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1. 发明申请

US20080262385A1 Backflow Preventing Structure of a Blood Sampler, Luer Adapter, Blood Sampling Needle and Blood Sampling Holder 审中-公开
标题翻译：回流防止血液取样器，鲁尔适配器，血液取样针和血液取样架的结构
公开(公告)号：US20080262385A1
公开(公告)日：2008-10-23
申请号：US11596214
申请日：2005-05-16
申请人： Masahiro Nakaizumi , Ryusuke Okamoto
发明人： Masahiro Nakaizumi , Ryusuke Okamoto
IPC分类号： A61B5/153
CPC分类号： A61B5/154 , A61B5/15003 , A61B5/150221 , A61B5/150351 , A61B5/150389 , A61B5/150496 , A61B5/150572 , A61B5/150732
摘要： A backflow preventing structure of a blood sampler capable of preventing backflow of blood positively without causing a significant increase in the number of components and cost. The backflow preventing structure of a blood sampler comprises a hub (3) as a tubular body having an internal channel (3a) extending from a first end part (3b) toward the second end part (3c) side, and a bottomed tubular backflow preventing member (6) which is composed of a material having rubber elasticity and contained in the internal channel (3a), has an opening opened toward the first end part (3b), and is closed on the second end part (3c) side. Outer circumferential wall of the backflow preventing member (6) is secured liquidtightly to the inner wall of the internal channel (3a), and a cut (6c) is made in the backflow preventing member (6) at a part closer to the second end part side than the secured part.
摘要翻译：能够防止血液回流的血液取样器的回流防止结构，而不会导致部件数量的显着增加和成本。血液采样器的防回流结构包括作为管状体的轮毂（3），其具有从第一端部（3b）朝向第二端部（3c）侧延伸的内部通道（3a），底部由具有橡胶弹性并容纳在内部通道（3a）中的材料构成的管状防回流部件（6）具有朝向第一端部（3b）开口的开口，并且在第二端部（ 3 c）侧。防回流部件（6）的外周壁被液密地固定在内部通道（3a）的内壁上，并且在防逆流部件（6）的靠近第二端部侧比固定部分。

2. 发明申请

US20120203138A1 PLUG AND BODILY FLUID-COLLECTING INSTRUMENT SET 审中-公开
标题翻译： PLUG和BODILY流体收集仪器集
公开(公告)号：US20120203138A1
公开(公告)日：2012-08-09
申请号：US13502479
申请日：2011-01-27
申请人： Masatoshi Niunoya , Ryusuke Okamoto
发明人： Masatoshi Niunoya , Ryusuke Okamoto
IPC分类号： A61B5/15 , B65D41/02
CPC分类号： A61J1/1406 , A61B5/15003 , A61B5/150259 , A61B5/150351 , A61B5/150389 , A61B5/150473 , A61B5/150572 , A61B5/150732 , A61B5/154 , A61J1/2096 , B65D51/002
摘要： A plug that allows the plug body to be easily and reliably pierced through by a hollow bodily fluid collection needle, makes the bodily fluid collection needle difficult to draw back out of the plug body owing to a resilience of a sheath after the start of bodily fluid collection, and enables easy and reliable collection of the bodily fluid. The plug 1 is a plug for closing an opening end of a bodily fluid-collecting container 14 which is to be inserted into a tubular holder 11, and includes: a plug body 2 to be fixed to the opening end of the bodily fluid-collecting container 14; and a cover member 3 sheathed on the plug body 2 to cover an outer surface of the plug body 2, wherein the cover member 3 includes a side part 3c covering the outer surface of the plug body 2, and an outer surface of the side part 3c is provided with a protrusion 3k which protrudes radially outward of the side part 3c of the cover member 3 to come into contact with and give frictional resistance to an inner wall of the holder 11 upon insertion into the holder 11.
摘要翻译：允许插塞体容易且可靠地穿过中空的体液采集针的插头使得体液采集针难以从体液回流出来，这是由于体液开始后鞘的弹性收集，并且能够容易且可靠地收集体液。插头1是用于封闭要插入管状保持器11的体液收集容器14的开口端的插头，包括：固定在体液收集容器14的开口端的插塞体2 集装箱14; 以及覆盖在塞主体2上以覆盖插头主体2的外表面的盖构件3，其中，盖构件3包括覆盖插头主体2的外表面的侧部3c和侧部的外表面 3c设置有突出部3k，突出部3k从盖部件3的侧部3c径向向外突出，以便在插入保持器11时与保持器11的内壁接触并产生摩擦阻力。

