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1. 发明授权

US08067640B2 Method for the separation of intermediates which may be used for the preparation of escitalopram 失效
标题翻译：用于分离可用于制备依他普仑的中间体的方法
公开(公告)号：US08067640B2
公开(公告)日：2011-11-29
申请号：US12781026
申请日：2010-05-17
申请人： Naoki Taoka , Takahisa Kato , Shogo Yamamoto , Takashi Yoshida , Toshihiro Takeda , Yasuyoshi Ueda , Hans Petersen , Robert Dancer , Haleh Ahmadian , Lars O. Lyngso
发明人： Naoki Taoka , Takahisa Kato , Shogo Yamamoto , Takashi Yoshida , Toshihiro Takeda , Yasuyoshi Ueda , Hans Petersen , Robert Dancer , Haleh Ahmadian , Lars O. Lyngso
IPC分类号： C07C57/00
CPC分类号： C07B57/00 , C07B2200/07 , C07C253/30 , C07C253/34 , C07C255/34 , C07C255/59 , C07D307/87 , C12P7/22 , C12P13/001 , C12P13/002 , C12P13/008 , C12P13/02 , C12P41/007
摘要： The present invention relates to a novel method for the preparation of diol intermediates having the formula (II) and/or the opposite enantiomer of an acylated diol having the formula (IV) useful for the preparation of escitalopram involving selective enzymatic acylation or deacylation.
摘要翻译：本发明涉及一种制备具有式（II）的二醇中间体和/或具有式（Ⅳ）的酰化二醇的相反对映异构体的新方法，其可用于制备涉及选择性酶酰化或脱酰基化的依他普仑。

2. 发明申请

US20110065937A1 METHOD FOR THE SEPARATION OF INTERMEDIATES WHICH MAY BE USED FOR THE PREPARATION OF ESCITALOPRAM 失效
标题翻译：用于分离可用于制备ESCITALOPRAM的中间体的方法
公开(公告)号：US20110065937A1
公开(公告)日：2011-03-17
申请号：US12781026
申请日：2010-05-17
申请人： Naoki Taoka , Takahisa Kato , Shogo Yamamoto , Takashi Yoshida , Toshihiro Takeda , Yasuyoshi Ueda , Hans Petersen , Robert Dancer , Haleh Ahmadian , Lars O. Lyngso
发明人： Naoki Taoka , Takahisa Kato , Shogo Yamamoto , Takashi Yoshida , Toshihiro Takeda , Yasuyoshi Ueda , Hans Petersen , Robert Dancer , Haleh Ahmadian , Lars O. Lyngso
IPC分类号： C07D307/87
CPC分类号： C07B57/00 , C07B2200/07 , C07C253/30 , C07C253/34 , C07C255/34 , C07C255/59 , C07D307/87 , C12P7/22 , C12P13/001 , C12P13/002 , C12P13/008 , C12P13/02 , C12P41/007
摘要： The present invention relates to a novel method for the preparation of diol intermediates having the formula (II) and/or the opposite enantiomer of an acylated diol having the formula (IV) useful for the preparation of escitalopram involving selective enzymatic acylation or deacylation.
摘要翻译：本发明涉及一种制备具有式（II）的二醇中间体和/或具有式（Ⅳ）的酰化二醇的相反对映异构体的新方法，其可用于制备涉及选择性酶酰化或脱酰基化的依他普仑。

3. 发明申请

US20070129561A1 Method for the separation of intermediates which may be used for the preparation of escitalopram 审中-公开
标题翻译：用于分离可用于制备依他普仑的中间体的方法
公开(公告)号：US20070129561A1
公开(公告)日：2007-06-07
申请号：US10524937
申请日：2003-08-12
申请人： Naoki Taoka , Takahisa Kato , Shogo Yamamoto , Takashi Yoshida , Toshihiro Takeda , Yasuyoshi Ueda , Hans Petersen , Robert Dancer , Haleh Ahmadian , Lars Lyngso
发明人： Naoki Taoka , Takahisa Kato , Shogo Yamamoto , Takashi Yoshida , Toshihiro Takeda , Yasuyoshi Ueda , Hans Petersen , Robert Dancer , Haleh Ahmadian , Lars Lyngso
IPC分类号： C07C323/20 , C07C271/40 , C12P13/00 , C12P7/22
CPC分类号： C07B57/00 , C07B2200/07 , C07C253/30 , C07C253/34 , C07C255/34 , C07C255/59 , C07D307/87 , C12P7/22 , C12P13/001 , C12P13/002 , C12P13/008 , C12P13/02 , C12P41/007
摘要： The present invention relates to a novel method for the preparation of diol intermediates having the formula (II) and/or the opposite enantiomer of an acylated diol having the formula (IV) useful for the preparation of escitalopram involving selective enzymatic acylation or deacylation.
摘要翻译：本发明涉及一种制备具有式（II）的二醇中间体和/或具有式（Ⅳ）的酰化二醇的相反对映异构体的新方法，其可用于制备涉及选择性酶酰化或脱酰基化的依他普仑。

