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    • 6. 发明申请
    • Test system for determining an analyte in a liquid sample
    • 用于测定液体样品中分析物的测试系统
    • US20050142032A1
    • 2005-06-30
    • US10977379
    • 2004-10-29
    • Joachim HoenesChristine NortmeyerCarina Horn
    • Joachim HoenesChristine NortmeyerCarina Horn
    • G01N33/48G01N33/483G01N33/52G01N33/72G01N33/86G01N33/543
    • G01N33/86G01N33/526G01N33/723
    • A test system for determining an analyte in a liquid sample is provided comprising at least two compartments, wherein the detection reactions necessary to determine the analyte are carried out in a first compartment and an analytical determination of at least one substance which participates in the detection reactions and is different from the analyte, the indicator substance, takes place in a second compartment. The two compartments are separated from one another in a manner which allows the indicator substance to pass into the second compartment and at least partially prevents passage of other substances that could interfere with the analytical determination of the indicator substance in the second compartment. At least one other substance is present in an immobilized form in the second compartment which, as a capture substance, selectively enriches the indicator substance in the second compartment. The indicator substance is not a coenzyme and at the same time the capture substance is not a catalytically inactive coenzyme-binding protein.
    • 提供了用于确定液体样品中的分析物的测试系统,其包括至少两个隔室,其中确定分析物所需的检测反应在第一隔室中进行,并且对参与检测反应的至少一种物质进行分析测定 并且与分析物不同,指示剂物质发生在第二隔室中。 两个隔室以允许指示剂物质进入第二隔室的方式彼此分开,并且至少部分地防止可能干扰第二隔室中指示剂物质的分析确定的其它物质的通过。 至少一种其它物质以固定形式存在于第二隔室中,其作为捕获物质选择性地富集第二隔室中的指示剂物质。 指示物质不是辅酶,同时捕获物质不是催化活性的辅酶结合蛋白。