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1. 发明授权

US08331531B2 Configurations for integrated MRI-linear accelerators 有权
标题翻译：集成MRI线性加速器的配置
公开(公告)号：US08331531B2
公开(公告)日：2012-12-11
申请号：US12661303
申请日：2010-03-15
申请人： Rebecca Fahrig , Norbert J. Pelc , Kim Pauly , Greig C. Scott , Amit Sawant , Paul J. Keall , Lei Xing , Steven M. Conolly
发明人： Rebecca Fahrig , Norbert J. Pelc , Kim Pauly , Greig C. Scott , Amit Sawant , Paul J. Keall , Lei Xing , Steven M. Conolly
IPC分类号： A61N5/10 , G01N23/04
CPC分类号： G01R33/4808 , A61N5/1049 , A61N5/1067 , A61N2005/1055 , A61N2005/1061 , A61N2005/1087
摘要： The present invention provides a radiotherapy treatment apparatus that includes a treatment beam, a magnetic field disposed parallel collinear to the treatment beam, and a target that is disposed along the treatment beam. The treatment beam can be a charged particle beam, a proton beam, an electron beam, or a linear accelerator (Linac) beam. The magnetic field is from a magnetic resonance imager (MRI), a megavolt x-ray imager, or a kilovolt x-ray imager and is disposed to operate in coordination with operation of the treatment beam and to narrow the beam. The tumor is disposed to rotate with respect to the treatment beam and the magnetic field, or the treatment beam and the magnetic field are disposed to rotate up to 360° with respect to the target when mounted to a ring gantry. The apparatus can include a rotation angle dependent shim disposed to account for Earth's magnetic field.
摘要翻译：本发明提供了一种放射治疗处理装置，其包括处理束，与处理束并行设置的磁场和沿着治疗束设置的靶。处理光束可以是带电粒子束，质子束，电子束或线性加速器（线性加速器）。磁场来自磁共振成像仪（MRI），兆伏X射线成像仪或千伏X射线成像仪，并且被设置为与治疗束的操作协调操作并且使束变窄。肿瘤设置成相对于治疗束和磁场旋转，或者治疗束和磁场被设置为当安装到环形台架时相对于靶旋转高达360度。该装置可以包括设置成考虑地球磁场的旋转角度相关垫片。

2. 发明授权

US08194820B2 Optimal weights for measuring spectral x-ray data 有权
标题翻译：用于测量光谱X射线数据的最佳权重
公开(公告)号：US08194820B2
公开(公告)日：2012-06-05
申请号：US12700558
申请日：2010-02-04
申请人： Adam S. Wang , Norbert J. Pelc
发明人： Adam S. Wang , Norbert J. Pelc
IPC分类号： G01N23/06 , H05G1/64
CPC分类号： G01N23/087
摘要： A method for determining a composition of an object using a spectral x-ray system is provided. X-ray photons of at least two different energies are transmitted through the object. The energy of each detected x-ray photon using a detector in the x-ray system is estimated. A first weighted sum of the number of detected photons of each energy is found using a first weighting function, wherein the first weighting function is dependent on the attenuation coefficient function of a first material. In another embodiment, the photons are binned into two energy bins wherein there is a gap between the energy bins.
摘要翻译：提供了一种使用光谱X射线系统确定物体的组成的方法。至少两种不同能量的X射线光子通过物体传输。使用X射线系统中的检测器估计每个检测到的x射线光子的能量。使用第一加权函数找到每个能量的检测光子数量的第一加权和，其中第一加权函数取决于第一材料的衰减系数函数。在另一个实施例中，光子被分成两个能量箱，其中在能量箱之间存在间隙。

3. 发明授权

US07860210B2 Data normalization in inverse geometry computed tomography system 有权
标题翻译：逆几何计算机断层扫描系统的数据归一化
公开(公告)号：US07860210B2
公开(公告)日：2010-12-28
申请号：US12273223
申请日：2008-11-18
申请人： Norbert J. Pelc , Jongduk Baek
发明人： Norbert J. Pelc , Jongduk Baek
IPC分类号： A61B6/00
CPC分类号： A61B6/032 , A61B6/583
摘要： A method for imaging an object in a computed tomography (CT) system with a plurality of sources comprising a first source and a second source, wherein the plurality of sources together with a detector array are mounted on a rotatable gantry, and wherein an intensity of the second source has unknown fluctuations is provided. Projection data is collected using the first source in a first gantry position. Projection data is collected using the second source in a second gantry position, wherein projection data from the first source in the first gantry position substantially overlaps projection data from the second source in the second gantry position. Data from the first source at the first gantry position is used to correct for source fluctuations of the second source at the second gantry position.
摘要翻译：一种用于在具有多个源的计算机断层摄影（CT）系统中对物体进行成像的方法，所述多个源包括第一源和第二源，其中所述多个源与检测器阵列一起安装在可旋转机架上，并且其中强度第二个来源提供了未知的波动。在第一台架位置使用第一源收集投影数据。在第二台架位置使用第二源收集投影数据，其中来自第一台架位置的第一源的投影数据在第二台架位置中基本上与来自第二源的投影数据重叠。来自第一台架位置处的第一源的数据用于校正第二机架位置处的第二源的源波动。

