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1. 发明授权

US5260222A Device and method for completing a fluidic circuit which employs a liquid expandable piece of bibulous material 失效
标题翻译：用于完成使用吸水材料的液体可膨胀件的流体回路的装置和方法
公开(公告)号：US5260222A
公开(公告)日：1993-11-09
申请号：US874662
申请日：1992-04-27
申请人： Rajesh D. Patel , Nurith Kurn , Martin Becker , Edwin F. Ullman
发明人： Rajesh D. Patel , Nurith Kurn , Martin Becker , Edwin F. Ullman
IPC分类号： B01L3/00 , G01N37/00 , G01N1/10
CPC分类号： B01L3/5023 , B01L2300/0825 , B01L2400/0406 , B01L2400/0633 , B01L2400/0661 , B01L2400/0683 , Y10T436/2575
摘要： Methods and devices for permitting capillary flow of liquid between two or more pieces of bibulous material which, prior to actuation, are in a non-capillary flow relationship. In particular, the device is actuated and a capillary flow relationship is initiated between the two or more pieces of bibulous material in non-capillary flow relationship by utilizing a liquid expandable piece of bibulous material.
摘要翻译：用于允许两个或更多个吸水材料之间的液体的毛细管流动的方法和装置，其在致动之前处于非毛细管流动关系。特别地，该装置被致动，并且通过利用吸水材料的液体可膨胀件，以非毛细管流动关系在两个或多个吸管材料之间开始毛细管流动关系。

2. 发明授权

US5622870A Device and method for completing a fluidic circuit 失效
公开(公告)号：US5622870A
公开(公告)日：1997-04-22
申请号：US453860
申请日：1995-05-30
申请人： N. Chung Sizto , Nurith Kurn , Rajesh D. Patel , Martin Becker , Edwin F. Ullman
发明人： N. Chung Sizto , Nurith Kurn , Rajesh D. Patel , Martin Becker , Edwin F. Ullman
IPC分类号： B01L3/00 , B01L9/00 , G01N33/543 , G01N33/558 , G01N21/00
CPC分类号： G01N33/54366 , B01L3/5023 , B01L2300/0825 , B01L2300/087 , B01L2400/0406 , B01L2400/0633 , B01L9/52 , Y10S435/97 , Y10S435/975 , Y10S436/808 , Y10T436/2575
摘要： Disclosed are assay apparatus, devices and methods that permit longitudinal capillary flow of liquid between two pieces of bibulous material which, prior to actuation, are in a non-capillary flow relationship to each other. In particular, the devices utilize a distortable member which when distorted, actuates the device by creating a capillary flow relationship between the two pieces of bibulous material. In an alternative embodiment the apparatus, devices, and methods include at least one additional piece of bibulous material.

3. 发明授权

US5620657A Device and method for completing a fluidic circuit 失效
标题翻译：用于完成流体回路的装置和方法
公开(公告)号：US5620657A
公开(公告)日：1997-04-15
申请号：US453859
申请日：1995-05-30
申请人： N. Chung Sizto , Nurith Kurn , Rajesh D. Patel , Martin Becker , Edwin F. Ullman
发明人： N. Chung Sizto , Nurith Kurn , Rajesh D. Patel , Martin Becker , Edwin F. Ullman
IPC分类号： B01L3/00 , B01L9/00 , G01N33/543 , G01N33/558 , G01N21/00
CPC分类号： G01N33/54366 , B01L3/5023 , B01L2300/0825 , B01L2300/087 , B01L2400/0406 , B01L2400/0633 , B01L9/52 , Y10S435/97 , Y10S435/975 , Y10S436/808 , Y10T436/2575
摘要： Disclosed are assay apparatus, devices and methods that permit longitudinal capillary flow of liquid between two pieces of bibulous material which, prior to actuation, are in a non-capillary flow relationship to each other. In particular, the devices utilize a distortable member which when distorted, actuates the device by creating a capillary flow relationship between the two pieces of bibulous material. In an alternative embodiment the apparatus, devices, and methods include at least one additional piece of bibulous material.
摘要翻译：公开了允许两片吸水材料之间的液体的纵向毛细管流动的测定装置，装置和方法，其在致动之前彼此处于非毛细管流动关系。特别地，这些装置使用可变形构件，当变形时，通过在两片吸水材料之间产生毛细管流动关系来致动装置。在替代实施例中，装置，装置和方法包括至少一个额外的吸水材料。

