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1. 发明授权

US5217699A Calcium-phosphate type hydroxyapatite 失效
标题翻译：磷酸钙型羟基磷灰石
公开(公告)号：US5217699A
公开(公告)日：1993-06-08
申请号：US731567
申请日：1991-07-17
申请人： Nobuaki Tagaya , Hideyuki Kuwakara , Takao Hashimoto , Noriko Komatsu , Keiko Fukamachi , Tsugio Maeshima , Toshihiro Ishikawa , Tetsuro Ogawa
发明人： Nobuaki Tagaya , Hideyuki Kuwakara , Takao Hashimoto , Noriko Komatsu , Keiko Fukamachi , Tsugio Maeshima , Toshihiro Ishikawa , Tetsuro Ogawa
IPC分类号： B01J20/04 , C01B25/32
CPC分类号： B01J20/282 , B01J20/048 , C01B25/32 , C01B25/322 , B01J2220/54
摘要： A calcium-phosphate type hydroxyapatite for chromatographic separation is in the form of spherulites having a mean particle diameter of 0.5 to 50 .mu.m, preferably 1 to 10 .mu.m. The spherulites are each an aggregate mainly of acicular crystallites belonging to a series of hexagonal systems and having unit lattice constants of 9.58.+-.0.08 .ANG. for the a axis and 7.00.+-.0.05 .ANG. for the c axis. The hydroxyapatite is produced by granulating a calcium=phosphate type hydroxyapatite in the form of a gel and then firing the granular apatite at 400.degree. to 700.degree. C., preferably at 500.degree. to 600.degree. C. The firing is performed by heating the granules in the presence of oxygen or air for a given period of time.
摘要翻译：用于色谱分离的磷酸钙型羟基磷灰石为平均粒径为0.5〜50μm，优选为1〜10μm的球晶。球晶各自是主要由属于一系列六边形系统的针状微晶组成，并且具有针对轴的单位晶格常数为9.58 +/- 0.08安格姆和c轴的7.00 +/- 0.05安培角。羟基磷灰石是通过将凝胶形式的钙=磷酸酯型羟基磷灰石制粒，然后在400〜700℃，优选在500〜600℃下烧成粒状磷灰石制造的。烧成是通过加热颗粒在氧气或空气的存在下给定一段时间。

2. 发明授权

US5082566A Calcium-phosphate type hydroxyapatite for chromatographic separation and process for producing same 失效
标题翻译：用于色谱分离的磷酸钙型羟基磷酸酯及其生产方法
公开(公告)号：US5082566A
公开(公告)日：1992-01-21
申请号：US243550
申请日：1988-09-12
申请人： Nobuaki Tagaya , Hideyuki Kuwahara , Takao Hashimoto , Noriko Komatsu , Keiko Fukamachi , Tsugio Maeshima , Toshihiro Ishikawa , Tetsuro Ogawa
发明人： Nobuaki Tagaya , Hideyuki Kuwahara , Takao Hashimoto , Noriko Komatsu , Keiko Fukamachi , Tsugio Maeshima , Toshihiro Ishikawa , Tetsuro Ogawa
IPC分类号： B01J20/281 , B01J20/04 , B01J20/28 , C01B25/32 , G01N30/88
CPC分类号： B01J20/048 , B01J20/282 , C01B25/32 , C01B25/322 , B01J2220/54
摘要： A calcium-phosphate type hydroxyapatite for chromatographic separation is in the form of spherulites having a mean particle diameter of 0.5 to 50 .mu.m, preferably 1 to 10 .mu.m. The spherulites are each an aggregate mainly of acicular crystallites belonging to a series of hexagonal systems and having unit lattice constants of 9.58.+-.0.08 .ANG. for the a axis and 7.00.+-.0.05 .ANG. for the c axis. The hydroxyapatite is produced by granulating a calcium-phosphate type hydroxyapatite in the form of a gel and then firing the granular apatite at 400.degree. to 700.degree. C., preferably at 500.degree. to 600.degree. C. The firing is performed by heating the granules in the presence of oxygen or air for a given period of time.

