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1. 发明授权

US5916213A Systems and methods for tissue mapping and ablation 失效
标题翻译：用于组织测绘和消融的系统和方法
公开(公告)号：US5916213A
公开(公告)日：1999-06-29
申请号：US794804
申请日：1997-02-04
申请人： Michel Haissaguerre , Walter Bruszewski , Le Le , Mark Maguire , John Gaiser , Huu Nguyen
发明人： Michel Haissaguerre , Walter Bruszewski , Le Le , Mark Maguire , John Gaiser , Huu Nguyen
IPC分类号： A61B5/0402 , A61B18/08 , A61B18/12 , A61B18/14 , A61M25/00 , A61B17/39
CPC分类号： A61B18/08 , A61B18/1492 , A61B2017/003 , A61B2017/2945 , A61B2018/00011 , A61B2018/00029 , A61B2018/0016 , A61B2018/00214 , A61B2018/00351 , A61B2018/00577 , A61B2018/00839 , A61B2018/00898 , A61B2018/0091 , A61B2018/1432 , A61B2018/1467 , A61B2018/1472 , A61B2218/002
摘要： A steerable electrophysiology catheter includes a shaft having a distal ablation segment with one or more electrodes coupled to a source of electrical energy by a connector extending through the shaft. The distal ablation segment of the shaft is movable between a collapsed configuration sized for percutaneous introduction into the patient and/or endoluminal delivery to the target site and an expanded configuration, in which the distal ablation segment forms a substantially continuous surface transverse to the shaft axis for engaging the heart tissue and creating a linear lesion thereon. The catheter includes one or more force element(s) positioned to apply an axial force between the distal and proximal ends of the ablation segment. The force element(s) provide a sufficiently uniform force against the distal ablation segment to establish continuous contact pressure between the electrodes and the patient's heart tissue. This contact pressure allows the surgeon to engage the entire length of the distal ablation segment against the heart tissue to provide a relatively long linear lesion on this tissue.
摘要翻译：可引导的电生理导管包括具有远端消融段的轴，其具有通过延伸穿过轴的连接器而与电源耦合的一个或多个电极。轴的远端消融段可在被定形成经皮引入患者体内和/或腔内递送到目标部位的膨胀构型和扩张构型之间移动，其中远侧消融段形成横向于轴线的基本上连续的表面用于接合心脏组织并在其上产生线性损伤。导管包括定位成在消融段的远端和近端之间施加轴向力的一个或多个力元件。力元件提供足够均匀的力抵抗远端消融段，以在电极和患者的心脏组织之间建立连续的接触压力。该接触压力允许外科医生将远端消融段的整个长度接合心脏组织以在该组织上提供相对较长的线性损伤。

