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1. 发明申请

US20100160747A1 SELECTION OF PREFERRED SAMPLING LOCATION ON HAND VIA MINIMIZATION OF SAMPLING ERROR, AND OPTICAL ALIGNMENT FOR REPEATABLY SAMPLING TISSUE 审中-公开
标题翻译：选择采样误差最小化时的优选采样位置，以及可重复采样组织的光学对准
公开(公告)号：US20100160747A1
公开(公告)日：2010-06-24
申请号：US12636771
申请日：2009-12-13
申请人： Mark Ries Robinson , Andrea Magee , Michael J. Haass , Russell E. Abbink , William Radigan , V. Gerald Grafe
发明人： Mark Ries Robinson , Andrea Magee , Michael J. Haass , Russell E. Abbink , William Radigan , V. Gerald Grafe
IPC分类号： A61B5/1468 , A61B5/00
CPC分类号： A61B5/061 , A61B5/0059 , A61B5/14532 , A61B5/442 , A61B5/444
摘要： The present invention relates to measurements of material properties by determination of the response of a sample to incident radiation, and more specifically to the measurement of analytes such as glucose or alcohol in human tissue. The invention is particularly useful in connection with noncontact optical sampling of skin. Some example embodiments of the invention provide for selection of preferred sampling locations responsive to optically-determined characteristics of the tissue. Some example embodiments of the invention provide for precise and repeatable alignment of the tissue based on optically-determined characteristics of the tissue.
摘要翻译：本发明涉及通过测定样品对入射辐射的响应，更具体地涉及人体组织中分析物如葡萄糖或酒精的测量来测量材料性质。本发明特别适用于皮肤的非接触光学取样。本发明的一些示例性实施例提供了响应于光学确定的组织特征的优选采样位置的选择。本发明的一些示例性实施例提供了基于光学确定的组织特征的组织的精确和可重复的对准。

2. 发明申请

US20100113899A1 Alignment System for Optically Sampling a Hand 审中-公开
标题翻译：用于光学取样的对准系统
公开(公告)号：US20100113899A1
公开(公告)日：2010-05-06
申请号：US12614056
申请日：2009-11-06
申请人： Mark Ries Robinson , Andrea Magee , Michael U. Haass , Russell E. Abbink , William Radigan , V. Gerald Grafe
发明人： Mark Ries Robinson , Andrea Magee , Michael U. Haass , Russell E. Abbink , William Radigan , V. Gerald Grafe
IPC分类号： A61B5/1455
CPC分类号： A61B5/1455 , A61B5/14532 , A61B5/6825 , A61B5/6826 , A61B5/6838
摘要： This invention relates to measurements of material properties by determination of the response of a sample to incident radiation, and more specifically to the measurement of analytes such as glucose or alcohol in human tissue. Some example embodiments of the present invention provide an optical sampling apparatus including an optical subsystem, having a receiver for receiving light expressed from tissue; and an alignment subsystem, adapted to urge a portion of a hand placed in operative relationship with the alignment subsystem into a defined configuration relative to the receiver. In some such example embodiments, the alignment subsystem includes a substrate having a plurality of projections therefrom disposed in a pattern such that the projections urge a portion of a hand placed on the substrate to a defined configuration relative to the receiver. In some such example embodiments, the alignment subsystem includes a substrate having a surface defining a volume approximating the shape of a portion of a hand such that the volume urges a portion of a hand placed therein to a defined configuration relative to the receiver. In some such example embodiments, the alignment subsystem includes a surface having a generally U-shaped cross-section and extending for a distance, wherein the surface is mounted relative to the sampling means such that a finger placed in the U-shaped cross-section of the surface is urged to a defined configuration relative to the receiver. In some such sample embodiments, the alignment subsystem is customized to portion of the hand of a specific individual.
摘要翻译：本发明涉及通过测定样品对入射辐射的响应，更确切地说，涉及人体组织中分析物如葡萄糖或醇的测量来测量材料性质。本发明的一些示例性实施例提供一种包括光学子系统的光采样装置，其具有用于接收从组织表达的光的接收器; 以及对准子系统，其适于将与所述对准子系统处于可操作关系的手的一部分相对于所述接收器推定为限定的配置。在一些这样的示例性实施例中，对准子系统包括具有多个突起的衬底，该突出部设置成图案，使得突起将放置在衬底上的手的一部分相对于接收器推压到限定的构型。在一些这样的示例性实施例中，对准子系统包括具有限定近似手部的形状的体积的表面的衬底，使得该体积将其中放置的手的一部分相对于接收器施加到限定的构型。在一些这样的示例性实施例中，对准子系统包括具有大致U形横截面并延伸一定距离的表面，其中相对于采样装置安装表面，使得手指放置在U形横截面的表面被推动到相对于接收器的限定的配置。在一些这样的示例性实施例中，对准子系统被定制为特定个体的手的部分。

