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1. 发明申请

US20090138000A1 Cryosurgical devices and methods for endometrial ablation 审中-公开
公开(公告)号：US20090138000A1
公开(公告)日：2009-05-28
申请号：US12321818
申请日：2009-01-26
申请人： David W. Vancelette , NICHOLAS R. Van der Walt , Jia Hua Xiao , Eva S. Snitkin
发明人： David W. Vancelette , NICHOLAS R. Van der Walt , Jia Hua Xiao , Eva S. Snitkin
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2017/4216 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262
摘要： A cryoablation system including a cannula having a proximal end, a distal end, and a longitudinal axis, an expandable balloon extending from the distal end of the cannula and fluidly connected to a source of heat transfer fluid by at least one fluid path, a pump for circulating the heat transfer fluid into and out of the balloon, a probe handle coupled to the proximal end of the cannula and in fluidic communication with the balloon through the cannula, and a heat exchanger for varying the temperature of the heat transfer fluid, wherein the heat exchanger is fluidly connected to a secondary refrigerant source. The heat exchanger may be positioned within the probe handle, within the cannula, or at least partially within the balloon. The heat transfer fluid of this cryoablation system preferably has a freezing point lower than about −110° C. and a boiling point greater than about 50° C.

2. 发明授权

US07381208B2 Cryosurgical devices for endometrial ablation 有权
标题翻译：用于子宫内膜消融的冷冻手术器械
公开(公告)号：US07381208B2
公开(公告)日：2008-06-03
申请号：US11020792
申请日：2004-12-22
申请人： Nicholas R. van der Walt , Jia Hua Xiao , David W. Vancelette
发明人： Nicholas R. van der Walt , Jia Hua Xiao , David W. Vancelette
IPC分类号： A61B18/18
CPC分类号： A61B18/02 , A61B2017/4216 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262
摘要： A cryoablation system for performing endometrial ablation comprising an elongated tubular cannula having a proximal end, a distal end, and a longitudinal axis, an expandable balloon extending from the distal end of the cannula and fluidly connected to a source of heat transfer fluid by at least one fluid path, a pump for circulating the heat transfer fluid into and out of the balloon, a probe handle coupled to the proximal end of the cannula and in fluidic communication with the balloon through the cannula, and a heat exchanger for varying the temperature of the heat transfer fluid, wherein the heat exchanger is fluidly connected to a secondary refrigerant source, and wherein the heat exchanger comprises an outer tubular wall and a plurality of fins extending from the tubular wall toward the interior portion of the heat exchanger.
摘要翻译：一种用于进行子宫内膜消融的冷冻消融系统，包括具有近端，远端和纵向轴线的细长管状插管，从套管的远端延伸并且至少流体连接到传热流体源的可膨胀气囊一个流体路径，用于将传热流体循环到气囊中的泵;耦合到套管的近端并通过插管与气囊流体连通的探针手柄，以及用于改变温度的热交换器所述传热流体，其中所述热交换器流体地连接到二次制冷剂源，并且其中所述热交换器包括外部管状壁和从所述管状壁朝向所述热交换器的内部延伸的多个翅片。

