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1. 发明授权

US5505687A Device for measuring incident light in a body cavity 失效
标题翻译：用于测量体腔内的入射光的装置
公开(公告)号：US5505687A
公开(公告)日：1996-04-09
申请号：US395005
申请日：1995-02-27
申请人： McClellan M. Walther , Thomas F. DeLaney , Frank Harrington , Paul D. Smith , Walter S. Friauf
发明人： McClellan M. Walther , Thomas F. DeLaney , Frank Harrington , Paul D. Smith , Walter S. Friauf
IPC分类号： A61B18/24 , A61N5/06 , A61B1/00 , A61B1/06 , A61B5/05
CPC分类号： A61B18/24 , A61N5/0601
摘要： An obturator for measuring incident light in a remote situs such as a body cavity which includes a treatment tubular member through which light is delivered to the remote situs and one or more auxiliary tubular members through which incident light in the remote situs is transmitted to an external light detector. The treatment and auxiliary tubular members are attached to a connector element which is in turn connected to a cystoscope lens port. The treatment and auxiliary tubular members are aligned off-center with respect to the central axis of the obturator so that a cystoscope lens can be inserted in the lens port and pass through the axial center of the obturator. Each auxiliary tubular member receives incident light from a different portion of the remote situs. The apparatus is particularly useful for conducting phototherapy in body cavities and has been demonstrated in the phototherapy treatment of superficial cancer in the bladder.
摘要翻译：用于测量诸如体腔的远程位置中的入射光的闭孔器，其包括处理管状构件，光通过该管状构件传送到远程位置，以及一个或多个辅助管状构件，通过该一个或多个辅助管状构件将远程位置的入射光透射到外部光检测器治疗和辅助管状构件附接到连接器元件，该连接器元件又连接到膀胱镜透镜端口。处理和辅助管状构件相对于闭孔器的中心轴线偏离中心，使得可以将透镜端口中的透镜镜头插入并穿过闭塞器的轴向中心。每个辅助管状构件接收来自远程位置的不同部分的入射光。该装置对于在体腔中进行光疗特别有用，并已在膀胱中浅层癌症的光疗治疗中得到证实。

2. 发明授权

US5575751A Device for measuring incident light in a body cavity 失效
标题翻译：用于测量体腔内的入射光的装置
公开(公告)号：US5575751A
公开(公告)日：1996-11-19
申请号：US294892
申请日：1994-08-22
申请人： McClellan M. Walther , Thomas F. DeLaney , Frank Harrington , Paul D. Smith , Walter S. Friauf
发明人： McClellan M. Walther , Thomas F. DeLaney , Frank Harrington , Paul D. Smith , Walter S. Friauf
IPC分类号： A61B18/24 , A61N5/06 , A61B1/00 , A61B1/06 , A61B5/05
CPC分类号： A61B18/24 , A61N5/0601
摘要： A device for measuring incident light in a remote situs such as a body cavity which includes a central tubular member through which light is delivered to the remote situs and one or more auxiliary tubular members through which incident light in the remote situs is transmitted to a light detector. Each auxiliary tubular member receives incident light from a different portion of the remote situs. The apparatus is particularly useful for conducting phototherapy in body cavities and has been demonstrated in the phototherapy treatment of superficial cancer in a bladder.
摘要翻译：用于测量诸如体腔的远程位置中的入射光的装置，其包括中心管状构件，光通过该中心管状构件传送到远程位置，以及一个或多个辅助管状构件，远程位置中的入射光通过该辅助管状构件传递到光探测器。每个辅助管状构件接收来自远程位置的不同部分的入射光。该装置对于在体腔中进行光疗特别有用，并且已在膀胱中浅层癌症的光疗治疗中得到证实。