2. 发明授权

US6068629A System and methods for tissue mapping and ablation 有权
标题翻译：用于组织测绘和消融的系统和方法
公开(公告)号：US6068629A
公开(公告)日：2000-05-30
申请号：US213332
申请日：1998-12-15
申请人： Michel Haissaguerre , Walter Bruszewski , Le Le , Mark Maguire , John Gaiser , Huu Nguyen
发明人： Michel Haissaguerre , Walter Bruszewski , Le Le , Mark Maguire , John Gaiser , Huu Nguyen
IPC分类号： A61B5/0402 , A61B18/08 , A61B18/12 , A61B18/14 , A61M25/00 , A61B17/39
CPC分类号： A61B18/08 , A61B18/1492 , A61B2017/003 , A61B2017/2945 , A61B2018/00011 , A61B2018/00029 , A61B2018/0016 , A61B2018/00214 , A61B2018/00351 , A61B2018/00577 , A61B2018/00839 , A61B2018/00898 , A61B2018/0091 , A61B2018/1432 , A61B2018/1467 , A61B2018/1472 , A61B2218/002
摘要： A steerable electrophysiology catheter includes a shaft having a distal ablation segment with one or more electrodes coupled to a source of electrical energy by a connector extending through the shaft. The distal ablation segment of the shaft is movable between a collapsed configuration sized for percutaneous introduction into the patient and/or endoluminal delivery to the target site and an expanded configuration, in which the distal ablation segment forms a substantially continuous surface transverse to the shaft axis for engaging the heart tissue and creating a linear lesion thereon. The catheter includes one or more force element(s) positioned to apply an axial force between the distal and proximal ends of the ablation segment. The force element(s) provide a sufficiently uniform force against the distal ablation segment to establish continuous contact pressure between the electrodes and the patient's heart tissue. This contact pressure allows the surgeon to engage the entire length of the distal ablation segment against the heart tissue to provide a relatively long linear lesion on this tissue.
摘要翻译：可引导的电生理导管包括具有远端消融段的轴，其具有通过延伸穿过轴的连接器而与电源耦合的一个或多个电极。轴的远端消融段可在被定形成经皮引入患者体内和/或腔内递送到目标部位的膨胀构型和扩张构型之间移动，其中远侧消融段形成横向于轴线的基本上连续的表面用于接合心脏组织并在其上产生线性损伤。导管包括定位成在消融段的远端和近端之间施加轴向力的一个或多个力元件。力元件提供足够均匀的力抵抗远端消融段，以在电极和患者的心脏组织之间建立连续的接触压力。该接触压力允许外科医生将远端消融段的整个长度接合心脏组织以在该组织上提供相对较长的线性损伤。

3. 发明授权

US08142493B2 Method of heart valve repair 有权
标题翻译：心脏瓣膜修复方法
公开(公告)号：US08142493B2
公开(公告)日：2012-03-27
申请号：US12177554
申请日：2008-07-22
申请人： Paul A. Spence , Walter Bruszewski , Ed McNamara , Mark Maguire
发明人： Paul A. Spence , Walter Bruszewski , Ed McNamara , Mark Maguire
IPC分类号： A61F2/24
CPC分类号： A61F2/2466 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/064 , A61B2017/00398 , A61B2017/00862 , A61B2017/00867 , A61B2017/00876 , A61B2017/0406 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0454 , A61B2017/0458 , A61B2017/0464 , A61B2017/0496 , A61B2017/0641 , A61B2017/0647 , A61F2/2445 , A61F2/2451 , Y10S623/904
摘要： Catheter based systems and methods for securing tissue including the annulus of a mitral valve. The systems and methods employ catheter based techniques and devices to plicate tissue and perform an annuloplasty.
摘要翻译：基于导管的系统和用于固定包括二尖瓣环的组织的方法。该系统和方法采用基于导管的技术和装置来剔除组织并执行瓣环成形术。

4. 发明授权

US07431726B2 Tissue fastening systems and methods utilizing magnetic guidance 有权
标题翻译：使用磁引导的组织紧固系统和方法
公开(公告)号：US07431726B2
公开(公告)日：2008-10-07
申请号：US10948922
申请日：2004-09-24
申请人： Paul A. Spence , Walter Bruszewski , Ed McNamara , Mark Maguire
发明人： Paul A. Spence , Walter Bruszewski , Ed McNamara , Mark Maguire
IPC分类号： A61B17/064 , A61F2/24
CPC分类号： A61F2/2466 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/064 , A61B2017/00398 , A61B2017/00862 , A61B2017/00867 , A61B2017/00876 , A61B2017/0406 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0454 , A61B2017/0458 , A61B2017/0464 , A61B2017/0496 , A61B2017/0641 , A61B2017/0647 , A61F2/2445 , A61F2/2451 , Y10S623/904
摘要： Catheter based systems and methods for securing tissue including the annulus of a mitral valve. The systems and methods employ catheter based techniques and devices to plicate tissue and perform an annuloplasty.
摘要翻译：基于导管的系统和用于固定包括二尖瓣环的组织的方法。该系统和方法采用基于导管的技术和装置来剔除组织并执行瓣环成形术。

