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1. 发明授权

US06740662B1 Naphthyridine derivatives 失效
标题翻译：萘啶衍生物
公开(公告)号：US06740662B1
公开(公告)日：2004-05-25
申请号：US10111077
申请日：2002-04-19
申请人： Masahiro Iwata , Noriyuki Kawano , Tomofumi Takuwa , Ryota Shiraki , Miki Kobayashi , Makoto Takeuchi
发明人： Masahiro Iwata , Noriyuki Kawano , Tomofumi Takuwa , Ryota Shiraki , Miki Kobayashi , Makoto Takeuchi
IPC分类号： A61K31435
CPC分类号： C07D471/04 , A61K31/4375 , A61K31/439 , A61K31/444 , A61K31/4545 , A61K31/496 , A61K31/497 , A61K31/5377
摘要： 2-Oxo-1,2-dihydro-1,8-naphthyridine derivatives characterized by bearing a specific substituent, —X—R6, at the 3-position and a cyclic substituent, R5, at the 4-position; or salts thereof. The derivatives and the salts are useful as drugs, particularly preventive or therapeutic agents for respiratory diseases related to PDE IV.
摘要翻译： 2-氧代-1,2-二氢-1,8-二氮杂萘衍生物，其特征在于在3-位具有特定取代基-X-R 6，在4-位具有环取代基R 5; 或其盐。衍生物和盐可用作药物，特别是与PDE IV相关的呼吸道疾病的预防或治疗剂。

2. 发明授权

US07196080B2 Phenylpyridinecarbonylpiperazinederivative 失效
标题翻译：苯基吡啶羰基哌嗪基化
公开(公告)号：US07196080B2
公开(公告)日：2007-03-27
申请号：US10480543
申请日：2002-06-13
申请人： Masahiro Iwata , Noriyuki Kawano , Hiroyuki Kaizawa , Tomofumi Takuwa , Issei Tsukamoto , Ryushi Seo , Kiyoshi Yahiro , Miki Kobayashi , Makoto Takeuchi
发明人： Masahiro Iwata , Noriyuki Kawano , Hiroyuki Kaizawa , Tomofumi Takuwa , Issei Tsukamoto , Ryushi Seo , Kiyoshi Yahiro , Miki Kobayashi , Makoto Takeuchi
IPC分类号： A61K31/496 , C07D401/06 , C07D401/14 , C07D413/14 , C07D213/79
CPC分类号： C07D213/79 , A61K31/439 , A61K31/4418 , A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/4545 , A61K31/4709 , A61K31/4725 , A61K31/496 , A61K31/506 , A61K31/5355 , A61K31/5377 , A61K31/55 , C07D213/81 , C07D213/89 , C07D401/12 , C07D405/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D487/08
摘要： The present invention relates to a compound which is represented by the following general formula and has type 4 phosphodiesterase inhibitory action, and uses and an intermediate compound thereof. (wherein R1, R2: hydrogen, a halogen, a lower alkyl, a lower alkoxy, or the like, R3, R4: hydrogen, a (substituted) lower alkyl, a halogen, or the like, R5: hydrogen, a lower alkyl, a lower alkoxycarbonyl, or the like, and n: 0 or 1).
摘要翻译：本发明涉及由以下通式表示的具有4型磷酸二酯酶抑制作用的化合物及其用途及其中间体化合物。