4. 发明授权

US5135873A Device and method for completing a fluidic circuit which employs a liquid expandable piece of bibulous material 失效
标题翻译：用于完成使用吸水材料的液体可膨胀件的流体回路的装置和方法
公开(公告)号：US5135873A
公开(公告)日：1992-08-04
申请号：US441665
申请日：1989-11-27
申请人： Rajesh D. Patel , Nurith Kurn , Martin Becker , Edwin F. Ullman
发明人： Rajesh D. Patel , Nurith Kurn , Martin Becker , Edwin F. Ullman
IPC分类号： B01L3/00 , G01N37/00
CPC分类号： B01L3/5023 , B01L2300/0672 , B01L2300/0825 , B01L2400/0406 , B01L2400/0633 , B01L2400/0661 , B01L2400/0683 , Y10T436/2575
摘要： Disclosed are methods and devices for permitting capillary flow of liquid between two or more pieces of bibulous material which, prior to actuation, are in a non-capillary flow relationship. In particular, the device is actuated and a capillary flow relationship is initiated between the two or more pieces of bibulous material in non-capillary flow relationship by utilizing a liquid expandable piece of bibulous material.
摘要翻译：公开了用于允许两个或多个吸水材料之间的液体的毛细管流动的方法和装置，其在致动之前处于非毛细管流动关系。特别地，该装置被致动，并且通过利用吸水材料的液体可膨胀件，以非毛细管流动关系在两个或多个吸管材料之间开始毛细管流动关系。

5. 发明授权

US5104812A Device and method for interrupting capillary flow 失效
标题翻译：用于中断毛细管流动的装置和方法
公开(公告)号：US5104812A
公开(公告)日：1992-04-14
申请号：US441688
申请日：1989-11-27
申请人： Nurith Kurn , Rajesh D. Patel , Martin Becker , Edwin F. Ullman
发明人： Nurith Kurn , Rajesh D. Patel , Martin Becker , Edwin F. Ullman
IPC分类号： G01N33/52 , G01N33/558
CPC分类号： G01N33/558 , G01N33/521 , Y10S435/805 , Y10S435/81 , Y10S436/807 , Y10T436/2575
摘要： Disclosed are devices and methods for interrupting capillary flow of a liquid between two pieces of bibulous material which, prior to actuation, are in a capillary flow relationship to each other. In particular, the capillary flow relationship of two pieces of bibulous material is interrupted by utilizing a liquid expandable piece of bibulous material.
摘要翻译：公开了用于中断两片吸水材料之间的液体的毛细管流动的装置和方法，其在致动之前彼此处于毛细管流动关系中。特别地，通过利用吸水材料的液体可膨胀片，中断两片吸水材料的毛细管流动关系。

6. 发明授权

US5914230A Homogeneous amplification and detection of nucleic acids 失效
标题翻译：核酸的均相扩增和检测
公开(公告)号：US5914230A
公开(公告)日：1999-06-22
申请号：US771624
申请日：1996-12-20
申请人： Yen Ping Liu , Rajesh D. Patel , Nurith Kurn , Claire Lin , Samuel J. Rose , Edwin F. Ullman
发明人： Yen Ping Liu , Rajesh D. Patel , Nurith Kurn , Claire Lin , Samuel J. Rose , Edwin F. Ullman
IPC分类号： G01N33/53 , C12N15/09 , C12Q1/68 , G01N33/566 , C12P19/34
CPC分类号： C12Q1/6816 , C12Q1/6813 , C12Q1/6818 , C12Q1/686
摘要： The present invention relates to a method for detecting or amplifying and detecting a target polynucleotide sequence. The method comprises providing in combination (i) a medium suspected of containing the target polynucleotide sequence, (ii) all reagents required for conducting an amplification of the target polynucleotide sequence when amplification is desired, and (iii) two oligonucleotide probes capable of binding to a single strand of the product of the amplification. At least one of the probes has two sequences that either (i) are non-contiguous and bind to contiguous or non-contiguous sites on the single strand or (ii) can bind to non-contiguous sites on the single strand. Each probe may contain a label. The combination is subjected to conditions for amplifying the target polynucleotide sequence. Next, the combination is subjected to conditions under which both of the probes hybridize to one of the strands to form a termolecular complex, which is detected by means of the label.
摘要翻译：本发明涉及检测或扩增和检测靶多核苷酸序列的方法。所述方法包括组合（i）怀疑含有靶多核苷酸序列的培养基，（ii）当需要扩增时进行靶多核苷酸序列扩增所需的所有试剂，和（iii）能够结合到单链的扩增产物。至少一个探针具有以下两个序列：（i）不连续并且结合单链上的连续或非连续位点，或（ii）可以结合单链上的非连续位点。每个探针可能包含一个标签。将该组合进行扩增靶多核苷酸序列的条件。接下来，将该组合进行两个探针与其中一条链杂交以形成通过标记检测的分子复合物的条件。

