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1. 发明申请

US20130292004A1 DEVICES AND METHODS FOR AUTOMATICALLY RECONSTITUTING A DRUG 审中-公开
标题翻译：用于自动重新配制药物的装置和方法
公开(公告)号：US20130292004A1
公开(公告)日：2013-11-07
申请号：US13813730
申请日：2010-08-10
申请人： Maurice Ducret , Jean-Noel Fehr , Walter Fuerst , Sofia Galbraith , Joerg Luemkemann , Marcel Mueller , Urs Rindlisbacher , Simon Scheurer , Oliver Shergold
发明人： Maurice Ducret , Jean-Noel Fehr , Walter Fuerst , Sofia Galbraith , Joerg Luemkemann , Marcel Mueller , Urs Rindlisbacher , Simon Scheurer , Oliver Shergold
IPC分类号： A61J1/20
CPC分类号： A61J1/20 , A61J1/062 , A61J1/201 , A61J1/2089 , B01F3/12 , B01F11/0002 , B01F15/0203 , B01F15/0205 , B01F15/0212 , B01F15/0225 , B01F15/0237 , B01F15/0266 , B01F15/0278 , B01F15/0291 , B01F2215/0034 , B01F2215/0454
摘要： Devices and methods are disclosed which automatically reconstitute a drug, such as e.g., a lyophilized drug. A vial (30) containing the drug is fluidly coupled to a cartridge (12) containing a reconstitution liquid with a fluid conduit (14f), wherein an entry point is defined where the fluid conduit enters the vial (30). The device (10) automatically adjusts orientation of the vial (30) such that the entry point of the vial is gravitationally higher than the drug in the vial (30), and automatically transfers the reconstitution liquid out of the cartridge (12) and into the vial (30) to create a reconstituted drug. The device (10) also automatically adjusts the orientation of the vial (30) such that the entry point of the vial is gravitationally lower than the reconstituted drug, and automatically transfers the reconstituted drug from the vial (30) and into the cartridge (12).
摘要翻译：公开了自动重建药物的装置和方法，例如冻干药物。含有药物的小瓶（30）流体地联接到包含具有流体导管（14f）的重构液体的药筒（12），其中限定流体导管进入小瓶（30）的入口点。装置（10）自动调节小瓶（30）的取向，使得小瓶的入口点重力地高于小瓶（30）中的药物，并且自动地将重构液体转移出盒（12）并进入小瓶（30）以产生重构药物。装置（10）还自动调节小瓶（30）的取向，使得小瓶的入口点重力地比重构的药物低，并且自动地将重组的药物从小瓶（30）转移到筒（12）中）。

2. 发明申请

US20130035658A1 Apparatuses, Systems, And Methods For Filling A Container With A Liquid Drug 有权
标题翻译：用液体药物填充容器的装置，系统和方法
公开(公告)号：US20130035658A1
公开(公告)日：2013-02-07
申请号：US13492008
申请日：2012-06-08
申请人： Roger Haenggi , Urs Rindlisbacher , Franco Moia , Marcel Mueller , Christoph Huwiler , Florian Kuhni , Joerg Wermelinger , Andreas Lischewski , Christian Classen , Tilo Callenbach , Louis Widmer , Maurice Ducret
发明人： Roger Haenggi , Urs Rindlisbacher , Franco Moia , Marcel Mueller , Christoph Huwiler , Florian Kuhni , Joerg Wermelinger , Andreas Lischewski , Christian Classen , Tilo Callenbach , Louis Widmer , Maurice Ducret
IPC分类号： A61J1/20 , A61J1/10
CPC分类号： A61J1/2096 , A61J1/20 , A61J1/201 , A61J1/2048 , A61M5/24 , B65B3/003
摘要： In one embodiment, a method of filling a container with a liquid drug from a drug reservoir may include: a) connecting a container and a drug reservoir with a cannula such that the drug reservoir and the container fluidically communicate with each other via the cannula, while being hermetically sealed; b) reducing a first volume contained within the container to displace a gaseous medium from the first volume of the container via the cannula into a second volume contained within the drug reservoir; c) increasing the first volume of the container to displace the liquid drug from the second volume of the drug reservoir into the first volume of the container to fill the container; and d) disconnecting the container and the drug reservoir. Before performing action d), action b) and action c) can be successively performed more than once to stepwise increase an amount of liquid drug displaced.
摘要翻译：在一个实施例中，从药物储存器填充液体药物的容器的方法可以包括：a）将容器和药物储存器与套管连接，使得药物储存器和容器经由套管彼此流体连通，同时密封; b）减少容纳在容器内的第一容积，以将气态介质从容器的第一容积经由套管置换成容纳在药物贮存器内的第二容积; c）增加容器的第一容积以将液体药物从药物储存器的第二体积移位到容器的第一容积中以填充容器; 和d）断开容器和药物储存器。在执行动作d）之前，动作b）和动作c）可以连续执行多次以逐步增加液体药物的移动量。