3. 发明申请

US20110294749A1 DIAMINOPYRIMIDINECARBOXAMIDE DERIVATIVE 审中-公开
公开(公告)号：US20110294749A1
公开(公告)日：2011-12-01
申请号：US13171411
申请日：2011-06-28
申请人： Shinya Nagashima , Hiroshi Nagata , Masahiro Iwata , Masaki Yokota , Hiroyuki Moritomo , Eiichi Nakai , Sadao Kuromitsu , Keiko Ohga , Makoto Takeuchi
发明人： Shinya Nagashima , Hiroshi Nagata , Masahiro Iwata , Masaki Yokota , Hiroyuki Moritomo , Eiichi Nakai , Sadao Kuromitsu , Keiko Ohga , Makoto Takeuchi
IPC分类号： A61K31/505 , C07D413/12 , A61K31/5377 , C07D413/14 , C07D417/12 , A61K31/541 , C07H15/26 , A61K31/7064 , C07D403/12 , A61K31/551 , A61K31/553 , A61P11/06 , A61P11/00 , A61K31/506 , C07D239/48
CPC分类号： C07D403/12 , C07D239/48 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D417/12 , C07D451/04 , C07D453/02 , C07D471/10 , C07D487/08
摘要： A compound which may be used for the prevention or treatment of respiratory diseases in which STAT 6 is concerned, particularly asthma, chronic obstructive pulmonary disease and the like is provided.A pyrimidine derivative or a salt thereof, which has an arylamino or arylethylamino group which may be substituted with a specified substituent, at the 2-position, amino group substituted with benzyl group or the like, at the 4-position, and carbamoyl group which may be substituted, at the 5-position, is provided.
摘要翻译：提供了可用于预防或治疗其中涉及STAT6的呼吸系统疾病的化合物，特别是哮喘，慢性阻塞性肺病等。具有可以被特定取代基取代的芳基氨基或芳基乙氨基的嘧啶衍生物或其盐在2-位被苄基取代的4-氨基甲酰基和氨基甲酰基上，可以在5位被提供。

4. 发明授权

US07449456B2 Diaminopyrimidinecarboxamide derivative 有权
标题翻译：二氨基嘧啶甲酰胺衍生物
公开(公告)号：US07449456B2
公开(公告)日：2008-11-11
申请号：US10518043
申请日：2003-06-26
申请人： Shinya Nagashima , Hiroshi Nagata , Masahiro Iwata , Masaki Yokota , Hiroyuki Moritomo , Eiichi Nakai , Sadao Kuromitsu , Keiko Ohga , Makoto Takeuchi
发明人： Shinya Nagashima , Hiroshi Nagata , Masahiro Iwata , Masaki Yokota , Hiroyuki Moritomo , Eiichi Nakai , Sadao Kuromitsu , Keiko Ohga , Makoto Takeuchi
IPC分类号： C07D239/48 , A61K31/506
CPC分类号： C07D403/12 , C07D239/48 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D417/12 , C07D451/04 , C07D453/02 , C07D471/10 , C07D487/08
摘要： A compound which may be used for the prevention or treatment of respiratory diseases in which STAT 6 is concerned, particularly asthma, chronic obstructive pulmonary disease and the like is provided.A pyrimidine derivative or a salt thereof, which has an arylamino or arylethylamino group which may be substituted with a specified substituent, at the 2-position, amino group substituted with benzyl group or the like, at the 4-position, and carbamoyl group which may be substituted, at the 5-position, is provided.
摘要翻译：提供了可用于预防或治疗其中涉及STAT6的呼吸系统疾病的化合物，特别是哮喘，慢性阻塞性肺病等。具有可以被特定取代基取代的芳基氨基或芳基乙氨基的嘧啶衍生物或其盐在2-位被苄基取代的氨基或4-位上的氨基甲酰基和氨基甲酰基，可以在5位被提供。