3. 发明授权

US4781904A Calcium-phosphate type hydroxyapatite for chromatographic separation and process for producing same 失效
标题翻译：磷酸钙型羟基磷灰石用于色谱分离及其制备方法
公开(公告)号：US4781904A
公开(公告)日：1988-11-01
申请号：US909978
申请日：1986-09-22
申请人： Nobuaki Tagaya , Hideyuki Kuwahara , Takao Hashimoto , Noriko Komatsu , Keiko Fukamachi , Tsugio Maeshima , Toshihiro Ishikawa , Tetsuro Ogawa
发明人： Nobuaki Tagaya , Hideyuki Kuwahara , Takao Hashimoto , Noriko Komatsu , Keiko Fukamachi , Tsugio Maeshima , Toshihiro Ishikawa , Tetsuro Ogawa
IPC分类号： B01J20/281 , B01J20/04 , B01J20/28 , C01B25/32 , G01N30/88
CPC分类号： B01J20/048 , B01J20/282 , C01B25/32 , C01B25/322 , B01J2220/54
摘要： A calcium-phosphate type hydroxyapatite for chromatographic separation is in the form of spherulites having a mean particle diameter of 0.5 to 50 .mu.m, preferably 1 to 10 .mu.m. The spherulites are each an aggregate mainly of acicular crystallites belonging to a series of hexagonal systems and having unit lattice constants of 9.58.+-.0.08 .ANG. for the a axis and 7.00.+-.0.05 .ANG. for the c axis. The hydroxyapatite is produced by granulating a calcium-phosphate type hydroxyapatite in the form of a gel and then firing the granular apatite at 400.degree. to 700.degree. C., preferably at 500.degree. to 600.degree. C. The firing is performed by heating the granules in the presence of oxygen or air for a given period of time.
摘要翻译：用于色谱分离的磷酸钙型羟基磷灰石为平均粒径为0.5〜50μm，优选为1〜10μm的球晶。球晶各自是主要由属于一系列六边形系统的针状微晶组成，并且具有针对轴的单位晶格常数为9.58 +/- 0.08安格姆和c轴的7.00 +/- 0.05安培角。羟基磷灰石是通过将凝胶形式的磷酸钙型羟基磷灰石制粒，然后在400〜700℃，优选在500〜600℃下烧成粒状磷灰石制造的。烧成是通过加热颗粒在氧气或空气的存在下给定一段时间。

4. 发明申请

US20110280943A1 Sunscreen Compositions Comprising Uniform, Rigid, Spherical, Nanoporous Calcium Phosphate Particles and Methods of Making and Using the Same 有权
标题翻译：包含均匀，刚性，球形，纳米孔磷酸钙颗粒的防晒组合物及其制备和使用方法
公开(公告)号：US20110280943A1
公开(公告)日：2011-11-17
申请号：US12943887
申请日：2010-11-10
申请人： Zahra Mansouri , Rodica-Tatiana Canelide , Douglas Thomas , Tetsuro Ogawa
发明人： Zahra Mansouri , Rodica-Tatiana Canelide , Douglas Thomas , Tetsuro Ogawa
IPC分类号： A61K8/06 , A61Q17/04
CPC分类号： A61K8/025 , A61K8/0279 , A61K8/24 , A61K8/27 , A61K8/29 , A61K8/37 , A61K8/40 , A61K2800/412 , A61K2800/56 , A61K2800/5922 , A61K2800/60 , A61Q17/04
摘要： Aspects of the invention include sunscreen formulations that include uniform, rigid, spherical nanoporous calcium phosphate particles. Also provided are methods of making the sunscreen formulations. The sunscreen formulations find use in sunblocking applications.
摘要翻译：本发明的方面包括防晒制剂，其包括均匀的刚性球形纳米多孔磷酸钙颗粒。还提供制备防晒制剂的方法。防晒霜配方可用于遮阳用途。

