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1. 发明申请

US20090080750A1 PASSIVE MR VISUALISATION OF INTERVENTIONAL INSTRUMENTS 审中-公开
标题翻译：传统仪器的被动MR可视化
公开(公告)号：US20090080750A1
公开(公告)日：2009-03-26
申请号：US12297649
申请日：2007-04-17
申请人： Sascha Krueger , Steffen Weiss , Hannes Dahnke , Tobias Richard Schaeffter
发明人： Sascha Krueger , Steffen Weiss , Hannes Dahnke , Tobias Richard Schaeffter
IPC分类号： G06K9/00
CPC分类号： G01R33/286
摘要： The invention relates to a device for magnetic resonance imaging of a body (7), wherein the device (1) is arranged to a) generate a series of MR echo signals (20) by subjecting at least a portion of the body (7) to an MR imaging sequence comprising RF pulses and switched magnetic field gradients, b) acquire the MR echo signals for reconstructing an MR image (21) therefrom, c) calculate a susceptibility gradient map (22) from the MR echo signals or from the MR image (21), the susceptibility gradient map (22) indicating local susceptibility induced magnetic field gradients, d) determine the position of an interventional instrument (16) having paramagnetic or ferromagnetic properties from the susceptibility gradient map (22).
摘要翻译：本发明涉及一种用于身体（7）的磁共振成像的装置，其中所述装置（1）被布置成：a）通过对所述主体（7）的至少一部分进行承受来产生一系列MR回波信号（20）涉及包括RF脉冲和切换磁场梯度的MR成像序列，b）获取用于重构MR图像（21）的MR回波信号，c）从MR回波信号或从MR回波信号计算磁敏度梯度图（22）图像（21），表示局部敏感性感应磁场梯度的磁敏度梯度图（22），d）从磁敏度梯度图（22）确定具有顺磁性或铁磁性质的介入仪器（16）的位置。

2. 发明授权

US10265519B2 Radio frequency ablation catheter and magnetic resonance imaging system 有权
公开(公告)号：US10265519B2
公开(公告)日：2019-04-23
申请号：US13503084
申请日：2010-10-25
申请人： Steffen Weiss , Sascha Krueger
发明人： Steffen Weiss , Sascha Krueger
IPC分类号： A61N1/06 , A61B5/042 , A61B18/14 , G01R33/28 , A61B17/00 , A61B18/00 , A61B90/00 , A61N1/08
摘要： A catheter comprising: —a transmission line (104, 106, 924, 1202, 1302, 1902), wherein the transmission line comprises a plurality of radio frequency traps (118, 318, 418, 518, 618, 718, 818, 918, 1018, 1202, 1404); and —a cooling line (104, 304, 1200, 1900) for cooling the plurality of radio frequency traps with a fluid.

3. 发明授权

US09952296B2 Magnetic resonance safety monitoring systems and methods 有权
公开(公告)号：US09952296B2
公开(公告)日：2018-04-24
申请号：US12808404
申请日：2008-12-22
申请人： Sascha Krueger , Daniel Wirtz , Steffen Weiss
发明人： Sascha Krueger , Daniel Wirtz , Steffen Weiss
IPC分类号： A61B5/055 , G08B23/00 , G01R33/28
CPC分类号： G01R33/285 , G01R33/288
摘要： A magnetic resonance method comprises applying a radio frequency excitation in an examination region (14), measuring a magnetic resonance signal generated by the applied radio frequency excitation in a subject (16) in the examination region, monitoring a radio frequency parameter during the applying, and evaluating subject safety based on the monitoring. A magnetic resonance safety monitor (40) comprises an analyzer (42, 44, 46, 50) configured to (i) receive a radio frequency signal during magnetic resonance excitation, (ii) extract a radio frequency parameter from the received radio frequency signal, and (iii) evaluate subject safety based on the extracted radio frequency parameter, and a remediation module (54) configured to perform a remediation of the magnetic resonance excitation responsive to the evaluation (iii) indicating a potentially unsafe condition.

