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    • 1. 发明授权
    • Process for preparing water-soluble alkyd resins
    • 制备水溶性醇酸树脂的方法
    • US4200560A
    • 1980-04-29
    • US895560
    • 1978-04-12
    • Masyoshi KuboMichio NakanishiShoji Watanabe
    • Masyoshi KuboMichio NakanishiShoji Watanabe
    • C08G63/42C08G63/48C09D167/00C08L67/08C08G63/22C08L67/02
    • C08G63/42C08G63/48C08K5/34C09D167/00Y10T428/31794
    • A process for preparing a water-soluble alkyd resin, which comprises(1) reacting(i) at least one of(a) a 1,2-epoxyalkane containing 6 to 28 carbon atoms,(b) a straight-chain internal epoxyalkane containing 6 to 20 carbon atoms,(c) a mixture of one or more of the 1,2-epoxyalkane (a) and/or the internal epoxyalkane (b), or(d) a mixture of one or more of the 1,2-epoxyalkane (a) and/or the internal epoxyalkane (b) and an unsaturated fatty acid containing 12 to 18 carbon atoms in a molar ratio of about 4:1 to about 2:1 of the 1,2-epoxyalkane (a) and/or the internal epoxyalkane (b) to the unsaturated fatty acid;with(ii) at least one of(a') an aromatic carboxyl compound selected from the group consisting essentially of phthalic anhydride, isophthalic acid, terephthalic acid, an ester of isophthalic acid and an ester of terephthalic acid,(b') a mixture of two or more of the aromatic carboxyl compounds (a'), or(c') a mixture of one or more of the aromatic carboxylic compounds (a') and an aliphatic dicarboxylic acid having 3 or more carbon atoms or an anhydride thereof; and(iii) a polyhydric alcohol containing 2 to 10 carbon atomsto form a polyester containing hydroxyl groups and having an acid value of about 5 or less, a hydroxyl value of about 40 to about 200 and an average molecular weight of about 600 to about 2,500;(2) reacting the hydroxyl groups of the polyester with an aromatic polycarboxylic acid anhydride to adjust the acid value of the polyester to about 25 to about 80 and form a carboxyl group-containing alkyd resin; and(3) neutralizing the carboxyl group-containing alkyd resin with a base.
    • 一种制备水溶性醇酸树脂的方法,其包括(1)(i)使(a)含有6至28个碳原子的1,2-环氧烷烃中的至少一种(b)直链内部环氧烷烃 6至20个碳原子,(c)1,2-环氧烷烃(a)和/或内部环氧烷烃(b)中的一种或多种的混合物,或(d)1,2 - 环氧烷烃(a)和/或内部环氧烷烃(b)和含有12至18个碳原子的不饱和脂肪酸,其摩尔比约为1,2-环氧烷(a)的约4:1至约2:1,和 /或内部环氧烷烃(b)与不饱和脂肪酸反应; 与(ii)至少一种(a')芳族羧基化合物,其选自基本上由邻苯二甲酸酐,间苯二甲酸,对苯二甲酸,间苯二甲酸的酯和对苯二甲酸的酯,(b')混合物 的芳族羧酸化合物(a')或(c')中的一种或多种芳族羧酸化合物(a')和具有3个或更多个碳原子的脂族二羧酸或其酸酐的混合物; 和(iii)含有2至10个碳原子的多元醇,以形成含羟基并具有约5或更小的酸值,约40至约200的羟基值和约600至约平均分子量的聚酯 2,500; (2)使聚酯的羟基与芳族多羧酸酐反应,将聚酯的酸值调节至约25〜约80,形成含羧基的醇酸树脂; 和(3)用碱中和含羧基的醇酸树脂。
    • 2. 发明授权
    • Thermoplastic polyester resin, production of same, and orthopedic cast
material produced therefrom
    • 热塑性聚酯树脂,其生产方法以及由此生产的矫形铸造材料
    • US4404333A
    • 1983-09-13
    • US438954
    • 1982-11-03
    • Shoji WatanabeMichio Nakanishi
    • Shoji WatanabeMichio Nakanishi
    • A61L15/12C08G63/60C08G63/66C08F283/00C08G63/76
    • C08G63/66A61L15/12C08G63/60Y10T428/31786
    • New thermoplastic polyester resins having a low melting point which are useful as a molding material, especially as an orthopedic cast material; said resin having the formula (I):[A].sub.1 [B].sub.m [C].sub.n (I)where A denotes a residue of a straight or branched aliphatic dicarboxylic acid having 4 to 12 or 36 carbon atoms; B denotes a residue of a straight or branched aliphatic diol having 2 to 18 carbon atoms; C denotes a residue of 6-hydroxycaproic acid; these residues are linked through the ester bond and distributed randomly and/or in block in the molecule; 1, m, and n each has a value greater than 0; the residue of the 6-hydroxycaproic acid is 60 to 98 wt % and the sum of the residues of the aliphatic dicarboxylic acid and aliphatic diol is 40 to 2 wt %; the residue of the aliphatic dicarboxylic acid and the residue of the aliphatic diol are present in equimolar amount; and having a number-average molecular weight of 5,000 to 200,000.
