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1. 发明申请

US20070162106A1 System and methods for endovascular aneurysm treatment 有权
标题翻译：血管内动脉瘤治疗的系统和方法
公开(公告)号：US20070162106A1
公开(公告)日：2007-07-12
申请号：US11482503
申请日：2006-07-07
申请人： Michael Evans , Gwendolyn Watanabe , Amy Lee , Steven Herbowy
发明人： Michael Evans , Gwendolyn Watanabe , Amy Lee , Steven Herbowy
IPC分类号： A61F2/06
CPC分类号： A61F2/958 , A61B17/12118 , A61B17/12136 , A61B17/12195 , A61B2017/1205 , A61F2/06 , A61F2/07 , A61F2/82 , A61F2/90 , A61F2/95 , A61F2002/065 , A61F2002/067 , A61F2002/077 , A61F2220/005 , A61F2220/0058 , A61F2230/0034 , A61F2230/005 , A61F2250/0003 , A61M2025/0002
摘要： Embodiments provide methods and systems for treating aneurysms using filling structures filled with a curable medium. An embodiment of a method comprises positioning at least one double-walled filling structure across the aneurysm and filling the structure(s) with a filling medium so that an outer wall conforms to the inside of the aneurysm and an inner wall forms a generally tubular lumen to provide for blood flow. The lumen is supported with a balloon or other expandable device while and/or after filling. The pressure within the structure and/or in the space between an external wall of the structure and the aneurysm wall is monitored and a flow of the medium into the structure is controlled responsive to the pressure. The pressure can also be used to determine a filling endpoint. The medium is hardened while the lumen remains supported by the balloon. The balloon is then removed after the medium hardens.
摘要翻译：实施例提供了使用填充有可固化介质的填充结构来治疗动脉瘤的方法和系统。方法的一个实施例包括将至少一个双壁填充结构定位在动脉瘤上并用填充介质填充结构，使得外壁符合动脉瘤的内部，并且内壁形成大致管状的内腔提供血流量。管腔在填充时和/或填充后用气囊或其他可扩张装置支撑。监测结构内的压力和/或在结构的外壁和动脉瘤壁之间的空间中的压力，并且响应于压力控制介质流入结构的流动。压力也可用于确定灌装终点。当腔保持气球支撑时，介质硬化。培养基硬化后，取出球囊。

2. 发明申请

US20070150041A1 Methods and systems for aneurysm treatment using filling structures 审中-公开
标题翻译：使用填充结构进行动脉瘤治疗的方法和系统
公开(公告)号：US20070150041A1
公开(公告)日：2007-06-28
申请号：US11444603
申请日：2006-05-31
申请人： Michael Evans , Gwendolyn Watanabe , Amy Lee , Steven Herbowy
发明人： Michael Evans , Gwendolyn Watanabe , Amy Lee , Steven Herbowy
IPC分类号： A61F2/06
CPC分类号： A61B17/12118 , A61B17/12136 , A61B2017/00893 , A61B2017/1205 , A61F2/07 , A61F2/90 , A61F2002/065 , A61F2002/077 , A61F2230/0078 , A61F2250/0067
摘要： Aneurysms are treated by placing a scaffold across an aneurysmal sac to provide a blood flow lumen therethrough. An aneurysmal space surrounding the scaffold is filled with one or more expandable structures which are simultaneously or sequentially expanded to fill the aneurysmal space and reduce the risk of endoluminal leaks and scaffold migration. The expandable structures are typically inflatable and delivered by delivery catheter, optionally with an inflation tube or structure attached to the expandable structure.
摘要翻译：通过将支架放置在动脉瘤囊上以提供通过其的血流腔来治疗动脉瘤。围绕支架的动脉瘤空间填充有一个或多个可扩张结构，其同时或依次扩张以填充动脉瘤空间并降低腔内泄漏和支架迁移的风险。可膨胀结构通常可充气并由输送导管递送，任选地具有连接到可膨胀结构的充气管或结构。

