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1. 发明申请

US20100137960A1 IMPLANTABLE NEUROSTIMULATORS HAVING REDUCED POCKET STIMULATION 审中-公开
标题翻译：具有减少口袋刺激的可植入神经细胞
公开(公告)号：US20100137960A1
公开(公告)日：2010-06-03
申请号：US12629814
申请日：2009-12-02
申请人： Michael A. Moffitt , Dongchul Lee , Kerry Bradley
发明人： Michael A. Moffitt , Dongchul Lee , Kerry Bradley
IPC分类号： A61N1/00
CPC分类号： A61N1/36175 , A61N1/08 , A61N1/36185 , A61N1/372 , A61N1/37205 , A61N1/3756
摘要： Neurostimulators and methods of using neurostimulators are provided. The neurostimulator is implanted within a tissue pocket of a patient, and electrical energy is conveyed from the neurostimulator to stimulate a target tissue site remote from the tissue pocket. The neurostimulator has a case with which one or more electrodes are associated. The electrical energy is returned to the electrode(s) in a manner that prevents, or at least reduces, pocket stimulation that may otherwise occur due to the return of electrical energy to the case of the neurostimulator.
摘要翻译：提供神经刺激器和使用神经刺激器的方法。将神经刺激器植入患者的组织袋中，并且电能从神经刺激器传送以刺激远离组织袋的靶组织部位。神经刺激器具有与一个或多个电极相关联的情况。电能以防止或至少减少由于电能返回到神经刺激器的情况而可能发生的口袋刺激的方式返回到电极。

2. 发明授权

US08494626B2 Implantable neurostimulators having reduced pocket stimulation 有权
标题翻译：具有减少口袋刺激的植入式神经刺激器
公开(公告)号：US08494626B2
公开(公告)日：2013-07-23
申请号：US12630591
申请日：2009-12-03
申请人： Michael A. Moffitt , Dongchul Lee
发明人： Michael A. Moffitt , Dongchul Lee
IPC分类号： A61N1/00
CPC分类号： A61N1/36175 , A61N1/08 , A61N1/36185 , A61N1/372 , A61N1/37205 , A61N1/3756
摘要： Neurostimulators and methods of using neurostimulators are provided. The neurostimulator is implanted within a tissue pocket of a patient, and electrical energy is conveyed from the neurostimulator to stimulate a target tissue site remote from the tissue pocket. The neurostimulator has a case with which one or more electrodes are associated. The electrical energy is returned to the electrode(s) in a manner that prevents, or at least reduces, pocket stimulation that may otherwise occur due to the return of electrical energy to the case of the neurostimulator.
摘要翻译：提供神经刺激器和使用神经刺激器的方法。将神经刺激器植入患者的组织袋中，并且电能从神经刺激器传送以刺激远离组织袋的靶组织部位。神经刺激器具有与一个或多个电极相关联的情况。电能以防止或至少减少由于电能返回到神经刺激器的情况而可能发生的口袋刺激的方式返回到电极。

3. 发明申请

US20100137962A1 IMPLANTABLE NEUROSTIMULATORS HAVING REDUCED POCKET STIMULATION 审中-公开
公开(公告)号：US20100137962A1
公开(公告)日：2010-06-03
申请号：US12630633
申请日：2009-12-03
申请人： Michael A. Moffitt , Dongchul Lee
发明人： Michael A. Moffitt , Dongchul Lee
IPC分类号： A61N1/00
CPC分类号： A61N1/36175 , A61N1/08 , A61N1/36185 , A61N1/372 , A61N1/37205 , A61N1/3756
摘要： Neurostimulators and methods of using neurostimulators are provided. The neurostimulator is implanted within a tissue pocket of a patient, and electrical energy is conveyed from the neurostimulator to stimulate a target tissue site remote from the tissue pocket. The neurostimulator has a case with which one or more electrodes are associated. The electrical energy is returned to the electrode(s) in a manner that prevents, or at least reduces, pocket stimulation that may otherwise occur due to the return of electrical energy to the case of the neurostimulator.

4. 发明授权

US09393422B2 Implantable neurostimulators having reduced pocket stimulation 有权
公开(公告)号：US09393422B2
公开(公告)日：2016-07-19
申请号：US12630633
申请日：2009-12-03
申请人： Michael A. Moffitt , Dongchul Lee
发明人： Michael A. Moffitt , Dongchul Lee
IPC分类号： A61N1/375 , A61N1/36 , A61N1/08 , A61N1/372
CPC分类号： A61N1/36175 , A61N1/08 , A61N1/36185 , A61N1/372 , A61N1/37205 , A61N1/3756
摘要： Neurostimulators and methods of using neurostimulators are provided. The neurostimulator is implanted within a tissue pocket of a patient, and electrical energy is conveyed from the neurostimulator to stimulate a target tissue site remote from the tissue pocket. The neurostimulator has a case with which one or more electrodes are associated. The electrical energy is returned to the electrode(s) in a manner that prevents, or at least reduces, pocket stimulation that may otherwise occur due to the return of electrical energy to the case of the neurostimulator.

