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1. 发明授权

US6071505A Cationic cellulose derivatives of controlled charge density useful in cosmetic preparations 失效
标题翻译：具有控制电荷密度的阳离子纤维素衍生物可用于化妆品制剂
公开(公告)号：US6071505A
公开(公告)日：2000-06-06
申请号：US286814
申请日：1999-04-06
申请人： Melissa A. Manuszak-Guerrini , Doris A. Culberson , William H. Daly
发明人： Melissa A. Manuszak-Guerrini , Doris A. Culberson , William H. Daly
IPC分类号： A01N43/16 , A61K8/73 , A61Q5/02 , A61Q5/06 , A61Q5/12 , C08B11/193 , C08B11/20 , C08B15/06 , A61K7/06 , C07H5/04 , C07H11/02 , C08B15/04
CPC分类号： A61Q5/02 , A01N43/16 , A61K8/731 , A61Q5/06 , A61Q5/12 , C08B11/193 , C08B11/20 , C08B15/06 , A61K2800/5426
摘要： Water-soluble quaternary ammonium cellulosic derivatives of controlled charge density are disclosed. These derivatives are useful in cosmetic preparations, such as hair and skin formulations, for example hair conditioners. These quaternized cellulosic derivatives are useful as thickeners, conditioners, film formers, fixatives, emulsifiers, or additives in hair or skin formulations to improve combing, manageability, body, curl retention, moisture resistance, and binding of ingredients to keratin. Compared to existing agents, these compounds have improved temperature stability, improved interactions with surfactants (such as in shampoos), improved binding to keratin, improved mechanical properties, and can mend split ends on hair. A major advantage of these compounds is that they may be applied to hair directly from an aqueous solution, and do not require a volatile organic compound solvent as carrier. Alternatively, smaller amounts of VOC's may be used than is the case in current products, to improve drying times for the formulations. The compounds are also useful as antistatic agents, bactericides, flocculating agents, and as drug binding or drug delivery agents.
摘要翻译：公开了具有受控电荷密度的水溶性季铵纤维素衍生物。这些衍生物可用于化妆品制剂，例如头发和皮肤制剂，例如头发调理剂。这些季铵化的纤维素衍生物可用作毛发或皮肤制剂中的增稠剂，调理剂，成膜剂，固定剂，乳化剂或添加剂，以改善组合，可管理性，身体，卷曲保留性，耐湿性和成分与角蛋白的结合。与现有的试剂相比，这些化合物具有改善的温度稳定性，改善与表面活性剂的相互作用（如洗发剂），改善的与角蛋白的结合，改进的机械性能，以及修补头发上的分叉端。这些化合物的主要优点是它们可以直接从水溶液中施用于毛发，并且不需要挥发性有机化合物溶剂作为载体。或者，可以使用比当前产品更小量的VOC，以改善制剂的干燥时间。这些化合物也可用作抗静电剂，杀菌剂，絮凝剂，以及药物结合或药物递送剂。

2. 发明授权

US5981737A Cationic cellulose derivatives of controlled charge density useful in cosmetic preparations 失效
公开(公告)号：US5981737A
公开(公告)日：1999-11-09
申请号：US822987
申请日：1997-03-21
申请人： Melissa A. Manuszak-Guerrini , Doris A. Culberson , William H. Daly
发明人： Melissa A. Manuszak-Guerrini , Doris A. Culberson , William H. Daly
IPC分类号： A01N43/16 , A61K8/73 , A61Q5/02 , A61Q5/06 , A61Q5/12 , C08B11/193 , C08B11/20 , C08B15/06
CPC分类号： A61Q5/02 , A01N43/16 , A61K8/731 , A61Q5/06 , A61Q5/12 , C08B11/193 , C08B11/20 , C08B15/06 , A61K2800/5426
摘要： Water-soluble quaternary ammonium cellulosic derivatives of controlled charge density are disclosed. These derivatives are useful in cosmetic preparations, such as hair and skin formulations, for example hair conditioners. These quaternized cellulosic derivatives are useful as thickeners, conditioners, film formers, fixatives, emulsifiers, or additives in hair or skin formulations to improve combing, manageability, body, curl retention, moisture resistance, and binding of ingredients to keratin. Compared to existing agents, these compounds have improved temperature stability, improved interactions with surfactants (such as in shampoos), improved binding to keratin, improved mechanical properties, and can mend split ends on hair. A major advantage of these compounds is that they may be applied to hair directly from an aqueous solution, and do not require a volatile organic compound solvent as carrier. Alternatively, smaller amounts of VOC's may be used than is the case in current products, to improve drying times for the formulations. The compounds are also useful as antistatic agents, bactericides, flocculating agents, and as drug binding or drug delivery agents.