4. 发明授权

US07486073B2 Sliding window reconstruction and phase/field map updating for dynamic chemical shift imaging 有权
标题翻译：动态化学位移成像的滑动窗口重建和相位/场地图更新
公开(公告)号：US07486073B2
公开(公告)日：2009-02-03
申请号：US11738347
申请日：2007-04-20
申请人： Huanzhou Yu , Charles A. McKenzie , Jean H. Brittain , Norbert J. Pelc , Scott B. Reeder
发明人： Huanzhou Yu , Charles A. McKenzie , Jean H. Brittain , Norbert J. Pelc , Scott B. Reeder
IPC分类号： G01V3/00
CPC分类号： G01R33/5617 , G01R33/4828
摘要： A method for generating dynamic magnetic resonance images is provided. A cyclical magnetic resonance imaging excitation is applied for a plurality of cycles at a cycle rate. A plurality of magnetic resonance image echoes is acquired for each cycle. A plurality of frames of images is generated from the acquired plurality of magnetic resonance echoes at a frame rate that is at least twice the cycle rate, wherein each frame of the plurality of frames is generated from a plurality of echoes and wherein some of the plurality of frames are generated from magnetic resonance image echoes of adjacent cycles.
摘要翻译：提供了一种用于产生动态磁共振图像的方法。周期磁共振成像激励以循环速率施加多个周期。对于每个周期获取多个磁共振图像回波。从所获取的多个磁共振回波以至少为循环速率的两倍的帧速率产生多个图像帧，其中，多个帧中的每个帧由多个回波生成，并且其中多个帧中的一些的帧由相邻周期的磁共振图像回波产生。

5. 发明授权

US06810110B2 X-ray tube for operating in a magnetic field 失效
标题翻译：用于在磁场中操作的X射线管
公开(公告)号：US06810110B2
公开(公告)日：2004-10-26
申请号：US10306791
申请日：2002-11-27
申请人： Norbert J. Pelc , Zhifei Wen
发明人： Norbert J. Pelc , Zhifei Wen
IPC分类号： H01J3514
CPC分类号： H01J35/14 , G01R33/4812 , H01J35/16 , H05C1/02
摘要： An x-ray tube having sensors, magnets, and/or active compensation means operatively coupled thereto or integrated therein for aligning its electron beam with an external magnetic field. Permanent magnets positioned behind the anode and cathode respectively or electromagnets are used to produce a strong, properly aligned internal magnetic field. The x-ray tube is thus less sensitive to other magnetic fields that are not parallel to the anode-cathode axis. The x-ray tube can be mounted in a manner that it can pivot, allowing it to move and align itself. The x-ray tube can also be mounted such that a torque can be sensed. This sensed mechanical force is then used as an input to determine current applied to electromagnetic coils arranged to oppose a transverse magnetic field.
摘要翻译：具有传感器，磁体和/或有效补偿装置的X射线管，其可操作地耦合到其上或集成在其中，用于使其电子束与外部磁场对准。位于阳极和阴极后面的永磁体或电磁体用于产生强的适当对准的内部磁场。因此，X射线管对于不平行于阳极 - 阴极轴的其它磁场较不敏感。 X射线管可以以可枢转的方式安装，使其能够自动移动和对齐。 X射线管也可以安装成可以感测到转矩。然后将该感测到的机械力用作输入，以确定施加到布置成与横向磁场相对的电磁线圈的电流。

6. 发明授权

US5697370A Method for increasing temporal resolution of MR fluoroscopy 失效
标题翻译：增加MR荧光透视时间分辨率的方法
公开(公告)号：US5697370A
公开(公告)日：1997-12-16
申请号：US587409
申请日：1996-01-17
申请人： Norbert J. Pelc , Stephen G. Hushek
发明人： Norbert J. Pelc , Stephen G. Hushek
IPC分类号： G01R33/54 , A61B5/055 , G01R33/48 , G01R33/561 , G06T1/00
CPC分类号： G01R33/561 , G01R33/4824 , G01R33/5619
摘要： A method is described for increasing the temporal resolution of MR fluoroscopy procedures. A central portion of the image requiring a higher temporal resolution is updated more frequently using less-than-complete newly acquired NMR data. A running average of the signals produced by peripheral structures is used to form the periphery of the image and to remove artifact-producing data from the less-than-complete NMR data.
摘要翻译：描述了用于增加MR荧光透视程序的时间分辨率的方法。使用不完全的新获取的NMR数据更频繁地更新需要更高时间分辨率的图像的中心部分。由外围结构产生的信号的运行平均值用于形成图像的周边，并且从不完整的NMR数据中去除产生伪像的数据。