4. 发明授权

US09315839B2 Processes for producing coenzyme Q10 有权
标题翻译：生产辅酶Q10的方法
公开(公告)号：US09315839B2
公开(公告)日：2016-04-19
申请号：US13020500
申请日：2011-02-03
申请人： Kazuyoshi Yajima , Takahisa Kato , Akihisa Kanda , Shiro Kitamura , Yasuyoshi Ueda
发明人： Kazuyoshi Yajima , Takahisa Kato , Akihisa Kanda , Shiro Kitamura , Yasuyoshi Ueda
IPC分类号： C12P7/66 , C12P7/22
CPC分类号： C12P7/66 , C12P7/22
摘要： The present invention relates to a process for producing reduced coenzyme Q10 which comprises obtaining microbial cells containing reduced coenzyme Q10 at a ratio of not less than 70 mole % among the entire coenzymes Q10, optionally disrupting the cells and recovering thus produced reduced coenzyme Q10. The present invention also relates to a process for producing oxidized coenzyme Q10 which comprises either recovering oxidized coenzyme Q10 after oxidizing the above-mentioned microbial cells or disrupted product thereof, or recovering reduced coenzyme Q10 from the above-mentioned microbial cells or disrupted product thereof to oxidize thus-obtained reduced coenzyme Q10 thereafter. According to the processes of the present invention, reduced coenzyme Q10 and oxidized coenzyme Q10 can be produced simply on the industrial scale.
摘要翻译：本发明涉及一种还原型辅酶Q10的制备方法，其包括在整个辅酶Q10中获得含有还原型辅酶Q10比例不小于70摩尔％的微生物细胞，任选地破坏细胞并回收所生成的还原型辅酶Q10。本发明还涉及氧化型辅酶Q10的制造方法，该方法包括在氧化上述微生物细胞或其破坏的产物后回收氧化型辅酶Q10，或将还原型辅酶Q10从上述微生物细胞或其破坏性产物回收至此后氧化由此得到的还原型辅酶Q10。根据本发明的方法，可以简单地在工业规模上制备还原型辅酶Q10和氧化型辅酶Q10。

5. 发明授权

US07910340B2 Processes for producing coenzyme Q10 有权
标题翻译：生产辅酶Q10的方法
公开(公告)号：US07910340B2
公开(公告)日：2011-03-22
申请号：US11981181
申请日：2007-10-31
申请人： Kazuyoshi Yajima , Takahisa Kato , Akihisa Kanda , Shiro Kitamura , Yasuyoshi Ueda
发明人： Kazuyoshi Yajima , Takahisa Kato , Akihisa Kanda , Shiro Kitamura , Yasuyoshi Ueda
IPC分类号： C12P1/00 , C12P7/66
CPC分类号： C12P7/66 , C12P7/22
摘要： The present invention relates to a process for producing reduced coenzyme Q10 which comprises obtaining microbial cells containing reduced coenzyme Q10 at a ratio of not less than 70 mole % among the entire coenzymes Q10, optionally disrupting the cells and recovering thus-produced reduced coenzyme Q10. The present invention also relates to a process for producing oxidized coenzyme Q10 which comprises either recovering oxidized coenzyme Q10 after oxidizing the above-mentioned microbial cells or disrupted product thereof, or recovering reduced coenzyme Q10 from the above-mentioned microbial cells or disrupted product thereof to oxidize thus-obtained reduced coenzyme Q10 thereafter. According to the processes of the present invention, reduced coenzyme Q10 and oxidized coenzyme Q10 can be produced simply on the industrial scale.
摘要翻译：本发明涉及还原型辅酶Q10的制备方法，其包括在整个辅酶Q10中获得含有不少于70摩尔％的还原型辅酶Q10的微生物细胞，任选地破坏细胞并回收如此生产的还原型辅酶Q10。本发明还涉及氧化型辅酶Q10的制造方法，该方法包括在氧化上述微生物细胞或其破坏的产物后回收氧化型辅酶Q10，或将还原型辅酶Q10从上述微生物细胞或其破坏性产物回收至此后氧化由此得到的还原型辅酶Q10。根据本发明的方法，可以简单地在工业规模上制备还原型辅酶Q10和氧化型辅酶Q10。