5. 发明授权

US5827669A Sheets, kits and methods for detecting antigens or antibodies 失效
标题翻译：用于检测抗原或抗体的片剂，试剂盒和方法
公开(公告)号：US5827669A
公开(公告)日：1998-10-27
申请号：US746485
申请日：1996-11-12
申请人： Mikio Nakayama , Tadahiko Kitano , Ayumi Mitoh , Tetsuro Ogawa , Tsuneo Hiraide
发明人： Mikio Nakayama , Tadahiko Kitano , Ayumi Mitoh , Tetsuro Ogawa , Tsuneo Hiraide
IPC分类号： G01N33/53 , G01N33/543 , G01N33/547 , G01N33/551
CPC分类号： G01N33/54306 , G01N33/54313 , Y10S435/969 , Y10S435/97 , Y10S435/975 , Y10S436/808
摘要： A detection sheet capable of detecting an antigen or antibody in a biological fluid with a high sensitivity in a simple operation, as well as a detection kit and detection method using the detection sheet. The detection sheet comprises (a) a fibrous aggregate with carried particles of a calcium phosphate compound having an average particle diameter of about 0.01 to 200 microns and a Ca/P ratio of about 1.0 to 2.0, and (b) an avidin, streptavidin or avidin derivative from which carbohydrates have been extracted immobilized on said calcium phosphate compound. After a biotinylated antigen or antibody is bonded to the immobilized avidin, streptavidin, or avidin derivative of the detection sheet, the detection sheet is contacted with a test solution to thereby bond an antigen or antibody of the test solution to the detection sheet. The detection sheet is then contacted with a solution of labeling compound capable of being specifically bonded to the antigen or antibody of said test solution to detect the thus labeled antigen-antibody complex.
摘要翻译：能够在简单的操作中能够以高灵敏度检测生物流体中的抗原或抗体的检测片以及使用检测片的检测试剂盒和检测方法。检测片包括（a）具有平均粒径为约0.01至200微米并且Ca / P比为约1.0至2.0的带有磷酸钙化合物的载体的纤维聚集体，和（b）抗生物素蛋白，链霉抗生物素蛋白或提取固定在所述磷酸钙化合物上的碳水化合物的抗生物素蛋白衍生物。将生物素化的抗原或抗体与检测片的固定化抗生物素蛋白，链亲和素或抗生物蛋白衍生物结合后，使检测片与测试溶液接触，从而将检测溶液的抗原或抗体与检测片结合。然后将检测片与能够与所述测试溶液的抗原或抗体特异性结合的标记化合物溶液接触，以检测如此标记的抗原 - 抗体复合物。

6. 发明授权

US5310548A Deodorants, deodorant sheets, filter sheets and functional papers as well as filtering mediums for exhaust gas 失效
标题翻译：除臭剂，除臭片，滤纸和功能纸以及废气过滤介质
公开(公告)号：US5310548A
公开(公告)日：1994-05-10
申请号：US840586
申请日：1992-02-26
申请人： Sumiaki Tsuru , Akihiko Yokoo , Takeshi Sakurai , Tetsuro Ogawa
发明人： Sumiaki Tsuru , Akihiko Yokoo , Takeshi Sakurai , Tetsuro Ogawa
IPC分类号： A61L9/01 , B01D39/08 , B01D53/02 , B01D53/04 , B01D53/58 , B01D53/92 , B01J20/04
CPC分类号： A61L9/01 , B01D39/086 , B01D53/02 , B01D53/0415 , B01D53/58 , B01D53/922 , B01J20/048 , B01J20/22 , B01J20/28004 , B01J20/28054 , B01J20/28059 , B01J20/3208 , B01J20/3236 , B01D2239/0407 , B01D2239/045 , B01D2239/0457 , B01D2239/0464 , B01D2239/0471 , B01D2239/0618 , B01D2239/0654 , B01D2239/1208 , B01D2239/1241 , B01D2251/404 , B01D2251/61 , B01D2253/104 , B01D2253/106 , B01D2253/108 , B01D2253/25 , B01D2253/304 , B01D2253/308 , B01D2253/311 , B01D2253/342 , B01D2257/502 , B01D2257/702 , B01D2257/90 , B01D2257/91 , B01D2257/93 , B01D2259/4566 , B01D53/0446 , B01J2220/4831 , Y10S55/05 , Y10S55/30
摘要： Deodorant comprising 5 to 100% by weight of a calcium phosphate compound having a molar ratio of Ca/P of 0.8 to 2.0, a deodorant sheet and filter sheet containing such calcium phosphate compound, and a functional paper containing 10 to 80% by weight of a calcium phosphate compound. A filtering medium for an exhaust gas comprises a ceramic material containing 5 to 100% by weight of a calcium phosphate compound, as well as a filter cartridge and exhaust gas filter containing the filtering medium. Based on the excellent properties of the incorporated calcium phosphate compound, the agents and products according to the present invention exhibit a highly improved adsorptivity to oil-soluble substances, odor substances, animal or vegetable cells, viruses, biopolymeric substances or other substances, and therefore can be advantageously used in various fields of technology. For example, the functional paper can be used as a deodorant, filter medium and adsorbent as well as a flame-retardant paper. The filtering medium, filter cartridge and filter can be used in an exhaust system to purify an exhaust gas produced therein.
摘要翻译：包含5至100重量％的Ca / P摩尔比为0.8至2.0的磷酸钙化合物，除臭剂片和含有这种磷酸钙化合物的滤片以及含有10至80重量％的磷酸钙化合物的功能性纸的除臭剂一种磷酸钙化合物。用于排气的过滤介质包括含有5至100重量％的磷酸钙化合物的陶瓷材料，以及包含过滤介质的过滤器滤芯和废气过滤器。基于掺入的磷酸钙化合物的优异性质，根据本发明的试剂和产品显示出对油溶性物质，气味物质，动植物细胞，病毒，生物聚合物或其它物质的吸附性的高度改善，因此可以有利地用于各种技术领域。例如，功能纸可以用作除臭剂，过滤介质和吸附剂以及阻燃纸。过滤介质，滤筒和过滤器可用于排气系统中以净化其中产生的废气。

