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1. 发明申请

US20060200119A1 Methods and devices for ablation 有权
公开(公告)号：US20060200119A1
公开(公告)日：2006-09-07
申请号：US11401345
申请日：2006-04-11
申请人： Matthias Vaska , John Crowe , Gary Miller , Jonathan Podmore , Gerard Champsaur , Drew Hoffmann , Casey Tansey
发明人： Matthias Vaska , John Crowe , Gary Miller , Jonathan Podmore , Gerard Champsaur , Drew Hoffmann , Casey Tansey
IPC分类号： A61B18/18
CPC分类号： A61B17/22012 , A61B5/0422 , A61B17/2202 , A61B17/2251 , A61B18/00 , A61B18/02 , A61B18/1402 , A61B18/148 , A61B18/1482 , A61B18/1492 , A61B34/20 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/003 , A61B2017/22077 , A61B2017/2253 , A61B2017/3419 , A61B2018/00023 , A61B2018/0016 , A61B2018/00232 , A61B2018/00261 , A61B2018/00285 , A61B2018/00291 , A61B2018/00351 , A61B2018/00363 , A61B2018/00375 , A61B2018/00392 , A61B2018/00577 , A61B2018/00654 , A61B2018/00797 , A61B2018/00839 , A61B2018/142 , A61B2018/1467 , A61B2018/1472 , A61B2090/3614 , A61B2090/3782 , A61B2090/395 , A61B2218/002 , A61B2218/007 , A61M25/0041 , A61M25/0084 , A61M25/04 , A61M25/1002 , A61M25/1011 , A61M2025/0293 , A61M2025/1072 , A61N1/06 , A61N1/362 , A61N7/02
摘要： An ablating device has a cover which holds an interface material such as a gel. The cover contains the interface material during initial placement of the device. The ablating device may also have a removable tip or a membrane filled with fluid. In still another aspect, the ablating device may be submerged in liquid during operation.

2. 发明申请

US20080045936A1 Methods and devices for ablation 有权
标题翻译：消融的方法和装置
公开(公告)号：US20080045936A1
公开(公告)日：2008-02-21
申请号：US11785427
申请日：2007-04-17
申请人： Matthias Vaska , Stephen Boyd , Hanson Gifford , James Cox , Jonathan Podmore , John Crowe , Michael Holzbaur , Timothy Ciciarelli , Drew Hoffmann , Casey Tansey , John Sliwa , Scott Anderson
发明人： Matthias Vaska , Stephen Boyd , Hanson Gifford , James Cox , Jonathan Podmore , John Crowe , Michael Holzbaur , Timothy Ciciarelli , Drew Hoffmann , Casey Tansey , John Sliwa , Scott Anderson
IPC分类号： A61B18/18
CPC分类号： A61B17/22012 , A61B5/0422 , A61B17/2202 , A61B17/2251 , A61B18/00 , A61B18/02 , A61B18/1402 , A61B18/148 , A61B18/1482 , A61B18/1492 , A61B34/20 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/003 , A61B2017/22077 , A61B2017/2253 , A61B2017/3419 , A61B2018/00023 , A61B2018/0016 , A61B2018/00232 , A61B2018/00261 , A61B2018/00285 , A61B2018/00291 , A61B2018/00351 , A61B2018/00363 , A61B2018/00375 , A61B2018/00392 , A61B2018/00577 , A61B2018/00654 , A61B2018/00797 , A61B2018/00839 , A61B2018/142 , A61B2018/1467 , A61B2018/1472 , A61B2090/3614 , A61B2090/3782 , A61B2090/395 , A61B2218/002 , A61B2218/007 , A61M25/0041 , A61M25/0084 , A61M25/04 , A61M25/1002 , A61M25/1011 , A61M2025/0293 , A61M2025/1072 , A61N1/06 , A61N1/362 , A61N7/02
摘要： An ablating device has a cover which holds an interface material such as a gel. The cover contains the interface material during initial placement of the device. The ablating device may also have a removable tip or a membrane filled with fluid. In still another aspect, the ablating device may be submerged in liquid during operation.
摘要翻译：消融装置具有保持诸如凝胶的界面材料的盖。在设备的初始放置期间，盖子包含界面材料。烧蚀装置还可以具有可移除的尖端或填充有流体的膜。在另一方面，在操作期间，烧蚀装置可以浸没在液体中。

