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1. 发明授权

US06661866B1 Integrated CT-PET system 有权
标题翻译：集成CT-PET系统
公开(公告)号：US06661866B1
公开(公告)日：2003-12-09
申请号：US10064912
申请日：2002-08-28
申请人： Mark Kenneth Limkeman , Alexander Ganin , Charles William Stearns , David Leo McDaniel , Robert Franklin Senzig
发明人： Mark Kenneth Limkeman , Alexander Ganin , Charles William Stearns , David Leo McDaniel , Robert Franklin Senzig
IPC分类号： G01N2300
CPC分类号： A61B6/032 , A61B6/027 , A61B6/037 , A61B6/4014 , A61B6/4028 , A61B6/482 , A61B6/5235
摘要： A combined emission-transmission imaging apparatus, the apparatus comprising oppositely facing first and second photon detector segments disposed on opposite sides of an imaging area and defining the imaging area there between and a radiation source disposed adjacent and outside the imaging area and adjacent at least one of the detector segments, the source generating a fan beam of radiation that emanates from a focal point and juxtaposed such that the fan beam is directed along a trajectory through the imaging area and toward the other of the detector segments, wherein the segments collect both emission and transmission radiation.
摘要翻译：一种组合发射透射成像装置，该装置包括相对面对的第一和第二光子检测器部分，其设置在成像区域的相对侧上并且限定其间的成像区域和与成像区域相邻和偏离地设置的至少一个所述源产生从焦点发出并且并置的扇形辐射束，使得所述扇形束沿着轨迹穿过所述成像区域并朝向所述检测器段中的另一个，其中所述段收集两个发射和透射辐射。

2. 发明授权

US07227149B2 Method and system for positron emission tomography image reconstruction 有权
标题翻译：正电子发射断层扫描图像重建方法与系统
公开(公告)号：US07227149B2
公开(公告)日：2007-06-05
申请号：US11026236
申请日：2004-12-30
申请人： Charles William Stearns , David Leo McDaniel , John Jay Williams , Alexander Ganin , Ravindra Mohan Manjeshwar , Floribertus Philippus Martinus Heukensfeldt Jansen , Yiping Shao
发明人： Charles William Stearns , David Leo McDaniel , John Jay Williams , Alexander Ganin , Ravindra Mohan Manjeshwar , Floribertus Philippus Martinus Heukensfeldt Jansen , Yiping Shao
IPC分类号： G01T1/164
CPC分类号： G01T1/2985
摘要： Methods and systems for controlling a positron emission tomography (PET) system are provided. The method includes receiving timing information from a PET system during an imaging scan using the PET system. The method further includes processing the received timing information and timing bias information relating to the PET system to control the PET system.
摘要翻译：提供了用于控制正电子发射断层摄影（PET）系统的方法和系统。该方法包括在使用PET系统的成像扫描期间从PET系统接收定时信息。该方法还包括处理接收到的定时信息和与PET系统有关的定时偏差信息以控制PET系统。