3. 发明授权

US06306835B1 Biocidal chitosan derivatives 失效
标题翻译：杀生物壳聚糖衍生物
公开(公告)号：US06306835B1
公开(公告)日：2001-10-23
申请号：US09154365
申请日：1998-09-16
申请人： William H. Daly , Melissa A. Manuszak-Guerrini
发明人： William H. Daly , Melissa A. Manuszak-Guerrini
IPC分类号： A01N4304
CPC分类号： C11D3/48 , A01N43/16 , A61K8/736 , A61K31/702 , A61K31/722 , A61K2800/524 , A61K2800/5426 , A61Q5/00 , A61Q19/00 , C11D3/227 , Y02A50/473 , A01N25/34 , A01N25/10 , A01N2300/00
摘要： 3-trimethylammonium-2-hydroxypropyl-N-chitosan (CHI-Q188) and related chitosan derivatives exhibit antimicrobial activity at concentrations as low as 10-20 &mgr;g/mL, an order of magnitude lower than the concentrations at which any previous chitosan derivative has been reported to exhibit antimicrobial activity. These compounds may be used as preservatives in cosmetic formulations, and as antimicrobial pharmaceutical agents.
摘要翻译： 3-三甲基铵-2-羟丙基-N-壳聚糖（CHI-Q188）和相关壳聚糖衍生物在低至10-20ug / mL的浓度下表现出抗微生物活性，其量低于任何先前的壳聚糖衍生物具有的浓度据报道具有抗菌活性。这些化合物可以用作化妆品制剂中的防腐剂，也可用作抗微生物药剂。

4. 发明授权

US5114275A Process and waste pit liner for improved hydrophobic waste storage 失效
标题翻译：过程和废物坑衬垫，用于改善疏水性废物储存
公开(公告)号：US5114275A
公开(公告)日：1992-05-19
申请号：US662388
申请日：1991-02-26
申请人： Philip W. West , William H. Daly
发明人： Philip W. West , William H. Daly
IPC分类号： B09B1/00 , C02F11/00 , C04B28/00 , C04B28/02 , E02D31/00
CPC分类号： E02D31/00 , B09B1/00 , C02F11/008 , C04B28/001 , C04B28/02 , C04B2103/0052 , C04B2111/00775 , Y10S106/90
摘要： A process for improved hydrophobic waste storage is described wherein a latex comprising a preformed, high molecular weight polymer having a high affinity for hydrophobic liquids, is sprayed on the waste prior to admixing an inorganic matrix material. Alternately, a liner for use in a waste pit which is to contain hydrophobic waste liquids or concentrated aqueous salt solutions is produced in situ by blending and compacting a latex comprising a hydrophobic polymer and clay onto the surface of the waste pit.
摘要翻译：描述了一种用于改进疏水性废物储存的方法，其中包含预先形成的对疏水性液体具有高亲和性的高分子量聚合物的胶乳在混合无机基质材料之前喷洒在废物上。或者，通过将包含疏水性聚合物和粘土的胶乳混合并压实到废物坑的表面上，原位生产用于包含疏水性废液或浓缩盐水溶液的废物坑中的衬垫。

5. 发明授权

US6103866A X-ray lithography resists 失效
标题翻译： X射线光刻抗蚀剂
公开(公告)号：US6103866A
公开(公告)日：2000-08-15
申请号：US268506
申请日：1999-03-11
申请人： Jack D. Davies , William H. Daly
发明人： Jack D. Davies , William H. Daly
IPC分类号： G03F7/039 , G03F7/20 , C08G75/20
CPC分类号： G03F7/2039 , G03F7/039 , Y10S430/168
摘要： Poly (diene sulfones) have superior properties as X-ray resists. Many poly (diene sulfones) have an X-ray sensitivity below about 50 mJ/cm.sup.2, and a glass transition temperature above about 70.degree. C. A preferred X-ray resist is poly (1,3-hexadiene sulfone). A method of synthesizing poly (diene sulfones) is disclosed, in which a diene monomer is dissolved in a molar excess of a nitroalkane at low temperature, for example in a molar excess of dried 2-nitropropane in a -78.degree. C. dry ice/acetone bath, and reacted with a molar excess of sulfur dioxide in the presence of a free radical initiator such as tert-butyl-hydroperoxide.
摘要翻译：聚（二烯砜）具有优异的性能，如X射线抗蚀剂。许多聚（二烯砜）的X射线敏感度低于约50mJ / cm 2，玻璃化转变温度高于约70℃。优选的X射线抗蚀剂是聚（1,3-己二烯砜）。公开了一种合成聚（二烯砜）的方法，其中二烯单体在低温下溶解在摩尔过量的硝基烷烃中，例如在-78℃的干冰中以摩尔过量的干燥的2-硝基丙烷 /丙酮浴，并在自由基引发剂如叔丁基过氧化氢的存在下与摩尔过量的二氧化硫反应。

