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    • 1. 发明授权
    • Device and method for observing reactions in samples
    • 用于观察样品反应的装置和方法
    • US07419836B2
    • 2008-09-02
    • US10760829
    • 2004-01-20
    • Markus SchuerfHarald GebetsroitherAndreas Erlbacher
    • Markus SchuerfHarald GebetsroitherAndreas Erlbacher
    • G01N21/00
    • G01N21/253G01N21/6452G01N21/76
    • The present invention relates to a device (1) for observing reactions in samples (2), to which a reagent (3) is added, and/or a method which is based on the use of this device. The device includes at least one first optical device (4) for observing samples (2) in the direction of a first optical axis (5) and in a first observation region (6) penetrated by the first optical axis; a first device (7) for receiving receptacles (8) containing samples (2) and for aligning samples in these receptacles in relation to the first optical axis (5); and an injection device (10) for adding liquids (3) to samples (2) and an illumination device (17) for irradiating the samples (2) with excitation light of a first wavelength. In this case, the injection device (10) is preferably positioned between the first optical device (4) and the receptacles (8) and includes at least one injector opening (11) of an injector needle (12) positioned in the observation region (6) of the first optical device (4) and a supply line (13) assigned thereto. The device (1) according to the present invention is characterized in that the injection device (10) for adding liquids (3) to samples (2) includes a tray (24) which is implemented for carrying and positioning the at least one injector needle (12) and its supply line (13).
    • 本发明涉及一种用于观察添加有试剂(3)的样品(2)中的反应的装置(1)和/或基于使用该装置的方法。 该装置包括至少一个第一光学装置(4),用于沿第一光轴(5)的方向观察样品(2)和在被第一光轴穿过的第一观察区域(6)中; 第一装置(7),用于接收容纳样品(2)的容器(8)并用于相对于所述第一光轴(5)将所述容器中的样品对准; 以及用于向样品(2)中加入液体(3)和用于用第一波长的激发光照射样品(2)的照明装置(17)的注射装置(10)。 在这种情况下,注射装置(10)优选地定位在第一光学装置(4)和容器(8)之间,并且包括位于观察区域(11)中的注射器针头(12)的至少一个注射器开口(11) 第一光学装置(4)的电源线(6)和分配给其的电源线(13)。 根据本发明的装置(1)的特征在于,用于向样品(2)添加液体(3)的注射装置(10)包括托盘(24),其被实施用于承载和定位至少一个注射针 (12)及其供应管线(13)。
    • 2. 发明授权
    • Laser scanner apparatus for fluorescence measurements
    • 激光扫描仪用于荧光测量
    • US08013313B2
    • 2011-09-06
    • US12853484
    • 2010-08-10
    • Andreas ErlbacherHarald GebetsroitherAndreas GfrorerGyoergy Wenczel
    • Andreas ErlbacherHarald GebetsroitherAndreas GfrorerGyoergy Wenczel
    • G01N21/64
    • G02B21/0076G02B5/04G02B26/105G02B27/141
    • Laser scanner and method images or measures fluorescent samples on specimen slides treated with different fluorescent dyes. Motor-driveable sample table for the slides includes a laser and first optical system creating two laser beams of differing wavelength, a scanner with movable head and an optical deflection element for deflecting the beams toward the sample. Scanner has second optical system for forwarding emission beam bundles to two detectors for detecting emission beam bundles coming from the samples. A drive and counter oscillator connected to the drive by connecting rods drives the head for rapid back-and-forth movement and the counter oscillator has a mass at least equivalent to the head for compensation by opposite movement to the head. The optical deflection element causes spatial separation of two resulting focal points and a spatial separation of the two beam bundles in the direction of the detectors.
    • 激光扫描仪和方法图像或测量用不同荧光染料处理的标本载玻片上的荧光样品。 用于滑块的电机可驱动样品台包括激光器和第一光学系统,其产生两个不同波长的激光束,具有可移动头的扫描仪和用于将光束偏转到样品的光学偏转元件。 扫描仪具有用于将发射束束转发到两个检测器的第二光学系统,用于检测来自样品的发射束束。 通过连杆连接到驱动器的驱动器和反相振荡器驱动头部用于快速的往复运动,并且反相振荡器具有至少相当于头部的质量,用于通过相对于头部的运动进行补偿。 光学偏转元件引起两个所产生的焦点的空间分离以及两个束束在检测器的方向上的空间分离。
    • 5. 发明授权
    • Device and method for analyzing samples
    • 用于分析样品的装置和方法
    • US07202945B2
    • 2007-04-10
    • US10878895
    • 2004-06-28
    • Andreas ErlbacherLutz NigglAlois Krutzenbichler
    • Andreas ErlbacherLutz NigglAlois Krutzenbichler
    • G01N21/03
    • G01N21/6452B01L3/5085B01L2300/0654B01L2300/0829B01L2300/168G01N21/0303G01N21/253G01N21/59G01N2021/6463G01N2021/6491G01N2021/651G01N2201/0446G01N2201/1042Y10S436/809
    • The present invention relates to a device (1) and a method for determining parameters of fluid-containing samples (2) in a system (3) for individually irradiating the samples (2) with light (4) of a light source (5) in an essentially vertical irradiation direction (6). In this case, this system (3) includes a detector (7) for measuring the light (8) coming from a single sample, and this detector (7) has a detection direction (9′), which lies on an optical axis (9) that is essentially parallel to the optical axis (6) of the light source (5). This device (1) includes at least one reflective surface (10), using which the light (4) coming essentially vertically out of the light source (5) may be at least partially deflected in an essentially horizontal irradiation direction (11). The device according to the present invention and the method according to the present invention are distinguished in that the detection direction (9′) of the detector (7)—for measuring the individual light (8) coming from a single sample (2)—is positioned at an angle to the optical axis of the light (4) irradiating the sample (2) in such a way that only the light (8) coming from the individual sample (2), but not this light (4), reaches the detector (7).
