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1. 发明申请

US20080038163A1 Systems and Methods for Cooling in Biological Analysis Instruments 审中-公开
标题翻译：生物分析仪器冷却系统和方法
公开(公告)号：US20080038163A1
公开(公告)日：2008-02-14
申请号：US11757286
申请日：2007-06-01
申请人： Steven Boege , John Sheridan , Ali Aslam , Dennis Lehto , Julio Focaracci , Alexander Dromaretsky , Thomas Au , Mark Oldham , Eric Henderson , Vinod Mirchandani , Eric Nordman , Marc Haberstroh , Johannes Sluis
发明人： Steven Boege , John Sheridan , Ali Aslam , Dennis Lehto , Julio Focaracci , Alexander Dromaretsky , Thomas Au , Mark Oldham , Eric Henderson , Vinod Mirchandani , Eric Nordman , Marc Haberstroh , Johannes Sluis
IPC分类号： F28F99/00 , B01J19/00
CPC分类号： B01L7/52 , B01L2300/0636 , B01L2300/0829 , B01L2300/0877 , B01L2300/1822 , B01L2300/1844 , B01L2300/185
摘要： A device for performing biological analysis may include at least one reaction chamber configured to receive at least one sample for biological analysis and a thermal system configured to modulate a temperature of the at least one reaction chamber to cycle a temperature of the at least one biological sample. The thermal system may include a cooling system configured to cool the at least one reaction chamber. The cooling system may include a cooling fluid source positioned distally from the at least one reaction chamber, the cooling fluid source being in flow communication with at least one conduit configured to flow cooling fluid from the cooling fluid source to at least one location in thermal communication with the at least one reaction chamber.
摘要翻译：用于进行生物分析的装置可以包括至少一个反应室，其配置成容纳至少一个用于生物分析的样品，以及被配置为调节至少一个反应室的温度以循环至少一个生物样品的温度的热系统。热系统可以包括被配置为冷却至少一个反应室的冷却系统。所述冷却系统可以包括从所述至少一个反应室向远侧定位的冷却流体源，所述冷却流体源与至少一个管道流动连通，所述至少一个导管构造成将来自所述冷却流体源的冷却流体流动到热通信中的至少一个位置与至少一个反应室。

2. 发明申请

US20080050781A1 Systems and Methods for Cooling in a Thermal Cycler 审中-公开
标题翻译：热循环器冷却系统和方法
公开(公告)号：US20080050781A1
公开(公告)日：2008-02-28
申请号：US11767327
申请日：2007-06-22
申请人： Mark Oldham , Eric Henderson , Vinod Mirchandani , Eric Nordman , Marc Haberstroh , Johannes Sluis
发明人： Mark Oldham , Eric Henderson , Vinod Mirchandani , Eric Nordman , Marc Haberstroh , Johannes Sluis
IPC分类号： C12P19/34 , B01J19/00 , C12M1/38
CPC分类号： B01L7/52 , B01L2300/0636 , B01L2300/0829 , B01L2300/0877 , B01L2300/1822 , B01L2300/1844 , B01L2300/185
摘要： A device for performing polymerase chain reactions using cooling members not used in conventional thermal cyclers. A device for performing polymerase chain reactions may include a sample holder configured to receive a nucleic acid sample, a heating system configured to raise the temperature of the sample, a cooling system configured to lower the temperature of the sample, and a controller configured to operably control the heating system and the cooling system to cycle the device through a desired time-temperature profile. The cooling system may comprise at least one cooling member selected from a synthetic jet ejector array, a vibration-induced droplet atomization system, a vibrating diaphragm system, a piezo fan, a Cold Gun, a microchannel cooling loop, and a Cool Chip.
摘要翻译：使用不用于常规热循环仪的冷却部件进行聚合酶链反应的装置。用于进行聚合酶链式反应的装置可以包括配置成接收核酸样品的样品架，配置成提高样品温度的加热系统，配置成降低样品温度的冷却系统，以及配置成可操作地控制加热系统和冷却系统以使设备循环所需的时间 - 温度曲线。冷却系统可以包括选自合成射流喷射器阵列，振动诱导液滴雾化系统，振动膜系统，压电风扇，冷枪，微通道冷却回路和冷却芯片中的至少一个冷却构件。

