magnetic resonance coil, the second NMR probe being spatially located in immediate neighborhood to the second coil, wherein the transmit chain comprises an external MR coil (9; 11; 12; 13), the method comprising: determining with the first magnetic resonance coil, a first MR signal phase evolution of the local RF transmit field generated by MR excitation of the first probe using the first magnetic resonance coil by measuring the RF response of the first probe upon said excitation, determining with the second magnetic resonance coil a second MR signal phase evolution of the local RF transmit field generated by MR excitation of the second probe using the external MR coil (9; 11; 12; 13) by measuring the RF response of the second probe upon said excitation, calculating a phase offset between the first and second MR signal phase evolution.
摘要翻译：本发明涉及一种使用本地发射/接收线圈系统（204; 210）来表征磁共振成像扫描仪（1）的RF发射链的方法，该系统包括第一局部NMR探针和第一局部磁共振线圈，空间上位于第一线圈周围的第一NMR探针，包括第二局部NMR探针和第二局部磁共振线圈的局部接收线圈系统（206; 208），所述第二NMR探针在空间上位于紧邻附近所述第二线圈，其中所述发射链包括外部MR线圈（9; 11; 12; 13），所述方法包括：利用所述第一磁共振线圈确定由MR产生的所述本地RF发射场的第一MR信号相位演变通过在所述激发时测量第一探针的RF响应，使用第一磁共振线圈激发第一探针，用第二磁共振线圈确定第二MR信号相位ev 使用外部MR线圈（9; 9）对第二探针的MR激发产生的局部RF发射场的清零。 11; 12; 13）通过在所述激励时测量第二探针的RF响应，计算第一和第二MR信号相位演变之间的相位偏移。

5. 发明授权

US09429637B2 Interventional MR imaging with motion compensation 有权
标题翻译：介入MR成像与运动补偿
公开(公告)号：US09429637B2
公开(公告)日：2016-08-30
申请号：US13266261
申请日：2010-04-14
申请人： Sascha S. Krueger , Steffen Weiss , Bernd David , Oliver Lips , Robert Manzke
发明人： Sascha S. Krueger , Steffen Weiss , Bernd David , Oliver Lips , Robert Manzke
IPC分类号： A61B5/055 , G01R33/567 , A61B5/06 , A61B5/00 , G01R33/28 , G01R33/48 , G01R33/565
CPC分类号： G01R33/5673 , A61B5/055 , A61B5/064 , A61B5/7207 , A61B2034/2051 , G01R33/287 , G01R33/4824 , G01R33/56509
摘要： A method of magnetic resolution (MR) imaging of a moving portion of a body of a patient placed in an examination volume of a MR device. For the purpose of enabling improved interventional MR imaging from acquiring a MR signal data with motion compensation, the invention proposes that the method includes repeated acts of collecting tracking data from an interventional instrument introduced into the portion of the body, subjecting the portion of the body to an imaging sequence for acquiring one or more MR signals therefrom, wherein parameters of the imaging sequence are adjusted on the basis of the tracking data, and reconstructing one or more MR images from the MR signal data set.
摘要翻译：一种放置在MR装置的检查体积中的患者身体的移动部分的磁分辨（MR）成像方法。为了能够通过运动补偿获取MR信号数据来实现改进的介入MR成像，本发明提出了该方法包括从引入到身体部分的介入仪器收集跟踪数据的重复动作，使身体部分涉及从其获取一个或多个MR信号的成像序列，其中基于跟踪数据调整成像序列的参数，以及从MR信号数据集重建一个或多个MR图像。