3. 发明申请

US20070082370A1 Plasma or serum separation membrane and filter apparatus including the plasma or serum separation membrane 有权
标题翻译：血浆或血清分离膜和包括血浆或血清分离膜的过滤装置
公开(公告)号：US20070082370A1
公开(公告)日：2007-04-12
申请号：US11635239
申请日：2006-12-07
申请人： Katsuya Togawa , Ryusuke Okamoto , Hironobu Isogawa
发明人： Katsuya Togawa , Ryusuke Okamoto , Hironobu Isogawa
IPC分类号： G01N33/567 , C12M3/00
CPC分类号： B01D69/02 , B01D61/18 , B01L3/502 , B01L3/5082 , B01L2300/047 , B01L2300/0681 , B01L2400/0487 , G01N33/491 , Y10T436/11 , Y10T436/25 , Y10T436/25125 , Y10T436/25375 , Y10T436/255
摘要： A Plasma or serum separation membrane that enables omitting centrifugal separation, is free from hemolysis attributed to destruction of red blood cells and realizes easy and rapid separation of plasma or serum from blood; and a filter apparatus including the plasma or serum separation membrane. In particular, a plasma or serum separation membrane being a membrane for separation of plasma or serum from blood and having a void ratio of 30% or below; and a filter apparatus comprising a filter member capable of attaining movement of plasma swifter than movement of blood cells and a plasma or serum separation membrane connected in series with a rear side of the filter member.
摘要翻译：能够省略离心分离的血浆或血清分离膜不会因红细胞破坏引起溶血，并能实现血液或血清从血液中的轻松快速分离; 以及包括血浆或血清分离膜的过滤装置。特别地，血浆或血清分离膜是用于从血液中分离血浆或血清并具有30％或更低的空隙率的膜; 以及过滤器装置，其包括能够获得比等离子体更快速移动的过滤器构件，以及与过滤构件的后侧串联连接的血浆或血清分离膜。

4. 发明授权

US06821785B1 Vacuum sample collecting tube and method of collecting sample under vacuum 失效
标题翻译：真空采样管和真空收集样品的方法
公开(公告)号：US06821785B1
公开(公告)日：2004-11-23
申请号：US10009683
申请日：2002-02-22
申请人： Hideo Anraku , Ryusuke Okamoto
发明人： Hideo Anraku , Ryusuke Okamoto
IPC分类号： A61M532
CPC分类号： A61B5/154 , A61B5/15003 , A61B5/150221 , A61B5/150351 , A61B5/150389 , A61B5/150496 , A61B5/150732 , B01L3/502 , B01L3/5082 , B01L2200/16 , B01L2300/044 , B01L2300/0672 , B01L2300/0854 , B01L2400/0683
摘要： The present invention has for its object to provide a vacuum sampling tube which is capable of preventing a pretreating reagent accommodated in the vacuum sampling tube from entering the blood vessel and the like even in the event of a backflow of a specimen, such as blood, during vacuum sampling, such as vacuum blood collecting, and a vacuum sampling method.
摘要翻译：本发明的目的是提供一种真空采样管，其能够防止容纳在真空取样管中的预处理试剂即使在诸如血液的样品的回流的情况下也进入血管等，在真空采样中，例如真空采血，以及真空采样方法。

5. 发明授权

US06565814B1 CLOSURE STRUCTURE FOR VACUUM SPECIMEN COLLECTION CONTAINER, VACUUM SPECIMEN COLLECTION CONTAINER, VACUUM SPECIMEN COLLECTION SYSTEM, HOLDER FOR VACUUM SPECIMEN COLLECTION SYSTEM AND THERMOPLASTIC ELASTOMER COMPOSITION FOR FORMING CLOSURE STRUCTURE 失效
标题翻译：真空样品收集容器，真空样品收集容器，真空样品收集系统，真空样品收集系统保持器和形成闭合结构的热塑性弹性体组合物的闭合结构
公开(公告)号：US06565814B1
公开(公告)日：2003-05-20
申请号：US09622891
申请日：2000-08-30
申请人： Hideo Anraku , Ryusuke Okamoto
发明人： Hideo Anraku , Ryusuke Okamoto
IPC分类号： B01L300
CPC分类号： B01L3/50825
摘要： A closure structure is provided for a vacuum specimen collection container which can maintain a vacuum pressure within the specimen collection tube and which includes a needle cannula penetrating portion having needle hole sealability. The closure structure can be detachably fitted in an open end of a specimen collection container in an airtight manner to maintain a vacuum condition within the specimen collection container. The closure structure includes a grip section, a rubber elastic needle cannula penetrating portion disposed to fill up a through-hole in a grip section and a rubber elastic fitting portion configured to follow an interior surface profile of an open end of a specimen collection container, thereby to fit therein in a airtight fashion. The grip section has a higher rigidity relative to the needle cannula penetrating portion and the fitting portion. A tubular side wall of a grip section has on its inner side at least one raised portion or recessed portion to prevent kickback.
摘要翻译：为真空样本采集容器提供封闭结构，其能够保持样品收集管内的真空压力，并且其包括具有针孔密封性的针插管穿透部分。封闭结构可以以气密的方式可拆卸地装配在样本收集容器的开口端，以保持样本收集容器内的真空状态。封闭结构包括握持部分，设置成填充握持部分中的通孔的橡胶弹性针插管穿透部分和构造成跟随样本收集容器的开口端的内表面轮廓的橡胶弹性配合部分，从而以气密方式装配在其中。握持部具有相对于针插管穿透部和配合部的更高的刚性。把手部分的管状侧壁的内侧具有至少一个凸起部分或凹进部分，以防止反冲。