3. 发明申请

US20070194495A1 Method for producing a detachably connected container having barrier properties 有权
标题翻译：用于制造具有阻隔性的可拆卸连接的容器的方法
公开(公告)号：US20070194495A1
公开(公告)日：2007-08-23
申请号：US11358567
申请日：2006-02-20
申请人： Eric Henderson , John Michels
发明人： Eric Henderson , John Michels
IPC分类号： B29C43/02
CPC分类号： B29C43/02 , B29C33/0022 , B29C37/0057 , B29C51/082 , B29C51/10 , B29C2043/023 , B29C2793/0045 , B29K2023/065 , B29K2023/086 , B29K2023/12 , B29K2025/00 , B29K2995/0067 , B29L2031/22 , B65D1/30
摘要： A method is provided of forming a multi-pack container assembly having at least two containers joined together by a channel. The method includes the steps of providing sheet having a barrier layer thermoforming the sheet into a multi-pack container assembly having a plurality of containers wherein each container comprises a flange and the flanges of adjacent containers are connected by an engineered area of weakness or channel. Resultant containers can be used for low-moisture, shelf-stable, ready-to-eat food products.
摘要翻译：提供一种形成具有通过通道连接在一起的至少两个容器的多包装容器组件的方法。该方法包括以下步骤：提供具有将片材热成型为具有多个容器的多包装容器组件的阻挡层的片材，其中每个容器包括凸缘，并且相邻容器的凸缘通过设计的弱点或通道区域连接。所得容器可用于低水分，货架稳定的即食食品。

4. 发明申请

US20050266149A1 Method and apparatus for depositing material onto a surface 失效
标题翻译：用于将材料沉积到表面上的方法和设备
公开(公告)号：US20050266149A1
公开(公告)日：2005-12-01
申请号：US11120042
申请日：2005-04-29
申请人： Eric Henderson , Juntao Xu , Michael Lynch , Curtis Mosher , Janice Huff , Saju Nettikadan
发明人： Eric Henderson , Juntao Xu , Michael Lynch , Curtis Mosher , Janice Huff , Saju Nettikadan
IPC分类号： A61L2/00 , B01L3/02 , B05B7/06 , B05C1/00 , B05D3/00
CPC分类号： B01L3/0244 , B01J2219/00387 , B01J2219/00659 , B01L3/0248 , B01L2200/12 , B01L2200/143 , B01L2300/0816 , B01L2300/0838 , B01L2300/10 , B01L2400/02 , B01L2400/0406
摘要： Some embodiments of the present invention provide an apparatus and method in which material is deposited upon a surface from an elongated beam having an aperture defined therein through which the material is moved by passive adsorption. The elongated beam can be substantially planar along substantially its entire length, can be oriented at an acute angle with respect to the surface during deposition processes, and can have a length no greater than about 2 mm. In some embodiments, the aperture can be elongated, can extend from a material reservoir to a location short of the terminal end of the elongated beam or through the terminal end of the elongated beam, and can have a portion extending through the thickness of the elongated beam.
摘要翻译：本发明的一些实施例提供了一种装置和方法，其中材料从具有限定在其中的孔的细长梁沉积在表面上，通过该孔通过被动吸附来移动材料。细长梁基本上可以在其整个长度上基本上是平面的，可以在沉积过程中相对于表面以锐角定向，并且可以具有不大于约2mm的长度。在一些实施例中，孔可以是细长的，可以从材料储存器延伸到短于细长梁的终端的位置或者通过细长梁的终端，并且可以具有延伸穿过细长梁的厚度的部分光束。