4. 发明授权

US09918653B2 Electrophysiology catheter 有权
公开(公告)号：US09918653B2
公开(公告)日：2018-03-20
申请号：US13142432
申请日：2010-01-07
申请人： Oliver Lips , Bernd David , Sascha Krueger , Steffen Weiss
发明人： Oliver Lips , Bernd David , Sascha Krueger , Steffen Weiss
IPC分类号： A61B5/053 , A61B5/04 , A61B5/042
CPC分类号： A61B5/0422
摘要： The invention relates to electrophysiology catheter systems and their use, such as in an MRI environment, and in particular to analysis of electric signals from such. An electrophysiology (EP) catheter with a plurality of electrically isolated electrode segments arranged in longitudinally spaced bands around the catheter is used to detect electric signals. A workstation receives the electrical signals which are then processed by a processing unit. Electric signals from electrode segments can be used to determine roll angle information of the catheter in relation to patient anatomy by determining signals from electrode segments in contact with tissue. Also, electric signals can be used to extract a reference signal that can be used to correct for gradient induced artifacts.

5. 发明授权

US08565857B2 Catheter and medical assembly 有权
标题翻译：导管和医疗装配
公开(公告)号：US08565857B2
公开(公告)日：2013-10-22
申请号：US12440252
申请日：2007-09-07
申请人： Oliver Lips , Bernd David , Bernhard Gleich , Sascha Krueger , Steffen Weiss , Daniel Wirtz
发明人： Oliver Lips , Bernd David , Bernhard Gleich , Sascha Krueger , Steffen Weiss , Daniel Wirtz
IPC分类号： A61B5/05
CPC分类号： A61B5/042 , A61B5/0428 , A61B5/055 , A61B2562/222 , A61N1/056 , A61N1/086 , A61N1/3625 , A61N1/3718 , G01R33/287
摘要： The present invention relates to a catheter (6) comprising: a connector (65, 66) at a proximal side of the catheter for connecting the catheter to an external signal transmission/receiving unit (10) for transmitting and/or receiving signals, an electrode (63, 64) at a distal side of the catheter, and an electrical connection including an electrical wire (61, 62) for electrically connecting the electrode and the connector for the transmission of signals between the electrode and the connector, wherein the electrical connection has a high electrical resistance of at least 1 kΩ, in particular of at least 5 kΩ. Thus, the present invention provides a solution to prevent excessive heating during EP interventions under MR guidance by using highly resistive wires and or lumped resistors as connections within catheters.
摘要翻译：本发明涉及一种导管（6），包括：在导管的近侧的连接器（65,66），用于将导管连接到用于传输和/或接收信号的外部信号传输/接收单元（10），电极（63,64），以及包括用于电连接电极和连接器以用于在电极和连接器之间传输信号的电线（61,62）的电连接，其中电气连接具有至少1kOmega的高电阻，特别是至少5kOmega。因此，本发明提供了一种解决方案，通过使用高电阻丝和/或集总电阻作为导管内的连接，在MR引导下的EP干预期间防止过度加热。

6. 发明授权

US08339256B2 Radiofrequency safety of switchable segmented transmission lines 有权
标题翻译：可切换分段传输线的射频安全
公开(公告)号：US08339256B2
公开(公告)日：2012-12-25
申请号：US12645549
申请日：2009-12-23
申请人： Steffen Weiss , Oliver Lips , Sascha Krueger
发明人： Steffen Weiss , Oliver Lips , Sascha Krueger
IPC分类号： G08B1/00 , A61B5/05
CPC分类号： G01R33/285 , A61B18/1492 , A61B2034/2051 , A61B2090/374 , A61N1/086 , G01R33/288 , G01R33/3664 , G01R33/3692
摘要： A magnetic resonance imaging (MRI) system includes an interventional instrument and a switched, segmented transmission (Tx) line which ensures safety during an MRI protocol while the interventional instrument is located in the system. The transmission line includes at least two electrically conductive Tx line segments separated by a non-conductive gap. An electrically conductive bridge, having an open and a closed state, and a parallel connected impedance bridge, having a known impedance which suppresses RF current between the line segments, bridge the non-conductive gap. A measurement unit measures the impedance across the Tx line while the conductive bridges are open. The line segments are verified to be decoupled if the measured impedance of the line is substantially equal to that of the impedance bridge.
摘要翻译：磁共振成像（MRI）系统包括介入仪器和切换的分段传输（Tx）线，其在介入仪器位于系统中时确保MRI协议期间的安全性。传输线包括由非导电间隙分开的至少两个导电Tx线段。具有开路和闭合状态的导电桥和平行连接的阻抗桥，其具有抑制线段之间的RF电流的已知阻抗，桥接非导电间隙。测量单元测量Tx导线上的阻抗，同时导电桥断开。如果线路的测量阻抗基本上等于阻抗桥的阻抗，则线段被验证为去耦合。