3. 发明授权

US09089647B2 Apparatuses, systems, and methods for filling a container with a liquid drug 有权
标题翻译：用液体药物填充容器的装置，系统和方法
公开(公告)号：US09089647B2
公开(公告)日：2015-07-28
申请号：US13492008
申请日：2012-06-08
申请人： Roger Haenggi , Urs Rindlisbacher , Franco Moia , Marcel Mueller , Christoph Huwiler , Florian Kuhni , Joerg Wermelinger , Andreas Lischewski , Christian Classen , Tilo Callenbach , Louis Widmer , Maurice Ducret
发明人： Roger Haenggi , Urs Rindlisbacher , Franco Moia , Marcel Mueller , Christoph Huwiler , Florian Kuhni , Joerg Wermelinger , Andreas Lischewski , Christian Classen , Tilo Callenbach , Louis Widmer , Maurice Ducret
IPC分类号： A61B19/00 , A61M5/24
CPC分类号： A61J1/2096 , A61J1/20 , A61J1/201 , A61J1/2048 , A61M5/24 , B65B3/003
摘要： In one embodiment, a method of filling a container with a liquid drug from a drug reservoir may include: a) connecting a container and a drug reservoir with a cannula such that the drug reservoir and the container fluidically communicate with each other via the cannula, while being hermetically sealed; b) reducing a first volume contained within the container to displace a gaseous medium from the first volume of the container via the cannula into a second volume contained within the drug reservoir; c) increasing the first volume of the container to displace the liquid drug from the second volume of the drug reservoir into the first volume of the container to fill the container; and d) disconnecting the container and the drug reservoir. Before performing action d), action b) and action c) can be successively performed more than once to stepwise increase an amount of liquid drug displaced.
摘要翻译：在一个实施例中，从药物储存器填充液体药物的容器的方法可以包括：a）将容器和药物储存器与套管连接，使得药物储存器和容器经由套管彼此流体连通，同时密封; b）减少容纳在容器内的第一容积，以将气态介质从容器的第一容积经由套管置换成容纳在药物贮存器内的第二容积; c）增加容器的第一容积以将液体药物从药物储存器的第二体积移位到容器的第一容积中以填充容器; 和d）断开容器和药物储存器。在执行动作d）之前，动作b）和动作c）可以连续执行多次以逐步增加液体药物的移动量。

4. 发明申请

US20140034185A1 Connector Device 有权
标题翻译：连接器装置
公开(公告)号：US20140034185A1
公开(公告)日：2014-02-06
申请号：US14049329
申请日：2013-10-09
申请人： Marcel Mueller , Maurice Ducret
发明人： Marcel Mueller , Maurice Ducret
IPC分类号： A61J1/20
CPC分类号： A61J1/2065 , A61J1/1406 , A61J1/2013 , A61J1/2051 , A61J1/2055 , A61J1/2089 , A61M39/14 , A61M2039/0027
摘要： A connector device for connecting two containers with first and second members slidably displaceable in regard to each other along an axis between a first and a second position is presented. The first member comprises a needle parallel to the axis so that the first container's septum is penetrated by one end of the needle when the first container is introduced into the first member. The second member comprises a coupling to the second container. The other needle end penetrates the second container's septum when the members are in the second position establishing a connection between the two containers. The first member comprises a coupling to the second container coupled to the second member. The first member can couple to the second container when the two members are in the second position and cannot couple to the second container when the two members are in the first position.
摘要翻译：一种用于连接两个容器的连接器装置，其中第一和第二构件相对于第一和第二位置之间的轴线相对于彼此可滑动地移位。第一构件包括平行于轴线的针，使得当第一容器被引入第一构件时，第一容器的隔膜穿过针的一端。第二构件包括与第二容器的联接。当构件处于建立两个容器之间的连接的第二位置时，另一针头穿透第二容器的隔膜。第一构件包括联接到联接到第二构件的第二容器的联接件。当两个构件处于第二位置时，第一构件可以联接到第二容器，并且当两个构件处于第一位置时不能联接到第二容器。

