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1. 发明授权

US09237874B2 Method and system for non-invasive imaging of a target region 有权
标题翻译：目标区域非侵入性成像的方法和系统
公开(公告)号：US09237874B2
公开(公告)日：2016-01-19
申请号：US13459585
申请日：2012-04-30
申请人： Bruno Kristiaan Bernard DeMan , James Vradenburg Miller , Floribertus P. M. Heukensfeldt Jansen
发明人： Bruno Kristiaan Bernard DeMan , James Vradenburg Miller , Floribertus P. M. Heukensfeldt Jansen
IPC分类号： G01T1/161 , A61B6/03 , G06T11/00 , A61B6/12 , A61B6/00 , A61B6/06
CPC分类号： A61B6/032 , A61B6/037 , A61B6/06 , A61B6/12 , A61B6/4021 , A61B6/4241 , A61B6/4417 , A61B6/469 , A61B6/482 , A61B6/488 , G06T11/005
摘要： Embodiments of systems, methods and non-transitory computer readable media for imaging are presented. Preliminary image data corresponding to a first FOV of a subject at a first resolution is acquired using an imaging system including one or more radiation sources and at least one hybrid detector, specifically using at least one section of the hybrid detector having the first resolution. The target ROI is identified using the preliminary image data. Further, the subject is positioned to align the target ROI along a designated axis. Additionally, parameters associated with the sources, the hybrid detector and/or an imaging system gantry are configured for acquiring target image data at a second resolution greater than the first resolution using at least one section of the hybrid detector having the second resolution. Further, one or more images corresponding to at least the target ROI are reconstructed using the target and/or the preliminary image data.
摘要翻译：提出了用于成像的系统，方法和非暂时计算机可读介质的实施例。使用包括一个或多个辐射源和至少一个混合检测器的成像系统，特别是使用具有第一分辨率的混合检测器的至少一个部分，获取与第一分辨率的对象的第一FOV相对应的初步图像数据。使用初步图像数据来识别目标ROI。此外，被摄体被定位成沿着指定轴对准目标ROI。另外，与源相关联的参数，混合检测器和/或成像系统台架被配置为使用具有第二分辨率的混合检测器的至少一个部分以大于第一分辨率的第二分辨率来获取目标图像数据。此外，使用目标和/或初步图像数据来重构与至少目标ROI相对应的一个或多个图像。

2. 发明授权

US08355551B2 Method and apparatus for reducing image artifacts 有权
标题翻译：减少图像伪影的方法和装置
公开(公告)号：US08355551B2
公开(公告)日：2013-01-15
申请号：US12394772
申请日：2009-02-27
申请人： Kris Filip Johan Jules Thielemans , Scott David Wollenweber , Alexander Ganin , Anja Brau , Floribertus P. M. Heukensfeldt Jansen , Evren Asma , Rakesh Mullick , Ravindra Mohan Manjeshwar , Ajit Shankaranarayanan
发明人： Kris Filip Johan Jules Thielemans , Scott David Wollenweber , Alexander Ganin , Anja Brau , Floribertus P. M. Heukensfeldt Jansen , Evren Asma , Rakesh Mullick , Ravindra Mohan Manjeshwar , Ajit Shankaranarayanan
IPC分类号： G06K9/00
CPC分类号： G06T11/005 , G06T2211/412
摘要： A method and apparatus are provided for reducing motion related imaging artifacts. The method includes determining an internal motion for of two regions of the object, each region having a different level of motion, scanning the first region using a first scan protocol based on the motion, scanning a second region using a second different scan protocol based on the motion, and generating an image of the object based on the first and second regions.
摘要翻译：提供了一种用于减少运动相关成像伪影的方法和装置。该方法包括确定对象的两个区域的内部运动，每个区域具有不同的运动水平，基于运动使用第一扫描协议扫描第一区域，使用基于第二扫描协议的第二不同扫描协议扫描第二区域运动，以及基于第一和第二区域生成对象的图像。