5. 发明申请

US20100137961A1 IMPLANTABLE NEUROSTIMULATORS HAVING REDUCED POCKET STIMULATION 有权
公开(公告)号：US20100137961A1
公开(公告)日：2010-06-03
申请号：US12630591
申请日：2009-12-03
申请人： Michael A. Moffitt , Dongchul Lee
发明人： Michael A. Moffitt , Dongchul Lee
IPC分类号： A61N1/00
CPC分类号： A61N1/36175 , A61N1/08 , A61N1/36185 , A61N1/372 , A61N1/37205 , A61N1/3756
摘要： Neurostimulators and methods of using neurostimulators are provided. The neurostimulator is implanted within a tissue pocket of a patient, and electrical energy is conveyed from the neurostimulator to stimulate a target tissue site remote from the tissue pocket. The neurostimulator has a case with which one or more electrodes are associated. The electrical energy is returned to the electrode(s) in a manner that prevents, or at least reduces, pocket stimulation that may otherwise occur due to the return of electrical energy to the case of the neurostimulator.

6. 发明授权

US09504818B2 Multiple tunable central cathodes on a paddle for increased medial-lateral and rostral-caudal flexibility via current steering 有权
公开(公告)号：US09504818B2
公开(公告)日：2016-11-29
申请号：US12204170
申请日：2008-09-04
申请人： Michael Moffitt , Dongchul Lee , Kerry Bradley , David K. L. Peterson
发明人： Michael Moffitt , Dongchul Lee , Kerry Bradley , David K. L. Peterson
IPC分类号： A61N1/34 , A61N1/05 , A61N1/36
CPC分类号： A61N1/0551 , A61N1/0553 , A61N1/36071
摘要： A neurostimulation paddle lead, method of neurostimulation, and neurostimulation system are provided. The neurostimulation paddle lead carries a plurality of electrodes comprising at least four columns of electrodes having a spacing between two inner electrode columns less than a spacing between the inner electrode columns and adjacent outer electrode columns. The inner electrode columns may also be longitudinally offset from the outer electrode columns. The methods and neurostimulation systems steer current between the electrodes to modify a medial-lateral electrical field created adjacent spinal cord tissue.

7. 发明申请

US20120330391A1 SYSTEM AND METHOD FOR SPINAL CORD STIMULATION TO TREAT MOTOR DISORDERS 有权
标题翻译：用于脊髓刺激治疗电机障碍的系统和方法
公开(公告)号：US20120330391A1
公开(公告)日：2012-12-27
申请号：US13529906
申请日：2012-06-21
申请人： Kerry Bradley , Dongchul Lee
发明人： Kerry Bradley , Dongchul Lee
IPC分类号： A61N1/05
CPC分类号： A61N1/0551 , A61N1/0553 , A61N1/36067 , A61N1/36171 , A61N1/36175
摘要： A method for using spinal cord stimulation to treat symptoms of motor disorders includes implanting a stimulation lead within a ventral portion of the epidural space. The lead is implanted with at least a portion of the electrodes facing the spinal cord. In a method for providing therapy to a patient suffering from a motor disorder, electrical stimulation energy is applied to at least one ventral column nerve fiber through the implanted stimulation lead. A peripheral region of the patient's body exhibits the symptoms of the motor disorder, and the ventral column nerve fiber to which the stimulation is applied innervates that peripheral region.
摘要翻译：使用脊髓刺激来治疗运动障碍症状的方法包括将刺激引线植入硬膜外腔的腹侧部分。植入铅的至少一部分电极面向脊髓。在向患有运动障碍的患者提供治疗的方法中，通过植入的刺激引线向至少一个腹侧神经纤维施加电刺激能量。患者身体的周边区域表现出运动障碍的症状，并且施加刺激的腹侧柱神经纤维支配该外周区域。