5. 发明申请

US20140081206A1 Medical Assembly Comprising Monitoring Device 审中-公开
标题翻译：包括监测装置的医疗组件
公开(公告)号：US20140081206A1
公开(公告)日：2014-03-20
申请号：US13906492
申请日：2013-05-31
申请人： Marcel Mueller , Edgar Jeanbourquin , Florian Zoergiebel , Franco Moia
发明人： Marcel Mueller , Edgar Jeanbourquin , Florian Zoergiebel , Franco Moia
IPC分类号： A61M5/50 , A61M5/168
CPC分类号： A61M5/5086 , A61M5/158 , A61M5/168 , A61M2005/14268 , A61M2005/1585 , A61M2005/1587 , A61M2205/583 , Y10T29/49826
摘要： A method of preparing at least part of a medical device for application and a medical assembly for preparing or storing the at least one disposable unit of the medical device is presented. The medical assembly comprises a chemical or physical monitoring device for counting and/or displaying a time period of application and/or time remaining before required disposal or replacement of the disposable unit. The monitoring device is automatically activated by moving the at least one disposable unit relative to a second unit of the medical assembly for preparing or positioning the disposable unit for use with the medical device; assembling the at least one disposable unit and the medical device; and/or withdrawing the disposable unit of a storage compartment of the second unit.
摘要翻译：提出了制备用于应用的医疗装置的至少一部分的方法和用于准备或存储医疗装置的至少一个一次性单元的医疗组件。医疗组件包括用于在所需处置或更换一次性单元之前计数和/或显示施用时间和/或剩余时间的化学或物理监测装置。通过相对于医疗组件的第二单元移动至少一个一次性单元来自动启动监视装置，用于准备或定位与医疗装置一起使用的一次性单元; 组装所述至少一个一次性单元和所述医疗装置; 和/或撤回第二单元的储存室的一次性单元。

6. 发明授权

US09241739B2 Spinal stabilizing and guiding fixation system 有权
标题翻译：脊柱稳定和导向固定系统
公开(公告)号：US09241739B2
公开(公告)日：2016-01-26
申请号：US13063323
申请日：2009-09-11
申请人： Marcel Mueller , Meret Labhart
发明人： Marcel Mueller , Meret Labhart
IPC分类号： A61B17/70
CPC分类号： A61B17/705 , A61B17/704 , A61B17/7041 , A61B17/7046 , A61B17/7053 , A61B17/7056 , A61B17/846 , A61B17/86 , A61B2017/00862
摘要： A system to stabilize and guide the growth of the spinal column includes an elongated support member having a width and a length and a guiding connector having a bone connecting portion and a guiding portion. The bone connecting portion secures the guiding connector to a vertebrae and the guiding portion has a bearing element with a passageway adapted to receive the elongated support member. The bearing element permits relative sliding movement of the elongated support element in the passageway of the bearing element. The system may further include a bone fixation element has an elongated support member receiving channel, a locking mechanism and a bone anchoring portion. The bone anchoring portion secures the bone fixation element to bone. The locking mechanism secures the elongated support member in the channel. The guiding connector is moveable along the elongated support member to permit and control the growth of the spinal column along a predetermined path.
摘要翻译：用于稳定和引导脊柱生长的系统包括具有宽度和长度的细长支撑构件和具有骨连接部分和引导部分的引导连接器。骨连接部分将引导连接器固定到椎骨上，并且引导部分具有带有适于容纳细长支撑构件的通道的支承元件。轴承元件允许细长支撑元件在轴承元件的通道中的相对滑动运动。该系统还可以包括骨固定元件，其具有细长的支撑构件接收通道，锁定机构和骨锚固部分。骨固定部分将骨固定元件固定在骨上。锁定机构将细长的支撑构件固定在通道中。引导连接器可沿着细长支撑构件移动，以允许并控制脊柱沿预定路径的生长。