3. 发明授权

US07500973B2 Cryosurgical devices and methods for endometrial ablation 失效
标题翻译：用于子宫内膜消融的冷冻手术装置和方法
公开(公告)号：US07500973B2
公开(公告)日：2009-03-10
申请号：US11020791
申请日：2004-12-22
申请人： David W. Vancelette , Nicholas R. van der Walt , Jia Hua Xiao , Eva S. Snitkin
发明人： David W. Vancelette , Nicholas R. van der Walt , Jia Hua Xiao , Eva S. Snitkin
IPC分类号： A61B18/18
CPC分类号： A61B18/02 , A61B2017/4216 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262
摘要： A cryoablation system including a cannula having a proximal end, a distal end, and a longitudinal axis, an expandable balloon extending from the distal end of the cannula and fluidly connected to a source of heat transfer fluid by at least one fluid path, a pump for circulating the heat transfer fluid into and out of the balloon, a probe handle coupled to the proximal end of the cannula and in fluidic communication with the balloon through the cannula, and a heat exchanger for varying the temperature of the heat transfer fluid, wherein the heat exchanger is fluidly connected to a secondary refrigerant source. The heat exchanger may be positioned within the probe handle, within the cannula, or at least partially within the balloon. The heat transfer fluid of this cryoablation system preferably has a freezing point lower than about −110° C. and a boiling point greater than about 50° C.
摘要翻译：一种冷冻消融系统，包括具有近端，远端和纵向轴线的插管，从套管的远端延伸并且通过至少一个流体路径流体连接到传热流体源的可膨胀气囊，泵用于使所述传热流体循环到所述球囊中;探针手柄，其耦合到所述套管的近端并通过所述套管与所述球囊流体连通;以及热交换器，用于改变所述传热流体的温度，其中热交换器流体地连接到二次制冷剂源。热交换器可以位于探针手柄内，套管内，或者至少部分地位于气囊内。该冷冻消融系统的传热流体优选具有低于约-110℃的凝固点和大于约50℃的沸点。

4. 发明申请

US20080027420A1 Cryosurgical Imaging and Monitoring Systems 审中-公开
标题翻译：冷冻成像和监测系统
公开(公告)号：US20080027420A1
公开(公告)日：2008-01-31
申请号：US11828095
申请日：2007-07-25
申请人： Ling Wang , Jia Hua Xiao , Douglas A. Devens , David W. Vancelette
发明人： Ling Wang , Jia Hua Xiao , Douglas A. Devens , David W. Vancelette
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B34/10 , A61B90/37 , A61B2017/00101
摘要： Improved imaging and monitoring systems for use with a closed loop cryosurgical system. As described herein, various systems can be used alone or in conjunction with one another to plan and/or monitor cryosurgical procedures in order to improve cryosurgical outcomes. These systems can include computer assisted planning systems, non-ultrasound based imaging systems and temperature monitoring systems utilized individually or in combination. Through the use of these systems, the precision by which cryosurgical procedures are performed are enhanced.
摘要翻译：改进的成像和监测系统用于闭环冷冻手术系统。如本文所述，各种系统可以单独使用或者彼此结合使用来规划和/或监测冷冻手术程序，以便改善冷冻手术的结果。这些系统可以包括计算机辅助计划系统，基于非超声的成像系统和单独或组合使用的温度监测系统。通过使用这些系统，提高了执行冷冻手术的精度。

5. 发明授权

US08157722B2 Surgical implants and related methods and systems 有权
标题翻译：手术植入物及相关方法和系统
公开(公告)号：US08157722B2
公开(公告)日：2012-04-17
申请号：US12772592
申请日：2010-05-03
申请人： Kevin R. Arnal , Sidney F. Hauschild , Robert E. Lund , Suranjan Roychowdhury , David W. Vancelette
发明人： Kevin R. Arnal , Sidney F. Hauschild , Robert E. Lund , Suranjan Roychowdhury , David W. Vancelette
IPC分类号： A61F2/00
CPC分类号： A61F2/0063 , A61B17/06066 , A61B17/06109 , A61B2017/0046 , A61B2017/00805 , A61B2017/06076 , A61F2/0045 , A61F2250/0078 , Y10T29/49 , Y10T29/49885
摘要： Described are surgical implants, tools, systems, and related methods, useful for implantation of surgical implants, such as those used to treat pelvic conditions including incontinence.
摘要翻译：描述了可用于植入外科植入物的外科植入物，工具，系统和相关方法，例如用于治疗包括失禁的骨盆病症的手术植入物。