3. 发明授权

US07129495B2 Method and apparatus for timing calibration in a PET scanner 失效
标题翻译： PET扫描仪中定时校准的方法和装置
公开(公告)号：US07129495B2
公开(公告)日：2006-10-31
申请号：US10986792
申请日：2004-11-15
申请人： John Jay Williams , Charles William Stearns , David Leo McDaniel , Alexander Ganin
发明人： John Jay Williams , Charles William Stearns , David Leo McDaniel , Alexander Ganin
IPC分类号： G01T1/164
CPC分类号： G01T1/172 , G01T1/2985
摘要： The invention is directed to a method and apparatus for timing calibration in a PET scanner. According to one embodiment, the invention relates to a method for timing calibration in a PET scanner having a plurality of scintillator blocks. The method comprises: detecting, in a first scintillator block, a first radiation event, wherein the first scintillator block time-stamps the first radiation event; detecting, in a second scintillator block that is adjacent to the first scintillator block, a second radiation event that corresponds to the first radiation event, wherein the second scintillator block time-stamps the second radiation event; and determining a timing characteristic of the first scintillator block with respect to the second scintillator block based on a comparison between the time-stamps of the first radiation event and the second radiation event.
摘要翻译：本发明涉及一种用于在PET扫描仪中定时校准的方法和装置。根据一个实施例，本发明涉及一种具有多个闪烁体块的PET扫描器中的定时校准方法。该方法包括：在第一闪烁体块中检测第一辐射事件，其中第一闪烁体块对第一辐射事件进行时间戳; 在与所述第一闪烁体块相邻的第二闪烁器块中检测对应于所述第一辐射事件的第二辐射事件，其中所述第二闪烁体块对所述第二辐射事件进行时间戳; 以及基于所述第一辐射事件和所述第二辐射事件的时间戳之间的比较来确定所述第一闪烁体块相对于所述第二闪烁体块的定时特性。

4. 发明授权

US07301144B2 Method and system for calibrating a positron emission tomography system 有权
标题翻译：正电子发射断层扫描系统的校准方法和系统
公开(公告)号：US07301144B2
公开(公告)日：2007-11-27
申请号：US11025233
申请日：2004-12-29
申请人： John Jay Williams , Alexander Ganin , Charles William Stearns , Yiping Shao , Floribertus Philippus Martinus Heukensfeldt Jansen , Ravindra Mohan Manjeshwar
发明人： John Jay Williams , Alexander Ganin , Charles William Stearns , Yiping Shao , Floribertus Philippus Martinus Heukensfeldt Jansen , Ravindra Mohan Manjeshwar
IPC分类号： G01D18/00 , G12B13/00
CPC分类号： G01T1/2985
摘要： Methods and systems for calibrating a positron emission tomography (PET) system are provided. The method includes determining at least one non-acquisition time period for the PET system. The method further includes automatically acquiring calibration data during the at least one non-acquisition time period.
摘要翻译：提供了用于校正正电子发射断层摄影（PET）系统的方法和系统。该方法包括确定PET系统的至少一个非获取时间段。所述方法还包括在所述至少一个非采集时段期间自动获取校准数据。

5. 发明授权

US07412280B2 Systems and methods for analyzing an abnormality of an object 有权
标题翻译：用于分析物体异常的系统和方法
公开(公告)号：US07412280B2
公开(公告)日：2008-08-12
申请号：US10611296
申请日：2003-07-01
申请人： Sarah Rose Hertel , Stanley H. Fox , Alexander Ganin , Charles William Stearns
发明人： Sarah Rose Hertel , Stanley H. Fox , Alexander Ganin , Charles William Stearns
IPC分类号： A61B5/05 , A61B6/00
CPC分类号： G06T7/0012 , A61B6/032 , A61B6/037 , A61B6/5235 , G06T7/30
摘要： In one embodiment, a method for analyzing at least one abnormality of an object is described. The method includes obtaining a first image containing an abnormality using a first modality, obtaining a second image containing the abnormality using a second modality, selecting a first region of interest located within the first image, determining an anatomical size of the abnormality based on the first region of interest in the first image, and determining a relative metabolic activity based on a second region of interest within the second image.
摘要翻译：在一个实施例中，描述了用于分析对象的至少一个异常的方法。该方法包括使用第一模式获得包含异常的第一图像，使用第二模式获得包含异常的第二图像，选择位于第一图像内的第一感兴趣区域，基于第一模式确定异常的解剖尺寸第一图像中的感兴趣区域，以及基于第二图像内的第二感兴趣区域确定相对代谢活动。