6. 发明授权

US5776357A Serum or plasma separating compositions 失效
标题翻译：血清或血浆分离组合物
公开(公告)号：US5776357A
公开(公告)日：1998-07-07
申请号：US809421
申请日：1997-04-28
申请人： Ryusuke Okamoto , Hideo Anraku
发明人： Ryusuke Okamoto , Hideo Anraku
IPC分类号： B01D17/02 , B01D21/00 , G01N33/48 , G01N33/49
CPC分类号： G01N33/491 , B01D17/0208 , B01D21/01 , G01N33/48 , B01D2221/10
摘要： The present invention relates to a serum or plasma separating composition comprising an oligomer of cyclopentadiene, an organic gelling agent and a dispersant for the organic gelling agent. The organic gelling agent is a condensation product of sorbitol and an aromatic aldehyde. The dispersant for the organic gelling agent is a polyoxyethylene-polyoxypropylene block copolymer having HLB of 1.0 to 9.0. The invention provides a serum or plasma separating composition which does not give out a bad smell by sterilization with radiation, has no influence derived from hemolysis, etc. on biochemical examination values of serum or plasma, does not cause phase separation of components, and is equal to the prior art in serum or plasma separating property, preservation stability, etc. Furthermore, the invention provides a serum or plasma separating composition which hardly brings about flow during preservation by standing in a horizontal lying position and hardly exhibits impaired invertibility with the lapse of time.
摘要翻译： PCT No.PCT / JP96 / 02390 Sec。 371日期1997年04月28日 102（e）1997年4月28日PCT PCT 1996年8月26日PCT公布。出版物WO97 / 08548 日本3月6日公开本发明涉及包含环戊二烯低聚物，有机胶凝剂和有机胶凝剂分散剂的血清或血浆分离组合物。有机胶凝剂是山梨糖醇与芳族醛的缩合产物。有机胶凝剂的分散剂是HLB为1.0〜9.0的聚氧乙烯 - 聚氧丙烯嵌段共聚物。本发明提供一种血清或血浆分离组合物，其通过放射线灭菌不会产生不良气味，对血清或血浆的生物化学检查值没有影响来自溶血等，不会引起组分的相分离，并且是等同于现有技术的血清或血浆分离性能，保存稳定性等。此外，本发明提供一种血清或血浆分离组合物，其通过在水平躺卧位置站立而几乎不会在保存期间产生流动，并且几乎不显示与经过的可逆性受损的时间。

7. 发明授权

US10182967B2 Plug and bodily fluid-collecting instrument set 有权
公开(公告)号：US10182967B2
公开(公告)日：2019-01-22
申请号：US13502479
申请日：2011-01-27
申请人： Masatoshi Niunoya , Ryusuke Okamoto
发明人： Masatoshi Niunoya , Ryusuke Okamoto
IPC分类号： A61B5/15 , B65D41/02 , A61J1/14 , B65D51/00 , A61B5/154 , A61J1/20
摘要： A plug that allows the plug body to be easily and reliably pierced through by a hollow bodily fluid collection needle, makes the bodily fluid collection needle difficult to draw back out of the plug body owing to a resilience of a sheath after the start of bodily fluid collection, and enables easy and reliable collection of the bodily fluid. The plug 1 is a plug for closing an opening end of a bodily fluid-collecting container 14 which is to be inserted into a tubular holder 11, and includes: a plug body 2 to be fixed to the opening end of the bodily fluid-collecting container 14; and a cover member 3 sheathed on the plug body 2 to cover an outer surface of the plug body 2, wherein the cover member 3 includes a side part 3c covering the outer surface of the plug body 2, and an outer surface of the side part 3c is provided with a protrusion 3k which protrudes radially outward of the side part 3c of the cover member 3 to come into contact with and give frictional resistance to an inner wall of the holder 11 upon insertion into the holder 11.