3. 发明申请

US20090048576A1 Managing Cross-contamination in Blood Samples Withdrawn from a Multilumen Catheter 审中-公开
标题翻译：管理从多次导管撤回的血液样本中的交叉污染
公开(公告)号：US20090048576A1
公开(公告)日：2009-02-19
申请号：US11860544
申请日：2007-09-25
申请人： Mark Ries Robinson , Mike Borrello , John O'Mahony , Richard Thompson , Dave Tobler , V. Gerald Grafe
发明人： Mark Ries Robinson , Mike Borrello , John O'Mahony , Richard Thompson , Dave Tobler , V. Gerald Grafe
IPC分类号： A61M25/01
CPC分类号： A61B5/150961 , A61B5/14532 , A61B5/15003 , A61B5/150213 , A61B5/150221 , A61B5/150229 , A61B5/155 , A61B5/157
摘要： The present invention comprises methods and apparatuses that can provide accurate measurement of glucose or other analytes from a multilumen catheter in the presence of infusion of substances, including glucose. Examples of “multilumen catheters” include central venous catheters having multiple lumens, midline catheters having multiple lumens, multiple catheters configured or emplaced such that their lumens are in proximity to each other, and, in the case of indwelling analyte sensors, a catheter with a lumen for infusion and an indwelling sensor spaced apart from the infusion lumen. For blood withdrawal, anti-cross contamination controls can prevent the entrainment of blood which might be contaminated with feeding fluids or medications that are administered through other lumens within the catheter and in proximity of the blood sampling port. Cross contamination can occur under various situations, and is known to occur when the patient is connected to a ventilator. The ventilator cyclically raises the intra-thoracic pressure and diminishes blood flow rate in the central veins returning to the heart. The diminished flow can increase the chances for cross-contamination when additional lumens are introducing fluids during a draw sample.
摘要翻译：本发明包括在存在输入物质（包括葡萄糖）的情况下可以提供来自多腔导管的葡萄糖或其它分析物的精确测量的方法和装置。 “多腔导管”的实例包括具有多个腔的中心静脉导管，具有多个腔的中线导管，配置或放置多个导管，使得它们的内腔彼此靠近，并且在留置分析物传感器的情况下，用于输注的内腔和与输液腔间隔开的留置传感器。为了取血，反交叉污染控制可以防止可能被导管内和在血液采样端口附近通过其他管腔给药液体或药物而被污染的血液夹带。交叉污染可以在各种情况下发生，并且已知当患者连接到通气机时发生交叉污染。呼吸机周期性地升高胸腔内压，并减少返回心脏的中央静脉血流量。减少的流量可以增加在抽取样品期间附加管腔引入流体时交叉污染的机会。