6. 发明授权

US08355551B2 Method and apparatus for reducing image artifacts 有权
标题翻译：减少图像伪影的方法和装置
公开(公告)号：US08355551B2
公开(公告)日：2013-01-15
申请号：US12394772
申请日：2009-02-27
申请人： Kris Filip Johan Jules Thielemans , Scott David Wollenweber , Alexander Ganin , Anja Brau , Floribertus P. M. Heukensfeldt Jansen , Evren Asma , Rakesh Mullick , Ravindra Mohan Manjeshwar , Ajit Shankaranarayanan
发明人： Kris Filip Johan Jules Thielemans , Scott David Wollenweber , Alexander Ganin , Anja Brau , Floribertus P. M. Heukensfeldt Jansen , Evren Asma , Rakesh Mullick , Ravindra Mohan Manjeshwar , Ajit Shankaranarayanan
IPC分类号： G06K9/00
CPC分类号： G06T11/005 , G06T2211/412
摘要： A method and apparatus are provided for reducing motion related imaging artifacts. The method includes determining an internal motion for of two regions of the object, each region having a different level of motion, scanning the first region using a first scan protocol based on the motion, scanning a second region using a second different scan protocol based on the motion, and generating an image of the object based on the first and second regions.
摘要翻译：提供了一种用于减少运动相关成像伪影的方法和装置。该方法包括确定对象的两个区域的内部运动，每个区域具有不同的运动水平，基于运动使用第一扫描协议扫描第一区域，使用基于第二扫描协议的第二不同扫描协议扫描第二区域运动，以及基于第一和第二区域生成对象的图像。

7. 发明申请

US20080164875A1 EXCLUSION OF COMPROMISED PET DATA DURING SIMULTANEOUS PET-MR ACQUISITION 有权
标题翻译：同时PET-MR获取期间排除PET数据
公开(公告)号：US20080164875A1
公开(公告)日：2008-07-10
申请号：US11621622
申请日：2007-01-10
申请人： Robert H. Haworth , Steven G. Ross , Charles W. Stearns , Jason A. Polzin , Alexander Ganin
发明人： Robert H. Haworth , Steven G. Ross , Charles W. Stearns , Jason A. Polzin , Alexander Ganin
IPC分类号： G01T1/161 , G01R33/48
CPC分类号： G01R33/481 , G01R33/28 , G01T1/1603
摘要： A system and method for simultaneously acquiring PET and MR data from a subject of interest with a hybrid PET-MR scanner includes monitoring transmission times of RF and gradient coils of the MR equipment and blanking segments of the PET data stream accordingly. By excluding PET data acquired during active MR transmissions, the remaining PET data used for image reconstruction will provide improved PET image quality.
摘要翻译：利用混合PET-MR扫描仪同时从感兴趣的对象采集PET和MR数据的系统和方法包括相应地监测MR设备的RF设备和梯形线圈的传输时间以及PET数据流的消隐段。通过排除在有源MR传输期间获取的PET数据，用于图像重建的剩余PET数据将提供改进的PET图像质量。

8. 发明授权

US06914958B2 Multi-plane acquisition in digital x-ray radiography 有权
标题翻译：在数字X射线摄影中进行多平面采集
公开(公告)号：US06914958B2
公开(公告)日：2005-07-05
申请号：US09682001
申请日：2001-07-06
申请人： Alexander Ganin
发明人： Alexander Ganin
IPC分类号： A61B6/03 , A61B6/04 , H05G1/60
CPC分类号： A61B6/0457 , A61B6/032 , A61B6/469 , A61B6/488 , G06F19/00
摘要： A method is provided for acquiring digital x-ray images. Scan parameters designating slices of interest from a patient anatomy are identified. The travel distance and the speed of the x-ray tube and the detector are determined from the scan parameters. The patient is scanned in a first direction to obtain a first x-ray image utilizing a servo-tomo function based on the scan parameters. The image is saved in an image storage device and is displayed. The patient is scanned in a second direction to obtain a second x-ray image utilizing the servo-tomo function based on the scan parameters. The image is saved and displayed simultaneously with the first image in a multi-image format. After each scan, the operator may modify the scan parameters designating a slice of interest before initiating the next scan.
摘要翻译：提供了一种用于获取数字X射线图像的方法。识别从患者解剖结构指定感兴趣切片的扫描参数。从扫描参数确定X射线管和检测器的移动距离和速度。以第一方向扫描患者，以基于扫描参数获得利用伺服断层功能的第一x射线图像。图像保存在图像存储设备中并显示。基于扫描参数，利用伺服断层功能，沿第二方向扫描患者以获得第二X射线图像。图像以多图像格式与第一个图像同时保存和显示。在每次扫描之后，操作员可以在开始下一次扫描之前修改指定感兴趣的切片的扫描参数。