6. 发明申请

US20080119839A1 Cryosurgical Applicator 审中-公开
标题翻译：冷冻敷贴器
公开(公告)号：US20080119839A1
公开(公告)日：2008-05-22
申请号：US11943711
申请日：2007-11-21
申请人： David W. Vancelette
发明人： David W. Vancelette
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2018/0231 , A61B2018/0262
摘要： A cordless cryosurgical applicator system having a base unit and one or more rechargeable cryosurgical applicators. The base unit can be use to charge the applicator with a cryogenic fluid such that a cryosurgical procedure can be performed. Following use of the applicator, the applicator can be recharged by attaching the applicator to the base unit and refilling a cryogenic reservoir in the applicator from a cryogenic storage tank contained within the base unit. The base unit can include a self-contained assembly for generating a cryogenic fluid such that the cordless cryosurgical applicator system is essentially self-sufficient when attached to an electrical power source.
摘要翻译：一种无绳式冷冻手术施放器系统，其具有基座单元和一个或多个可再次冷冻手术施放器。基本单元可用于向低温液体的给药器充电，从而可以进行冷冻手术。在使用施加器之后，可以通过将施加器附接到基座单元并且从包含在基座单元内的低温储存罐在施料器中重新填充低温储存器来对施加器进行再充电。基座单元可以包括用于产生低温流体的独立组件，使得当连接到电源时无绳式冷冻手术施放器系统基本上是自给自足的。

7. 发明申请

US20080110182A1 Coaxial Cryogenic Refrigeration Coupler 审中-公开
标题翻译：同轴低温制冷耦合器
公开(公告)号：US20080110182A1
公开(公告)日：2008-05-15
申请号：US11938352
申请日：2007-11-12
申请人： David W. Vancelette , Patricia M. Derus
发明人： David W. Vancelette , Patricia M. Derus
IPC分类号： F17C13/00
CPC分类号： A61B18/02 , A61B2017/00199 , A61B2017/00477 , A61B2018/0262 , A61B2018/0293
摘要： A cryosurgical system having a coupler for connecting a disposable cryoprobe end portion to a non-disposable cryoprobe base portion. A cryoprobe can include a disposable portion that connects via a coupler to a non-disposable portion that is permanently attached to the cryosurgical system. Once a disposable portion is attached to the cryosurgical system, refrigerant can be circulated through the system and a cryothermal treatment can be performed. Upon completion of the cryosurgical treatment, the disposable portion can be detached and discarded.
摘要翻译：一种冷冻手术系统，具有用于将一次性冷冻探针端部连接到非一次性冷冻探针基部的耦合器。冷冻探针可以包括通过耦合器连接到永久地附接到冷冻手术系统的非一次性部分的一次性部分。一旦将一次性部分连接到冷冻手术系统，制冷剂可以循环通过系统并且可以进行低温治疗。在完成冷冻治疗后，一次性部分可以分离和丢弃。

8. 发明申请

US20080119840A1 Ridged Cryoprobe Tip 审中-公开
标题翻译：脊髓冷冻保护尖
公开(公告)号：US20080119840A1
公开(公告)日：2008-05-22
申请号：US11943777
申请日：2007-11-21
申请人： David W. Vancelette , Michael W.V. Perkins
发明人： David W. Vancelette , Michael W.V. Perkins
IPC分类号： A61B18/18
CPC分类号： A61B18/02 , A61B2018/0262
摘要： A cryoprobe for use in a cryosurgical system in which the probe tip has an increased surface area by having a corrugated, waved, or otherwise ridged configuration in its inner and outer surfaces. The increased surface area functions to provide greater surface area on the probe tip, and thus greater heat transfer, between the refrigerant and inner surface of the cryoprobe and between the outer surface of the cryoprobe and the target tissue.
摘要翻译：一种用于冷冻手术系统的冷冻探针，其中探针尖端通过在其内表面和外表面中具有波纹状，波浪形或其它方式构造而具有增加的表面积。增加的表面积用于在探针尖端上提供更大的表面积，从而在制冷剂和冷冻探针的内表面之间以及冷冻探针的外表面与靶组织之间更大的热传递。