3. 发明授权

US5730700A Method for measuring incident light in a body cavity 失效
标题翻译：测量体腔入射光的方法
公开(公告)号：US5730700A
公开(公告)日：1998-03-24
申请号：US592440
申请日：1996-01-26
申请人： McClellan M. Walther , Thomas F. DeLaney , Frank Harrington , Paul D. Smith , Walter S. Friauf
发明人： McClellan M. Walther , Thomas F. DeLaney , Frank Harrington , Paul D. Smith , Walter S. Friauf
IPC分类号： A61B18/24 , A61N5/06 , A61B1/07
CPC分类号： A61B18/24 , A61N5/0601
摘要： An obturator for measuring incident light in a remote situs such as a body cavity which includes a treatment tubular member through which light is delivered to the remote situs and one or more auxiliary tubular members through which incident light in the remote situs is transmitted to an external light detector. The treatment and auxiliary tubular members are attached to a connector element which is in turn connected to a cystoscope lens port. The treatment and auxiliary tubular members are aligned off-center with respect to the central axis of the obturator so that a cystoscope lens can be inserted in the lens port and pass through the axial center of the obturator. Each auxiliary tubular member receives incident light from a different portion of the remote situs. The apparatus is particularly useful for conducting phototherapy in body cavities and has been demonstrated in the phototherapy treatment of superficial cancer in the bladder.
摘要翻译：用于测量诸如体腔的远程位置中的入射光的闭孔器，其包括处理管状构件，光通过该管状构件传送到远程位置，以及一个或多个辅助管状构件，通过该一个或多个辅助管状构件将远程位置的入射光透射到外部光检测器治疗和辅助管状构件附接到连接器元件，该连接器元件又连接到膀胱镜透镜端口。处理和辅助管状构件相对于闭孔器的中心轴线偏离中心，使得可以将透镜端口中的透镜镜头插入并穿过闭塞器的轴向中心。每个辅助管状构件接收来自远程位置的不同部分的入射光。该装置对于在体腔中进行光疗特别有用，并已在膀胱中浅层癌症的光疗治疗中得到证实。

4. 发明授权

US5435307A Surface fluorescent monitor 失效
标题翻译：表面荧光显示器
公开(公告)号：US5435307A
公开(公告)日：1995-07-25
申请号：US676581
申请日：1991-03-29
申请人： Walter S. Friauf , Paul D. Smith , John W. Cole , Joseph F. Fessler , Roger E. Solomon , Eric F. Bernstein
发明人： Walter S. Friauf , Paul D. Smith , John W. Cole , Joseph F. Fessler , Roger E. Solomon , Eric F. Bernstein
IPC分类号： A61B5/00
CPC分类号： A61B5/0059
摘要： A method of optimizing photodynamic therapy in which retained concentrations of photosensitizers administered are measured on a real time basis by percutaneous measurements of fluorescence. A light weight hand held fluorometer is used to percutaneously measure fluorescence emitted by photosensitizers in a tissue situs that is subject to photodynamic therapy. The use of real time determinations of the concentration of photosensitizers allow optimization of illumination intensity and duration.
摘要翻译：优化光动力疗法的方法，其中通过经皮测量荧光实时测量所施用的光敏剂的保留浓度。使用轻量级的手持式荧光计经皮测量经受光动力学治疗的组织部位中的光敏剂发出的荧光。使用光敏剂浓度的实时测定可以优化照明强度和持续时间。

5. 发明授权

US5502386A Pulsed low frequency EPR spectrometer and imager 失效
公开(公告)号：US5502386A
公开(公告)日：1996-03-26
申请号：US340100
申请日：1994-11-15
申请人： John Bourg , James Mitchell , Mark Mirotznik , Bradley Roth , Sankaran Subramanian , Murali Cherukuri , Paul G. Zablocky , Thomas J. Pohida , Paul D. Smith , Walter S. Friauf , Rolf G. Tschudin
发明人： John Bourg , James Mitchell , Mark Mirotznik , Bradley Roth , Sankaran Subramanian , Murali Cherukuri , Paul G. Zablocky , Thomas J. Pohida , Paul D. Smith , Walter S. Friauf , Rolf G. Tschudin
IPC分类号： G01R33/20 , A61B5/055 , G01N24/10 , G01R33/60
CPC分类号： G01R33/60
摘要： An EPR imager and spectrometer includes pulse generating system for generating broadband pulses having an RF carrier frequency that is not highly absorbed by biological samples. The pulse generating system includes up and down chirp convertors for frequency modulating a carrier frequency pulse and compressing the frequency modulated pulse to form a broadband excitation pulse of high energy. Such a machine could form the basis of a clinical imaging device capable of high sensitivity to free radical species in human patients.

