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1. 发明授权

US08182747B2 Test device for analyzing a biological sample liquid 失效
标题翻译：用于分析生物样品液体的测试装置
公开(公告)号：US08182747B2
公开(公告)日：2012-05-22
申请号：US10628042
申请日：2003-07-25
申请人： Michael Marquant , Volker Unkrig , Fritz Hindelang
发明人： Michael Marquant , Volker Unkrig , Fritz Hindelang
IPC分类号： G01N27/26
CPC分类号： B01L3/502707 , B01L3/502715 , B01L2300/0645 , B01L2300/0654 , B01L2300/0825 , B01L2300/0874 , B01L2300/0887 , B01L2400/0406 , G01N21/11 , G01N21/253 , G01N21/78 , G01N21/8483 , G01N33/49
摘要： The invention concerns a test device for analyzing especially a biological sample liquid comprising a composite body consisting of a plurality of layers of flat materials and a sample channel located in the composite body for transporting the sample liquid from an application site to a measuring site. According to the invention it is proposed that the composite body has a plurality of transport layers arranged in a stack-like manner between support layers for holding in each case sample channel.
摘要翻译：本发明涉及一种用于特别分析生物样品液体的测试装置，其包括由多层扁平材料组成的复合体和位于复合体中的样品通道，用于将样品液体从施用部位输送到测量部位。根据本发明，提出了复合体具有以堆叠方式布置在支撑层之间的多个输送层，用于在每种情况下保持样品通道。

2. 发明申请

US20090020439A1 ELECTROCHEMICAL BIOSENSOR ANALYSIS SYSTEM 有权
标题翻译：电化学生物传感器分析系统
公开(公告)号：US20090020439A1
公开(公告)日：2009-01-22
申请号：US12177566
申请日：2008-07-22
申请人： Michael Marquant , Udo Zapf , Gregor Bainczyk , Volker Unkrig , Mihail-Onoriu Lungu , Holger Kotzan
发明人： Michael Marquant , Udo Zapf , Gregor Bainczyk , Volker Unkrig , Mihail-Onoriu Lungu , Holger Kotzan
IPC分类号： G01N27/26 , G01N27/327
CPC分类号： C12Q1/001 , G01N27/3273 , G01N27/3274
摘要： An electrochemical biosensor analysis system is provided for analyzing a sample liquid, comprising a biosensor having an electrode structure made of at least two electrodes, a test field, covering the electrode structure and capable of absorbing the sample liquid, and a defined sample application surface on the top side of the test field. The system also includes an analysis instrument comprising an evaluation unit for determining the desired analysis data. The analysis instrument comprises an AC resistance measuring device for measuring an AC resistance value between two electrodes of the electrode structure by means of an area compensation measurement. The measured AC resistance value is used, in the determination of the analysis data, as a measure of the partial area of the effective electrode structure area wetted by the sample liquid.
摘要翻译：提供一种用于分析样品液体的电化学生物传感器分析系统，其包括具有由至少两个电极制成的电极结构的生物传感器，覆盖电极结构并能够吸收样品液体的测试场，以及定义的样品施加表面测试领域的顶端。该系统还包括分析仪器，其包括用于确定所需分析数据的评估单元。分析仪器包括用于通过面积补偿测量来测量电极结构的两个电极之间的交流电阻值的交流电阻测量装置。在测定分析数据时，使用测量的AC电阻值作为由样品液体润湿的有效电极结构区域的部分面积的量度。

3. 发明授权

US08137980B2 On-board control for analytical elements 有权
标题翻译：分析元件的车载控制
公开(公告)号：US08137980B2
公开(公告)日：2012-03-20
申请号：US13032443
申请日：2011-02-22
申请人： Volker Unkrig , Christine Nortmeyer , Carina Horn , Michael Marquant , Mihail Onoriu Lungu , Joachim Hoenes , Holger Kotzan , Joerg Dreibholz
发明人： Volker Unkrig , Christine Nortmeyer , Carina Horn , Michael Marquant , Mihail Onoriu Lungu , Joachim Hoenes , Holger Kotzan , Joerg Dreibholz
IPC分类号： G01N21/00 , G01N27/28
CPC分类号： G01N33/54386 , G01N31/22 , G01N33/52 , G01N33/86 , Y10T436/104998 , Y10T436/144444 , Y10T436/17 , Y10T436/170769 , Y10T436/179228
摘要： The invention concerns a reagent system for the so-called on-board control of analytical elements, in particular test strips, containing an organic N-oxide or a nitroso compound. The invention also concerns analytical elements containing a reagent system for a detection reaction and a reagent system for an on-board control. Furthermore, the invention concerns a method for checking analytical elements in which a reagent system for an on-board control is examined optically or electrochemically with the aid of a measuring instrument for changes which could indicate a stress of the analytical element.
摘要翻译：本发明涉及用于所谓的对含有有机N-氧化物或亚硝基化合物的分析元素，特别是试纸的板载控制的试剂系统。本发明还涉及包含用于检测反应的试剂系统和用于车载控制的试剂系统的分析元件。此外，本发明涉及一种用于检查分析元件的方法，其中用于车载控制的试剂系统借助于可以指示分析元件的应力的测量仪器被光学或电化学地检查。