6. 发明申请

US20050069996A1 Processes for producing coenzyme q10 审中-公开
标题翻译：生产辅酶q10的方法
公开(公告)号：US20050069996A1
公开(公告)日：2005-03-31
申请号：US10500249
申请日：2002-12-27
申请人： Kazuyoshi Yajima , Takahisa Kato , Akihisa Kanda , Shiro Kitamura , Yasuyoshi Ueda
发明人： Kazuyoshi Yajima , Takahisa Kato , Akihisa Kanda , Shiro Kitamura , Yasuyoshi Ueda
IPC分类号： C12N1/14 , C12N1/20 , C12P7/22 , C12P7/66
CPC分类号： C12P7/66 , C12P7/22
摘要： The present invention relates to a process for producing reduced coenzyme Q10 which comprises obtaining microbial cells containing reduced coenzyme Q10 at a ratio of not less than 70 mole % among the entire coenzymes Q10, optionally disrupting the cells and recovering thus-produced reduced coenzyme Q10. The present invention also relates to a process for producing oxidized coenzyme Q10 which comprises either recovering oxidized coenzyme Q10 after oxidizing the above-mentioned microbial cells or disrupted product thereof, or recovering reduced coenzyme Q10 from the above-mentioned microbial cells or disrupted product thereof to oxidize thus-obtained reduced coenzyme Q10 thereafter. According to the processes of the present invention, reduced coenzyme Q10 and oxidized coenzyme Q10 can be produced simply on the industrial scale.
摘要翻译：本发明涉及还原型辅酶Q10的制备方法，其包括在整个辅酶Q10中获得含有不少于70摩尔％的还原型辅酶Q10的微生物细胞，任选地破坏细胞并回收如此生产的还原型辅酶Q10。本发明还涉及氧化型辅酶Q10的制造方法，该方法包括在氧化上述微生物细胞或其破坏的产物后回收氧化型辅酶Q10，或将还原型辅酶Q10从上述微生物细胞或其破坏性产物回收至此后氧化由此得到的还原型辅酶Q10。根据本发明的方法，可以简单地在工业规模上制备还原型辅酶Q10和氧化型辅酶Q10。

7. 发明申请

US20080171373A1 Processes for producing coenzyme Q10 有权
标题翻译：生产辅酶Q10的方法
公开(公告)号：US20080171373A1
公开(公告)日：2008-07-17
申请号：US11981181
申请日：2007-10-31
申请人： Kazuyoshi Yajima , Takahisa Kato , Akihisa Kanda , Shiro Kitamura , Yasuyoshi Ueda
发明人： Kazuyoshi Yajima , Takahisa Kato , Akihisa Kanda , Shiro Kitamura , Yasuyoshi Ueda
IPC分类号： C12N9/00
CPC分类号： C12P7/66 , C12P7/22
摘要： The present invention relates to a process for producing reduced coenzyme Q10 which comprises obtaining microbial cells containing reduced coenzyme Q10 at a ratio of not less than 70 mole % among the entire coenzymes Q10, optionally disrupting the cells and recovering thus-produced reduced coenzyme Q10. The present invention also relates to a process for producing oxidized coenzyme Q10 which comprises either recovering oxidized coenzyme Q10 after oxidizing the above-mentioned microbial cells or disrupted product thereof, or recovering reduced coenzyme Q10 from the above-mentioned microbial cells or disrupted product thereof to oxidize thus-obtained reduced coenzyme Q10 thereafter. According to the processes of the present invention, reduced coenzyme Q10 and oxidized coenzyme Q10 can be produced simply on the industrial scale.
摘要翻译：本发明涉及一种还原型辅酶Q 10的制备方法，该方法包括：将全部还原型辅酶Q 10的比例不小于70摩尔％的还原型辅酶Q 10 辅酶Q 10，任选地破坏细胞并回收如此生产的还原型辅酶Q 10。本发明还涉及一种生产氧化型辅酶Q 10的方法，其包括在氧化上述微生物细胞或其破坏的产物之后回收氧化型辅酶Q 10，或从上述微生物细胞中回收还原型辅酶Q 10 N或其破坏产物，从而氧化由此得到的还原型辅酶Q 10。根据本发明的方法，可以简单地在工业规模上制备还原型辅酶Q 10和氧化型辅酶Q 10。