3. 发明申请

US20060212112A1 Graft systems having filling structures supported by scaffolds and methods for their use 有权
标题翻译：具有由支架支撑的填充结构的移植系统及其使用方法
公开(公告)号：US20060212112A1
公开(公告)日：2006-09-21
申请号：US11413460
申请日：2006-04-28
申请人： Michael Evans , Gwendolyn Watanabe , Amy Lee , Steven Herbowy
发明人： Michael Evans , Gwendolyn Watanabe , Amy Lee , Steven Herbowy
IPC分类号： A61F2/06
CPC分类号： A61F2/844 , A61F2/07 , A61F2/90 , A61F2/95 , A61F2002/065 , A61F2002/077 , A61F2230/0034 , A61F2250/0003 , A61F2250/0069
摘要： Aneurysms are treated by filling at least one double-walled filling structure with a curable medium within the aneurysm. The filling structures may be delivered over balloon deployment mechanisms in order to shape and open tubular lumens therethrough. Scaffolds are placed into the tubular lumens in order to help maintain the shape, anchor the filling structures in place, and provide improved blood flow transition into and out of the tubular lumens.
摘要翻译：通过在动脉瘤内填充至少一个具有可固化培养基的双壁填充结构来治疗动脉瘤。填充结构可以在气囊展开机构上传送，以形成和打开通过其中的管状流明。将脚手架放置在管状内腔中，以帮助保持形状，将填充结构锚定在适当位置，并且提供进入和离开管状内腔的改善的血流过渡。

4. 发明授权

US07517352B2 Devices for percutaneous remote endarterectomy 有权
标题翻译：用于经皮远端内膜切除术的装置
公开(公告)号：US07517352B2
公开(公告)日：2009-04-14
申请号：US09820084
申请日：2001-03-27
申请人： Michael Evans , Denise Demarais , Gwendolyn Watanabe , Stephen Leeflang
发明人： Michael Evans , Denise Demarais , Gwendolyn Watanabe , Stephen Leeflang
IPC分类号： A61M29/00
CPC分类号： A61B17/3207 , A61B17/22 , A61B17/221 , A61B17/32002 , A61B17/320725 , A61B17/32075 , A61B17/320783 , A61B2017/00287 , A61B2017/00362 , A61B2017/320004 , A61B2017/320044 , A61B2017/320741 , A61M25/1002 , A61M25/1027 , A61M29/02 , A61M2025/1015 , A61M2025/1088 , A61M2025/109
摘要： The present invention provides devices, systems, methods and kits for the percutaneous removal of unwanted tissue or obstructive matter from body cavities or lumens, particularly from the vasculature. Blood vessels, including the coronary, peripheral and neurovascular circulation, which are narrowed or blocked by atheromatous material or plaque are often treated with traditional endarterectomy procedures. The present invention allows the benefits of such a procedure with an intraluminal approach, particularly a percutaneous approach. Generally, the present invention provides a set of catheters or tools which are percutaneously introduceable to the site of the blockage or occlusion. The tools dissect or cut through the innermost tissue layer of the lumen to an underlying tissue layer. The innermost tissue layer is then stripped away from the underlying layer with the occlusive material thereattached. The detached tissue layer and occlusive material is then removed from the lumen; this may include additional cutting, maceration and removal through mechanical aspiration. In any case, the resulting lumen is free of obstruction.
摘要翻译：本发明提供用于经皮去除不想要的组织或阻塞物质的装置，系统，方法和试剂盒，所述装置，系统，方法和试剂盒用于从体腔或腔，特别是脉管系统中去除。通常使用传统的内膜切除手术治疗包括动脉粥样硬化材料或斑块变窄或阻塞的冠状动脉，周围和神经血管循环的血管。本发明允许使用腔内方法，特别是经皮方法的这种手术的益处。通常，本发明提供一组导管或工具，其经皮可引入阻塞部位或闭塞部位。该工具将内腔的最内层组织切割或切割到下面的组织层。然后将最内侧的组织层从附近的闭塞材料剥离下来的层。然后从管腔移除脱离的组织层和封闭材料; 这可能包括通过机械抽吸进行额外的切割，浸渍和去除。在任何情况下，所得到的内腔没有阻塞。

5. 发明申请

US20060025853A1 Methods and systems for endovascular aneurysm treatment 有权
公开(公告)号：US20060025853A1
公开(公告)日：2006-02-02
申请号：US11187471
申请日：2005-07-22
申请人： Michael Evans , Thomas Howell , Gwendolyn Watanabe , Bhupendra Shah , James McKinley
发明人： Michael Evans , Thomas Howell , Gwendolyn Watanabe , Bhupendra Shah , James McKinley
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2002/075 , A61F2002/077 , A61F2230/0034 , A61F2250/0003
摘要： Aneurysms are treated by filling a double-walled filling structure with a curable medium. The structures may be delivered over balloon deployment mechanisms in order to shape and open tubular lumens therethrough. The filling structures are preferably used in pairs for providing flow into the iliac arteries when treating abdominal aortic aneurysm.

