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    • 1. 发明授权
    • Electromagnetic actuator
    • 电磁执行器
    • US07358629B2
    • 2008-04-15
    • US10569778
    • 2004-08-27
    • Masami YamamotoAkihiro ItoMasato TanakaShinji MorinagaTetsuya Iwamoto
    • Masami YamamotoAkihiro ItoMasato TanakaShinji MorinagaTetsuya Iwamoto
    • H02K37/14H02K1/00
    • H02K37/16H02K1/141
    • The rotational torque of an electromagnetic actuator having a stator and rotor, such as a stepping motor, is increased.The electromagnetic actuator includes a rotor (30) having multiple magnetic poles (Nr1, Nr2, Nr3, Nr4, Nr5, Sr1, Sr2, Sr3, Sr4, Sr5) on a circumferential surface (31) and a plurality of stators (10, 20) in an electromagnet form. The stator (10, 20) has a pair of magnetic poles (13, 14, 23, 24) facing the circumferential surface (31) of the rotor (30), and an auxiliary yoke (40, 50) made of a soft magnetic material member extending in a circumferential direction (A) over an angular range (γ1, γ2) larger than a spread angle (α) of the magnetic poles (Nr, Sr) of the rotor (30) in the circumferential direction (A) is provided between the pair of magnetic poles (13, 14, 23, 24).
    • 具有诸如步进电机的定子和转子的电磁致动器的转矩增加。 电磁致动器包括具有多个磁极(Nr 1,N 2,N 3,N 3,N 4)的转子(30) / SUB,Nr 5,Sr 1,Sr 2,Sr 3,Sr 4, / SUB>,Sr 5),并且以电磁体形式存在多个定子(10,20)。 定子(10,20)具有面对转子(30)的圆周面(31)的一对磁极(13,14,23,24)和由软磁体制成的辅助磁轭(40,50) 材料构件在大于圆周方向(A)上的转子(30)的磁极(Nr,Sr)的扩展角(α)的角度范围(γ1,γ2)上沿圆周方向(A)延伸, 设置在所述一对磁极(13,14,23,24)之间。
    • 2. 发明申请
    • Electromagnetic actuator
    • 电磁执行器
    • US20070018513A1
    • 2007-01-25
    • US10569778
    • 2004-08-27
    • Masami YamamotoAkihiro ItoMasato TanakaShinji MorinagaTetsuya Iwamoto
    • Masami YamamotoAkihiro ItoMasato TanakaShinji MorinagaTetsuya Iwamoto
    • H02K37/14H02K1/00
    • H02K37/16H02K1/141
    • The rotational torque of an electromagnetic actuator having a stator and rotor, such as a stepping motor, is increased. The electromagnetic actuator includes a rotor (30) having multiple magnetic poles (Nr1, Nr2, Nr3, Nr4, Nr5, Sr1, Sr2, Sr3, Sr4, Sr5) on a circumferential surface (31) and a plurality of stators (10, 20) in an electromagnet form. The stator (10, 20) has a pair of magnetic poles (13, 14, 23, 24) facing the circumferential surface (31) of the rotor (30), and an auxiliary yoke (40, 50) made of a soft magnetic material member extending in a circumferential direction (A) over an angular range (γ1, γ2) larger than a spread angle (α) of the magnetic poles (Nr, Sr) of the rotor (30) in the circumferential direction (A) is provided between the pair of magnetic poles (13, 14, 23, 24).
    • 具有诸如步进电机的定子和转子的电磁致动器的转矩增加。 电磁致动器包括具有多个磁极(Nr 1,N 2,N 3,N 3,N 4)的转子(30) / SUB,Nr 5,Sr 1,Sr 2,Sr 3,Sr 4, / SUB>,Sr 5),并且以电磁体形式存在多个定子(10,20)。 定子(10,20)具有面对转子(30)的圆周面(31)的一对磁极(13,14,23,24)和由软磁体制成的辅助磁轭(40,50) 材料构件在大于圆周方向(A)上的转子(30)的磁极(Nr,Sr)的扩展角(α)的角度范围(γ1,γ2)上沿圆周方向(A)延伸, 设置在所述一对磁极(13,14,23,24)之间。
    • 7. 发明授权
    • Method for assaying histone methylation enzyme activity
    • 测定组蛋白甲基化酶活性的方法
    • US09012166B2
    • 2015-04-21
    • US13639334
    • 2011-04-15
    • Norikazu NishinoYasushi TakemotoAkihiro ItoMinoru Yoshida
    • Norikazu NishinoYasushi TakemotoAkihiro ItoMinoru Yoshida
    • G01N21/78C12Q1/37C12Q1/48G01N33/68C07D311/18C07D311/82C07D473/32
    • C12Q1/37C07D311/18C07D311/82C07D473/32C12Q1/48G01N33/6875G01N2500/00Y02P20/55
    • Provided are a method for measuring histone methyltransferase activity, a method for screening for compounds that inhibit histone methyltransferase activity, a reagent kit for measuring histone methyltransferase activity, and a kit for screening for compounds that inhibit histone methyltransferase activity. A substrate compound represented by general formula (I): R1-X-K-R2 (I), or a salt thereof, wherein R1 represents a hydrogen atom or a protecting group for an amino terminus; X represents a peptide consisting of 0 or 1 or more amino acid residues; K represents a lysine residue; and R2 represents a dye label linked via an amide bond to the carbonyl terminus of a lysine residue, wherein the cleavage of the amide bond by peptidase changes the fluorescence property or chromogenic property of the dye label, and the methylation of the ε amino group of the lysine residue by the histone methyltransferase decreases susceptibility to peptidase, is used.
    • 提供了测定组蛋白甲基转移酶活性的方法,用于筛选抑制组蛋白甲基转移酶活性的化合物的方法,用于测定组蛋白甲基转移酶活性的试剂盒和用于筛选抑制组蛋白甲基转移酶活性的化合物的试剂盒。 由通式(I)表示的底物化合物:R1-X-K-R2(I)或其盐,其中R1表示氢原子或氨基末端的保护基; X表示由0或1个或更多个氨基酸残基组成的肽; K表示赖氨酸残基; R2表示通过酰胺键与赖氨酸残基的羰基末端连接的染料标记,其中通过肽酶切割酰胺键改变染料标记的荧光性质或显色性质,以及染料标记的甲基化。 使用组蛋白甲基转移酶的赖氨酸残基的氨基降低对肽酶的易感性。