5. 发明申请

US20050272753A1 Diaminopyrimidinecarboxa mide derivative 有权
标题翻译：二氨基嘧啶甲酰胺衍生物
公开(公告)号：US20050272753A1
公开(公告)日：2005-12-08
申请号：US10518043
申请日：2003-06-26
申请人： Shinya Nagashima , Hiroshi Nagata , Masahiro Iwata , Masaki Yokota , Hiroyuki Moritomo , Eiichi Nakai , Sadao Kuromitsu , Keiko Ohga , Makoto Takeuchi
发明人： Shinya Nagashima , Hiroshi Nagata , Masahiro Iwata , Masaki Yokota , Hiroyuki Moritomo , Eiichi Nakai , Sadao Kuromitsu , Keiko Ohga , Makoto Takeuchi
IPC分类号： A61P11/00 , A61P11/06 , A61P43/00 , C07D239/48 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D417/12 , C07D451/04 , C07D453/02 , C07D471/08 , C07D471/10 , C07D487/08 , A61K31/506 , A61K31/505 , C07D43/02
CPC分类号： C07D403/12 , C07D239/48 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D417/12 , C07D451/04 , C07D453/02 , C07D471/10 , C07D487/08
摘要： A compound which may be used for the prevention or treatment of respiratory diseases in which STAT 6 is concerned, particularly asthma, chronic obstructive pulmonary disease and the like is provided. A pyrimidine derivative or a salt thereof, which has an arylamino or arylethylamino group which may be substituted with a specified substituent, at the 2-position, amino group substituted with benzyl group or the like, at the 4-position, and carbamoyl group which may be substituted, at the 5-position, is provided.
摘要翻译：提供了可用于预防或治疗其中涉及STAT6的呼吸系统疾病的化合物，特别是哮喘，慢性阻塞性肺病等。具有可以被特定取代基取代的芳基氨基或芳基乙氨基的嘧啶衍生物或其盐在2-位被苄基取代的氨基或4-位上的氨基甲酰基和氨基甲酰基，可以在5位被提供。

6. 发明申请

US20110235848A1 FLAT ACOUSTIC TRANSDUCER AND METHOD FOR DRIVING THESAME 失效
标题翻译：平面振动传感器及其驱动方法
公开(公告)号：US20110235848A1
公开(公告)日：2011-09-29
申请号：US13133404
申请日：2009-11-30
申请人： Fumihito Meguro , Tomomi Nakatsuka , Masashi Hori , Hiromi Sotome , Masahiro Iwata , Kuniyuki Kobayashi
发明人： Fumihito Meguro , Tomomi Nakatsuka , Masashi Hori , Hiromi Sotome , Masahiro Iwata , Kuniyuki Kobayashi
IPC分类号： H04R9/06
CPC分类号： H04R7/045 , H04R2440/05
摘要： A flat acoustic transducer (100) includes a permanent magnet (10) and a magnetic member (20), which are arranged adjacent to each other with a predetermined interval, a flat vibrating membrane (30), provided facing the permanent magnet (10) and the magnetic member (20), and at least one coil (40), fixed to the vibrating membrane (30). In the flat acoustic transducer (100), an electrical signal is applied to the coil (40), to obtain vibration force (F) on the vibrating membrane (30) by way of a magnetic flux Φ generated between a magnetic pole face (12) of the permanent magnet (10) and the magnetic member (20), a step (50) is provided between the magnetic pole face (12) and the upper face (22) of the magnetic member (20), while at least part of a winding (42) of the coil (40) at the time of no application of an electrical signal is arranged inside the step (50).
摘要翻译：扁平的声学换能器（100）包括以预定的间隔彼此相邻布置的永磁体（10）和磁性构件（20），面向永磁体（10）设置的平坦的振动膜（30）和所述磁性部件（20）以及固定在所述振动膜（30）上的至少一个线圈（40）。在扁平声换能器（100）中，通过在磁极面（12）之间产生的磁通φ，向线圈（40）施加电信号，以获得振动膜（30）上的振动力（F））和所述磁性构件（20）之间，在所述磁极面（12）与所述磁性构件（20）的上表面（22）之间设置有台阶（50）在不施加电信号时线圈（40）的绕组（42）布置在台阶（50）的内部。