6. 发明申请

US20140338571A1 AGGREGATES 审中-公开
标题翻译：聚集
公开(公告)号：US20140338571A1
公开(公告)日：2014-11-20
申请号：US14368337
申请日：2012-12-21
申请人： Michael EVANS
发明人： Michael Evans
IPC分类号： C04B18/02 , C03C11/00 , C04B18/10 , C04B38/02 , C04B18/06 , C04B18/30 , C03C10/00 , C04B41/50
CPC分类号： C04B18/027 , C03C10/0063 , C03C11/00 , C03C2204/00 , C04B18/023 , C04B18/06 , C04B18/10 , C04B18/305 , C04B28/02 , C04B38/02 , C04B41/5027 , Y02W30/91 , Y02W30/92 , Y02W30/94 , Y02W30/97 , C04B12/04 , C04B14/22 , C04B14/26 , C04B18/04 , C04B18/0463 , C04B18/14 , C04B18/24 , C04B20/1055 , C04B22/0013 , C04B22/16 , C04B24/10 , C04B18/101 , C04B18/103 , C04B18/144
摘要： A method of forming an aggregate. The method comprising forming a green pellet including waste glass and additive(s). The unfired pellets are coated with a refractory material and sintered such that some of the additive/additives breaks down to generate gas which is at least partially retained in the microstructure of the mixture to form pores, the additive/additives so being that upon heating the additive/additives and glass combine to produce glass ceramics.
摘要翻译：一种形成骨料的方法。该方法包括形成包括废玻璃和添加剂的生丸。未烧制的颗粒用耐火材料涂覆并烧结，使得一些添加剂/添加剂分解以产生至少部分地保留在混合物的微结构中以形成孔的气体，添加剂/添加剂使得在加热添加剂/添加剂和玻璃结合生产玻璃陶瓷。

7. 发明授权

US08242115B2 Materials and methods to potentiate cancer treatment 失效
标题翻译：加强癌症治疗的材料和方法
公开(公告)号：US08242115B2
公开(公告)日：2012-08-14
申请号：US11708163
申请日：2007-02-16
申请人： James Halbrook , Edward A. Kesicki , Laurence E. Burgess , Stephen T. Schlachter , Charles T. Eary , Justin G. Schiro , Hongmei Huang , Michael Evans , Yongxin Han
发明人： James Halbrook , Edward A. Kesicki , Laurence E. Burgess , Stephen T. Schlachter , Charles T. Eary , Justin G. Schiro , Hongmei Huang , Michael Evans , Yongxin Han
IPC分类号： C07D311/86 , C07D405/04 , C07D219/06 , C07D219/16 , C07D401/06 , C07D405/12 , C07D471/04 , A61K31/35
CPC分类号： C07D213/40 , A61K45/06 , C07C309/66 , C07D209/36 , C07D211/42 , C07D211/46 , C07D213/50 , C07D213/74 , C07D213/75 , C07D231/12 , C07D233/56 , C07D235/26 , C07D239/48 , C07D249/08 , C07D277/24 , C07D277/54 , C07D279/12 , C07D295/096 , C07D295/112 , C07D295/13 , C07D295/135 , C07D295/155 , C07D295/185 , C07D295/215 , C07D295/30 , C07D307/83 , C07D309/10 , C07D311/30 , C07D333/22 , C07D405/04 , C07D417/12 , C07F9/6533 , C07F9/65785
摘要： Compounds that inhibit DNA-dependent protein kinase, compositions comprising the compounds, methods to inhibit the DNA-PK biological activity, methods to sensitize cells the agents that cause DNA lesions, and methods to potentiate cancer treatment are disclosed.
摘要翻译：公开了抑制DNA依赖性蛋白激酶的化合物，包含该化合物的组合物，抑制DNA-PK生物活性的方法，使细胞致敏引起DNA病变的药剂，以及加强癌症治疗的方法。

