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1. 发明申请

US20110015099A1 NON BIO-ADHESIVE POLYMER COATING COMPOSITION, ARTICLES AND DEVICES THEREOF 失效
标题翻译：非生物胶粘聚合物涂料组合物，其制品及其装置
公开(公告)号：US20110015099A1
公开(公告)日：2011-01-20
申请号：US12503581
申请日：2009-07-15
申请人： Mingna Xiong , Bing Zhang , Liping Zheng , Hui Lei , Su Lu , Liming Yu , Lin Chen , Wenqing Peng , Yanrong Zhu
发明人： Mingna Xiong , Bing Zhang , Liping Zheng , Hui Lei , Su Lu , Liming Yu , Lin Chen , Wenqing Peng , Yanrong Zhu
IPC分类号： C40B60/00 , C08G77/04 , C09D5/16 , C12M1/00 , B01L3/00 , B32B27/08 , B32B27/06
CPC分类号： G01N33/54393 , B01L3/50 , C08G77/26 , C08G77/28 , C08G77/60 , C08L83/04 , C08L83/08 , C09D5/1675 , Y10T428/31612 , Y10T428/31663
摘要： The invention is a device comprising a substrate and a material provided on at least a portion of the substrate and having an exposed surface. The exposed surface of the material is non bio-adhesive. The invention further includes a non bio-adhesive material composition and a method of making a device having the same non bio-adhesive surface. The invention further provides a device having a coating of a hydrophobic material. In particular, the hydrophobic material coated portion of the device is resistant to bio-adhesion.
摘要翻译：本发明是一种器件，其包括衬底和设置在衬底的至少一部分上并具有暴露表面的材料。材料的暴露表面是非生物粘合剂。本发明还包括非生物粘合剂材料组合物和制造具有相同非生物粘合剂表面的装置的方法。本发明还提供了具有疏水性材料的涂层的装置。特别地，该装置的疏水材料涂覆部分具有抗生物粘附性。

2. 发明授权

US08778278B2 Non bio-adhesive polymer coating composition, articles and devices thereof 失效
标题翻译：非生物粘合剂聚合物涂料组合物，其制品及其装置
公开(公告)号：US08778278B2
公开(公告)日：2014-07-15
申请号：US12503581
申请日：2009-07-15
申请人： Mingna Xiong , Bing Zhang , Liping Zheng , Hui Lei , Su Lu , Liming Yu , Lin Chen , Wenqing Peng , Yanrong Zhu
发明人： Mingna Xiong , Bing Zhang , Liping Zheng , Hui Lei , Su Lu , Liming Yu , Lin Chen , Wenqing Peng , Yanrong Zhu
IPC分类号： B01L3/00
CPC分类号： G01N33/54393 , B01L3/50 , C08G77/26 , C08G77/28 , C08G77/60 , C08L83/04 , C08L83/08 , C09D5/1675 , Y10T428/31612 , Y10T428/31663
摘要： The invention is a device comprising a substrate and a material provided on at least a portion of the substrate and having an exposed surface. The exposed surface of the material is non bio-adhesive. The invention further includes a non bio-adhesive material composition and a method of making a device having the same non bio-adhesive surface. The invention further provides a device having a coating of a hydrophobic material. In particular, the hydrophobic material coated portion of the device is resistant to bio-adhesion.
摘要翻译：本发明是一种器件，其包括衬底和设置在衬底的至少一部分上并具有暴露表面的材料。材料的暴露表面是非生物粘合剂。本发明还包括非生物粘合剂材料组合物和制造具有相同非生物粘合剂表面的装置的方法。本发明还提供了具有疏水性材料的涂层的装置。特别地，该装置的疏水材料涂覆部分具有抗生物粘附性。

3. 发明授权

US09539370B2 Medical device using sulfonated neutralized polymers with reduced adhesion of biological fluids 有权
标题翻译：使用磺化中和聚合物的医疗设备降低生物流体的粘附力
公开(公告)号：US09539370B2
公开(公告)日：2017-01-10
申请号：US12546973
申请日：2009-08-25
申请人： Robert R. Gallucci , Jan Henk Kamps , Jon M. Malinoski , Liming Yu
发明人： Robert R. Gallucci , Jan Henk Kamps , Jon M. Malinoski , Liming Yu
IPC分类号： A61L27/18 , A61L31/06 , A61L29/06
CPC分类号： A61L31/06 , A61L27/18 , A61L29/06 , C08L67/04 , C08L69/00
摘要： A medical article having neutralized sulfonic acid groups on its surface, is disclosed. The article has reduced interaction with biological fluids such as insulin, human growth hormone and human serum albumin.
摘要翻译：公开了一种在其表面上中和磺酸基的医疗制品。该文章减少了与生物流体如胰岛素，人生长激素和人血清白蛋白的相互作用。