7. 发明授权

US08260433B2 Apparatus and method for applying energy within an object 有权
标题翻译：在物体内施加能量的装置和方法
公开(公告)号：US08260433B2
公开(公告)日：2012-09-04
申请号：US12529366
申请日：2008-03-03
申请人： Bernd David , Daniel Wirtz , Oliver Lips , Steffen Weiss , Sascha Krueger
发明人： Bernd David , Daniel Wirtz , Oliver Lips , Steffen Weiss , Sascha Krueger
IPC分类号： A61N1/00
CPC分类号： A61N1/08 , A61B5/055 , A61B2562/222 , A61N1/086 , A61N1/3718
摘要： An apparatus for applying energy within an object includes an energy applying unit having an energy emitting element or outputting energy within the object and an energy storage unit locatable within the object and coupled to the energy emitting element. The apparatus further includes an electrical control line coupled to the energy applying unit for controlling the application of energy within the object by controlling transmission of energy from the energy storage unit to the energy emitting element.
摘要翻译：用于在物体内施加能量的装置包括具有能量发射元件或在物体内输出能量的能量施加单元和位于物体内的能量存储单元，并耦合到能量发射元件。该装置还包括耦合到能量施加单元的电气控制线，用于通过控制从能量存储单元到能量发射元件的能量传输来控制物体内的能量的施加。

8. 发明申请

US20120101362A1 CATHETER BEING USABLE IN A MAGNETIC RESONANCE IMAGING SYSTEM 审中-公开
标题翻译：导管可用于磁共振成像系统
公开(公告)号：US20120101362A1
公开(公告)日：2012-04-26
申请号：US13142426
申请日：2010-01-11
申请人： Steffen Weiss , Oliver Lips , Sascha Krueger , Bernd David
发明人： Steffen Weiss , Oliver Lips , Sascha Krueger , Bernd David
IPC分类号： A61B5/055
CPC分类号： A61M25/0021 , A61B18/1492 , A61B2018/00023 , A61B2018/00029 , A61B2018/00744 , A61B2034/2051 , A61B2090/374 , A61B2090/3954 , A61M25/0082 , A61M25/10 , A61M2025/0166 , G01R33/287
摘要： The present invention relates to a catheter (2) for applying energy to an object (6) and a magnetic resonance imaging system (1) for localizing the catheter (2). The catheter (2) comprises an energy application element for applying energy to the object (6), and a cavity for providing a magnetic resonance fluid from which magnetic resonance signals generated by the magnetic resonance imaging system (1) are receivable, wherein the cavity is adapted for providing a cooling fluid as the magnetic resonance fluid for cooling the energy application element. The catheter (2) comprises further a tracking coil (15) for tracking the catheter (2), wherein the tracking coil (15) is adapted to receive the magnetic resonance signals from the magnetic resonance fluid. Thus, the magnetic resonance fluid fulfils at least two functions, providing magnetic resonance signals for tracking the catheter (2) and cooling the energy application element.
摘要翻译：本发明涉及一种用于向物体（6）施加能量的导管（2）和用于定位导管（2）的磁共振成像系统（1）。导管（2）包括用于向物体（6）施加能量的能量施加元件，以及用于提供磁共振流体的空腔，可由磁共振成像系统（1）产生的磁共振信号从该共振流体接收，其中腔适于提供作为用于冷却能量施加元件的磁共振流体的冷却流体。导管（2）还包括用于跟踪导管（2）的跟踪线圈（15），其中跟踪线圈（15）适于接收来自磁共振流体的磁共振信号。因此，磁共振流体实现至少两个功能，提供用于跟踪导管（2）并冷却能量施加元件的磁共振信号。