4. 发明申请

US20090048535A1 Detecting Cross-contamination in Blood Measurements with a Multilumen Catheter 审中-公开
标题翻译：用多次导管检测血液测量中的交叉污染
公开(公告)号：US20090048535A1
公开(公告)日：2009-02-19
申请号：US11860545
申请日：2007-09-25
申请人： Mark Ries Robinson , Mike Borrello , John O'Mahony , Richard Thompson , V. Gerald Grafe
发明人： Mark Ries Robinson , Mike Borrello , John O'Mahony , Richard Thompson , V. Gerald Grafe
IPC分类号： A61B5/155
CPC分类号： A61B5/150961 , A61B5/14532 , A61B5/15003 , A61B5/150213 , A61B5/150221 , A61B5/150229 , A61B5/155 , A61B5/157
摘要： The present invention comprises methods and apparatuses that can provide accurate measurement of glucose or other analytes from a multilumen catheter in the presence of infusion of substances, including glucose. Examples of “multilumen catheters” include central venous catheters having multiple lumens, midline catheters having multiple lumens, multiple catheters configured or emplaced such that their lumens are in proximity to each other, and, in the case of indwelling analyte sensors, a catheter with a lumen for infusion and an indwelling sensor spaced apart from the infusion lumen. For blood withdrawal, anti-cross contamination controls can prevent the entrainment of blood which might be contaminated with feeding fluids or medications that are administered through other lumens within the catheter and in proximity of the blood sampling port. Cross contamination can occur under various situations, and is known to occur when the patient is connected to a ventilator. The ventilator cyclically raises the intra-thoracic pressure and diminishes blood flow rate in the central veins returning to the heart. The diminished flow can increase the chances for cross-contamination when additional lumens are introducing fluids during a draw sample.
摘要翻译：本发明包括在存在输入物质（包括葡萄糖）的情况下可以提供来自多腔导管的葡萄糖或其它分析物的精确测量的方法和装置。 “多腔导管”的实例包括具有多个内腔的中心静脉导管，具有多个腔的中线导管，多个导管被配置或放置成使得它们的内腔彼此靠近，并且在留置分析物传感器的情况下，用于输注的内腔和与输液腔间隔开的留置传感器。为了取血，反交叉污染控制可以防止可能被导管内和在血液采样端口附近通过其他管腔给药液体或药物而被污染的血液夹带。交叉污染可以在各种情况下发生，并且已知当患者连接到通气机时发生交叉污染。呼吸机周期性地升高胸腔内压，并减少返回心脏的中央静脉血流量。减少的流量可以增加在抽取样品期间附加管腔引入流体时交叉污染的机会。

5. 发明授权

US5769154A Heat pipe with embedded wick structure 失效
公开(公告)号：US5769154A
公开(公告)日：1998-06-23
申请号：US593596
申请日：1996-01-29
申请人： Douglas Ray Adkins , David S. Shen , Melanie R. Tuck , David W. Palmer , V. Gerald Grafe
发明人： Douglas Ray Adkins , David S. Shen , Melanie R. Tuck , David W. Palmer , V. Gerald Grafe
IPC分类号： F28D15/02 , F28D15/04 , F28D15/00
CPC分类号： F28D15/04 , F28D15/0233 , F28D15/046
摘要： A heat pipe has an embedded wick structure that maximizes capillary pumping capability. Heat from attached devices such as integrated circuits evaporates working fluid in the heat pipe. The vapor cools and condenses on a heat dissipation surface. The condensate collects in the wick structure, where capillary pumping returns the fluid to high heat areas.

6. 发明申请

US20090201247A1 Communications with a Haptic Interface Device from a Host Computer 有权
标题翻译：与主机的触觉接口设备的通信
公开(公告)号：US20090201247A1
公开(公告)日：2009-08-13
申请号：US12363720
申请日：2009-01-31
申请人： Walter A. Aviles , Thomas G. Anderson , V. Gerald Grafe
发明人： Walter A. Aviles , Thomas G. Anderson , V. Gerald Grafe
IPC分类号： G09G5/00
CPC分类号： G06F3/016 , G06F3/038
摘要： The present invention comprises methods and apparatuses that can provide reliable communications between a computer and a haptic interface device. The methods and apparatuses can provide communication that is more secure against errors, failures, or tampering than previous approaches. Haptic devices allow a user to communicate with computer applications using the user's sense of touch, for example by applying and sensing forces with the haptic device. The host computer must be able to communicate with the haptic device in a robust and safe manner. The present invention includes a novel method of accomplishing such communication; a computer-readable medium that, when applied to a computer, causes the computer to communicate according to such a method; and a computer system having a host computer and a haptic device communicating according to such a method.
摘要翻译：本发明包括可以在计算机和触觉界面装置之间提供可靠通信的方法和装置。这些方法和装置可以提供比以前的方法更可靠地防止错误，故障或篡改的通信。触觉设备允许用户使用用户的触摸感觉与计算机应用程序进行通信，例如通过应用和感测与触觉设备的力。主机必须能够以稳健和安全的方式与触觉设备进行通信。本发明包括实现这种通信的新方法; 计算机可读介质，当应用于计算机时，使计算机根据这种方法进行通信; 以及具有根据这种方法通信的主计算机和触觉装置的计算机系统。

7. 发明授权

US09804672B2 Human-computer user interaction 有权
公开(公告)号：US09804672B2
公开(公告)日：2017-10-31
申请号：US12783386
申请日：2010-05-19
申请人： Thomas G. Anderson , Bill Anderson , Walter Aviles , Richard Aviles , Jake Jones , V. Gerald Grafe
发明人： Thomas G. Anderson , Bill Anderson , Walter Aviles , Richard Aviles , Jake Jones , V. Gerald Grafe
IPC分类号： G06F3/038 , G06F3/0481 , G06F3/0482 , G06F3/0483 , G06F3/01
CPC分类号： G06F3/016 , G06F3/017
摘要： Methods of and apparatuses for providing human interaction with a computer, including human control of three dimensional input devices, force feedback, and force input.