3. 发明授权

US09055959B2 Methods and devices for ablation 有权
公开(公告)号：US09055959B2
公开(公告)日：2015-06-16
申请号：US11785427
申请日：2007-04-17
申请人： Matthias Vaska , Stephen W. Boyd , Hanson S. Gifford , James L. Cox , Jonathan L. Podmore , John E. Crowe , Michael C Holzbaur , Timothy E. Ciciarelli , Drew Hoffmann , Casey Tansey , John W. Sliwa , Scott C. Anderson
发明人： Matthias Vaska , Stephen W. Boyd , Hanson S. Gifford , James L. Cox , Jonathan L. Podmore , John E. Crowe , Michael C Holzbaur , Timothy E. Ciciarelli , Drew Hoffmann , Casey Tansey , John W. Sliwa , Scott C. Anderson
IPC分类号： A61B18/14 , A61B17/22 , A61B17/225 , A61B18/00 , A61B18/02 , A61N1/06 , A61N7/02 , A61B5/042 , A61B19/00 , A61B17/00 , A61B17/34 , A61M25/00 , A61M25/04 , A61M25/10 , A61M25/02 , A61N1/362
CPC分类号： A61B17/22012 , A61B5/0422 , A61B17/2202 , A61B17/2251 , A61B18/00 , A61B18/02 , A61B18/1402 , A61B18/148 , A61B18/1482 , A61B18/1492 , A61B34/20 , A61B2017/00243 , A61B2017/00247 , A61B2017/00252 , A61B2017/003 , A61B2017/22077 , A61B2017/2253 , A61B2017/3419 , A61B2018/00023 , A61B2018/0016 , A61B2018/00232 , A61B2018/00261 , A61B2018/00285 , A61B2018/00291 , A61B2018/00351 , A61B2018/00363 , A61B2018/00375 , A61B2018/00392 , A61B2018/00577 , A61B2018/00654 , A61B2018/00797 , A61B2018/00839 , A61B2018/142 , A61B2018/1467 , A61B2018/1472 , A61B2090/3614 , A61B2090/3782 , A61B2090/395 , A61B2218/002 , A61B2218/007 , A61M25/0041 , A61M25/0084 , A61M25/04 , A61M25/1002 , A61M25/1011 , A61M2025/0293 , A61M2025/1072 , A61N1/06 , A61N1/362 , A61N7/02
摘要： An ablating device has a cover which holds an interface material such as a gel. The cover contains the interface material during initial placement of the device. The ablating device may also have a removable tip or a membrane filled with fluid. In still another aspect, the ablating device may be submerged in liquid during operation.

4. 发明授权

US08140164B2 Therapeutic diaphragm stimulation device and method 有权
标题翻译：治疗性膜片刺激装置及方法
公开(公告)号：US08140164B2
公开(公告)日：2012-03-20
申请号：US11981342
申请日：2007-10-31
申请人： Amir J. Tehrani , Rose Province , Alan Schwartz , David Hillman , Peter Eastwood , David Ligon , Chang Lee , Drew Hoffmann , Amy Michelle Goodman
发明人： Amir J. Tehrani , Rose Province , Alan Schwartz , David Hillman , Peter Eastwood , David Ligon , Chang Lee , Drew Hoffmann , Amy Michelle Goodman
IPC分类号： A61N1/36
CPC分类号： A61N1/3601 , A61B5/0488 , A61B5/08 , A61B5/4818 , A61B5/7264 , A61N1/08
摘要： A device and method for treating a variety of conditions, disorders or diseases with diaphragm/phrenic nerve stimulation is provided.
摘要翻译：提供了一种用于治疗具有隔膜/膈神经刺激的各种病症，疾病或疾病的装置和方法。