    • 具有低熔点的新型热塑性聚酯树脂,其可用作模制材料,特别是作为矫形铸造材料; 所述具有式(I)的树脂:[A] 1 [B] m [C] n(I)其中A表示具有4至12或36个碳原子的直链或支链脂族二羧酸的残基; B表示具有2至18个碳原子的直链或支链脂族二醇的残基; C表示6-羟基己酸的残基; 这些残基通过酯键连接并在分子中随机和/或嵌段分布; 1,m和n各自具有大于0的值; 6-羟基己酸的残基为60〜98重量%,脂肪族二羧酸和脂肪族二醇的残基之和为40〜2重量%。 脂族二羧酸的残基和脂肪族二醇的残基以等摩尔量存在; 数均分子量为5000〜200000。
    • 6. 发明授权
    • Triazolothienodiazepine compounds
    • 三唑并噻吩并二氮杂类化合物
    • US3965111A
    • 1976-06-22
    • US301910
    • 1972-10-30
    • Michio NakanishiKazuhiko ArakiTetsuya TaharaMasami Shiroki
    • Michio NakanishiKazuhiko ArakiTetsuya TaharaMasami Shiroki
    • A61K31/55A61P23/00A61P25/08A61P25/20C07D495/04C07D495/14
    • C07D495/04C07D495/14
    • Triazolothienodiazepine compounds of the formula; ##SPC1##Wherein X is a member selected from the group consisting of a hydrogen atom, a methyl group, a methoxy group and a trifluoromethyl group; each of R.sup.1 and R.sup.2 is a member selected from the group consisting of a hydrogen atom and an alkyl group having 1 to 4 carbon atoms, or R.sup.1 and R.sup.2 together can form a tetramethylene group, i.e.--(CH.sub.2).sub.4 --; R is a member selected from the group consisting of a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, --CONHR.sup.3 (R.sup.3 being an alkyl group having 1 to 4 carbon atoms) and -alk-N(R.sup. 4)(R.sup.5) (each of R.sup.4 and R.sup.5 being a member selected from the group consisting of a hydrogen atom and an alkyl group having 1 to 4 carbon atoms, or R.sup.4 and R.sup.5 and N can form a heterocyclic ring; and alk being an alkylene group having 2 to 4 carbon atoms); and Z is a member selected from the group consisting of an oxygen atom and a sulphur atom; and the pharmaceutically acceptable acid addition salts thereof are disclosed. These compounds are useful as minor tranquillizers (anti-anxiety drugs), sleep inducers, and anti-epileptics.
    • 三唑并噻吩并二氮杂化合物; 其中X是选自氢原子,甲基,甲氧基和三氟甲基的成员; R 1和R 2各自为选自氢原子和具有1至4个碳原子的烷基的成员,或者R 1和R 2一起可以形成四亚甲基,即 - (CH 2)4 - ; R是选自氢原子,具有1至4个碳原子的烷基,-CONHR 3(R 3是具有1至4个碳原子的烷基)和-alk-N(R 4)(R 5) )(R4和R5各自为氢原子和碳原子数1〜4的烷基,R4,R5和N可以形成杂环,烷基为2以上的亚烷基 至4个碳原子); Z为选自氧原子和硫原子的成员; 及其药学上可接受的酸加成盐。 这些化合物可用作轻度镇定剂(抗焦虑药),睡眠诱导剂和抗癫痫药。