6. 发明授权

US5519534A Irradiance attachment for an optical fiber to provide a uniform level of illumination across a plane 失效
标题翻译：用于光纤的辐射附件，以提供跨平面的均匀的照明水平
公开(公告)号：US5519534A
公开(公告)日：1996-05-21
申请号：US248918
申请日：1994-05-25
申请人： Paul D. Smith , John Cole , Frank Harrington , Eric F. Bernstein
发明人： Paul D. Smith , John Cole , Frank Harrington , Eric F. Bernstein
IPC分类号： A61B18/22 , A61N5/06 , G02B5/02 , A61B17/36 , A61N5/00 , G01J1/04
CPC分类号： A61N5/062 , G02B5/02 , A61B2018/2261 , A61N2005/0644 , A61N2005/0666 , Y10S359/90
摘要： A irradiation attachment for an optical fiber which provides an output of light that has a highly uniform intensity. The device includes a hollow spherical shell having a diffusive reflective surface or target supported therein. Light is directed into the hollow spherical shell so that it reflects off the diffusive reflective surface or target. The reflected light is internally reflected off the inner surface of the hollow spherical shell several times before passing through an output aperture. As a result of the internal reflection within the hollow spherical shell, the light leaving the device has a highly uniform intensity. The device is particularly useful for photodynamic therapy.
摘要翻译：用于光纤的照射附件，其提供具有高度均匀强度的光的输出。该装置包括具有支撑在其中的漫射反射表面或靶的中空球壳。光被引导到中空球壳中，使得其反射离开漫射反射表面或靶。在通过输出孔之前，反射光在中空球壳的内表面内部被反射几次。由于在空心球壳内的内部反射，离开设备的光具有高度均匀的强度。该装置对光动力疗法特别有用。

7. 发明申请

US20110138881A1 SENSOR APPARATUS AND METHOD THEREFOR 有权
标题翻译：传感器装置及其方法
公开(公告)号：US20110138881A1
公开(公告)日：2011-06-16
申请号：US12692205
申请日：2010-01-22
申请人： Beth A. Jones , Paul Rennie , Robert Pallant , Paul D. Smith
发明人： Beth A. Jones , Paul Rennie , Robert Pallant , Paul D. Smith
IPC分类号： G01N27/12 , G01N7/00
CPC分类号： G01N27/12
摘要： A sensor apparatus includes a metal oxide semiconductor sensor and a housing having an internal chamber in which the sensor is disposed. The housing includes at least one window for the ingress of a gas into the internal chamber from an atmosphere exterior to the housing. A gas-selective barrier is disposed across the at least one window.
摘要翻译：传感器装置包括金属氧化物半导体传感器和具有设置有传感器的内部室的壳体。壳体包括至少一个用于从外壳外部的气体将气体进入内部室的窗口。气体选择性屏障穿过所述至少一个窗口设置。

8. 发明申请

US20090109587A1 OVER VOLTAGE PROTECTION FOR REDUCED LEVEL ELECTRICAL SIGNAL INTERFACES 有权
标题翻译：过电压保护降低电平信号接口
公开(公告)号：US20090109587A1
公开(公告)日：2009-04-30
申请号：US11925218
申请日：2007-10-26
申请人： Paul D. Smith , Matthew Lee Boggs , Charles Komsri
发明人： Paul D. Smith , Matthew Lee Boggs , Charles Komsri
IPC分类号： H02H3/22 , H02H3/20
CPC分类号： H02H3/202 , H02H9/04
摘要： A device for protecting sensitive electronic equipment from low level signal lines short circuited to high voltage power sources includes a switch that open the circuit between the data lines and the sensitive computing equipment if a high voltage condition is detected on the data lines. Otherwise, the switch remains closed and data can be transmitted to the computing equipment.
摘要翻译：用于将敏感电子设备保护到与高电压电源短路的低电平信号线路的装置包括如果在数据线上检测到高电压状况则打开数据线与敏感计算设备之间的电路的开关。否则，交换机保持关闭，并且可以将数据传输到计算设备。