    • 本发明涉及一种用于在系统(3)中确定用于用光源(5)的光(4)单独照射样品(2)的系统(3)中的含液样品(2)的参数的装置(1)和方法, 在基本垂直的照射方向(6)上。 在这种情况下,该系统(3)包括用于测量来自单个样品的光(8)的检测器(7),并且该检测器(7)具有位于光轴(9')上的检测方向(9' 9),其基本上平行于光源(5)的光轴(6)。 该装置(1)包括至少一个反射表面(10),基本上垂直离开光源(5)的光线可以在基本上水平的照射方向(11)上至少部分地偏转。 根据本发明的装置和根据本发明的方法的特征在于,用于测量来自单个样品(2)的单个光(8)的检测器(7)的检测方向(9') - 被定位成与照射样品(2)的光(4)的光轴成一定角度,使得仅来自各个样品(2)的光(8)而不是该光(4)到达 检测器(7)。
    • 6. 发明授权
    • Apparatus for emitting pulses of light and systems employing such apparatus
    • 用于发射光脉冲的装置和采用这种装置的系统
    • US07088054B2
    • 2006-08-08
    • US10833226
    • 2004-04-27
    • Andreas ErlbacherWolfgang FuchsLutz Niggl
    • Andreas ErlbacherWolfgang FuchsLutz Niggl
    • H05B41/30
    • H05B41/30
    • An apparatus with a flash lamp can trigger a flash of light by application of an ignition pulse. The apparatus encompasses a first capacitor, a second capacitor, a switching element and a control circuit. The first capacitor, second capacitor and switching element are arranged in a network in such a way that the switching element is located on the low side of a power circuit. The apparatus can be operated in a first mode and a second mode by actuating the control circuit. In the first mode the first capacitor is discharged by the flash lamp, triggering a flash of light of high energy. In the second mode the second capacitor is discharged by the flash lamp and a flash of light of low energy is triggered.
    • 具有闪光灯的装置可以通过施加点火脉冲来触发闪光。 该装置包括第一电容器,第二电容器,开关元件和控制电路。 第一电容器,第二电容器和开关元件布置在网络中,使得开关元件位于电源电路的低侧。 该装置可以通过启动控制电路在第一模式和第二模式下操作。 在第一模式中,第一电容器被闪光灯放电,触发高能量的闪光。 在第二模式中,第二电容器被闪光灯放电,并且触发低能量的闪光。
    • 7. 发明申请
    • Device and method for analyzing samples
    • 用于分析样品的装置和方法
    • US20050030541A1
    • 2005-02-10
    • US10878895
    • 2004-06-28
    • Andreas ErlbacherLutz NigglAlois Krutzenbichler
    • Andreas ErlbacherLutz NigglAlois Krutzenbichler
    • B01L3/00G01N21/03G01N21/25G01N21/53G01N21/59G01N21/64G01N21/65G02F1/03G01N21/00G02F1/07
    • G01N21/6452B01L3/5085B01L2300/0654B01L2300/0829B01L2300/168G01N21/0303G01N21/253G01N21/59G01N2021/6463G01N2021/6491G01N2021/651G01N2201/0446G01N2201/1042Y10S436/809
    • The present invention relates to a device (1) and a method for determining parameters of fluid-containing samples (2) in a system (3) for individually irradiating the samples (2) with light (4) of a light source (5) in an essentially vertical irradiation direction (6). In this case, this system (3) includes a detector (7) for measuring the light (8) coming from a single sample, and this detector (7) has a detection direction (9′), which lies on an optical axis (9) that is essentially parallel to the optical axis (6) of the light source (5). This device (1) includes at least one reflective surface (10), using which the light (4) coming essentially vertically out of the light source (5) may be at least partially deflected in an essentially horizontal irradiation direction (11). The device according to the present invention and the method according to the present invention are distinguished in that the detection direction (9′) of the detector (7)—for measuring the individual light (8) coming from a single sample (2)—is positioned at an angle to the optical axis of the light (4) irradiating the sample (2) in such a way that only the light (8) coming from the individual sample (2), but not this light (4), reaches the detector (7).
    • 本发明涉及一种用于在系统(3)中确定用于用光源(5)的光(4)单独照射样品(2)的系统(3)中的含液样品(2)的参数的装置(1)和方法, 在基本垂直的照射方向(6)上。 在这种情况下,该系统(3)包括用于测量来自单个样品的光(8)的检测器(7),并且该检测器(7)具有位于光轴(9')上的检测方向(9' 9),其基本上平行于光源(5)的光轴(6)。 该装置(1)包括至少一个反射表面(10),基本上垂直离开光源(5)的光线可以在基本上水平的照射方向(11)上至少部分地偏转。 根据本发明的装置和根据本发明的方法的特征在于,用于测量来自单个样品(2)的单个光(8)的检测器(7)的检测方向(9') - 被定位成与照射样品(2)的光(4)的光轴成一定角度,使得仅来自各个样品(2)的光(8)而不是该光(4)到达 检测器(7)。