5. 发明申请

US20050238766A1 Bandolier format packaging 有权
标题翻译： Bandolier格式包装
公开(公告)号：US20050238766A1
公开(公告)日：2005-10-27
申请号：US11103770
申请日：2005-04-12
申请人： Eric Henderson , Garrett Kohl , Steven Tucker
发明人： Eric Henderson , Garrett Kohl , Steven Tucker
IPC分类号： B65B9/20 , B65B61/00 , C12C1/027
CPC分类号： B26F1/14 , B26F1/44 , B26F2001/4472 , B26F2001/4481 , B29C65/18 , B29C65/7457 , B29C66/112 , B29C66/1122 , B29C66/135 , B29C66/4312 , B29C66/4322 , B29C66/49 , B29C66/71 , B29C66/72321 , B29C66/7234 , B29C66/73711 , B29C66/73713 , B29C66/81427 , B29C66/8322 , B29C66/83221 , B29C66/849 , B29C2793/0045 , B29C2795/002 , B65B9/2042 , B65B9/207 , B65B9/213 , B65B9/22 , B65B61/007 , B65B2220/18 , B65B2220/22 , B65D75/008 , B29K2023/12 , B29K2067/00 , B29K2023/00 , B29K2023/065 , B29K2067/003 , B29K2023/0633 , B29K2023/06
摘要： A product and method for producing a string of individual sealed, filled packages separated by perforations. A string of separate packages optionally may be enclosed in a cardboard or other container designed to sit in a pantry or other location for dispensing of individual units. Perforations in the packaging film between separate packages provide a tear point to aid in separating one package from the next. There are several advantages to this format including easy placement of the string of packages into a carton for shipping or dispensing, and the ability to hang a string of packages in locations without the need to attach the packages to a backing strip. The perforations between packages facilitate the packaging and transportation of the entire string or bandolier, and facilitate the removal and use of a separate package.
摘要翻译：用于生产由穿孔分开的单个密封填充包装的串的产品和方法。一串独立的包装可选择地封闭在纸板或其他容器中，设计用于坐在厨房或其他位置以分配单独的单元。单独包装之间的包装膜中的穿孔提供了一个撕裂点，以帮助将一个包装与下一个包装分开。这种格式有几个优点，包括将包装串容易地放置到用于运输或分发的纸箱中，以及将一串包装挂在位置的能力，而不需要将包装附接到背衬条上。包装之间的穿孔有助于包装和运输整个绳索或皮带轮，并且便于拆卸和使用单独的包装。

6. 发明授权

US5935339A Decontamination device and method thereof 失效
标题翻译：去污装置及其方法
公开(公告)号：US5935339A
公开(公告)日：1999-08-10
申请号：US766871
申请日：1996-12-13
申请人： Eric Henderson , James Vesenka
发明人： Eric Henderson , James Vesenka
IPC分类号： B01J19/08 , B08B7/00
CPC分类号： G01Q30/20 , B08B7/0035 , B82Y35/00
摘要： One embodiment of a decontamination device for a surface, such as a probe, and method thereof in accordance with the present invention includes a first electrode, a second electrode, and a transformer. The first electrode comprises a housing with an opening and one end of the second electrode is positioned in the opening. The second electrode has an elongated-shape which tapers to a point at the one end adjacent to the opening. The transformer is mounted in the housing and has first and second pairs of leads. One of the second pair of leads is coupled to the first electrode and the other of the second pair of leads is coupled to the second electrode. A surface to be cleaned is placed adjacent to the point and the device is turned on for a preset period of time to generate free radicals, such as ozone plasma, which remove debris build-up on the surface.
摘要翻译：根据本发明的用于表面的去污设备（例如探针）及其方法的一个实施例包括第一电极，第二电极和变压器。第一电极包括具有开口的壳体，第二电极的一端位于开口中。第二电极具有细长形状，其逐渐变细到与开口相邻的一端的点。变压器安装在壳体中，并具有第一和第二对引线。第二对引线中的一个耦合到第一电极，并且第二对引线中的另一个耦合到第二电极。要清洁的表面被放置在该点附近，并且该装置打开预定的时间段以产生自由基，例如臭氧等离子体，其清除表面上的碎屑堆积。

7. 发明授权

US10080821B2 Nucleation of drug delivery balloons to provide improved crystal size and density 有权
公开(公告)号：US10080821B2
公开(公告)日：2018-09-25
申请号：US12815138
申请日：2010-06-14
申请人： Steve Kangas , Michael Sean Owens , Jon Patterson , Dave Ekberg , Erik Haun , Eric Henderson , Aaron Foss , Yen-Lane Chen
发明人： Steve Kangas , Michael Sean Owens , Jon Patterson , Dave Ekberg , Erik Haun , Eric Henderson , Aaron Foss , Yen-Lane Chen
IPC分类号： A61L29/16 , A61L29/06
CPC分类号： A61L29/16 , A61L29/06 , A61L2300/416 , A61L2300/606 , A61L2300/622 , A61L2300/63 , C08L77/00
摘要： Drug delivery balloons have densely packed crystals of small particle size of the drug thereon. An amorphous drug coating is applied to a balloon surface and annealed to provide the crystals. The balloon surface is nucleated to induce formation of drug crystals in the annealing step to provide the crystals in high density with small size.