4. 发明授权

US08357274B2 Electrochemical biosensor analysis system 有权
标题翻译：电化学生物传感器分析系统
公开(公告)号：US08357274B2
公开(公告)日：2013-01-22
申请号：US12177566
申请日：2008-07-22
申请人： Michael Marquant , Udo Zapf , Gregor Bainczyk , Volker Unkrig , Mihail-Onoriu Lungu , Holger Kotzan
发明人： Michael Marquant , Udo Zapf , Gregor Bainczyk , Volker Unkrig , Mihail-Onoriu Lungu , Holger Kotzan
IPC分类号： G01N27/327
CPC分类号： C12Q1/001 , G01N27/3273 , G01N27/3274
摘要： An electrochemical biosensor analysis system is provided for analyzing a sample liquid, comprising a biosensor having an electrode structure made of at least two electrodes, a test field, covering the electrode structure and capable of absorbing the sample liquid, and a defined sample application surface on the top side of the test field. The system also includes an analysis instrument comprising an evaluation unit for determining the desired analysis data. The analysis instrument comprises an AC resistance measuring device for measuring an AC resistance value between two electrodes of the electrode structure by means of an area compensation measurement. The measured AC resistance value is used, in the determination of the analysis data, as a measure of the partial area of the effective electrode structure area wetted by the sample liquid.
摘要翻译：提供一种用于分析样品液体的电化学生物传感器分析系统，其包括具有由至少两个电极制成的电极结构的生物传感器，覆盖电极结构并能够吸收样品液体的测试场，以及定义的样品施加表面测试领域的顶端。该系统还包括分析仪器，其包括用于确定所需分析数据的评估单元。分析仪器包括用于通过面积补偿测量来测量电极结构的两个电极之间的交流电阻值的交流电阻测量装置。在测定分析数据时，使用测量的AC电阻值作为由样品液体润湿的有效电极结构区域的部分面积的量度。

5. 发明申请

US20110177605A1 On-Board Control for Analytical Elements 有权
标题翻译：分析元件的车载控制
公开(公告)号：US20110177605A1
公开(公告)日：2011-07-21
申请号：US13032443
申请日：2011-02-22
申请人： Volker Unkrig , Christine Nortmeyer , Carina Horn , Michael Marquant , Mihail-Onoriu Lungu , Joachim Hoenes , Holger Kotzan , Joerg Dreibholz
发明人： Volker Unkrig , Christine Nortmeyer , Carina Horn , Michael Marquant , Mihail-Onoriu Lungu , Joachim Hoenes , Holger Kotzan , Joerg Dreibholz
IPC分类号： G01N21/00 , G01N27/28
CPC分类号： G01N33/54386 , G01N31/22 , G01N33/52 , G01N33/86 , Y10T436/104998 , Y10T436/144444 , Y10T436/17 , Y10T436/170769 , Y10T436/179228
摘要： The invention concerns a reagent system for the so-called on-board control of analytical elements, in particular test strips, containing an organic N-oxide or a nitroso compound. The invention also concerns analytical elements containing a reagent system for a detection reaction and a reagent system for an on-board control. Furthermore, the invention concerns a method for checking analytical elements in which a reagent system for an on-board control is examined optically or electrochemically with the aid of a measuring instrument for changes which could indicate a stress of the analytical element.
摘要翻译：本发明涉及用于所谓的对含有有机N-氧化物或亚硝基化合物的分析元素，特别是试纸的板载控制的试剂系统。本发明还涉及包含用于检测反应的试剂系统和用于车载控制的试剂系统的分析元件。此外，本发明涉及一种用于检查分析元件的方法，其中用于车载控制的试剂系统借助于可以指示分析元件的应力的测量仪器被光学或电化学地检查。