7. 发明授权

US5187066A Methods for detecting amphiphilic antigens 失效
标题翻译：检测两亲性抗原的方法
公开(公告)号：US5187066A
公开(公告)日：1993-02-16
申请号：US479930
申请日：1990-02-14
申请人： Martin Becker , Nurith Kurn , Yen P. Liu , Rajesh D. Patel , Thomas M. Houts , John D. Olson
发明人： Martin Becker , Nurith Kurn , Yen P. Liu , Rajesh D. Patel , Thomas M. Houts , John D. Olson
IPC分类号： G01N33/543 , G01N33/569 , G01N33/571
CPC分类号： G01N33/543 , G01N33/56927 , G01N33/571
摘要： This invention is to a method for detecting an amphiphilic antigen in a biological sample suspected of containing the amphiphilic antigen, which method comprises providing in combination a hydrophilic solid support modified to have a hydrophobic surface and an assay medium suspected of containing an amphiphilic antigen, incubating the combination under conditions sufficient for the amphiphilic antigen to bind to the hydrophobic surface, and determining the presence or amount of the amphiphilic antigen bound to the hydrophobic surface.
摘要翻译：本发明涉及一种用于检测怀疑含有两亲性抗原的生物样品中的两亲性抗原的方法，该方法包括组合改性以具有疏水表面的亲水性固体支持物和怀疑含有两亲性抗原的测定培养基所述组合在足以使两亲性抗原结合到疏水性表面的条件下，以及确定与疏水性表面结合的两亲性抗原的存在或量。

8. 发明申请

US20110130016A1 External Quick Connect Modular Plug for a Wiring Device 有权
标题翻译：用于接线设备的外部快速连接模块化插头
公开(公告)号：US20110130016A1
公开(公告)日：2011-06-02
申请号：US12627469
申请日：2009-11-30
申请人： Darron Kirby Lacey , Erik Jeffrey Gouhl , Jim A. Vaccaro , Denis Pierre Chardac , Rajesh D. Patel
发明人： Darron Kirby Lacey , Erik Jeffrey Gouhl , Jim A. Vaccaro , Denis Pierre Chardac , Rajesh D. Patel
IPC分类号： H01R13/648 , H01R24/00 , H01R3/00 , H01R43/00
CPC分类号： H02G3/18 , H01R24/22 , H01R24/30 , Y10T29/49117
摘要： The modular electrical wiring device includes an electrical wiring device and an external plug that is electrically coupled by one or more wires to the wiring device. The modular plug is releasably coupled to a connector in a male-female relationship. Both the modular plug and connector include internal contacts for electrically coupling one to the other. The connector is electrically coupled to and terminates one or more building wires, which are used to provide power to one or more of the wiring devices. The external plug is removably coupled to the connector to provide electrical power to the wiring device by establishing and electrical pathway from a source of electrical power, through the building wires, the connector and the modular plug to the wiring device.
摘要翻译：模块化电气配线装置包括电线路装置和外部插头，其通过一根或多根电线电耦合到配线装置。模块化插头以男女关系可释放地联接到连接器。模块化插头和连接器均包括用于将一个电气连接到另一个的内部触点。连接器电耦合到并终止一个或多个建筑物导线，其用于向一个或多个布线装置提供电力。外部插头可拆卸地联接到连接器，以通过建立从电源，通过建筑物线，连接器和模块化插头到布线装置的电路来向布线装置提供电力。