6. 发明授权

US06013738A Composition and method for chiral separations 失效
标题翻译：手性分离的组成和方法
公开(公告)号：US06013738A
公开(公告)日：2000-01-11
申请号：US154377
申请日：1998-09-16
申请人： William H. Daly , Drew S. Poche , Stefan J. Thibodeaux , Isiah M. Warner
发明人： William H. Daly , Drew S. Poche , Stefan J. Thibodeaux , Isiah M. Warner
IPC分类号： B01D61/16 , B01D61/38 , C08G69/10 , C08F283/04
CPC分类号： B01D61/16 , B01D61/007 , B01D61/145 , B01D61/38 , C08G69/10 , B01D2311/04
摘要： Polymers are disclosed that are useful in performing chiral separations. A synthetic scheme for producing the novel polymers is also disclosed. The alkyl side chains of poly(.gamma.-alkyl-.alpha.,L-glutamates) have been altered, allowing the facile substitution of the side chains with pendent functional groups. The compounds may be used as a stationary-phase or pseudo-stationary phase in separation techniques such as high performance liquid chromatography, or electrokinetic capillary chromatography. The novel compounds are water-soluble or water-swellable, and are particularly useful in separations of stereoisomers.
摘要翻译：公开了可用于进行手性分离的聚合物。还公开了用于生产新型聚合物的合成方案。聚（γ-烷基-α，L-谷氨酸）的烷基侧链已被改变，允许用侧链官能团容易地取代侧链。在高效液相色谱法或电动毛细管色谱法等分离技术中，化合物可用作固定相或假固定相。新型化合物是水溶性或水溶胀性的，并且在立体异构体的分离中特别有用。

7. 发明授权

US4384113A Stabilization of alkali polysaccharides 失效
标题翻译：碱性多糖的稳定化
公开(公告)号：US4384113A
公开(公告)日：1983-05-17
申请号：US361013
申请日：1982-03-23
申请人： William H. Daly
发明人： William H. Daly
IPC分类号： C08B1/08 , C08B1/06 , C08B11/00
CPC分类号： C08B11/00 , C08B1/06
摘要： Improved basic polysaccharides are prepared by contacting a polysaccharide with a tetravalent onium salt such as tetramethylammonium chloride prior to contacting it with a strong base such as sodium hydroxide. Polysaccharide derivatives having a greater degree and uniformity of substitution are prepared from such improved basic polysaccharides.
摘要翻译：在将其与强碱如氢氧化钠接触之前，通过使多糖与四价鎓盐如四甲基氯化铵接触来制备改进的碱性多糖。由这种改良的碱性多糖制备具有更高的取代度和均匀性的多糖衍生物。

8. 发明申请

US20080281000A1 Hydrophobic Polysaccharide Derivatives 审中-公开
标题翻译：疏水多糖衍生物
公开(公告)号：US20080281000A1
公开(公告)日：2008-11-13
申请号：US12065846
申请日：2006-09-06
申请人： William H. Daly , Ahmad A. Bahamdan
发明人： William H. Daly , Ahmad A. Bahamdan
IPC分类号： C08B37/00 , C08B37/08 , C08B11/00 , A61K47/26 , A61P27/02 , C09K8/68 , C08B31/08
CPC分类号： C08B37/0096
摘要： Novel cross-linked gels comprised of alkoxyetheramides grafted to polysaccharides that have superior viscosity properties have been made. By controlling the chain length of the alkoxyetheramides and the hydrophobic nature of the gel, these materials are ideal for many uses such as in hydraulic fracturing of oil-bearing geological formations, in the paint and dye industries, as dispersants, in personal care products and for carriers in controlled drug delivery.
摘要翻译：已经制备了由接枝到具有优异粘度特性的多糖的烷氧基醚酰胺构成的新型交联凝胶。通过控制烷氧基醚酰胺的链长和凝胶的疏水性，这些材料对于许多用途是理想的，例如在含油地质构造的水力压裂中，在油漆和染料工业中，作为分散剂，个人护理产品和用于控制药物递送的载体。

9. 发明授权

US5922518A X-ray lithography resists 失效
公开(公告)号：US5922518A
公开(公告)日：1999-07-13
申请号：US757218
申请日：1996-11-27
申请人： Jack D. Davies , William H. Daly
发明人： Jack D. Davies , William H. Daly
IPC分类号： G03F7/039 , G03F7/20 , G03C5/16
CPC分类号： G03F7/2039 , G03F7/039 , Y10S430/168
摘要： Poly (diene sulfones) have superior properties as X-ray resists. Many poly (diene sulfones) have an X-ray sensitivity below about 50 mJ/cm.sup.2, and a glass transition temperature above about 70.degree. C. A preferred X-ray resist is poly (1,3-hexadiene sulfone). A method of synthesizing poly (diene sulfones) is disclosed, in which a diene monomer is dissolved in a molar excess of a nitroalkane at low temperature, for example in a molar excess of dried 2-nitropropane in a -78.degree. C. dry ice/acetone bath, and reacted with a molar excess of sulfur dioxide in the presence of a free radical initiator such as tert-butyl-hydroperoxide.

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