9. 发明授权

US06420579B1 Organometallic fluorenyl compounds, preparation, and use 失效
标题翻译：有机金属芴基化合物，制备和使用
公开(公告)号：US06420579B1
公开(公告)日：2002-07-16
申请号：US08352936
申请日：1994-12-09
申请人： Helmut G. Alt , Syriac J. Palackal , Konstantinos Patsidis , M. Bruce Welch , Rolf L. Geerts , Eric T. Hsieh , Max P. McDaniel , Gil R. Hawley , Paul D. Smith
发明人： Helmut G. Alt , Syriac J. Palackal , Konstantinos Patsidis , M. Bruce Welch , Rolf L. Geerts , Eric T. Hsieh , Max P. McDaniel , Gil R. Hawley , Paul D. Smith
IPC分类号： C07F1700
CPC分类号： B01J31/143 , B01J31/2295 , B01J2531/40 , B01J2531/46 , B01J2531/48 , B01J2531/49 , B01J2531/50 , B01J2531/56 , C07C13/567 , C07C22/04 , C07C49/747 , C07C51/31 , C07C51/373 , C07C51/377 , C07C63/331 , C07C63/49 , C07C65/36 , C07C2601/10 , C07C2603/18 , C07F7/0805 , C07F7/081 , C07F17/00 , C08F4/63912 , C08F4/63922 , C08F4/65912 , C08F4/65927 , C08F10/00 , C08F110/02 , C08F110/06 , C08F210/16 , Y10S526/943 , C07C65/38 , C08F2500/12 , C08F2500/17 , C08F2500/20 , C08F2500/01 , C08F2500/08 , C08F210/14
摘要： Bridged and unbridged fluorenyl-containing metallocenes of the formula R″x(FlRn)(CpRm)MQk wherein Fl is a fluorenyl radical, Cp is a cyclopentadienyl, indenyl, tetrahydroindenyl, or fluorenyl radical, each R is an organo radical, R″ is a structural bridge linking (FlRn) and (CpRm), M is a metal selected from the group consisting of IVB, VB, and VIB metals, each Q is selected from the group consisting of hydrocarbyl or hydrocarbyloxy radicals and halogen, x is 1 or 0, k is an integer sufficient to fill out the remaining valences of M, n is in the range of 0 to 7, and m is 0 to 7, further characterized by the fact that if (CpRm) is unsubstituted fluorenyl and metallocene is an unbridged metallocene, then n is 1 to 7 and if R″ is 1,1-dimethylmethylene and (CpRm) is unsubstituted cyclopentadienyl or 3-methylcyclopentadienyl, then n is 1 to 7.
摘要翻译：桥接和未桥连的含芴基的茂金属的式R''x（FlRn）（CpRm）MQk其中F1是芴基，Cp是环戊二烯基，茚基，四氢茚基或芴基，每个R是有机基团，R' 是连接（FlRn）和（CpRm）的结构桥，M是选自IVB，VB和VIB金属的金属，每个Q选自烃基或烃氧基和卤素，x是 1或0，k是足以填充M的剩余价数的整数，n在0至7的范围内，m为0至7，其特征还在于如果（CpRm）为未取代的芴基和茂金属是未桥连金属茂，n为1〜7，如果R“为1,1-二甲基亚甲基，（CpRm）为未取代的环戊二烯基或3-甲基环戊二烯基，n为1〜7。

10. 发明授权

US6162936A Organometallic fluorenyl compounds, preparation, and use 失效
标题翻译：有机金属芴基化合物，制备和使用
公开(公告)号：US6162936A
公开(公告)日：2000-12-19
申请号：US85945
申请日：1998-05-28
申请人： Helmut G. Alt , Syriac J. Palackal , Konstantinos Patsidis , M. Bruce Welch , Rolf L. Geerts , Eric T. Hsieh , Max P. McDaniel , Gil R. Hawley , Paul D. Smith
发明人： Helmut G. Alt , Syriac J. Palackal , Konstantinos Patsidis , M. Bruce Welch , Rolf L. Geerts , Eric T. Hsieh , Max P. McDaniel , Gil R. Hawley , Paul D. Smith
IPC分类号： B01J31/22 , C07C13/567 , C07C22/04 , C07C49/747 , C07C51/31 , C07C51/373 , C07C51/377 , C07C63/331 , C07C63/49 , C07C65/36 , C07F7/08 , C07F17/00 , C08F4/639 , C08F4/6392 , C08F4/64 , C08F4/642 , C08F4/659 , C08F4/6592 , C08F10/00 , C08F110/02 , C08F110/06 , C08F210/16 , C07F9/00 , C07F7/00 , C07F7/28
CPC分类号： B01J31/143 , B01J31/2295 , B01J2531/40 , B01J2531/46 , B01J2531/48 , B01J2531/49 , B01J2531/50 , B01J2531/56 , C07C13/567 , C07C22/04 , C07C49/747 , C07C51/31 , C07C51/373 , C07C51/377 , C07C63/331 , C07C63/49 , C07C65/36 , C07C2601/10 , C07C2603/18 , C07F7/0805 , C07F7/081 , C07F17/00 , C08F4/63912 , C08F4/63922 , C08F4/65912 , C08F4/65927 , C08F10/00 , C08F110/02 , C08F110/06 , C08F210/16 , Y10S526/943 , C07C65/38 , C08F2500/12 , C08F2500/17 , C08F2500/20 , C08F2500/01 , C08F2500/08 , C08F210/14
摘要： Fluorenyl-containing metallocenes are disclosed along with methods for making the metallocenes. Also disclosed are methods for using the metallocenes as polymerization catalysts. In addition, polymers resulting from such polymerizations are disclosed.
摘要翻译：公开了含芴基金属茂以及制备金属茂的方法。还公开了使用金属茂作为聚合催化剂的方法。此外，公开了由这种聚合产生的聚合物。

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