7. 发明授权

US5240659A Process for producing shaped article of oriented calcium phosphate type compound 失效
标题翻译：用于生产定向磷酸钙型化合物成型制品的方法
公开(公告)号：US5240659A
公开(公告)日：1993-08-31
申请号：US857638
申请日：1992-03-24
申请人： Takeshi Ichitsuka , Tetsuro Ogawa , Masaya Sumita , Akihiko Yokoo
发明人： Takeshi Ichitsuka , Tetsuro Ogawa , Masaya Sumita , Akihiko Yokoo
IPC分类号： A61F2/00 , A61L27/12 , C04B35/447 , C04B35/634
CPC分类号： C04B35/447 , A61L27/12 , C04B35/634 , A61F2310/00293
摘要： An oriented shaped article of a calcium phosphate type compound is disclosed, in which at least two crystallographic axes of the primary particles of which the shaped article is composed each is oriented in one direction, respectively, in at least the surface of said article. A sinter of the oriented shaped article and a processes for producing the article and the sinter are also disclosed.
摘要翻译：公开了一种磷酸钙型化合物的取向成型制品，其中至少两个成型制品的一次颗粒的结晶轴分别在至少所述制品的表面上沿一个方向取向。还公开了定向成型制品的烧结体以及制造制品和烧结体的方法。

8. 发明授权

US5017518A Process for producing calcium phosphate ceramics having porous surface 失效
标题翻译：具有多孔表面的磷酸钙陶瓷的制造方法
公开(公告)号：US5017518A
公开(公告)日：1991-05-21
申请号：US511814
申请日：1990-04-18
申请人： Yasuhiko Hirayama , Tetsuro Ogawa , Satoshi Ojima
发明人： Yasuhiko Hirayama , Tetsuro Ogawa , Satoshi Ojima
IPC分类号： C04B38/00 , A61F2/00 , A61K6/033 , A61L27/00 , A61L27/12 , B01J20/04 , C04B35/447 , C04B38/04 , C04B41/53 , C04B41/91
CPC分类号： C04B35/447 , A61K6/0044 , A61K6/0085 , A61K6/0643 , A61L27/12 , B01J20/048 , B01J20/28078 , B01J20/3078 , B01J20/3085 , C04B38/04 , C04B41/009 , C04B41/5353 , C04B41/91 , A61F2310/00293
摘要： A process for producing calcium phosphate ceramics having a porous surface is described, which comprise the steps of:a) preparing untreated calcium phosphate ceramics, which comprises a mixture of hydroxyapatite and tricalcium phosphate, andb) treating said untreated ceramics with an acidic solution to selectively dissolve the tricalcium phosphate in the surface of the ceramics.
摘要翻译：描述了一种生产具有多孔表面的磷酸钙陶瓷的方法，其包括以下步骤：a）制备包括羟基磷灰石和磷酸三钙的混合物的未处理的磷酸钙陶瓷，和b）用酸性溶液处理所述未处理的陶瓷，选择性地将磷酸三钙溶解在陶瓷表面。