9. 发明授权

US07433657B2 Apparatus and method for dynamically clocking a loop filter in a digital communications device 有权
标题翻译：用于在数字通信设备中动态计时环路滤波器的装置和方法
公开(公告)号：US07433657B2
公开(公告)日：2008-10-07
申请号：US11268798
申请日：2005-11-08
申请人： Paul Cheng-Po Liang , Rajesh D. Patel
发明人： Paul Cheng-Po Liang , Rajesh D. Patel
IPC分类号： H04B1/16
CPC分类号： H04L27/12 , H04L27/20
摘要： A transmitter has a signal generator, an amplifier, a detection circuit, a comparison circuit, a loop filter, and an adjustable clock. The signal generator produces a signal. The signal is produced with a first frequency characteristic and contains frequency-related information. The detection circuit detects the first frequency-related characteristic and generates an associated signal in response. A comparison circuit compares the signal from the detection circuit and another signal. It outputs a signal associated with the difference between the two. A loop filter receives the output of the comparison circuit and generates a signal to the signal generator in. The loop filter is clocked at a second frequency by a signal from a clock circuit. The clock circuit can compare the first frequency and the second frequency, and can change the second frequency based upon a relationship between the two frequencies.
摘要翻译：发射机具有信号发生器，放大器，检测电路，比较电路，环路滤波器和可调节时钟。信号发生器产生信号。该信号产生具有第一频率特性并且包含频率相关信息。检测电路检测第一频率相关特性并产生响应的相关信号。比较电路将来自检测电路的信号与另一信号进行比较。它输出与两者之间的差异相关联的信号。环路滤波器接收比较电路的输出并产生信号到信号发生器。环路滤波器以来自时钟电路的信号以第二频率被计时。时钟电路可以比较第一频率和第二频率，并且可以基于两个频率之间的关系来改变第二频率。

10. 发明申请

US20110130015A1 External Quick Connect Modular Plug for a Wiring Device 有权
标题翻译：用于接线设备的外部快速连接模块化插头
公开(公告)号：US20110130015A1
公开(公告)日：2011-06-02
申请号：US12627487
申请日：2009-11-30
申请人： Darron Kirby Lacey , Erik Jeffrey Gouhl , Kejie Chen , Chuan Chuan Zhuang , Jim A. Vaccaro , Denis Pierre Chardac , Rajesh D. Patel
发明人： Darron Kirby Lacey , Erik Jeffrey Gouhl , Kejie Chen , Chuan Chuan Zhuang , Jim A. Vaccaro , Denis Pierre Chardac , Rajesh D. Patel
IPC分类号： H01R13/648 , H01R24/00 , H01R3/00
CPC分类号： H02G3/18 , H01R24/22
摘要： The modular electrical wiring device includes an electrical wiring device and an external plug that is electrically coupled by one or more wires to the wiring device. The modular plug is releasably coupled to a connector in a male-female relationship. Both the modular plug and connector include internal contacts for electrically coupling one to the other. The connector is electrically coupled to and directly terminates one or more building wires, which are used to provide power to one or more of the wiring devices. The external plug is removably coupled to the connector to provide electrical power to the wiring device by establishing and electrical pathway from a source of electrical power, through the building wires, the connector and the modular plug to the wiring device.
摘要翻译：模块化电气配线装置包括电线路装置和外部插头，其通过一根或多根电线电耦合到配线装置。模块化插头以男女关系可释放地联接到连接器。模块化插头和连接器均包括用于将一个电气连接到另一个的内部触点。连接器电耦合到并直接终止一个或多个建筑物线，其用于向一个或多个布线装置提供电力。外部插头可拆卸地联接到连接器，以通过建立从电源，通过建筑物线，连接器和模块化插头到布线装置的电路来向布线装置提供电力。

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