专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US06563634B2 Microscope with aberration correcting function 有权
标题翻译：具有像差校正功能的显微镜
公开(公告)号：US06563634B2
公开(公告)日：2003-05-13
申请号：US09951871
申请日：2001-09-13
申请人： Masakazu Shimada , Yoshihiro Shimada , Hisao Kitagawa
发明人： Masakazu Shimada , Yoshihiro Shimada , Hisao Kitagawa
IPC分类号： G02B2100
CPC分类号： G02B21/241
摘要： A microscope according to the invention comprises an aberration correcting objective lens facing a specimen and having an aberration correcting lens correcting an aberration due to an error in the thickness of a cover, a Petri dish or a slide glass; a moving amount detector detecting moving amount of the aberration correcting lens; a focusing unit moving the specimen; a driver unit driving the focusing unit; and an arithmetic unit obtaining a defocus amount based on a moving amount detected by the moving amount detector. When the aberration correcting lens is moved, the specimen is put out of focus. On the basis of a defocus amount obtained by the arithmetic unit, the driver unit drives the focusing unit so that the lens may focus on the specimen.
摘要翻译：根据本发明的显微镜包括面向样本的像差校正物镜，并且具有校正由盖，培养皿或载玻片的厚度误差引起的像差的像差校正透镜; 移动量检测器，检测像差校正透镜的移动量; 移动样本的聚焦单元; 驱动聚焦单元的驱动单元; 以及算术单元，基于由移动量检测器检测到的移动量获得散焦量。当像差校正透镜移动时，样本失焦。基于由运算单元获得的散焦量，驱动单元驱动聚焦单元，使得透镜可以聚焦在样本上。

2. 发明授权

US06297904B1 Inverted confocal microscope 失效
标题翻译：倒置共聚焦显微镜
公开(公告)号：US06297904B1
公开(公告)日：2001-10-02
申请号：US09400410
申请日：1999-09-21
申请人： Hisao Kitagawa , Yasushi Aono , Kazuhiko Osa , Yosuke Kishi , Yoshihiro Shimada
发明人： Hisao Kitagawa , Yasushi Aono , Kazuhiko Osa , Yosuke Kishi , Yoshihiro Shimada
IPC分类号： G02B2100
CPC分类号： G02B21/0052 , G02B21/0048 , G02B21/0076 , G02B21/0088
摘要： An inverted microscope is provided that reflects an observation light passing through an image-formation optical system upward using at least one reflection optical system and that leads the observation light to an observation path. The inverted microscope includes a confocal scanner arranged at an image surface position of the image-formation optical system, a light source for applying light onto a sample through the confocal scanner and the image-formation optical system, and a confocal image formation optical system that leads the light passing through the confocal scanner to the sample through the image-formation optical system, returns a return light from the sample to the confocal scanner along a route opposite to that for leading the light to the sample, and obtains a confocal image. A confocal observation optical system is also provided for leading the return light from the sample passing through the optical scanner to the observation optical path.
摘要翻译：提供一种倒置显微镜，其使用至少一个反射光学系统向上反射通过图像形成光学系统的观察光，并将观察光引导到观察路径。倒置显微镜包括布置在图像形成光学系统的图像表面位置处的共焦扫描器，用于通过共焦扫描器和图像形成光学系统将光施加到样本上的光源，以及共焦图像形成光学系统，其中将通过共聚焦扫描器的光引导到通过图像形成光学系统的样品，沿着与将光导向样品的路线相反的路线从样品返回到共聚焦扫描器，并获得共聚焦图像。还提供了共焦观察光学系统，用于将来自通过光学扫描器的样品的返回光引导到观察光路。