8. 发明申请

US20100125314A1 SYSTEM AND METHOD FOR ADJUSTING AUTOMATIC PULSE PARAMETERS TO SELECTIVELY ACTIVATE NERVE FIBERS 有权
标题翻译：用于调整自动脉冲参数以选择性激活神经纤维的系统和方法
公开(公告)号：US20100125314A1
公开(公告)日：2010-05-20
申请号：US12606050
申请日：2009-10-26
申请人： Kerry Bradley , Bradley Hershey , Dongchul Lee
发明人： Kerry Bradley , Bradley Hershey , Dongchul Lee
IPC分类号： A61N1/08
CPC分类号： A61N1/36192 , A61N1/36071 , A61N1/37247
摘要： A method of stimulating nerve tissue, a tissue stimulation system, and an external control device are provided. The method, system, and control device causes an electrical stimulus to be applied to at least one electrode adjacent the nerve tissue of a patient. The applied electrical stimulus comprises a plurality of pulses defined by a pulse width value and an amplitude value. The pulse amplitude value is increased (e.g., manually), and the pulse width value is automatically decreased in response to increasing the pulse amplitude value in a manner that increases the intensity of the applied electrical stimulus. Alternatively, the pulse width value may be decreased (e.g., manually), and the pulse amplitude value automatically increased in response to decreasing the pulse width value in a manner that increases the intensity of the applied electrical stimulus.
摘要翻译：提供刺激神经组织，组织刺激系统和外部控制装置的方法。该方法，系统和控制装置使得电刺激被施加到邻近患者神经组织的至少一个电极。所施加的电刺激包括由脉冲宽度值和振幅值定义的多个脉冲。脉冲幅度值增加（例如，手动），并且响应于以增加所施加的电刺激的强度的方式增加脉冲幅值来自动减小脉冲宽度值。或者，可以减小脉冲宽度值（例如，手动地），并且响应于以增加所施加的电刺激的强度的方式减小脉冲宽度值，脉冲振幅值自动增加。

9. 发明申请

US20090024189A1 USE OF STIMULATION PULSE SHAPE TO CONTROL NEURAL RECRUITMENT ORDER AND CLINICAL EFFECT 有权
标题翻译：刺激脉冲形状的使用来控制神经激励和临床效果
公开(公告)号：US20090024189A1
公开(公告)日：2009-01-22
申请号：US12175758
申请日：2008-07-18
申请人： Dongchul Lee , Michael Moffitt , Christopher Ewan Gillespie , Kerry Bradley
发明人： Dongchul Lee , Michael Moffitt , Christopher Ewan Gillespie , Kerry Bradley
IPC分类号： A61N1/36
CPC分类号： A61N1/36146 , A61N1/36003 , A61N1/36007 , A61N1/36017 , A61N1/36036 , A61N1/36046 , A61N1/3605 , A61N1/3606 , A61N1/36135 , A61N1/37247 , A61N1/378 , A61N1/3787 , A61N1/3906
摘要： A method, electrical tissue stimulation system, and programmer for providing therapy to a patient are provided. Electrodes are placed adjacent tissue (e.g., spinal cord tissue) of the patient, electrical stimulation energy is delivered from the electrodes to the tissue in accordance with a defined waveform, and a pulse shape of the defined waveform is modified, thereby changing the characteristics of the electrical stimulation energy delivered from the electrode(s) to the tissue. The pulse shape may be modified by selecting one of a plurality of different pulse shape types or by adjusting a time constant of the pulse shape.
摘要翻译：提供了一种用于向患者提供治疗的方法，电组织刺激系统和程序员。电极被放置在患者的组织（例如，脊髓组织）的附近，电刺激能量根据定义的波形从电极传送到组织，并且限定波形的脉冲形状被修改，从而改变从电极传递到组织的电刺激能量。可以通过选择多种不同的脉冲形状类型之一或通过调整脉冲形状的时间常数来修改脉冲形状。

10. 发明授权

US09463323B2 Spatially selective nerve stimulation in high-frequency nerve conduction block and recruitment 有权
标题翻译：空间选择性神经刺激在高频神经传导阻滞和招募
公开(公告)号：US09463323B2
公开(公告)日：2016-10-11
申请号：US12819107
申请日：2010-06-18
申请人： Dongchul Lee , Bradley Hershey , Kerry Bradley
发明人： Dongchul Lee , Bradley Hershey , Kerry Bradley
IPC分类号： A61N1/00 , A61N1/36 , A61N1/06
CPC分类号： A61N1/36167 , A61N1/06 , A61N1/36007 , A61N1/36071
摘要： A method of providing therapy to a patient using at least one electrode is provided. The patient has a neural tissue region that is relatively close to the at least one electrode, and a neural tissue region that is relatively far from the at least one electrode. The method comprises conveying time-varying electrical energy from the electrode(s) into the relatively close and far neural tissue regions, wherein the electrical energy has a frequency and amplitude that blocks stimulation of the relatively close neural tissue region, while stimulating the relatively far neural tissue region.
摘要翻译：提供了使用至少一个电极向患者提供治疗的方法。患者具有相对靠近至少一个电极的神经组织区域和相对远离至少一个电极的神经组织区域。该方法包括将时间变化的电能从电极传送到相对靠近和远的神经组织区域，其中电能具有阻止刺激相对较近的神经组织区域的频率和幅度，同时刺激相对较远神经组织区域。

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