7. 发明授权

US08424066B2 Information processing apparatus, authentication system, information processing method and storage medium 有权
标题翻译：信息处理装置，认证系统，信息处理方法和存储介质
公开(公告)号：US08424066B2
公开(公告)日：2013-04-16
申请号：US12329652
申请日：2008-12-08
申请人： Kohshiro Inomata , Tadao Michimura , Hirochika Shionoiri , Masahiro Iwata
发明人： Kohshiro Inomata , Tadao Michimura , Hirochika Shionoiri , Masahiro Iwata
IPC分类号： G06F7/04
CPC分类号： H04L63/08 , G06F21/31
摘要： An information processing apparatus includes a storage unit that stores a first user identifier that identifies respective users in the information processing apparatus, and plural second user identifiers stored in respective authentication apparatuses and identify the users in each authentication apparatus, so as to correspond with each other; a first authentication request unit that transmits authentication information input by a user to at least one of the authentication apparatuses and requests authentication of the user; a first user identifier acquisition unit that, when authentication of the user has been successful, acquires the second user identifier of that user stored in that authentication apparatus; and a use allowing unit that specifies the first user identifier stored in the storage unit corresponding with the second user identifier acquired by the first user identifier acquisition unit, and allows the user identified by the specified first user identifier to use the information processing apparatus.
摘要翻译：一种信息处理装置，包括存储单元，其存储识别信息处理装置中的各个用户的第一用户标识符和存储在各认证装置中的多个第二用户标识符，并且识别每个认证装置中的用户，以便彼此对应 ; 第一认证请求单元，其将由用户输入的认证信息发送到所述认证装置中的至少一个，并请求所述用户的认证; 第一用户标识符获取单元，当用户的认证成功时，获取存储在该认证装置中的该用户的第二用户标识符; 以及使用允许单元，其指定存储在与由第一用户标识符获取单元获取的第二用户标识符相对应的存储单元中的第一用户标识符，并且允许由指定的第一用户标识符标识的用户使用信息处理设备。

8. 发明授权

US06755470B2 Seat reclining apparatus for automotive vehicle 失效
公开(公告)号：US06755470B2
公开(公告)日：2004-06-29
申请号：US10354976
申请日：2003-01-31
申请人： Masahiro Iwata , Atsushi Takano
发明人： Masahiro Iwata , Atsushi Takano
IPC分类号： B60N202
CPC分类号： B60N2/2252
摘要： A seat reclining apparatus for an automotive vehicle which employs a differential transmission mechanism in which an inner gear and an outer gear having slightly smaller number of teeth than the inner gear are supported in their partly engaged states by a rotation shaft part and an eccentric shaft which is eccentric with respect to the rotation shaft, wherein the eccentric shaft part includes two wedge plates sandwichingly inserted between a bearing ring inner peripheral surface of the outer gear and a bearing cylinder outer peripheral surface of the inner gear when the seatback is in the fixed position, a spring rod for biasing the two wedge plates in opposite peripheral directions, and an operation piece part for releasing the sandwichingly inserting states of the wedge plates when the seatback is in the fixed position by being rotated together with the rotation shaft and rotated together with the wedge plates when the seatback is in an adjusting position, each of the wedge plates being in a crescent shape including an arcuate outer surface part which is slid into contact with the inner peripheral surface of the bearing ring and an arcuate inner surface part which is slid into contact with the outer peripheral surface of the bearing cylinder when the seatback is in the adjusting position, and each of the wedge plates being approximately 180 degrees or more in arcuate angle which is formed between the arcuate outer surface part and the arcuate inner surface part, the two wedge plates being arranged in an overlapping relation in the axial direction of the rotation shaft.

9. 发明授权

US5817670A Naphthyridine derivatives and pharmaceutical compositions thereof 失效
标题翻译：萘啶衍生物及其药物组合物
公开(公告)号：US5817670A
公开(公告)日：1998-10-06
申请号：US776295
申请日：1997-01-30
申请人： Kazuhisa Takayama , Masahiro Iwata , Yoshinori Okamoto , Motonori Aoki , Akira Niwa , Yasuo Isomura
发明人： Kazuhisa Takayama , Masahiro Iwata , Yoshinori Okamoto , Motonori Aoki , Akira Niwa , Yasuo Isomura
IPC分类号： C07D471/04 , A61K31/435
CPC分类号： C07D471/04
摘要： 1,8-Naphthyridine derivatives represented by the following general formula (I), salts thereof, hydrates thereof and solvates thereof. ##STR1## They have an activity to inhibit type IV phosphodiesterase and are useful as agents for the prevention and treatment of respiratory diseases, inflammatory diseases accompanying organ transplantation, systemic or local arthropathy, proliferative diseases, micturition-related diseases and diseases in which tumor necrosis factor (TNF) and other cytokine (IL-1, IL-6 or the like) are concerned.
摘要翻译： PCT No.PCT / JP95 / 01700 Sec。 371日期1997年1月30日 102（e）日期1997年1月30日PCT 1995年8月28日PCT公布。公开号WO96 / 06843 日期：1993年3月7日，由以下通式（I）表示的8-萘啶衍生物，其盐，其水合物和溶剂化物。可用作预防和治疗呼吸系统疾病，伴随器官移植的炎性疾病，全身或局部关节病，增殖性疾病，排尿相关疾病和肿瘤坏死因子（TNF）等细胞因子（TNF-α） IL-1，IL-6等）。