4. 发明申请

US20100133181A1 SYSTEMS AND METHODS FOR PROCESSING COMPLEX BIOLOGICAL MATERIALS 有权
标题翻译：用于处理复杂生物材料的系统和方法
公开(公告)号：US20100133181A1
公开(公告)日：2010-06-03
申请号：US12325672
申请日：2008-12-01
申请人： Nichole Lea Wood , Reginald Donovan Smith , Hongyi Zhou , Liming Yu , Brian Polizzotti , Peter Miller
发明人： Nichole Lea Wood , Reginald Donovan Smith , Hongyi Zhou , Liming Yu , Brian Polizzotti , Peter Miller
IPC分类号： B01D61/24 , B01D61/58 , B01D61/30 , B01D65/02 , B01D61/32
CPC分类号： G01N33/491 , A61M1/029 , B01D61/28 , B01D61/30 , B01D63/02 , B01D2313/18 , B01D2313/50 , C12N5/0647 , C12N5/0665 , G01N1/4077 , G01N2001/4083 , G01N2001/4088
摘要： Method and systems, for processing biological material, that contain a biological material in a vessel; add an aggregating agent to the material in the vessel and allow the material to separate into two or more distinct submaterials; extract one or more of the submaterials from the vessel; automatically transport one or more of the submaterials remaining in the vessel to a filtration device; and collect a resulting target retentate into a target retentate receptacle.
摘要翻译：用于处理在容器中含有生物材料的生物材料的方法和系统; 向容器中的材料添加聚集剂，并使材料分离成两个或更多不同的子材料; 从容器中提取一种或多种副材料; 将剩余在容器中的一种或多种副材料自动输送到过滤装置; 并将得到的目标滞留物收集到目标滞留容器中。

5. 发明申请

US20080305504A1 Compositions, methods, and kits for assaying complement activation 失效
标题翻译：用于测定补体激活的组合物，方法和试剂盒
公开(公告)号：US20080305504A1
公开(公告)日：2008-12-11
申请号：US11811425
申请日：2007-06-08
申请人： Liming Yu , Anup Sood , Mark Felipe Baptista
发明人： Liming Yu , Anup Sood , Mark Felipe Baptista
IPC分类号： C12N9/00 , G01N33/53
CPC分类号： C07K14/472 , C12Q1/37 , G01N2333/96441
摘要： The present invention provides a fluorogenic composition for assaying complement activation that comprises a substrate for C3 convertase that is linked to a first fluorophore and a second fluorophore, wherein the fluorescence of the first and second fluorophores are mutually substantially quenched when the two fluorophores are present at a distance less than the characteristic distance for the two fluorophores. In one embodiment, the fluorescence of the first fluorophore is substantially quenched by the second fluorophore, and the second fluorophore emits heat upon quenching. The present invention also provides a method for assaying complement activation, wherein the method includes the steps of incubating a biological sample with a polymer to provide a polymeric biological sample, followed by incubating the polymeric biological sample with the fluorogenic composition, and measuring the fluorescence. The method may optionally include the step of measuring the optical properties of the biological sample prior to the incubation steps. The present invention further provides a kit for assaying complement activation that comprises the fluorogenic composition disclosed herein.
摘要翻译：本发明提供了用于测定补体活化的荧光组合物，其包含与第一荧光团和第二荧光团连接的C3转化酶底物，其中当两个荧光团存在于第一荧光团和第二荧光团时，第一和第二荧光团的荧光相互基本上骤冷距离小于两个荧光团的特征距离。在一个实施方案中，第一荧光团的荧光基本上被第二荧光团猝灭，第二荧光团在淬火时发出热。本发明还提供了用于测定补体活化的方法，其中该方法包括以下步骤：用聚合物孵育生物样品以提供聚合生物样品，随后将聚合物生物样品与荧光组合物一起温育，并测量荧光。该方法可以可选地包括在孵育步骤之前测量生物样品的光学性质的步骤。本发明还提供了用于测定补体活化的试剂盒，其包含本文公开的荧光组合物。

6. 发明授权

US07463035B2 Method and apparatus for the use of multicomponent induction tool for geosteering and formation resistivity data interpretation in horizontal wells 有权
标题翻译：在水平井中使用多组分感应工具进行地质导向和地层电阻率数据解释的方法和装置
公开(公告)号：US07463035B2
公开(公告)日：2008-12-09
申请号：US10373365
申请日：2003-02-24
申请人： Gulamabbas A. Merchant , Otto N. Fanini , Berthold Kriegshauser , Liming Yu
发明人： Gulamabbas A. Merchant , Otto N. Fanini , Berthold Kriegshauser , Liming Yu
IPC分类号： G01V3/10
CPC分类号： E21B47/022 , G01V3/28
摘要： Measurements made with a multicomponent logging instrument when used in a substantially horizontal borehole in earth formations are diagnostic of the direction of beds relative to the position of the borehole. When the logging instrument is conveyed on a drilling assembly, the drilling trajectory may be maintained to follow a predetermined trajectory or to maintain a desired distance from a boundary such as an oil-water contact.
摘要翻译：使用多组分测井仪器在地层中基本上水平的井眼中进行的测量是相对于钻孔位置的床的方向的诊断。当测井仪器在钻井组件上传送时，钻井轨迹可以被维持以遵循预定轨迹或者保持与诸如油 - 水接触的边界的期望距离。