8. 发明申请

US20120166087A1 Method of Determining Density of Underground Formations Using Neutron-Gamma Ray Measurements 有权
标题翻译：使用中子伽马射线测量法确定地层密度的方法
公开(公告)号：US20120166087A1
公开(公告)日：2012-06-28
申请号：US13262643
申请日：2010-04-14
申请人： Michael Evans
发明人： Michael Evans
IPC分类号： G06F19/00 , G01V5/10
CPC分类号： G01V5/101
摘要： A method of determining the density of an underground formation surrounding a borehole from measurement of gamma rays arising from irradiation of the formation by a nuclear source in a tool body located in the borehole, and measurement of gamma-ray flux in the tool body at two different detector spacings from the source, the method comprising determining a substantially straight-line relationship between gamma-ray flux measurements at each different spacing with respect to the density of the formation for a tool body with no standoff; determining a relationship defining the deviation with respect to tool standoff of the density determined from the measured gamma-ray flux measurements at the two different detector spacings from the density calculated from the straight line relationships; and for a given pair of gamma-ray flux measurements at the different detector spacings, determining the intersection of the relationship defining the deviation with the straight line relationship so as to indicate the density of the formation surrounding the bore-hole; wherein the source is a neutron source and the gamma rays measured in the too! body are neutron-induced gamma rays resulting from neutron irradiation of the formation.
摘要翻译：一种通过从位于钻孔中的工具体中的核源照射产生的伽马射线的测量来确定钻孔周围地下地层的密度的方法，以及在两个工具体中测量γ射线通量与源不同的检测器间隔，该方法包括确定在每个不同间隔处的伽马射线通量测量值相对于没有间隙的工具主体的密度的基本上的直线关系; 确定相对于从两个不同检测器间隔处测量的伽马射线通量测量值与从直线关系计算的密度确定的密度的刀具间隔的界定的关系; 并且对于在不同检测器间距处的给定的一对伽马射线通量测量，确定限定偏差的关系与直线关系的交点，以指示围绕钻孔的地层的密度; 其中源是中子源，伽马射线也在测量中！身体是由地层的中子照射产生的中子诱导的γ射线。

9. 发明授权

US08185280B2 Method and apparatus for shifting gears in transmissions 有权
标题翻译：用于在变速器中换档的方法和装置
公开(公告)号：US08185280B2
公开(公告)日：2012-05-22
申请号：US12003004
申请日：2007-12-19
申请人： Michael Evans , Simon Conway
发明人： Michael Evans , Simon Conway
IPC分类号： G06F17/00
CPC分类号： F16H61/462 , F16H47/02 , F16H61/0403 , F16H61/47 , F16H2061/047 , F16H2306/44 , F16H2306/48
摘要： A method of changing from a first gear position to a second gear position of a transmission arrangement is disclosed. The arrangement includes a rotatable transmission member, a hydrostatic continuously variable transmission coupled to the transmission member and operable to rotate the transmission member at a first speed, a controller configured to control operation of the hydrostatic continuously variable transmission, and a gear apparatus coupled to the transmission member and configured to be shiftable between at least the first gear position and the second gear position. The method includes controlling the hydrostatic continuously variable transmission, using the controller, to rotate the transmission member at the first speed, and shifting the gear apparatus from the first gear position to the second gear position while the transmission member is rotating at, or converging with, the first speed.
摘要翻译：公开了一种从变速器装置的第一档位改变到第二档位的方法。该装置包括可旋转的传动构件，连接到传动构件并且可操作以以第一速度旋转传动构件的静压无级变速传动装置，配置成控制静液压无级变速器的操作的控制器，以及耦合到传动构件，并且构造成能够在至少第一档位与第二档位之间移动。该方法包括使用控制器控制静液压无级变速器，以一速度旋转变速器构件，并且在传动构件在第一档位转动或与其同步时将齿轮装置从第一档位移动到第二档位，第一速。

10. 发明授权

US07566272B2 Gaming device with offer/acceptance game having offer chosen from multiple formed offers 失效
标题翻译：具有提供/接受游戏的游戏装置具有从多个成形优惠中选择的优惠
公开(公告)号：US07566272B2
公开(公告)日：2009-07-28
申请号：US11853603
申请日：2007-09-11
申请人： Peter Gerrard , Michael Evans , Dov L. Randall , Aaron T. Jones
发明人： Peter Gerrard , Michael Evans , Dov L. Randall , Aaron T. Jones
IPC分类号： A63F9/24
CPC分类号： G07F17/3262 , G07F17/32
摘要： A primary or secondary game for a gaming device. In one embodiment, the player is provided up to three picks, i.e., picks three contestants. The first two contestants both form potential award offers. The game then provides the greater of the two potential award offers to the player as an initial offer. This initial sequence alternatives includes more than two picks, contestants and potential offers. The offer acceptance feature arises after the initial offer. The player must decide whether to keep the initial offer or forego that offer for a final offer. If the player keeps the offer the game provides that initial offer to the player and ends if the player rejects that initial offer, the game proceeds to build a third and final offer, which is then provided to the player automatically.
摘要翻译：游戏设备的主要或次要游戏。在一个实施例中，玩家最多提供三个选择，即选择三个选手。前两名参赛者均形成潜在奖项。游戏然后提供两个潜在的奖励优惠给玩家作为初始报价。这个初始序列替代方案包括两个以上的选择，参赛者和潜在的优惠。报价接受功能在初始报价后出现。玩家必须决定是否保留最终报价或放弃最终报价的报价。如果玩家保持优惠，则游戏向玩家提供初始报价，并且如果玩家拒绝该初始报价，则结束游戏，游戏继续建立第三和最终报价，然后自动提供给玩家。

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