8. 发明授权

US08586323B2 Blood coagulation promoter and blood collection tube comprising a polyoxyalkylene glycerin derivative 有权
标题翻译：含有聚氧化烯甘油衍生物的凝血促进剂和采血管
公开(公告)号：US08586323B2
公开(公告)日：2013-11-19
申请号：US10548541
申请日：2004-04-21
申请人： Ryusuke Okamoto , Katsuya Togawa , Hironobu Isogawa
发明人： Ryusuke Okamoto , Katsuya Togawa , Hironobu Isogawa
IPC分类号： C12Q1/56 , G01N33/86
CPC分类号： C08L71/02 , A61B5/15003 , A61B5/150755 , A61B5/154 , B01L3/5082 , C08L2666/04
摘要： The present invention provides a blood coagulation promoter capable of exerting both excellent blood coagulation promoting ability and excellent blood clot detaching ability; and a blood collection tube accommodating the blood coagulation promoter.The present invention provides a blood coagulation promoter which includes a hardly water soluble polyoxyalkylene derivative; a partially saponificated polyvinyl alcohol; at least one substance selected from the group consisting of adsorptive inorganic substances and hydrolases capable of hydrolyzing a bond between Arg and an arbitrary amino acid reside and/or a bond between Lys and an arbitrary amino acid residue in a peptide chain; a polyvinylpyrrolidone; and preferably a water-soluble silicone oil, and a blood collection tube in which the blood coagulation promoter is accommodated in a tubular vessel having a bottom.
摘要翻译：本发明提供能够发挥优异的凝血促进能力和优异的血块分离能力的凝血促进剂; 以及容纳血液凝固促进剂的采血管。本发明提供一种凝血促进剂，其包含难溶于水的聚氧化烯衍生物; 部分皂化聚乙烯醇; 选自吸附性无机物质和能够水解Arg和任意氨基酸之间的键的水解物中的至少一种物质存在于肽链中Lys和任意氨基酸残基之间的和/或之间的键; 聚乙烯吡咯烷酮优选水溶性硅油，以及血液收集管，其中所述血液凝固促进剂容纳在具有底部的管状容器中。

9. 外观设计

USD688796S1 Cap for a blood collection tube 有权
标题翻译：盖上采血管
公开(公告)号：USD688796S1
公开(公告)日：2013-08-27
申请号：US29403130
申请日：2011-09-30
申请人： Masatoshi Niunoya , Ryusuke Okamoto
设计人： Masatoshi Niunoya , Ryusuke Okamoto

10. 发明授权

US09028688B2 Instrument for separating blood and apparatus for separating blood 有权
标题翻译：用于分离血液的仪器和用于分离血液的装置
公开(公告)号：US09028688B2
公开(公告)日：2015-05-12
申请号：US11994055
申请日：2006-06-26
申请人： Ryusuke Okamoto , Katsuya Togawa
发明人： Ryusuke Okamoto , Katsuya Togawa
IPC分类号： B01D29/00 , B01L3/00 , G01N33/49
CPC分类号： B01L3/5635 , B01L2300/0681 , G01N33/491
摘要： Blood separation material which separates blood collected in a blood-sampling container, into blood cells and plasma or serum within a short period of time. An apparatus for separating blood with the blood separation material. An instrument for separating blood having a first hollow needle extending toward one end, a second hollow needle extending toward the other end, a tubular container with an inner space in which the blood flows, and a blood separation material. A container with a first channel for supplying blood into an inner space through which blood flows from the needlepoint of the first hollow needle into the inner space, a second channel for blood to flow out from the inner space toward the needlepoint of the second hollow needle, and a third channel which allows air to flow from the outer space toward the needlepoint of the first hollow needle.
摘要翻译：将在血液取样容器中收集的血液在短时间内分离成血细胞和血浆或血清的血液分离材料。一种用血液分离材料分离血液的装置。一种用于分离具有朝向一端延伸的第一中空针的血液的仪器，朝向另一端延伸的第二空心针，具有血液流过的内部空间的管状容器和血液分离材料。一种具有第一通道的容器，用于将血液供应到内部空间中，血液从第一中空针的针尖流到内部空间，血液从内部空间朝向第二中空针的针尖流出的第二通道以及第三通道，其允许空气从外部空间朝向第一中空针的针尖流动。

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