9. 发明申请

US20100016934A1 APPARATUS AND METHOD FOR APPLYING ENERGY WITHIN AN OBJECT 有权
标题翻译：在对象中应用能量的装置和方法
公开(公告)号：US20100016934A1
公开(公告)日：2010-01-21
申请号：US12529366
申请日：2008-03-03
申请人： Bernd David , Daniel Wirtz , Oliver Lips , Steffen Weiss , Sascha Krueger
发明人： Bernd David , Daniel Wirtz , Oliver Lips , Steffen Weiss , Sascha Krueger
IPC分类号： A61N1/00
CPC分类号： A61N1/08 , A61B5/055 , A61B2562/222 , A61N1/086 , A61N1/3718
摘要： The invention relates to an apparatus for applying energy within an object. The apparatus comprises an energy applying unit (8, 9), which includes an energy emitting element (9) for outputting energy within the object and an energy storage unit (8) locatable within the object and coupled to the energy emitting element. The apparatus comprises further an electrical control line (12) coupled to the energy applying unit for controlling the application of energy within the object by controlling a transmission of energy from the energy storage unit to the energy emitting element. The invention relates further to a corresponding method and a corresponding computer program.
摘要翻译：本发明涉及一种在物体内施加能量的装置。该装置包括能量施加单元（8,9），其包括用于在物体内输出能量的能量发射元件（9）和位于物体内的能量存储单元（8），并耦合到能量发射元件。该装置还包括耦合到能量施加单元的电气控制线（12），用于通过控制从能量存储单元到能量发射元件的能量传输来控制物体内的能量的施加。本发明进一步涉及相应的方法和相应的计算机程序。

10. 发明申请

US20130241553A1 METHOD OF CHARACTERIZING 有权
标题翻译：表征方法
公开(公告)号：US20130241553A1
公开(公告)日：2013-09-19
申请号：US13882293
申请日：2011-10-26
申请人： Johan Van Den Brink , Ingmar Graesslin , Sascha Krueger , Steffen Weiss , Peter Vernickel
发明人： Johan Van Den Brink , Ingmar Graesslin , Sascha Krueger , Steffen Weiss , Peter Vernickel
IPC分类号： G01R33/36 , G01R33/44
CPC分类号： G01R33/36 , G01R33/246 , G01R33/44 , G01R33/5612 , G01R33/583
摘要： The invention relates to a method of characterizing the RF transmit chain of a magnetic resonance imaging scanner (1) using a local transmit/receive coil system (204; 210), comprising a first local NMR probe and a first local magnetic resonance coil, the first NMR probe being spatially located in immediate neighborhood to the first coil, a local receive coil system (206; 208), comprising a second local NMR probe and a second local magnetic resonance coil, the second NMR probe being spatially located in immediate neighborhood to the second coil, wherein the transmit chain comprises an external MR coil (9; 11; 12; 13), the method comprising: determining with the first magnetic resonance coil, a first MR signal phase evolution of the local RF transmit field generated by MR excitation of the first probe using the first magnetic resonance coil by measuring the RF response of the first probe upon said excitation, determining with the second magnetic resonance coil a second MR signal phase evolution of the local RF transmit field generated by MR excitation of the second probe using the external MR coil (9; 11; 12; 13) by measuring the RF response of the second probe upon said excitation, calculating a phase offset between the first and second MR signal phase evolution.
摘要翻译：本发明涉及一种使用本地发射/接收线圈系统（204; 210）来表征磁共振成像扫描仪（1）的RF发射链的方法，该系统包括第一局部NMR探针和第一局部磁共振线圈，空间上位于第一线圈周围的第一NMR探针，包括第二局部NMR探针和第二局部磁共振线圈的局部接收线圈系统（206; 208），所述第二NMR探针在空间上位于紧邻附近所述第二线圈，其中所述发射链包括外部MR线圈（9; 11; 12; 13），所述方法包括：利用所述第一磁共振线圈确定由MR产生的所述本地RF发射场的第一MR信号相位演变通过在所述激发时测量第一探针的RF响应，使用第一磁共振线圈激发第一探针，用第二磁共振线圈确定第二MR信号相位ev 使用外部MR线圈（9; 9）对第二探针的MR激发产生的局部RF发射场的清零。 11; 12; 13）通过在所述激励时测量第二探针的RF响应，计算第一和第二MR信号相位演变之间的相位偏移。

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