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1. 外观设计

USD593562S1 Bezel for information handling system housing 有权
标题翻译：信息处理系统住房用挡板
公开(公告)号：USD593562S1
公开(公告)日：2009-06-02
申请号：US29326152
申请日：2008-10-13
申请人： Pedro Alfonso , Donald C. Guthan, Jr.
设计人： Pedro Alfonso , Donald C. Guthan, Jr.

2. 外观设计

USD593563S1 Bezel for information handling system housing 有权
公开(公告)号：USD593563S1
公开(公告)日：2009-06-02
申请号：US29326154
申请日：2008-10-13
申请人： Pedro Alfonso , Donald C. Guthan, Jr.
设计人： Pedro Alfonso , Donald C. Guthan, Jr.

3. 发明申请

US20090062510A1 Human Chemotactic Cytokine I Polypeptides 审中-公开
标题翻译：人类趋化细胞因子I多肽
公开(公告)号：US20090062510A1
公开(公告)日：2009-03-05
申请号：US11737622
申请日：2007-04-19
申请人： Jian Ni , Guo-Liang Yu , Pedro Alfonso , Reiner L. Gentz , Jeffrey Y. Su
发明人： Jian Ni , Guo-Liang Yu , Pedro Alfonso , Reiner L. Gentz , Jeffrey Y. Su
IPC分类号： C07K14/52
CPC分类号： C07K14/52 , C07H21/04
摘要： Human chemotactic cytokine I polypeptides and DNA (RNA) encoding such chemotactic cytokines and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such chemotactic cytokines for the treatment of leukemia, tumors, chronic infections, auto-immune disease, fibrotic disorders, wound healing and psoriasis. Antagonists against such chemotactic cytokines and their use as a therapeutic to treat rheumatoid arthritis, auto-immune and chronic and acute inflammatory and infective diseases, allergic reactions, prostaglandin-independent fever and bone marrow failure are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to mutations in the nucleic acid sequences and altered concentrations of the polypeptides. Also disclosed are diagnostic assays for detecting mutations in the polynucleotides encoding the chemotactic cytokines and for detecting altered levels of the polypeptide in a host.
摘要翻译：公开了人类趋化性细胞因子I多肽和编码这种趋化性细胞因子的DNA（RNA）以及通过重组技术产生此类多肽的方法。还公开了利用这种趋化性细胞因子治疗白血病，肿瘤，慢性感染，自身免疫疾病，纤维化病症，伤口愈合和牛皮癣的方法。还公开了抗这种趋化性细胞因子的拮抗剂及其作为治疗类风湿性关节炎，自身免疫，慢性和急性炎性和感染性疾病，过敏反应，前列腺素不依赖性发烧和骨髓衰竭的治疗剂的用途。还公开了用于检测与核酸序列中的突变和多肽的改变的浓度相关的疾病的诊断测定。还公开了用于检测编码趋化性细胞因子的多核苷酸中的突变并用于检测宿主中多肽的改变水平的诊断测定。

4. 外观设计

USD585441S1 Information handling system 有权
公开(公告)号：USD585441S1
公开(公告)日：2009-01-27
申请号：US29297449
申请日：2007-11-12
申请人： Pedro Alfonso , Scott Lauffer , Timothy Uys
设计人： Pedro Alfonso , Scott Lauffer , Timothy Uys

5. 发明授权

US07393943B1 Polynucleotides encoding a human chemotactic cytokine I 失效
标题翻译：编码人趋化因子I的多核苷酸
公开(公告)号：US07393943B1
公开(公告)日：2008-07-01
申请号：US08761289
申请日：1996-12-06
申请人： Jian Ni , Guo-Liang Yu , Pedro Alfonso , Reiner Gentz , Jeffrey Y. Su
发明人： Jian Ni , Guo-Liang Yu , Pedro Alfonso , Reiner Gentz , Jeffrey Y. Su
IPC分类号： C07H21/04 , C12P21/06 , C12N1/20 , C12N15/00 , C12N5/00 , C12N5/02 , C12N15/74
CPC分类号： C07K14/52 , C07H21/04
摘要： Human chemotactic cytokine I polypeptides and DNA (RNA) encoding such chemotactic cytokines and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such chemotactic cytokines for the treatment of leukemia, tumors, chronic infections, auto-immune disease, fibrotic disorders, wound healing and psoriasis. Antagonists against such chemotactic cytokines and their use as a therapeutic to treat rheumatoid arthritis, auto-immune and chronic and acute inflammatory and infective diseases, allergic reactions, prostaglandin-independent fever and bone marrow failure are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to mutations in the nucleic acid sequences and altered concentrations of the polypeptides. Also disclosed are diagnostic assays for detecting mutations in the polynucleotides encoding the chemotactic cytokines and for detecting altered levels of the polypeptide in a host.
摘要翻译：公开了人类趋化性细胞因子I多肽和编码这种趋化性细胞因子的DNA（RNA）以及通过重组技术产生此类多肽的方法。还公开了利用这种趋化性细胞因子治疗白血病，肿瘤，慢性感染，自身免疫疾病，纤维化病症，伤口愈合和牛皮癣的方法。还公开了抗这种趋化性细胞因子的拮抗剂及其作为治疗类风湿性关节炎，自身免疫，慢性和急性炎性和感染性疾病，过敏反应，前列腺素不依赖性发烧和骨髓衰竭的治疗剂的用途。还公开了用于检测与核酸序列中的突变和多肽的改变的浓度相关的疾病的诊断测定。还公开了用于检测编码趋化性细胞因子的多核苷酸中的突变并用于检测宿主中多肽的改变水平的诊断测定。