10. 发明授权

US6136810A Pyrido[2,3-D]pyrimidine derivatives and pharmaceutical compositions thereof 失效
标题翻译：吡啶并[2,3-D]嘧啶衍生物及其药物组合物
公开(公告)号：US6136810A
公开(公告)日：2000-10-24
申请号：US66370
申请日：1998-04-30
申请人： Kazuhisa Takayama , Hiroyuki Hisamichi , Masahiro Iwata , Hideki Kubota , Motonori Aoki
发明人： Kazuhisa Takayama , Hiroyuki Hisamichi , Masahiro Iwata , Hideki Kubota , Motonori Aoki
IPC分类号： C07D471/04 , A61K31/505
CPC分类号： C07D471/04
摘要： This invention relates to compounds (I) or pharmaceutically acceptable salts thereof, having a function to inhibit type IV phosphodiesterase (PDE) ##STR1## [X: an oxygen atom or a sulfur atom, R.sup.1 : a lower alkyl group, a cycloalkyl-lower alkyl group or a cycloalkyl group,R.sup.2 : a hydrogen atom, a halogen atom, a lower alkyl group, a halogeno-lower alkyl group, a hydroxy-lower alkyl group, a mercapto-lower alkyl group, a lower alkoxy-lower alkyl group, a lower alkylthio-lower alkyl group, a lower alkanoyloxy-lower alkyl group, a lower alkanoylthio-lower alkyl group, a lower alkanoyl-lower alkyl group, a hydroxyimino-lower alkyl group, a lower alkoxyimino-lower alkyl group, a cycloalkyl group, an aryl group or a lower alkanoyl group,R.sup.3 : a hydrogen atom, a halogen atom or a lower alkyl group,R.sup.4 : a hydrogen atom or a lower alkyl group,R.sup.5 : a cycloalkyl group; a naphthyl group substituted; a five- or six-membered monocyclic hetero ring group having 1 to 4 hetero atoms selected from nitrogen atom, oxygen atom and sulfur atom; or a group represented by the formula ##STR2## amd F.sup.6 : a halogen atom, a lower alkyl group, a halogeno-lower alkyl group, a hydroxyl group, a lower alkoxy group, a cyano group or a nitro group].
摘要翻译： PCT No.PCT / JP96 / 03389。 371日期：1998年4月30日 102（e）1998年4月30日PCT PCT 1996年11月20日PCT公布。公开号WO97 / 19078 日期：1997年5月29日本发明涉及具有抑制IV型磷酸二酯酶（PDE）的功能的化合物（I）或其药学上可接受的盐[X：氧原子或硫原子，R 1：低级烷基，环烷基 - 低级烷基或环烷基，R2：氢原子，卤素原子，低级烷基，卤代低级烷基，羟基低级烷基，巯基低级烷基，低级烷氧基 - 低级烷基低级烷酰氧基 - 低级烷基，低级烷酰硫基 - 低级烷基，低级烷酰基 - 低级烷基，低级烷酰基 - 低级烷基，羟基亚氨基 - 低级烷基，低级烷氧基亚氨基 - 低级烷基，低级烷酰氧基 - 低级烷基环烷基，芳基或低级烷酰基，R3：氢原子，卤素原子或低级烷基，R4表示氢原子或低级烷基，R5表示环烷基。萘基取代; 具有1-4个选自氮原子，氧原子和硫原子的杂原子的五元或六元单环杂环基; 或由式amd F6表示的基团：卤素原子，低级烷基，卤代低级烷基，羟基，低级烷氧基，氰基或硝基]。

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