9. 发明授权

US06291997B1 Correction for gradient amplifier hysteresis in acquired MRI data 有权
标题翻译：获取MRI数据中梯度放大器迟滞的校正
公开(公告)号：US06291997B1
公开(公告)日：2001-09-18
申请号：US09452440
申请日：1999-12-02
申请人： Kevin F. King , Alexander Ganin , Neville D. Gai
发明人： Kevin F. King , Alexander Ganin , Neville D. Gai
IPC分类号： G01V300
CPC分类号： G01R33/56518 , G01R33/3852
摘要： Image artifacts produced by residual magnetization in elements of the gradient field amplifier system are reduced by driving the residual magnetization to a preselected value at the end of each imaging pulse sequence. Reset gradient pulses are produced by the gradient field amplifier system after each signal is acquired to drive the residual magnetization to a selected value. A number of different reset gradient waveforms may be used, and they may be produced in a number of different ways.
摘要翻译：通过在每个成像脉冲序列结束时将残余磁化驱动到预选值，减少梯度场放大器系统的元件中由残余磁化产生的图像伪影。在获取每个信号之后，由梯度场放大器系统产生复位梯度脉冲以将剩余磁化驱动到所选择的值。可以使用多个不同的复位梯度波形，并且它们可以以多种不同的方式产生。

10. 发明申请

US20120051664A1 MOTION COMPENSATION IN IMAGE PROCESSING 有权
标题翻译：图像处理中的运动补偿
公开(公告)号：US20120051664A1
公开(公告)日：2012-03-01
申请号：US12873039
申请日：2010-08-31
申请人： Girishankar Gopalakrishnan , Alexander Ganin , Ravindra Mohan Majeshwar , Kris Filip Johan Jules Thielemans , Scott David Wollenweber , Floribertus P.M. Heukensfeldt Jansen , Arunabha Shasanka Roy
发明人： Girishankar Gopalakrishnan , Alexander Ganin , Ravindra Mohan Majeshwar , Kris Filip Johan Jules Thielemans , Scott David Wollenweber , Floribertus P.M. Heukensfeldt Jansen , Arunabha Shasanka Roy
IPC分类号： G06K9/32
CPC分类号： G06T7/38 , G06T5/002 , G06T5/40 , G06T5/50 , G06T7/20 , G06T7/269 , G06T7/30 , G06T11/005 , G06T2207/10016 , G06T2207/10104 , G06T2207/10108 , G06T2207/20221 , G06T2207/30004 , G06T2211/412
摘要： Methods and systems for processing a set of images are described. In accordance with this disclosure, images are registered and an analysis is performed in view of one or more constraints (such as constraints based upon anatomical or physiological considerations). Weighting factors are determined based on the analysis. The weighting factors are used in subsequent processing of the registered (and/or unregistered) images and/or to formulate a visualization that conveys the degree of confidence in the motion estimation used in the registration process.
摘要翻译：描述用于处理一组图像的方法和系统。根据本公开，记录图像，并且根据一个或多个约束（诸如基于解剖学或生理考虑的约束）来执行分析。加权因子根据分析确定。加权因子用于后续的注册（和/或未注册）图像的处理和/或制定传达在注册过程中使用的运动估计的置信度的可视化。

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