6. 发明授权

US09348005B2 Interventional or non-interventional instrument for use in an MRI apparatus 有权
标题翻译：用于MRI装置的介入或非介入性仪器
公开(公告)号：US09348005B2
公开(公告)日：2016-05-24
申请号：US14240602
申请日：2012-08-29
申请人： Jouke Smink , Steffen Weiss
发明人： Jouke Smink , Steffen Weiss
IPC分类号： A61B5/05 , G01R33/28 , G01R33/36 , A61B5/01 , A61B5/042 , A61B5/00 , A61B10/02 , A61M25/01 , G01R33/54 , A61B5/055
CPC分类号： G01R33/287 , A61B5/01 , A61B5/042 , A61B5/055 , A61B5/6852 , A61B10/0233 , A61M25/0127 , G01R33/288 , G01R33/3685 , G01R33/54
摘要： An interventional or a non-interventional instrument like a catheter, a surgical device, a biopsy needle, a pointer, a stent or another invasive or non-invasive device, like a position marker, or a surface or local coil like a head coil is disclosed, wherein these instruments are provided with an MR-safe RF transmission line or cable (2, 3) for connecting the instrument with related RF transmit/MR receive units or other signal processing units for operating the instrument during an MR imaging or MR examination of an examination object. Basically, MR safety is obtained or increased by means of a plurality of fuses (6) which are serially connected into the transmission line or cable (2, 3).
摘要翻译：诸如导管，手术装置，活检针，指针，支架或另一侵入性或非侵入性装置（例如位置标记）或诸如头部线圈的表面或局部线圈的介入或非介入手段是公开了这些仪器，其中这些仪器设置有用于在MR成像或MR检查期间将仪器与相关的RF发射/ MR接收单元或其他信号处理单元连接以用于操作仪器的MR安全RF传输线或电缆（2,3）的考试对象。基本上，通过串联连接到传输线或电缆（2,3）中的多个保险丝（6）获得或增加了MR安全性。

7. 发明授权

US08847072B2 Transmission cable for use in radio-frequency magnetic or electrical fields 有权
标题翻译：用于射频磁场或电场的传输电缆
公开(公告)号：US08847072B2
公开(公告)日：2014-09-30
申请号：US12665947
申请日：2008-06-27
申请人： Sascha Krueger , Bernd David , Oliver Lips , Steffen Weiss , Daniel Wirtz
发明人： Sascha Krueger , Bernd David , Oliver Lips , Steffen Weiss , Daniel Wirtz
IPC分类号： H02G3/00 , H01R4/00 , H02G3/06 , H02G15/08 , H01B7/00 , H01B11/02 , H01P1/10 , H01H1/20 , H01H1/36 , G01R33/28 , G01R33/36 , A61B19/00 , A61B18/00 , A61N1/08 , A61B18/14
CPC分类号： G01R33/36 , A61B18/14 , A61B2018/00178 , A61B2090/374 , A61N1/086 , G01R33/287 , G01R33/288 , G01R33/3664
摘要： A transmission cable including a transmission line, at least two electrically conductive line segments separated by a non-conductive gap, a bridging unit including at least one electrically conductive bridge segment capable of bridging the non-conductive gap, and a switching unit arranged to move the bridging unit and/or the transmission line to electrically connect the two line segments by closing the non-conductive gap using the bridge segment or to electrically disconnect the two line segments by opening the non-conductive gap.
摘要翻译：一种传输电缆，包括传输线，由非导电间隙分开的至少两个导电线段，包括能够桥接非导电间隙的至少一个导电桥接段的桥接单元和布置成移动桥接单元和/或传输线，以通过使用桥接段闭合非导电间隙来电连接两个线段，或通过打开非导电间隙来电连接两个线段。

8. 发明申请

US20140121648A1 COMPOSITE FIBER GUIDEWIRES 审中-公开
标题翻译：复合纤维指南
公开(公告)号：US20140121648A1
公开(公告)日：2014-05-01
申请号：US14125737
申请日：2012-06-11
申请人： Steffen Weiss
发明人： Steffen Weiss
IPC分类号： A61M25/09 , B29C70/52
CPC分类号： A61M25/09 , A61B5/01 , A61B5/02154 , A61B5/055 , A61B5/11 , A61B5/6851 , A61B2562/12 , A61M2025/09108 , A61M2025/09133 , A61M2025/09175 , B29C70/52
摘要： A guide wire (400, 500, 600, 700, 800, 900, 1000, 1200, 1300) is adapted for use in magnetic resonance imaging systems. The guide wire has a shaft region (402) and a distal tip region (404). The shaft region comprises a composite shaft (406) comprising reinforcing fibers aligned with a length extension (403) of the shaft region. The fibers extend at least partially into the distal tip region. The fibers form a taper (410) within the distal tip region. The distal tip region comprises a sensor (504, 604, 702, 704, 804, 904, 1006, 1008). The shaft comprises a cable (502, 602, 702, 704, 802, 902, 1002, 1004). The cable is connected to the sensor.
摘要翻译：引导线（400,500,600,700,800,900,1000,1200,1300）适用于磁共振成像系统。引导线具有轴区域（402）和远端尖端区域（404）。轴区域包括复合轴（406），其包括与轴区域的长度延伸部（403）对准的增强纤维。纤维至少部分延伸到远侧末端区域。纤维在远端尖端区域内形成锥形（410）。远端尖端区域包括传感器（504,604,702,704,804,904,1006,1008）。轴包括电缆（502,602,702,704,802,902,1002,1004）。电缆连接到传感器。