3. 发明授权

US4629862A Sample heater for use in microscopes 失效
标题翻译：用于显微镜的样品加热器
公开(公告)号：US4629862A
公开(公告)日：1986-12-16
申请号：US671732
申请日：1984-11-15
申请人： Hisao Kitagawa , Yasuo Inoue , Tadafumi Fujihara , Itaru Endo , Yoshihiro Shimada
发明人： Hisao Kitagawa , Yasuo Inoue , Tadafumi Fujihara , Itaru Endo , Yoshihiro Shimada
IPC分类号： G02B21/30 , H05B3/22
CPC分类号： G02B21/30 , C12M41/12 , C12M41/36
摘要： A heater for microscopes for heating a sample and maintaining the sample, which is mounted on a platform of the microscope, at a preset temperature during observation of the sample. The heater includes a platform for supporting thereon a sample container and a heater for heating at least part of the platform. A first heater box is fitted, open end down, over the platform and is connected thereto to form a first space which surrounds the sample container. A second heater box is then fitted over the first heater box in such a manner that a second space which surrounds the first heater box is formed. Heater means are provided for heating the second space. Accordingly, the temperatures in the first space and in the second space can be controlled independently to achieve better control over the temperature of the sample which is to be observed and to control condensation which may otherwise form in the sample holding container.
摘要翻译：用于在样品观察期间加热样品并将安装在显微镜的平台上的样品保持在预设温度的显微镜加热器。加热器包括用于在其上支撑样品容器的平台和用于加热至少部分平台的加热器。第一加热箱被安装在平台上并向下开口，并与之相连，形成围绕样品容器的第一空间。然后将第二加热器盒以这样的方式装配在第一加热器盒上，使得形成围绕第一加热箱的第二空间。提供加热装置用于加热第二空间。因此，可以独立地控制第一空间和第二空间中的温度，以便更好地控制待观察的样品的温度并控制另外可能在样品保持容器中形成的冷凝。

4. 发明授权

US4732485A Optical surface profile measuring device 失效
标题翻译：光学表面轮廓测量装置
公开(公告)号：US4732485A
公开(公告)日：1988-03-22
申请号：US852845
申请日：1986-04-16
申请人： Terumasa Morita , Noriyuki Miyahara , Hisao Kitagawa
发明人： Terumasa Morita , Noriyuki Miyahara , Hisao Kitagawa
IPC分类号： G01B11/24
CPC分类号： G01B11/24
摘要： An optical surface profile measuring device adapted to be able to simultaneously or substantially simultaneously measure a same part on the surface of an object to be measured with two different measuring ranges by combining a surface profile measuring device of a high resolving power using the critical angle method with a surface profile measuring device having a wide measuring range using the astigmatism method, in order to facilitate the setting of a detecting head within a measuring range while maintaining a high resolving power and to enable to measure automatically regardless of the state of the measured surface. This optical surface profile measuring device is provided with an iris stop or liquid crystal shutter capable of varying the numerical aperture behind an objective lens to allow the free setting of the resolving power or the measuring range, and further provided with an aperture stop to make the numerical aperture on the detecting side smaller than the numerical aperture on the projecting side to thereby obtain the proper measuring result even if the measured surface inclines with respect to the optical axis.
摘要翻译：一种光学表面轮廓测量装置，其适于能够通过使用临界角方法组合具有高分辨率的表面轮廓测量装置来同时或基本上同时测量待测对象的表面上的相同部分，具有两个不同的测量范围具有使用散光法的宽测量范围的表面轮廓测量装置，以便于在保持高分辨能力的同时在检测范围内设置检测头，并且能够自动测量而不管测量表面的状态如何。该光学表面轮廓测量装置设置有能够改变物镜后面的数值孔径的光圈停止或液晶快门，以允许分辨力或测量范围的自由设定，并且还设置有孔径光阑，以使检测侧的数值孔径小于突出侧的数值孔径，从而即使测量的表面相对于光轴倾斜，也能获得适当的测量结果。

5. 发明授权

US06191885B1 Confocal microscope apparatus and photographing apparatus for confocal microscope 有权
标题翻译：共焦显微镜装置和共焦显微镜摄影装置
公开(公告)号：US06191885B1
公开(公告)日：2001-02-20
申请号：US09400409
申请日：1999-09-21
申请人： Hisao Kitagawa
发明人： Hisao Kitagawa
IPC分类号： G02B2100
CPC分类号： G02B21/0044 , G02B21/008
摘要： A confocal microscope apparatus includes a disk scanner for scanning a specimen with a laser beam, and camera main body for photographing a still image. An exposure time calculation circuit is arranged to generates an exposure time signal for the camera main body. A rotation sensor, a scan track start point/end point determination circuit, and a rotation period calculation circuit are arranged to generate a rotational period signal for the disk scanner. A comparator compares the exposure time signal with the rotational period signal, so that a motor controller and a motor driver control rotation of a motor of the disk scanner by a comparison output from the comparator.
摘要翻译：共聚焦显微镜装置包括用于用激光束扫描样本的盘扫描器和用于拍摄静止图像的照相机主体。布置曝光时间计算电路以产生相机主体的曝光时间信号。旋转传感器，扫描轨迹起始点/终点确定电路和旋转周期计算电路被布置成产生用于盘扫描器的旋转周期信号。比较器将曝光时间信号与旋转周期信号进行比较，使得电动机控制器和电动机驱动器通过比较器的比较输出来控制盘扫描器的电动机的旋转。