6. 外观设计

USD598440S1 Information handling system rack enclosure 有权
标题翻译：信息处理系统机柜
公开(公告)号：USD598440S1
公开(公告)日：2009-08-18
申请号：US29321820
申请日：2008-07-24
申请人： Pedro Alfonso , Adam M. Ruggles , Aaron vom Eigen
设计人： Pedro Alfonso , Adam M. Ruggles , Aaron vom Eigen

7. 发明授权

US6102218A Computer system including a hanging support bracket 有权
标题翻译：计算机系统包括悬挂支架
公开(公告)号：US6102218A
公开(公告)日：2000-08-15
申请号：US193696
申请日：1998-11-17
申请人： Pedro Alfonso , Benjamin Trapp
发明人： Pedro Alfonso , Benjamin Trapp
IPC分类号： A47B96/06 , A47G29/087
CPC分类号： A47B96/061
摘要： A computer system according to which a bracket supports a computer chassis on a structure having an accessible upper edge. The bracket is formed by a plurality of support members for receiving the chassis and for engaging the chassis in a manner to prevent movement of the chassis relative to the bracket. At least one hook is connected to the support member for extending over the edge to support the support member, and therefore the chassis, relative to the structure.
摘要翻译：一种计算机系统，根据该计算机系统，支架在具有可接近的上边缘的结构上支撑计算机机架。支架由多个支撑构件形成，用于接收底盘并以防止底盘相对于支架移动的方式与底盘接合。至少一个钩连接到支撑构件，用于在边缘上延伸以支撑支撑构件，并且因此相对于结构支撑底盘。

8. 外观设计

USD660841S1 Storage device housing 有权
标题翻译：存储设备外壳
公开(公告)号：USD660841S1
公开(公告)日：2012-05-29
申请号：US29399454
申请日：2011-08-15
申请人： Pedro Alfonso , Robert Moser , Yinggang Du
设计人： Pedro Alfonso , Robert Moser , Yinggang Du

9. 发明申请

US20090171072A1 Process for Preparing Unaggregated Antibody FC Domains 有权
标题翻译：制备未分类抗体FC域的方法
公开(公告)号：US20090171072A1
公开(公告)日：2009-07-02
申请号：US11875243
申请日：2007-10-19
申请人： Pedro Alfonso , Michael Capaldi , Dennis Dong , Thomas R. Gervais , Joshua Goldstein , Allen B. Magill , Nicole Quinlan , Deepak Saini
发明人： Pedro Alfonso , Michael Capaldi , Dennis Dong , Thomas R. Gervais , Joshua Goldstein , Allen B. Magill , Nicole Quinlan , Deepak Saini
IPC分类号： C07K16/00
CPC分类号： A61K39/39591 , B01D15/3809 , C07K1/22 , C07K2317/52 , C07K2319/30
摘要： Methods useful for producing a solution of purified Fc peptide chains are disclosed. The methods employ protein A chromatography to separate high molecular weight, aggregated peptide chains comprising antibody Fc domains from lower molecular weight unaggregated peptide chains that also comprise antibody Fc domains. The solutions of purified Fc peptide chains obtained by the methods of the invention contain less than 5% aggregate and greater than 70% of the Fc peptide chains subjected to purification.
摘要翻译：公开了可用于产生纯化的Fc肽链溶液的方法。该方法采用蛋白A色谱分离从包含抗体Fc结构域的低分子量未聚集肽链分离包含抗体Fc结构域的高分子量聚集肽链。通过本发明方法获得的纯化的Fc肽链的溶液含有少于5％的聚集体和大于70％的经过纯化的Fc肽链。

10. 外观设计

USD593100S1 Bezel for rack storage system 有权
标题翻译：机架存储系统的挡板
公开(公告)号：USD593100S1
公开(公告)日：2009-05-26
申请号：US29320171
申请日：2008-06-23
申请人： Pedro Alfonso , Yinggang Du
设计人： Pedro Alfonso , Yinggang Du

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