9. 发明授权

US4663630A PPI radar apparatus 失效
标题翻译： PPI雷达设备
公开(公告)号：US4663630A
公开(公告)日：1987-05-05
申请号：US550218
申请日：1983-11-09
申请人： Yoshio Numaho , Yoshio Kato , Tetsuro Ogawa , Hiroshi Okada , Kiyoshi Arima
发明人： Yoshio Numaho , Yoshio Kato , Tetsuro Ogawa , Hiroshi Okada , Kiyoshi Arima
IPC分类号： G01S7/06 , G01S7/12
CPC分类号： G01S7/12 , G01S7/068
摘要： A PPI radar apparatus is constructed such that even when a transmission time cycle of radio waves is varied by switchover of a distance range to any of short, middle and long distance ranges, a sweep display time cycle of a radar video signal received in any of the distance ranges is maintained constant at all times; the sweep display time cycle is determined to meet the middle distance ranges, in the short distance ranges in which the reception time of radio waves is short, the video signals are written in storage means in real-time and then displayed by readout of the video signals at a low speed in synchronism with the sweep time cycle, in the long distance ranges in which the reception time of radio waves is long, the video signals are written in storage means in real-time and then displayed by a number of readouts in one sweep display time cycle; and the video signals written in a plurality of storage means are parallelly read out and a mean value or peak of the read-out video signals is obtained by arithmetic operation to thereby enhance the signal-to-noise ratio of the radar image.
摘要翻译： PPI雷达装置被构造成即使当通过将距离范围切换到短距离，中距离和长距离范围中的任何一个来改变无线电波的传输时间周期时，在任何一个中接收的雷达视频信号的扫描显示时间周期距离范围始终保持不变; 扫描显示时间周期被确定为满足中间距离范围，在无线电波的接收时间短的短距离范围内，视频信号被实时地写入存储装置，然后通过读出视频显示与扫描时间周期同步地以低速信号，在无线电波的接收时间长的长距离范围内，视频信号被实时地写入存储装置，然后通过多个读出显示在一次扫描显示时间周期; 写入多个存储装置的视频信号并行读出，通过算术运算获得读出的视频信号的平均值或峰值，从而提高雷达图像的信噪比。

10. 发明申请

US20050079226A1 CaO-MgO-SiO2-based bioactive glass and sintered calcium phosphate glass using same 失效
标题翻译： CaO-MgO-SiO2基生物活性玻璃和使用其的烧结磷酸钙玻璃
公开(公告)号：US20050079226A1
公开(公告)日：2005-04-14
申请号：US10962557
申请日：2004-10-13
申请人： Yukiko Gonda , Tetsuro Ogawa , Tadashi Kokubo
发明人： Yukiko Gonda , Tetsuro Ogawa , Tadashi Kokubo
IPC分类号： A61L27/00 , A61F2/28 , A61F2/30 , A61K6/027 , A61K6/06 , A61L27/10 , A61L27/12 , C03C3/112 , C03C4/00 , C03C10/04 , C03C10/16 , C04B35/447 , C03C3/105 , A61K33/42
CPC分类号： A61L27/10 , A61L27/12 , C03C3/112 , C03C4/0007 , C03C10/16
摘要： A bioactive glass having a composition substantially comprising 20 to 40 mol % of CaO, 40 to 60 mol % of SiO2, and 10 to 20 mol % of MgO is high in bioactivity and mechanical strength, and a sintered calcium phosphate glass using the bioactive glass as a sintering aid is excellent in biocompatibility and mechanical strength.
摘要翻译：具有基本上包含20-40摩尔％CaO，40-60摩尔％SiO 2和10-20摩尔％MgO的组成的生物活性玻璃具有高生物活性和机械强度，并且使用生物活性玻璃的磷酸钙烧结烧结玻璃作为烧结助剂，生物相容性和机械强度优异。

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