6. 再颁专利

USRE39751E1 Confocal microscope apparatus and photographing apparatus for confocal microscope 有权
标题翻译：共焦显微镜装置和共焦显微镜摄影装置
公开(公告)号：USRE39751E1
公开(公告)日：2007-07-31
申请号：US10370366
申请日：2003-02-19
申请人： Hisao Kitagawa
发明人： Hisao Kitagawa
IPC分类号： G02B21/06
CPC分类号： G02B21/0044 , G02B21/008
摘要： A confocal microscope apparatus includes a disk scanner for scanning a specimen with a laser beam, and camera main body for photographing a still image. An exposure time calculation circuit is arranged to generates an exposure time signal for the camera main body. A rotation sensor, a scan track start point/end point determination circuit, and a rotation period calculation circuit are arranged to generate a rotational period signal for the disk scanner. A comparator compares the exposure time signal with the rotational period signal, so that a motor controller and a motor driver control rotation of a motor of the disk scanner by a comparison output from the comparator.
摘要翻译：共聚焦显微镜装置包括用于用激光束扫描样本的盘扫描器和用于拍摄静止图像的照相机主体。布置曝光时间计算电路以产生相机主体的曝光时间信号。旋转传感器，扫描轨迹起始点/终点确定电路和旋转周期计算电路被布置成产生用于盘扫描器的旋转周期信号。比较器将曝光时间信号与旋转周期信号进行比较，使得电动机控制器和电动机驱动器通过比较器的比较输出来控制盘扫描器的电动机的旋转。

7. 再颁专利

USRE41984E1 Still-picture acquisition method and apparatus applied to microscope 有权
标题翻译：静态图像采集方法和装置应用于显微镜
公开(公告)号：USRE41984E1
公开(公告)日：2010-12-07
申请号：US10962258
申请日：2004-10-08
申请人： Hisao Kitagawa
发明人： Hisao Kitagawa
IPC分类号： H04N7/18
CPC分类号： H04N1/2112 , G02B21/365 , H04N1/2133 , H04N1/215 , H04N7/18 , H04N2201/0079
摘要： A still-picture acquisition section in a computer selects a brightness-periodically-varying portion of image data of a living cell like a cardiac cell, as a sample, which makes a self-ordered periodic motion, monitors a change in brightness, generates a trigger signal at the timing at which the value of the brightness exceeds a specific threshold value, causes a camera body to repeatedly pick up the image of the living cell after a predetermined delay time, and then averages the picked-up images. This makes it possible to acquire as high-quality still pictures the instantaneous status of a living cell which varies with time in accordance with the application of external stimulation or the in-vivo order.
摘要翻译：计算机中的静止图像获取部分选择像心脏细胞一样的活细胞的图像数据的亮度周期性变化部分作为进行自定期周期运动的样本，监视亮度变化，生成在亮度值超过特定阈值的定时触发信号，使照相机体在预定的延迟时间之后重复地摄取活细胞的图像，然后平均拍摄的图像。这使得可以获得根据外部刺激或体内顺序的应用随时间变化的活细胞的瞬时状态的高质量静态图像。

8. 发明授权

US06462771B1 Still-picture acquisition method and apparatus applied to microscope 有权
标题翻译：静态图像采集方法和装置应用于显微镜
公开(公告)号：US06462771B1
公开(公告)日：2002-10-08
申请号：US09532066
申请日：2000-03-21
申请人： Hisao Kitagawa
发明人： Hisao Kitagawa
IPC分类号： H04N718
CPC分类号： H04N1/2112 , G02B21/365 , H04N1/2133 , H04N1/215 , H04N7/18 , H04N2201/0079
摘要： A still-picture acquisition section in a computer selects a brightness-periodically-varying portion of image data of a living cell like a cardiac cell, as a sample, which makes a self-ordered periodic motion, monitors a change in brightness, generates a trigger signal at the timing at which the value of the brightness exceeds a specific threshold value, causes a camera body to repeatedly pick up the image of the living cell after a predetermined delay time, and then averages the picked-up images. This makes it possible to acquire as high-quality still pictures the instantaneous status of a living cell which varies with time in accordance with the application of external stimulation or the in-vivo order.
摘要翻译：计算机中的静止图像获取部分选择像心脏细胞一样的活细胞的图像数据的亮度周期性变化部分作为进行自定期周期运动的样本，监视亮度变化，生成在亮度值超过特定阈值的定时触发信号，使照相机体在预定的延迟时间之后重复地摄取活细胞的图像，然后平均拍摄的图像。这使得可以获得根据外部刺激或体内顺序的应用随时间变化的活细胞的瞬时状态的高质量静态图像。