7. 发明申请

US20110270314A1 SPINAL STABILIZING AND GUIDING FIXATION SYSTEM 有权
标题翻译：脊柱稳定和引导固定系统
公开(公告)号：US20110270314A1
公开(公告)日：2011-11-03
申请号：US13063323
申请日：2009-09-11
申请人： Marcel Mueller , Meret Labhart
发明人： Marcel Mueller , Meret Labhart
IPC分类号： A61B17/70 , A61B17/56
CPC分类号： A61B17/705 , A61B17/704 , A61B17/7041 , A61B17/7046 , A61B17/7053 , A61B17/7056 , A61B17/846 , A61B17/86 , A61B2017/00862
摘要： A system to stabilize and guide the growth of the spinal column includes an elongated support member having a width and a length and a guiding connector having a bone connecting portion and a guiding portion. The bone connecting portion secures the guiding connector to a vertebrae and the guiding portion has a bearing element with a passageway adapted to receive the elongated support member. The bearing element permits relative sliding movement of the elongated support element in the passageway of the bearing element. The system may further include a bone fixation element has an elongated support member receiving channel, a locking mechanism and a bone anchoring portion. The bone anchoring portion secures the bone fixation element to bone. The locking mechanism secures the elongated support member in the channel. The guiding connector is moveable along the elongated support member to permit and control the growth of the spinal column along a predetermined path.
摘要翻译：用于稳定和引导脊柱生长的系统包括具有宽度和长度的细长支撑构件和具有骨连接部分和引导部分的引导连接器。骨连接部分将引导连接器固定到椎骨上，并且引导部分具有带有适于容纳细长支撑构件的通道的支承元件。轴承元件允许细长支撑元件在轴承元件的通道中的相对滑动运动。该系统还可以包括骨固定元件，其具有细长的支撑构件接收通道，锁定机构和骨锚固部分。骨固定部分将骨固定元件固定在骨上。锁定机构将细长的支撑构件固定在通道中。引导连接器可沿着细长支撑构件移动，以允许并控制脊柱沿预定路径的生长。

8. 发明授权

US5670185A Die assembly for extruding edible substances 失效
标题翻译：用于挤出食用物质的模具组件
公开(公告)号：US5670185A
公开(公告)日：1997-09-23
申请号：US540939
申请日：1995-10-11
申请人： Ernst Heck , Marcel Mueller , Adrian Weber
发明人： Ernst Heck , Marcel Mueller , Adrian Weber
IPC分类号： A21C3/04 , A21C20060101 , A21C3/08 , A21C11/00 , A21C11/16 , A23P1/12 , B29C20060101 , B29C47/06 , B29C47/18 , B29C47/24 , B29C47/28
CPC分类号： B29C47/24 , A21C11/163 , A21C3/04 , A21C3/08 , B29C47/0016 , B29C47/003
摘要： An extrusion die assembly has a body member which rotatably houses a barrel member which provides a tubular passage. The body member has an inlet channel for passage of a plasticized, especially edible, substance to the barrel member tubular passage which extends from a junction with the body member to at least one outlet channel. A rotary seal is provided at a junction between the body member and barrel member.
摘要翻译：挤出模具组件具有可旋转地容纳提供管状通道的筒构件的主体构件。主体构件具有入口通道，用于将塑化的特别是可食用的物质通向从与主体构件的接合部延伸到至少一个出口通道的筒构件管状通道。旋转密封件设置在主体部件和筒部件之间的连接处。

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