6. 发明授权

US07914752B2 On-board control for analytical elements 有权
标题翻译：分析元件的车载控制
公开(公告)号：US07914752B2
公开(公告)日：2011-03-29
申请号：US10962796
申请日：2004-10-12
申请人： Volker Unkrig , Christine Nortmeyer , Carina Horn , Michael Marquant , Mihail-Onoriu Lungu , Joachim Hoenes , Holger Kotzan , Joerg Dreibholz
发明人： Volker Unkrig , Christine Nortmeyer , Carina Horn , Michael Marquant , Mihail-Onoriu Lungu , Joachim Hoenes , Holger Kotzan , Joerg Dreibholz
IPC分类号： G01N31/22
CPC分类号： G01N33/54386 , G01N31/22 , G01N33/52 , G01N33/86 , Y10T436/104998 , Y10T436/144444 , Y10T436/17 , Y10T436/170769 , Y10T436/179228
摘要： The invention concerns a reagent system for the so-called on-board control of analytical elements, in particular test strips, containing an organic N-oxide or a nitroso compound. The invention also concerns analytical elements containing a reagent system for a detection reaction and a reagent system for an on-board control. Furthermore, the invention concerns a method for checking analytical elements in which a reagent system for an on-board control is examined optically or electrochemically with the aid of a measuring instrument for changes which could indicate a stress of the analytical element.
摘要翻译：本发明涉及用于所谓的对含有有机N-氧化物或亚硝基化合物的分析元素，特别是试纸的板载控制的试剂系统。本发明还涉及包含用于检测反应的试剂系统和用于车载控制的试剂系统的分析元件。此外，本发明涉及一种用于检查分析元件的方法，其中用于车载控制的试剂系统借助于可以指示分析元件的应力的测量仪器被光学或电化学地检查。

7. 发明申请

US20050123441A1 On-board control for analytical elements 有权
标题翻译：分析元件的车载控制
公开(公告)号：US20050123441A1
公开(公告)日：2005-06-09
申请号：US10962796
申请日：2004-10-12
申请人： Volker Unkrig , Christine Nortmeyer , Carina Horn , Michael Marquant , Mihail-Onoriu Lungu , Joachim Hoenes , Holger Kotzan , Joerg Dreibholz
发明人： Volker Unkrig , Christine Nortmeyer , Carina Horn , Michael Marquant , Mihail-Onoriu Lungu , Joachim Hoenes , Holger Kotzan , Joerg Dreibholz
IPC分类号： G01N33/96 , B65D79/02 , C12Q1/00 , G01N21/17 , G01N21/77 , G01N21/78 , G01N27/26 , G01N27/327 , G01N27/416 , G01N31/00 , G01N31/22 , G01N33/487 , G01N33/49 , G01N33/52 , G01N33/53 , G01N33/543 , G01N33/58 , G01N33/86 , G01N37/00
CPC分类号： G01N33/54386 , G01N31/22 , G01N33/52 , G01N33/86 , Y10T436/104998 , Y10T436/144444 , Y10T436/17 , Y10T436/170769 , Y10T436/179228
摘要： The invention concerns a reagent system for the so-called on-board control of analytical elements, in particular test strips, containing an organic N-oxide or a nitroso compound. The invention also concerns analytical elements containing a reagent system for a detection reaction and a reagent system for an on-board control. Furthermore, the invention concerns a method for checking analytical elements in which a reagent system for an on-board control is examined optically or electrochemically with the aid of a measuring instrument for changes which could indicate a stress of the analytical element.
摘要翻译：本发明涉及用于所谓的对含有有机N-氧化物或亚硝基化合物的分析元素，特别是试纸的板载控制的试剂系统。本发明还涉及包含用于检测反应的试剂系统和用于车载控制的试剂系统的分析元件。此外，本发明涉及一种用于检查分析元件的方法，其中用于车载控制的试剂系统借助于可以指示分析元件的应力的测量仪器被光学或电化学地检查。

8. 发明授权

US08828200B2 Electrochemical sensor for the determination of an analyte concentration 有权
标题翻译：用于测定分析物浓度的电化学传感器
公开(公告)号：US08828200B2
公开(公告)日：2014-09-09
申请号：US12367725
申请日：2009-02-09
申请人： Michael Marquant , Gregor Bainczyk
发明人： Michael Marquant , Gregor Bainczyk
IPC分类号： G01N27/327 , A61B5/1486 , A61B5/145
CPC分类号： G01N27/4166 , A61B5/14532 , A61B5/14865 , C25D5/48 , G01N27/301 , G01N27/327 , G01N27/3272 , G01N33/4833 , H01R43/16 , Y10T29/49204
摘要： The invention relates to an electrochemical sensor for the determination of a concentration of at least one analyte in a medium, in particular a body tissue and/or a body fluid, to an apparatus that includes the electrochemical sensor, and to a use of the electrochemical sensor, and finally to a method for producing it. The electrochemical sensor has an isolation element and at least two electrodes. The at least two electrodes comprise at least one working electrode and at least one further electrode, in particular at least one counter electrode and/or at least one reference electrode. The at least two electrodes run parallel to one another and form an electrochemical measuring cell of the electrochemical sensor.
摘要翻译：本发明涉及一种电化学传感器，用于确定介质中的至少一种分析物，特别是身体组织和/或体液的浓度，包括电化学传感器的装置，以及使用电化学传感器，最后是一种生产它的方法。电化学传感器具有隔离元件和至少两个电极。至少两个电极包括至少一个工作电极和至少一个另外的电极，特别是至少一个对电极和/或至少一个参考电极。至少两个电极彼此平行地延伸并形成电化学传感器的电化学测量单元。