5. 发明申请

US20050137700A1 Tissue fastening systems and methods utilizing magnetic guidance 有权
标题翻译：使用磁引导的组织紧固系统和方法
公开(公告)号：US20050137700A1
公开(公告)日：2005-06-23
申请号：US10949134
申请日：2004-09-24
申请人： Paul Spence , Mark Maguire , Michael Sansoucy , Walter Bruszewski
发明人： Paul Spence , Mark Maguire , Michael Sansoucy , Walter Bruszewski
IPC分类号： A61B17/00 , A61B17/04 , A61B17/064 , A61F2/24
CPC分类号： A61F2/2466 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/064 , A61B2017/00398 , A61B2017/00862 , A61B2017/00867 , A61B2017/00876 , A61B2017/0406 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0454 , A61B2017/0458 , A61B2017/0464 , A61B2017/0496 , A61B2017/0641 , A61B2017/0647 , A61F2/2445 , A61F2/2451 , Y10S623/904
摘要： Catheter based systems and methods for securing tissue including the annulus of a mitral valve. The systems and methods employ catheter based techniques and devices to plicate tissue and perform an annuloplasty.
摘要翻译：基于导管的系统和用于固定包括二尖瓣环的组织的方法。该系统和方法采用基于导管的技术和装置来剔除组织并执行瓣环成形术。

6. 发明申请

US20080275503A1 METHOD OF HEART VALVE REPAIR 有权
标题翻译：心瓣膜修复方法
公开(公告)号：US20080275503A1
公开(公告)日：2008-11-06
申请号：US12177554
申请日：2008-07-22
申请人： Paul A. Spence , Walter Bruszewski , Ed McNamara , Mark Maguire
发明人： Paul A. Spence , Walter Bruszewski , Ed McNamara , Mark Maguire
IPC分类号： A61B17/04 , A61B19/00
CPC分类号： A61F2/2466 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/064 , A61B2017/00398 , A61B2017/00862 , A61B2017/00867 , A61B2017/00876 , A61B2017/0406 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0454 , A61B2017/0458 , A61B2017/0464 , A61B2017/0496 , A61B2017/0641 , A61B2017/0647 , A61F2/2445 , A61F2/2451 , Y10S623/904
摘要： Catheter based systems and methods for securing tissue including the annulus of a mitral valve. The systems and methods employ catheter based techniques and devices to plicate tissue and perform an annuloplasty.
摘要翻译：基于导管的系统和用于固定包括二尖瓣环的组织的方法。该系统和方法采用基于导管的技术和装置来剔除组织并执行瓣环成形术。

7. 发明申请

US20050267571A1 Tissue fastening systems and methods utilizing magnetic guidance 有权
公开(公告)号：US20050267571A1
公开(公告)日：2005-12-01
申请号：US10948922
申请日：2004-09-24
申请人： Paul Spence , Walter Bruszewski , Ed McNamara , Mark Maguire
发明人： Paul Spence , Walter Bruszewski , Ed McNamara , Mark Maguire
IPC分类号： A61B17/00 , A61B17/04 , A61B17/064 , A61F2/24
CPC分类号： A61F2/2466 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/064 , A61B2017/00398 , A61B2017/00862 , A61B2017/00867 , A61B2017/00876 , A61B2017/0406 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0454 , A61B2017/0458 , A61B2017/0464 , A61B2017/0496 , A61B2017/0641 , A61B2017/0647 , A61F2/2445 , A61F2/2451 , Y10S623/904
摘要： Catheter based systems and methods for securing tissue including the annulus of a mitral valve. The systems and methods employ catheter based techniques and devices to plicate tissue and perform an annuloplasty.