9. 发明申请

US20080119833A1 Cryoprobe with Heating and Temperature Sensing Capabilities 审中-公开
标题翻译：带加热和温度检测功能的冷冻探头
公开(公告)号：US20080119833A1
公开(公告)日：2008-05-22
申请号：US11940485
申请日：2007-11-15
申请人： David W. Vancelette , Randall C. Lieser
发明人： David W. Vancelette , Randall C. Lieser
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2017/00084 , A61B2018/00041 , A61B2018/0262
摘要： The present disclosure is directed to a cryoprobe including heating capabilities within the cryoprobe tip for use in a cryosurgical system. A heating element can be operably secured to an inner surface of the cryoprobe tips, wherein the heating element can then be connected to an electrical current source such that heat is generated at the cryoprobe tip as the electrical current flows through the heating element. In one version, the heating element can comprise a resistive element laminated between layers of insulation while in other, alternative versions, the heating element can comprise a small diameter resistance wire attached directly to an inner surface within the cryoprobe tip. The cryoprobe can include a thermocouple secured within the cryoprobe tip so as to take temperature measurements during both freezing and thawing cycles. In some versions, the heating element can be operably secured within the cryoprobe tip using an expanding or rotating mandrel.
摘要翻译：本公开涉及一种包括冷冻探针末端内的用于冷冻手术系统的加热能力的冷冻探针。加热元件可以可操作地固定到冷冻探针尖端的内表面，其中然后可以将加热元件连接到电流源，使得当电流流过加热元件时，在冷冻探针末端产生热量。在一个版本中，加热元件可以包括层压在绝缘层之间的电阻元件，而在其它替代形式中，加热元件可以包括直接附接到冷冻探针尖端内的内表面的小直径电阻丝。冷冻探针可以包括固定在冷冻探针末端内的热电偶，以便在冷冻和解冻循环期间进行温度测量。在一些形式中，加热元件可以使用扩张或旋转的心轴可操作地固定在冷冻探针尖端内。

10. 发明申请

US20080115509A1 Methods and Apparatus for Forming and Connecting Cryoprobes for use with Cryosurgical Treatment Systems 审中-公开
标题翻译：用于冷冻保存治疗系统使用的冷冻保存方法和装置
公开(公告)号：US20080115509A1
公开(公告)日：2008-05-22
申请号：US11942029
申请日：2007-11-19
申请人： Adam L. Gullickson , Douglas A. Devens , David W. Vancelette , Michael W.V. Perkins , Randall C. Lieser
发明人： Adam L. Gullickson , Douglas A. Devens , David W. Vancelette , Michael W.V. Perkins , Randall C. Lieser
IPC分类号： F17C13/00 , A61B18/02
CPC分类号： A61B18/02 , A61B2018/0231
摘要： Methods and apparatus for connecting disposable and non-disposable portions of a cryoprobe for use with a cryosurgical treatment system. Representative cryoprobes can include a disposable and non-disposable portion joined with a connector such as a coupler for connecting a single disposable portion to a single non-disposable portion. A representative coupler can include coupler ports into which connecting ends of fluid delivery tubes within the disposable and non-disposable portions can fluidly connect. A manifold mounting plate can include a plurality of slots into which disposable portions can be fluidly interconnected to non-disposable portions.
摘要翻译：用于连接用于冷冻手术治疗系统的冷冻探针的一次性和非一次性部分的方法和装置。代表性的冷冻探针可以包括与诸如耦合器的连接器连接的一次性和非一次性部分，用于将单个一次性部分连接到单个非一次性部分。代表性的联接器可以包括耦合器端口，一次性和非一次性部分内的流体输送管的连接端可以流体地连接到该联接器端口中。歧管安装板可以包括多个狭槽，一次性部分可以流体地互连到非一次性部分。

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