9. 发明申请

US20140018664A1 MAGNETIC RESONANCE GUIDANCE OF A SHAFT TO A TARGET ZONE 有权
标题翻译：对目标区域的磁共振指导
公开(公告)号：US20140018664A1
公开(公告)日：2014-01-16
申请号：US14007990
申请日：2012-04-04
申请人： Steffen Weiss , Ronaldus Frederik Johannes Holthuizen , Sascha Krueger , Peter Koken , Daniel Wirtz , Thomas Erik Amthor , Alk Uhlemann
发明人： Steffen Weiss , Ronaldus Frederik Johannes Holthuizen , Sascha Krueger , Peter Koken , Daniel Wirtz , Thomas Erik Amthor , Alk Uhlemann
IPC分类号： A61B5/055 , A61B5/00 , A61B5/06
CPC分类号： A61B5/055 , A61B5/064 , A61B5/6832 , A61B5/72 , G01R33/287 , G01R33/34084
摘要： A medical apparatus (1100) comprising a magnetic resonance imaging system and an interventional device (300) comprising a shaft (302, 1014, 1120). The medical apparatus further comprises a toroidal magnetic resonance fiducial marker (306, 600, 800, 900, 1000, 1122) attached to the shaft. The shaft passes through a center point (610, 810, 908, 1006) of the fiducial marker. The medical apparatus further comprises machine executable instructions (1150, 1152, 1154, 1156, 1158) for execution by a processor. The instructions cause the processor to acquire (100, 200) magnetic resonance data, to reconstruct (102, 202) a magnetic resonance image (1142), and to receive (104, 204) the selection of a target volume (1118, 1144, 1168). The instructions further cause the processor to repeatedly: acquire (106, 206) magnetic resonance location data (1146) from the fiducial marker and render (108, 212) a view (1148, 1162) indicating the position of the shaft relative to the target zone.
摘要翻译：一种包括磁共振成像系统和包括轴（302,1014,1120）的介入装置（300）的医疗装置（1100）。医疗装置还包括连接到轴的环形磁共振基准标记（306,600,800,900,1000,1122）。轴通过基准标记的中心点（610,810,908,1006）。医疗设备还包括用于由处理器执行的机器可执行指令（1150,1152,1154,1156,1158）。所述指令使得所述处理器获取（100,200）磁共振数据，以重建（102,202）磁共振图像（1142），并且接收（104,204）所述目标体积（1118,1144， 1168）。所述指令还使所述处理器重复地：从所述基准标记获取（106,206）磁共振位置数据（1146），并且渲染（108,212）指示所述轴相对于所述目标的位置的视图（1148,1162）区。

10. 发明授权

US08628525B2 Wireless interventional device and a system for wireless energy transmission 失效
标题翻译：无线介入设备和无线能量传输系统
公开(公告)号：US08628525B2
公开(公告)日：2014-01-14
申请号：US12519785
申请日：2007-12-17
申请人： Daniel Wirtz , Oliver Lips , Sascha Krueger , Bernd David , Steffen Weiss
发明人： Daniel Wirtz , Oliver Lips , Sascha Krueger , Bernd David , Steffen Weiss
IPC分类号： A61B18/18 , A61B19/00 , A61B5/05 , A61B5/00
CPC分类号： A61B5/07 , A61B5/055 , A61B2017/00221 , A61B2560/0219 , A61N1/3787 , G01R33/287
摘要： An interventional device (12) is configured to be positioned in a body and includes an electrically operable unit (E1, E2) configured to carry out an interaction with the body upon a receipt of electric power. The device further includes a sensor (2) configured for wirelessly receiving electromagnetic energy from a remote source. The sensor is configured as a resonant circuit (2a, 2b) which converts the received electromagnetic energy into the electric power. The electrically operable device may include a diagnostic and/or therapeutic module.
摘要翻译：介入装置（12）被配置为定位在主体中，并且包括电可操作单元（E1，E2），其被配置为在接收到电力时执行与身体的相互作用。该装置还包括被配置为从远程源无线地接收电磁能量的传感器（2）。传感器被配置为将接收到的电磁能转换成电力的谐振电路（2a，2b）。电可操作装置可以包括诊断和/或治疗模块。

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