5. 发明授权

US5385578A Electrical connection for medical electrical stimulation electrodes 失效
标题翻译：医用电刺激电极的电气连接
公开(公告)号：US5385578A
公开(公告)日：1995-01-31
申请号：US18832
申请日：1993-02-18
申请人： M. Elizabeth Bush , Drew Hoffmann , M. Dean Matthews , Pedro G. Medrano
发明人： M. Elizabeth Bush , Drew Hoffmann , M. Dean Matthews , Pedro G. Medrano
IPC分类号： A61N1/05 , A61N1/00
CPC分类号： A61N1/056
摘要： An improved endocardial lead for electrocardial stimulation includes a sleeve that has a face surface. A conductor fitted into the sleeve, such that a distal end of the conductor passes completely through the sleeve, past the face surface, is electrically and mechanically connected to the face surface of the sleeve by mechanical means, e.g. crimping, and/or through the application of heat, e.g. welding or brazing. An electrode is integrated with the sleeve along an outer sleeve surface. A highly reliable, redundant joint is thereby provided between the sleeve and the conductor that secures the conductor against movement and therefore minimizes stress placed on the conductor, preventing fatigue to the conductor at the joint. A sleeve made in accordance with the present invention provides the narrowest and shortest possible conductor/electrode joint to minimize impact on the patient, while at the same time providing an endocardial lead that has excellent electrical properties, mechanical stability, and ease of manufacture, and that may be made from any desired material to thereby take advantage of new and/or improved materials.
摘要翻译：用于心电图刺激的改进的心内膜导联包括具有面部表面的套筒。导体装配到套筒中，使得导体的远端完全穿过套筒穿过面表面，通过机械装置电气地和机械地连接到套筒的表面。卷曲和/或通过施加热，例如，焊接或钎焊。电极与套筒沿着外套筒表面一体化。因此，在套筒和导体之间提供了高度可靠的冗余接头，其固定住导体免受运动，从而使放置在导体上的应力最小化，防止接头处的导体疲劳。根据本发明制造的套筒提供最窄和最短的导体/电极接头，以最小化对患者的影响，同时提供具有优异电气性能，机械稳定性和易于制造的心内膜导联，以及其可以由任何期望的材料制成，从而利用新的和/或改进的材料。

6. 发明申请

US20080161878A1 Device and method to for independently stimulating hemidiaphragms 审中-公开
标题翻译：用于独立刺激膈肌的装置和方法
公开(公告)号：US20080161878A1
公开(公告)日：2008-07-03
申请号：US12005198
申请日：2007-12-26
申请人： Amir J. Tehrani , Rose Province , David Ligon , Amy Goodman , Chang Lee , Drew Hoffmann
发明人： Amir J. Tehrani , Rose Province , David Ligon , Amy Goodman , Chang Lee , Drew Hoffmann
IPC分类号： A61N1/36
CPC分类号： A61N1/3601 , A61B5/0488 , A61B5/08 , A61B5/4818 , A61B5/7264 , A61N1/08
摘要： A device and method for treating a subject is provided where electrical stimulation may be separately provided to each hemidiaphragm to cause diaphragm contraction. Fatigue may be avoided among other possible benefits. Each hemidiaphragm may also be stimulated with different stimulation parameters. Stimulation may be smoothly transitioned between hemidiaphragms. Such stimulation may provide an increase in functional residual capacity or other therapeutic effects.
摘要翻译：提供了一种用于治疗受试者的装置和方法，其中电刺激可以单独提供给每个膈肌以引起隔膜收缩。可能会避免疲劳和其他可能的好处。每个膈肌也可以用不同的刺激参数刺激。刺激可以在平板之间平滑过渡。这种刺激可以提供功能性残留能力或其它治疗效果。

7. 发明授权

US07069069B2 Implantable cardiac device for and method of monitoring progression or regression of heart disease by quantifying morphological features 失效
标题翻译：通过量化形态学特征可植入心脏装置和监测心脏病进展或消退的方法
公开(公告)号：US07069069B2
公开(公告)日：2006-06-27
申请号：US10094929
申请日：2001-12-06
申请人： Matthew G. Fishler , Eric Falkenberg , Drew Hoffmann
发明人： Matthew G. Fishler , Eric Falkenberg , Drew Hoffmann
IPC分类号： A61B5/0472
CPC分类号： A61B5/0031 , A61B5/0006 , A61B5/0452
摘要： An implantable cardiac device and method provides for monitoring a progression or regression in heart disease during an extended time period. A sensor generates an electrogram signal representing electrical activity of a patient's heart. From the generated electrogram signal, a processor determines morphology measurements wherein the morphology measurements indicate a progression or regression in the heart disease. The morphology measurements are stored in a memory during the extended period of time. A telemetry circuit transmits the stored morphology measurements to an external receiver for retrieval or display. The morphology measurements may be of electrogram intrinsic activity or evoked response activity characteristics.
摘要翻译：可植入心脏装置和方法提供在延长的时间段内监测心脏病的进展或消退。传感器产生表示患者心脏的电活动的电描记图信号。根据生成的电描记图信号，处理器确定形态学测量，其中形态学测量指示心脏病的进展或消退。形态测量在长时间内存储在存储器中。遥测电路将存储的形态测量值传输到外部接收器以进行检索或显示。形态学测量可以是电描记图内在活性或诱发反应活性特征。

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