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    • 1. 发明授权
    • Specific detoxification of urushiol with manganese salts
    • 漆酚与锰盐的特异性解毒
    • US5443847A
    • 1995-08-22
    • US92129
    • 1993-07-15
    • Philip W. West
    • Philip W. West
    • A61K31/28A61K33/32
    • A61K31/28A61K33/32Y10S424/06Y10S514/862
    • A method for treating rhus dermatitis caused by exposure to urushiol is provided, comprising the step of topically applying a therapeutically effective amount of a soluble manganese salt to the affected area of the skin. The manganese compound penetrates the pores of the skin and acts a chelating agent on the urushiol molecule, deactivating its toxicity. A detoxification agent for urushiol is also provided, comprising a composition containing a soluble salt of manganese, such as an aqueous or alcohol solution, wherein the weight percent of manganese in said composition is a therapeutically effective amount, such as between 0.01% and 10.0% manganese. The detoxification agent is also useful as a means of preventing rhus dermatitis when applied to the skin in an appropriate base.
    • 提供了一种用于治疗由暴露于漆酚引起的皮肤炎的方法,包括将治疗有效量的可溶性锰盐局部施用于皮肤受影响的区域的步骤。 锰化合物渗透皮肤的孔,并在漆酚分子上起螯合作用,使其毒性失活。 还提供了用于漆酚的解毒剂,其包含含有可溶性锰盐的组合物,例如水溶液或醇溶液,其中所述组合物中锰的重量百分数为治疗有效量,例如0.01%至10.0% 锰。 解毒剂也可用作在适当的基础中施用于皮肤时预防根皮炎的手段。
    • 3. 发明授权
    • Personal monitoring device, or dosimeter, for measuring exposure of
personnel to organic vapors
    • 个人监护装置或剂量计,用于测量人员对有机蒸气的暴露
    • US4040805A
    • 1977-08-09
    • US735010
    • 1976-10-22
    • Leonard H. NelmsKenneth D. ReisznerPhilip W. West
    • Leonard H. NelmsKenneth D. ReisznerPhilip W. West
    • G01N17/00G01N30/00G01N33/00B01D13/00
    • G01N33/0027G01N30/00
    • A personal monitoring device, dosimeter, or badge-like apparatus for measuring the exposure of personnel to pollutant toxic organic vaporous materials, notably vinyl chloride, comprised of a body portion provided with a relatively shallow top cavity, or cup-like member completely filled with an adsorbent, absorbent or reactive material, preferably activated carbon, covered, closed and physically held in place by a contiguous, thin non-porous membrane, permeable to the organic vaporous materials, notably vinyl chloride. The polluting toxic material, e.g., vinyl chloride, permeates and is transported through the membrane and is then adsorbed on the activated carbon at a rate proportional to the external concentration during the period of exposure and is subsequently removed for analysis, as by gas chromatography. The device is simple in construction, easy to use, insensitive to temperature and humidity effects, and free of other possible interferences. The device is ideally suited to personal monitoring programs required by OSHA regulations, and the analytical data obtained represents a time-weighted-average exposure which requires no further data evaluations.
    • 用于测量人员暴露于污染有毒有机气态材料(特别是氯乙烯)的个人监测装置,剂量计或类似徽章的装置,其包括设置有较浅顶部空腔的主体部分或完全填充有 吸附剂,吸收剂或反应性材料,优选活性炭,被可渗透有机气态材料,特别是氯乙烯的邻接的薄无孔膜覆盖,闭合并物理保持就位。 污染有毒的物质,例如氯乙烯,渗透并通过膜输送,然后在暴露期间以与外部浓度成比例的比例吸附在活性炭上,随后通过气相色谱法将其去除以进行分析。 该设备结构简单,使用方便,对温湿度影响不敏感,无其他可能的干扰。 该设备非常适合OSHA规定要求的个人监控程序,所获得的分析数据代表时间加权平均曝光,无需进一步的数据评估。