8. 发明授权

US08901511B2 Charged particle beam lens and exposure apparatus using the same 有权
公开(公告)号：US08901511B2
公开(公告)日：2014-12-02
申请号：US14004845
申请日：2012-03-14
申请人： Takahisa Kato , Yutaka Setomoto
发明人： Takahisa Kato , Yutaka Setomoto
IPC分类号： H01J37/12 , H01J37/18
摘要： An electrostatic charged particle beam lens includes an electrode including a flat plate having a first surface having a normal line extending in a direction of an optical axis and a second surface opposite to the first surface, the electrode having a through-hole extending from the first surface to the second surface. When an opening cross section is defined as a cross section of the through-hole taken along a plane perpendicular to the normal line and a representative diameter is defined as a diameter of a circle obtained by performing regression analysis of the opening cross section, a representative diameter of the opening cross section in a first region that is on the first surface side and a representative diameter of the opening cross section in a second region that is on the second surface side are smaller than a representative diameter of the opening cross section in a third region that is a region in the electrode disposed between the first surface and the second surface.

9. 发明授权

US08472096B2 Method of manufacturing oscillator device, and optical deflector and optical instrument with oscillator device 有权
标题翻译：制造振荡器装置的方法以及具有振荡器装置的光偏转器和光学仪器
公开(公告)号：US08472096B2
公开(公告)日：2013-06-25
申请号：US12674325
申请日：2008-11-13
申请人： Kazunari Fujii , Takahisa Kato , Yoshio Hotta , Suguru Miyagawa , Takahiro Akiyama
发明人： Kazunari Fujii , Takahisa Kato , Yoshio Hotta , Suguru Miyagawa , Takahiro Akiyama
IPC分类号： G02B26/08
CPC分类号： G02B26/0833 , Y10T29/49826
摘要： A method of manufacturing an oscillator device having first and second oscillators being driven at first and second driving resonance frequencies gf1 and gf2, the method including a first step for processing the two oscillators, wherein, when the two oscillators are going to be processed as oscillators having first and second resonance frequencies different from the two driving resonance frequencies with a certain dispersion range, the two oscillators are so processed that the first and second resonance frequencies different from the two driving resonance frequencies become equal to first and second resonance frequencies f1 and f2, respectively, which are included in adjustable resonance frequency ranges, respectively, and a second step for adjusting the first and second resonance frequencies f1 and f2 so that they become equal to the first and second driving resonance frequencies gf1 and gf2, respectively.
摘要翻译：一种制造具有第一和第二驱动谐振频率gf1和gf2的第一和第二振荡器的振荡器装置的方法，该方法包括用于处理两个振荡器的第一步骤，其中当两个振荡器将被作为振荡器处理时具有与具有一定色散范围的两个驱动谐振频率不同的第一和第二谐振频率，两个振荡器被如此处理，使得与两个驱动谐振频率不同的第一和第二谐振频率变得等于第一和第二谐振频率f1和f2 分别包括在可调节的共振频率范围内，第二步骤用于分别调整第一和第二共振频率f1和f2使得它们分别等于第一和第二驱动谐振频率gf1和gf2。

10. 发明授权

US08191994B2 Liquid ejection head utilizing deflection members 失效
标题翻译：液体喷射头利用偏转构件
公开(公告)号：US08191994B2
公开(公告)日：2012-06-05
申请号：US13079418
申请日：2011-04-04
申请人： Toru Nakakubo , Takahisa Kato , Haruhito Ono , Suguru Miyagawa
发明人： Toru Nakakubo , Takahisa Kato , Haruhito Ono , Suguru Miyagawa
IPC分类号： B41J2/04
CPC分类号： B41J2/175 , B41J2/085 , B41J2/09 , B41J2/18
摘要： Provided is a continuous-type charge deflection liquid ejection head that is suitable for higher-density and multiple nozzles. This liquid ejection head includes: an orifice plate having a plurality of nozzles arranged in a two-dimensional manner; a charging electrode plate having a charging electrode to charge ink droplets from each of the plurality of nozzles; and first and second deflection electrode plates each having a deflection electrode to deflect each of the ink droplets charged by the charging electrode, in which each of the charging member, the first deflection member, and the second deflection member has through-holes that ink droplets pass through, and the charging member, the first deflection member, and the second deflection member are laminated in this order in an ejecting direction of the ink droplets.
摘要翻译：提供适用于更高密度和多个喷嘴的连续型电荷偏转液体喷射头。该液体喷射头包括：具有以二维方式布置的多个喷嘴的孔板; 充电电极板，具有用于对来自所述多个喷嘴中的每一个喷嘴的墨滴充电的充电电极; 以及第一和第二偏转电极板，每个偏转电极板具有偏转电极，以使由充电电极充电的每个墨滴偏转，其中充电部件，第一偏转部件和第二偏转部件中的每一个具有通孔，并且充电构件，第一偏转构件和第二偏转构件按照墨滴的排出方向依次层叠。

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