8. 发明授权

US07166127B2 Tissue fastening systems and methods utilizing magnetic guidance 有权
标题翻译：使用磁引导的组织紧固系统和方法
公开(公告)号：US07166127B2
公开(公告)日：2007-01-23
申请号：US10949134
申请日：2004-09-24
申请人： Paul A. Spence , Mark Maguire , Michael R. Sansoucy , Walter Bruszewski
发明人： Paul A. Spence , Mark Maguire , Michael R. Sansoucy , Walter Bruszewski
IPC分类号： A61F2/24
CPC分类号： A61F2/2466 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/064 , A61B2017/00398 , A61B2017/00862 , A61B2017/00867 , A61B2017/00876 , A61B2017/0406 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0454 , A61B2017/0458 , A61B2017/0464 , A61B2017/0496 , A61B2017/0641 , A61B2017/0647 , A61F2/2445 , A61F2/2451 , Y10S623/904
摘要： Catheter based systems and methods for securing tissue including the annulus of a mitral valve. The systems and methods employ catheter based techniques and devices to plicate tissue and perform an annuloplasty.
摘要翻译：基于导管的系统和用于固定包括二尖瓣环的组织的方法。该系统和方法采用基于导管的技术和装置来剔除组织并执行瓣环成形术。

9. 发明申请

US20050125011A1 Tissue fastening systems and methods utilizing magnetic guidance 审中-公开
公开(公告)号：US20050125011A1
公开(公告)日：2005-06-09
申请号：US10949133
申请日：2005-01-31
申请人： Paul Spence , Mark Maguire , Walter Bruszewski , Michael Sansoucy , Ed McNamara
发明人： Paul Spence , Mark Maguire , Walter Bruszewski , Michael Sansoucy , Ed McNamara
IPC分类号： A61F2/24 , A61B19/00
CPC分类号： A61F2/2451 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/064 , A61B2017/00398 , A61B2017/00862 , A61B2017/00867 , A61B2017/00876 , A61B2017/0406 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0454 , A61B2017/0464 , A61B2017/0496 , A61B2017/0641 , A61B2017/0647 , A61F2/2445 , A61F2/2466 , A61F2002/30079 , A61F2210/009
摘要： Catheter based systems and methods for securing tissue including the annulus of a mitral valve. The systems and methods employ catheter based techniques and devices to plicate tissue and perform an annuloplasty.

10. 发明授权

US09005270B2 High metal to vessel ratio stent and method 有权
标题翻译：高金属与血管比支架和方法
公开(公告)号：US09005270B2
公开(公告)日：2015-04-14
申请号：US13430942
申请日：2012-03-27
申请人： Keith Perkins , Samuel Robaina , Jeffery Argentine , Walter Bruszewski , Andrew Kiehl
发明人： Keith Perkins , Samuel Robaina , Jeffery Argentine , Walter Bruszewski , Andrew Kiehl
IPC分类号： A61F2/82 , A61F2/915
CPC分类号： A61F2/915 , A61F2002/91525
摘要： A method includes covering ostai of branch vessels emanating from a main vessel and an aneurysm with a high metal to vessel ratio stent. A metal to vessel ratio of the high metal to vessel ratio stent is sufficiently high to encourage tissue ingrowth around the high metal to vessel ratio stent yet is sufficiently low to ensure perfusion of the branch vessels through the high metal to vessel ratio stent. The ingrowth of tissue provides secure fixation and sealing of the high metal to vessel ratio stent to the main vessel and remodels and essentially eliminates the aneurysm. Further, as the entire high metal to vessel ratio stent is permeably, the high metal to vessel ratio stent is deployed without having to rotationally position the high metal to vessel ratio stent.
摘要翻译：一种方法包括覆盖从主血管发出的分支血管和具有高金属与血管比例支架的动脉瘤。高金属与血管比支架的金属与血管比例足够高以促使组织向内生长高金属与血管比例支架，但足够低以确保分支血管通过高金属与血管比例的支架灌注。组织的向内生长提供了高金属与血管比例支架到主血管的牢固固定和密封，并且改造并且基本上消除了动脉瘤。此外，随着整个高金属与血管比例的支架是可渗透的，高金属与血管比例的支架被展开，而不必旋转地定位高金属与血管比例的支架。

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