8. 发明授权

US06389418B1 Patent data mining method and apparatus 有权
标题翻译：专利数据挖掘方法和装置
公开(公告)号：US06389418B1
公开(公告)日：2002-05-14
申请号：US09500729
申请日：2000-02-09
申请人： Kevin W. Boyack , V. Gerald Grafe , David K. Johnson , Brian N. Wylie
发明人： Kevin W. Boyack , V. Gerald Grafe , David K. Johnson , Brian N. Wylie
IPC分类号： G06F1730
CPC分类号： G06F17/30716 , G06F17/30722 , G06F2216/03 , Y10S707/99936 , Y10S707/99943
摘要： A method of data mining represents related patents in a multidimensional space. Distance between patents in the multidimensional space corresponds to the extent of relationship between the patents. The relationship between pairings of patents can be expressed based on weighted combinations of several predicates. The user can select portions of the space to perceive. The user also can interact with and control the communication of the space, focusing attention on aspects of the space of most interest. The multidimensional spatial representation allows more ready comprehension of the structure of the relationships among the patents.
摘要翻译：数据挖掘的方法代表了多维空间中的相关专利。多维空间专利之间的距离对应于专利之间的关系程度。专利配对之间的关系可以基于几个谓词的加权组合来表示。用户可以选择要感知的空间的部分。用户还可以与空间的通信进行交互和控制，将注意力集中在最感兴趣的空间方面。多维空间表示可以更准确地理解专利之间关系的结构。

9. 发明申请

US20130145240A1 Customizable System for Storytelling 审中-公开
标题翻译：可定制的讲故事制度
公开(公告)号：US20130145240A1
公开(公告)日：2013-06-06
申请号：US13705159
申请日：2012-12-04
申请人： Thomas G. Anderson , Bill Anderson , V. Gerald Grafe
发明人： Thomas G. Anderson , Bill Anderson , V. Gerald Grafe
IPC分类号： G06F3/0483
CPC分类号： G06F3/0483 , G09B5/062
摘要： A system for creating customizable books or other applications is described, along with techniques and methods for implementing customizable features in the books or applications.
摘要翻译：描述了用于创建可定制书籍或其他应用程序的系统，以及用于在书籍或应用程序中实现可定制功能的技术和方法。

10. 发明申请

US20120143101A1 HIP ACTUATOR THAT FACILITATES RECOVERY FROM SURGERY 审中-公开
标题翻译：手术恢复手术的HIP执行器
公开(公告)号：US20120143101A1
公开(公告)日：2012-06-07
申请号：US13304607
申请日：2011-11-25
申请人： Paul B. Schmidt , V. Gerald Grafe
发明人： Paul B. Schmidt , V. Gerald Grafe
IPC分类号： A61H1/02
CPC分类号： A61H1/0244 , A61H2201/0157 , A61H2201/0176 , A61H2201/0184 , A61H2201/0192 , A61H2201/1215 , A61H2201/149 , A61H2201/164 , A61H2201/1642 , A61H2201/1664 , A61H2201/1671 , A61H2201/5007 , A61H2201/5038 , A61H2201/5058 , A61H2201/5097 , A63B21/4015 , A63B21/4033 , A63B21/4049 , A63B23/0405 , A63B23/0482
摘要： The present invention provides methods and apparatuses that can facilitate recovery from various kinds of hip surgery. Example embodiments comprise a foot motion subsystem and a knee restraint, wherein a patient's foot engaged with the foot holder is moved and the patient's knee is restrained such that motion of the foot is transmitted to the patient's hip.
摘要翻译：本发明提供了可以促进从各种髋部手术恢复的方法和装置。示例性实施例包括脚部运动子系统和膝盖约束，其中与脚架接合的患者脚部被移动并且患者的膝盖受到限制，使得脚部的运动被传递到患者的臀部。

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