8. 发明授权

US07344832B2 Method and apparatus for molecular analysis in small sample volumes 失效
标题翻译：小样本量的分子分析方法和装置
公开(公告)号：US07344832B2
公开(公告)日：2008-03-18
申请号：US10541013
申请日：2003-12-30
申请人： Eric Henderson , Curtis Mosher , Janice Huff
发明人： Eric Henderson , Curtis Mosher , Janice Huff
IPC分类号： C12Q1/68
CPC分类号： G01N33/54373 , B01J2219/00387 , B01J2219/00605 , B01J2219/00626 , B01J2219/00637 , B01J2219/00659 , B01J2219/00722 , B01J2219/00725 , C40B40/06 , C40B40/10 , C40B60/14 , G01N2035/00158 , G01Q60/42
摘要： The interrogation of extremely small sample volumes can be accomplished with the present invention. Provided are probes having disposed thereon a plurality of domains forming an array, which is suitably a nanoarray. Also provided are methods of detecting molecules and molecular interaction events, retrieving and analyzing analytes, and delivering substances to cells or tissues using probes of the invention.
摘要翻译：通过本发明可以实现极小样品体积的询问。提供了在其上设置有形成阵列的多个区域的探针，其适当地是纳米阵列。还提供了使用本发明的探针检测分子和分子相互作用事件，检索和分析分析物以及将物质递送至细胞或组织的方法。

9. 发明授权

US07080162B2 Reduced hardware network adapter and communication method 失效
公开(公告)号：US07080162B2
公开(公告)日：2006-07-18
申请号：US10682572
申请日：2003-10-08
申请人： Michael R. Conley , Eric Henderson
发明人： Michael R. Conley , Eric Henderson
IPC分类号： G06F15/16
CPC分类号： H04L12/413 , G06F13/385 , H04L12/40013 , H04L12/40032 , H04L49/90 , H04L49/9073 , Y02D10/14 , Y02D10/151
摘要： The present invention provides a network interface adapter for connecting a client computer to a computer network that includes a reduced hardware media access controller (MAC) coupled through a physical interface (PHY) to the network physical link. A significant portion of the MAC functionality is implemented as software within the processor of the host client computer. The hardware portion of the preferred MAC implementation provides memory for buffering communications between the PHY and the client computer. The preferred hardware aspects of a MAC in accordance with the present invention also includes a register interface for register-driven communications between the hardware portion of the MAC and the software portions of the MAC implemented within the client computer. By implementing most of the MAC functionality in software within the host computer, the preferred MAC provides lower cost, lower power consumption, and generally greater flexibility.

10. 发明申请

US20060035234A1 Method and apparatus for molecular analysis in small sample volumes 失效
标题翻译：小样本量的分子分析方法和装置
公开(公告)号：US20060035234A1
公开(公告)日：2006-02-16
申请号：US10541013
申请日：2003-12-30
申请人： Eric Henderson , Curtis Mosher , Janice Huff
发明人： Eric Henderson , Curtis Mosher , Janice Huff
IPC分类号： C12Q1/68 , G01N33/53 , C12M1/34
CPC分类号： G01N33/54373 , B01J2219/00387 , B01J2219/00605 , B01J2219/00626 , B01J2219/00637 , B01J2219/00659 , B01J2219/00722 , B01J2219/00725 , C40B40/06 , C40B40/10 , C40B60/14 , G01N2035/00158 , G01Q60/42
摘要： The interrogation of extremely small sample volumes can be accomplished with the present invention. Provided are probes having disposed thereon a plurality of domains forming an array, which is suitably a nanoarray. Also provided are methods of detecting molecules and molecular interaction events, retrieving and analyzing analytes, and delivering substances to cells or tissues using probes of the invention.
摘要翻译：通过本发明可以实现极小样品体积的询问。提供了在其上设置有形成阵列的多个区域的探针，其适当地是纳米阵列。还提供了使用本发明的探针检测分子和分子相互作用事件，检索和分析分析物以及将物质递送至细胞或组织的方法。

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