9. 发明授权

US08721544B2 System for in-vivo measurement of an analyte concentration 有权
标题翻译：用于体内测量分析物浓度的系统
公开(公告)号：US08721544B2
公开(公告)日：2014-05-13
申请号：US12052382
申请日：2008-03-20
申请人： Bernd Roesicke , Karin Obermaier , Stefan Lindegger , Andreas Menke , Joerg Scherer , Karin Schwind , Otto Gaa , Gregor Bainczyk , Michael Marquant , Sandro Niederhäuser , Michael Schoemaker , Martin Mueri
发明人： Bernd Roesicke , Karin Obermaier , Stefan Lindegger , Andreas Menke , Joerg Scherer , Karin Schwind , Otto Gaa , Gregor Bainczyk , Michael Marquant , Sandro Niederhäuser , Michael Schoemaker , Martin Mueri
IPC分类号： A61B5/145 , G06G7/60
CPC分类号： A61B5/0031 , A61B5/0002 , A61B5/14503 , A61B5/14532 , A61B5/14546 , A61B5/1459 , A61B5/14865 , A61B5/1495 , A61B5/6849 , A61B5/7232 , A61B5/742 , A61B90/98 , A61B2560/0209 , A61B2560/0219 , A61B2560/0481
摘要： The analyte concentration, such as glucose, in a human or animal body is measured with an implantable sensor that generates measurement signals. The measurement signals are compressed through statistical techniques to produced compressed measurement data that can is easier to process and communicate. A base station carries the implantable sensor along with a signal processor, memory, and a transmitter. A display device is also disclosed that can receive the compressed measurement data from the base station for further processing and display.
摘要翻译：使用可产生测量信号的可植入传感器来测量人或动物体内的分析物浓度，例如葡萄糖。测量信号通过统计技术进行压缩，以产生可以更容易处理和通信的压缩测量数据。基站与信号处理器，存储器和发射器一起携带可植入传感器。还公开了可以从基站接收压缩的测量数据以进一步处理和显示的显示装置。

10. 发明授权

US08142721B2 Test strip with slot vent opening 有权
标题翻译：带有排气口的测试条
公开(公告)号：US08142721B2
公开(公告)日：2012-03-27
申请号：US12888990
申请日：2010-09-23
申请人： David W. Burke , Michael Marquant
发明人： David W. Burke , Michael Marquant
IPC分类号： G01N33/48
CPC分类号： G01N33/558 , G01N27/3271 , Y10T156/1059 , Y10T156/1084
摘要： A test strip with a covering layer having a novel slot. The slot divides the inventive covering layer into two parts and provides a vent opening that allows air to escape as fluid enters a cavity or sample receiving chamber formed in the test strip. In preferred embodiments, the covering layer is clear such that the user can see through it and the slot doubles as a “fill line.” The user can thus watch the fluid sample enter the test strip, progress through the capillary cavity, and then stop at the slot or fill-line. This provides positive assurance to the user that the sample size is sufficient and the test strip has been filled properly. The present invention also provides an advantageous method of mass-producing the inventive test strips without having to align the slot or vent opening laterally with respect to the test strips and without having to punch a vent opening. The method is also well suited to mass production by roll processing techniques.
摘要翻译：具有新颖狭缝的覆盖层的测试条。狭槽将本发明的覆盖层分成两部分，并提供通气口，当流体进入形成在测试条中的空腔或样品接收室时，允许空气逸出。在优选实施例中，覆盖层是清晰的，使得用户可以看到它，并且插槽加倍为“填充线”。因此，用户可以观察流体样品进入测试条，通过毛细管腔进行，然后停止在插槽或填充线。这为用户提供了正确的保证，即样品尺寸足够，并且测试条已被正确填充。本发明还提供了批量生产本发明测试条的有利方法，而不必相对于测试条横向对准槽或通风口，而不必冲压排气口。该方法也非常适合通过辊加工技术进行批量生产。

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