9. 发明授权

US5334830A Scanning optical microscope having a compact confocal optical system for adjusting position of aperture 失效
标题翻译：扫描光学显微镜具有用于调节孔径位置的紧凑型共焦光学系统
公开(公告)号：US5334830A
公开(公告)日：1994-08-02
申请号：US004458
申请日：1993-01-14
申请人： Hiroya Fukuyama , Hisao Kitagawa , Mitsunori Yamamoto , Shingo Kashima
发明人： Hiroya Fukuyama , Hisao Kitagawa , Mitsunori Yamamoto , Shingo Kashima
IPC分类号： G02B21/00 , H01J3/14
CPC分类号： G02B21/0032 , G02B21/0048 , G02B21/0076
摘要： A laser beam from a light source is reflected by a beam splitter and two galvanomirrors, and enters a pupil projection lens. The beam passing through the lens forms a spot on an image plane of an objective. This spot is two-dimensionally scanned by shaking the galvanomirrors with respect to their axes perpendicular to each other. Reflected light or fluorescence from a sample is returned to the beam splitter through the same path, passes through it, and is then reflected by a mirror. This optical system includes an optical unit which can be inserted/removed therein/therefrom. When the optical unit is removed, the optical system serves as a confocal optical system. When the optical unit is inserted, the optical system serves as a nonconfocal optical system. In the confocal optical system, the beam from the mirror enters a condenser, converges, passes through an iris and enters a photomultiplier tuber. The condenser includes a convex lens and a concave lens. In the nonconfocal optical system, the beam from the mirror enters a condenser, converges and is focused on the iris to a spot. The beam passing through the iris enters the photomultiplier tube.
摘要翻译：来自光源的激光束被分束器和两个电流镜反射，并且进入瞳孔投影透镜。穿过透镜的光束在物镜的图像平面上形成一个点。通过相对于它们彼此垂直的轴线摇动电镜镜来对该点进行二维扫描。来自样品的反射光或荧光通过相同的路径返回到分束器，通过它，然后被反射镜反射。该光学系统包括可以在其中插入/移除的光学单元。当光学单元被去除时，光学系统用作共焦光学系统。当插入光学单元时，光学系统用作非共焦光学系统。在共焦光学系统中，来自镜子的光束进入冷凝器，会聚，通过虹膜并进入光电倍增块。冷凝器包括凸透镜和凹透镜。在非共焦光学系统中，来自反射镜的光束进入聚光器，会聚并聚焦在虹膜上。通过虹膜的光束进入光电倍增管。

10. 发明授权

US4643550A Photographing indication device for microscopes 失效
标题翻译：显微镜摄影指示装置
公开(公告)号：US4643550A
公开(公告)日：1987-02-17
申请号：US719541
申请日：1985-04-03
申请人： Hisao Kitagawa , Yasuo Inoue
发明人： Hisao Kitagawa , Yasuo Inoue
IPC分类号： G02B21/00 , G02B21/06 , G02B21/36 , G02B27/32 , G02B27/34 , G03B17/20 , G03B17/48
CPC分类号： G03B17/20 , G02B21/361 , G02B27/34 , G03B17/48
摘要： A photographing indication device for microscopes comprising a transparent plate-shaped indication member arranged in the optical path of a microscope in such a manner that its surface including engraved indication lines is located at a position conjugate with the image surface of a photographing device, a plurality of light emitting means having different emission colors and arranged on the side of said indication member for illuminating said member, and control circuit equipped with variable resistor for glowing said light emitting means selectively and capable of controlling light intensity with variable resistor, thereby allowing said indication lines to be clearly distinguishable from an image to be observed and illuminated brightly and uniformly even during microscopy under the dark field illumination or reflecting fluorescence illumination.
摘要翻译：一种用于显微镜的拍摄指示装置，包括布置在显微镜的光路中的透明板状指示部件，使得其包括雕刻指示线的表面位于与拍摄装置的图像表面共轭的位置，多个具有不同发光颜色的发光装置，并且布置在所述指示部件的用于照亮所述部件的一侧，以及配备有可变电阻器的控制电路，用于选择性地发光所述发光装置并且能够用可变电阻器控制光强度，从而允许所述指示即使在暗场照明下的显微镜下也可以反射荧光照明，线条与待观察的图像和明亮均匀的照明清楚地区分开。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式