7. 发明授权

US5257625A Method of noninvasive motion analysis by using forced closure of phase contrast MRI maps of velocity 失效
标题翻译：通过强制关闭速度的相位对比MRI图进行无创运动分析的方法
公开(公告)号：US5257625A
公开(公告)日：1993-11-02
申请号：US865437
申请日：1992-04-09
申请人： Norbert J. Pelc
发明人： Norbert J. Pelc
IPC分类号： G01R33/561 , G01R33/563 , G01R33/567 , A61B5/055
CPC分类号： G01R33/563 , G01R33/5617 , G01R33/56316 , G01R33/5676
摘要： Measures of a velocity component during a plurality of time frames of cyclical motion of a region of interest are obtained using contrast cine MRI techniques. A position error is obtained between a known starting location and a calculated cyclical motion and is used for recalculating cyclical motion of the region of interest using the measures of velocity and the measure of error in velocity.
摘要翻译：使用对比电影MRI技术获得感兴趣区域的循环运动的多个时间帧期间的速度分量的测量。在已知的起始位置和计算的周期运动之间获得位置误差，并且用于使用速度的测量和速度误差的测量来重新计算感兴趣区域的循环运动。

8. 发明授权

US5101156A Rapid flow measurement using an NMR imaging system 失效
标题翻译：使用NMR成像系统进行快速流量测量
公开(公告)号：US5101156A
公开(公告)日：1992-03-31
申请号：US564513
申请日：1990-08-09
申请人： Norbert J. Pelc
发明人： Norbert J. Pelc
IPC分类号： A61B5/055 , G01F1/716 , G01P5/00 , G01P5/18 , G01R33/48 , G01R33/563
CPC分类号： G01R33/56308 , G01F1/716 , G01P5/00 , G01R33/56316
摘要： An NMR system measures the velocity of flowing spins in the presence of stationary spins by performing three separate measurement cycles. The first cycle is a reference, the second cycle includes a magnetic field gradient having an incremental, flow sensitizing first moment .DELTA.M.sub.1, and a third measurement cycle includes a magnetic field gradient having an incremental flow sensitizing first moment -.DELTA.M.sub.1. The resulting NMR signals are processed to produce a velocity measurement.
摘要翻译： NMR系统通过执行三个独立的测量周期来测量存在静止自旋的流动自旋速度。第一个循环是一个参考，第二个循环包括一个磁场梯度，该磁场梯度具有一个增量的流动感应初始力矩DELTA M1，而第三个测量循环包括一个具有增量流敏性第一时刻DELTA M1的磁场梯度。对所得NMR信号进行处理以产生速度测量。

9. 发明授权

US5051903A Method and apparatus for predicting values of a varying periodic phenomenon 失效
标题翻译：用于预测变化周期性现象的值的方法和装置
公开(公告)号：US5051903A
公开(公告)日：1991-09-24
申请号：US393376
申请日：1989-08-14
申请人： Norbert J. Pelc , Stephen W. Flax
发明人： Norbert J. Pelc , Stephen W. Flax
IPC分类号： G01R33/54 , A61B5/055 , G01R33/32 , G01R33/567 , G06F17/18
CPC分类号： G01R33/5673
摘要： An apparatus for reducing image artifacts in NMR imaging matches elements of a set to values of a substantially periodic function so that the values exhibit a predetermined relationship to the elements. The matching is performed by evaluating the relative probability of the values of the substantially periodic function from the samples in the growing database of the values and assigning the values to the elements by using the evaluated relative probability, so as to maximize the probability that subsequent valves may be assigned the remaining elements according the predetermined relationship. A method for correcting the matching of values with elements freezes the database and acquires additional values which are substituted for earlier matched values based on the frozen database.

10. 发明授权

US5005419A Method and apparatus for coherent imaging system 失效
标题翻译：相干成像系统的方法和装置
公开(公告)号：US5005419A
公开(公告)日：1991-04-09
申请号：US207532
申请日：1988-06-16
申请人： Matthew O'Donnell , Kenneth B. Welles, II , Carl R. Crawford , Norbert J. Pelc , Steven G. Karr
发明人： Matthew O'Donnell , Kenneth B. Welles, II , Carl R. Crawford , Norbert J. Pelc , Steven G. Karr
IPC分类号： A61B8/00 , G01N29/06 , G01S7/52 , G01S7/526 , G01S15/89 , G06T1/00
CPC分类号： G01S7/52023 , G01S15/8915
摘要： A method and apparatus for improved digital processing of the analog echo signals in a coherent imaging system is described which simplifies the channel circuitry requirements. The analog echo signals detected with a phased array of transducer elements are first compressed in a non-linear manner then expanded non-linearly with analog-to-digital converter means to provide increased instantaneous dynamic range in the overall system. Representative phased array coherent imaging systems having the improved digital processing means are also disclosed.
摘要翻译：描述了一种用于改进相干成像系统中的模拟回波信号的数字处理的方法和装置，其简化了信道电路要求。用相控阵的换能器元件检测的模拟回波信号首先以非线性方式压缩，然后以模数转换器装置非线性地扩展，以在整个系统中提供增加的瞬时动态范围。还公开了具有改进的数字处理装置的代表性相控阵相干成像系统。

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