7. 发明申请

US20070208546A1 Real time data quality control and determination of formation angles from multicomponent induction measurements using neural networks 有权
标题翻译：使用神经网络的多组分感应测量的实时数据质量控制和形成角度的确定
公开(公告)号：US20070208546A1
公开(公告)日：2007-09-06
申请号：US11368906
申请日：2006-03-06
申请人： Sheng Fang , Leonty Tabarovsky , Michael Rabinovich , Liming Yu
发明人： Sheng Fang , Leonty Tabarovsky , Michael Rabinovich , Liming Yu
IPC分类号： G06F19/00
CPC分类号： G01V3/28
摘要： Neural networks may be used to determine and predict formation dip angles and perform quality assurance assessments from data collected with a multi-component induction tool used for well logging. The neural networks make use of corrected, rotated and normalized data to provide the predictions and assessments. Synthetic data using various models is used to train the neural networks. The teachings herein provide for real-time determinations with a substantial degree of accuracy in the results.
摘要翻译：可以使用神经网络来确定和预测地层倾角，并通过用于测井的多组分感应工具收集的数据进行质量保证评估。神经网络使用校正，旋转和归一化的数据来提供预测和评估。使用各种模型的合成数据用于训练神经网络。本文的教导提供了在结果中具有相当程度的准确性的实时确定。

8. 发明授权

US07719282B2 Method and apparatus for mulit-component induction instrument measuring system for geosteering and formation resistivity data interpretation in horizontal, vertical and deviated wells 有权
标题翻译：用于水平，垂直和偏斜井的地质导向和地层电阻率数据解释的多分量感应仪测量系统的方法和装置
公开(公告)号：US07719282B2
公开(公告)日：2010-05-18
申请号：US11780364
申请日：2007-07-19
申请人： Otto N. Fanini , Stanislav W. Forgang , Berthold Kriegshauser , Liming Yu
发明人： Otto N. Fanini , Stanislav W. Forgang , Berthold Kriegshauser , Liming Yu
IPC分类号： G01V3/08 , G01V3/10
CPC分类号： G01V3/28
摘要： An improved induction tool for evaluating formation resistivity. The tool provides electromagnetic transmitters and sensors suitable for transmitting and receiving magnetic fields in radial directions that are orthogonal to the tool's longitudinal axis with minimal susceptibility to errors associated with parasitic eddy currents induced in the metal components surrounding the transmitter and receiver coils. A magnetic lens is provided to select sensitivity to a desired reservoir formation property.
摘要翻译：一种用于评估地层电阻率的改进的感应工具。该工具提供电磁发射器和传感器，适用于在与工具的纵向轴线正交的径向方向上发射和接收磁场，对与发射器和接收器线圈周围的金属部件中感应的寄生涡流有关的误差的影响最小。提供磁性透镜以选择对期望的储层形成性质的灵敏度。

9. 发明申请

US20090269790A1 Method and Apparatus for Determining Hemocompatibility 有权
标题翻译：测定血液相容性的方法和装置
公开(公告)号：US20090269790A1
公开(公告)日：2009-10-29
申请号：US12110104
申请日：2008-04-25
申请人： Liming Yu , Aaron Dulgar Tulloch
发明人： Liming Yu , Aaron Dulgar Tulloch
IPC分类号： G01N33/53 , G01N33/00 , G01N33/566
CPC分类号： G01N33/86
摘要： Provided herein are techniques for screening materials for hemocompatibility. Hemocompatible materials may be advantageous when incorporated into devices that may come into direct contact with blood or other bodily fluids. Such techniques take advantage of conformational changes in fibrinogen when adsorbed onto certain materials. As a result of conformational changes, the fibrinogen has altered responsiveness to cleavage by thrombin. Accordingly, the products of thrombin cleavage of fibrinogen may be assessed to determine the hemocompatibility of a material.
摘要翻译：本文提供了用于筛选血液相容性的材料的技术。当结合到可能与血液或其他体液直接接触的装置中时，血液相容性材料可能是有利的。当吸附到某些材料上时，这种技术利用纤维蛋白原的构象变化。作为构象变化的结果，纤维蛋白原已经改变了对凝血酶切割的反应性。因此，可以评估纤维蛋白原凝血酶切割的产物以确定材料的血液相容性。

10. 发明授权

US07471088B2 Elimination of the anisotropy effect in LWD azimuthal resistivity tool data 有权
标题翻译：消除LWD方位电阻率工具数据中的各向异性效应
公开(公告)号：US07471088B2
公开(公告)日：2008-12-30
申请号：US11298255
申请日：2005-12-09
申请人： Liming Yu , Tsili Wang , Jack Signorelli
发明人： Liming Yu , Tsili Wang , Jack Signorelli
IPC分类号： G01V3/18
CPC分类号： E21B47/024 , G01V3/28
摘要： Cross-component measurements made with a dual-transmitter configuration are processed to estimate a distance to an interface in an anisotropic earth formation. Optionally, measurements may be made with two receivers, also in the dual transmitter configuration.
摘要翻译：处理使用双发射器配置进行的跨分量测量，以估计到各向异性地层中的界面的距离。可选地，也可以在两个发射机配置中使用两个接收机进行测量。

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