3. 发明授权

US6008494A Gamma camera stabilizer 失效
标题翻译：伽玛相机稳定器
公开(公告)号：US6008494A
公开(公告)日：1999-12-28
申请号：US1568
申请日：1997-12-31
申请人： Floribertus P. M. Heukensfeldt Jansen
发明人： Floribertus P. M. Heukensfeldt Jansen
IPC分类号： G01T1/164 , G01T1/161
CPC分类号： G01T1/1648
摘要： An apparatus and method to be used with a gamma camera for identifying and compensating for photomultiplier tube gain drift wherein a photon source is used during a customer quality control flood procedure to direct photons toward the camera and wherein the source is known to generate approximately identical numbers of photons at energies within an acquisition range of energy levels, the acquisition range having a mid-value at energy level Z, the camera is used to generate an upper image using photons having energies above level Z and within the acquisition range and to generate a lower image using photons having energies below level Z and within the acquisition range, the upper and lower images are used to identify PMTs with incorrect gain, identify gain error and then compensate for the error.
摘要翻译：一种与γ照相机一起使用以识别和补偿光电倍增管增益漂移的装置和方法，其中在客户质量控制泛洪过程期间使用光子源以将光子引向照相机，并且其中已知源产生大致相同的数字在能量级的采集范围内的能量的光子中，采集范围具有在能级Z的中间值，照相机用于使用具有高于等级Z的能量并且在获取范围内的光子产生上部图像，并且生成使用能量低于等级Z并且在采集范围内的光子的较低图像，上下图像用于识别具有不正确增益的PMT，识别增益误差，然后补偿误差。

4. 发明申请

US20100086101A1 METHOD OF AND SOFTWARE FOR CALCULATING A SCATTER ESTIMATE FOR TOMOGRAPHIC SCANNING AND SYSTEM FOR TOMOGRAPHIC SCANNING 失效
标题翻译：计算用于TOMOGRAPHIC扫描的散射估计的方法和软件以及用于TOMOGRAPHIC扫描的系统
公开(公告)号：US20100086101A1
公开(公告)日：2010-04-08
申请号：US12518334
申请日：2007-12-18
申请人： Kris Filip Johan Jules Thielemans , Charalampos Panos Tsoumpas , Floribertus P. M. Heukensfeldt Jansen
发明人： Kris Filip Johan Jules Thielemans , Charalampos Panos Tsoumpas , Floribertus P. M. Heukensfeldt Jansen
IPC分类号： H05G1/60 , G06K9/00
CPC分类号： G01T1/1647 , G06T11/005
摘要： The method calculates a scatter estimate for scatter correction of detection data from a subject in a positron emission tomographic scanner. The detection data represent the scattered events and unscattered events of annihilation photons emitted in the subject. The method uses the following steps: determine an estimate of the unscattered events; determine a simulation of the scattered events; determine a value of a scaling factor by fitting the sum of the estimate of the unscattered events and a product of the scaling factor and the simulation of the scattered events to the detection data; and determine the scatter estimate as the product of the scaling factor having said value and the simulation of the scattered events.
摘要翻译：该方法计算用于正电子发射断层摄影扫描仪中来自被摄体的检测数据的散射校正的散射估计。检测数据表示在受试者中发射的湮灭光子的分散事件和不受散射的事件。该方法使用以下步骤：确定未分散事件的估计; 确定分散事件的模拟; 通过将未散射事件的估计和缩放因子的乘积和分散事件的模拟的和拟合到检测数据来确定缩放因子的值; 并将散射估计确定为具有所述值的缩放因子与散射事件的模拟的乘积。

5. 发明授权

US07671340B2 Adjustable-focal-length collimators method and system 有权
标题翻译：可调焦距准直器的方法和系统
公开(公告)号：US07671340B2
公开(公告)日：2010-03-02
申请号：US11778290
申请日：2007-07-16
申请人： Jorge Uribe , Floribertus P. M. Heukensfeldt Jansen , James William Hugg
发明人： Jorge Uribe , Floribertus P. M. Heukensfeldt Jansen , James William Hugg
IPC分类号： G21K1/02
CPC分类号： A61B6/06 , A61B6/037
摘要： Embodiments relate to an imaging system that includes a collimator assembly having one or more pinhole apertures therein. The imaging system is configured so that one or more of the pinhole apertures has an adjustable focal length. The imaging system further includes a detector assembly configured to generate one or more signals in response to gamma rays that pass through the one or more pinhole apertures. Embodiments also relate to methods of changing collimator performance and methods of imaging a volume.
摘要翻译：实施例涉及一种成像系统，其包括其中具有一个或多个针孔的准直器组件。成像系统被配置为使得一个或多个针孔具有可调整的焦距。成像系统还包括检测器组件，其被配置为响应于穿过所述一个或多个针孔的伽马射线产生一个或多个信号。实施例还涉及改变准直器性能的方法和对体积进行成像的方法。

6. 发明授权

US07663105B2 Apparatus and method for image reconstruction for a synthetic aperture gamma ray imager 有权
标题翻译：用于合成孔径伽马射线成像仪的图像重建的装置和方法
公开(公告)号：US07663105B2
公开(公告)日：2010-02-16
申请号：US12331936
申请日：2008-12-10
申请人： Ralph Thomas Hoctor , Scott Stephen Zelakiewicz , Evren Asma , Jeffrey Gordon , Floribertus P. M. Heukensfeldt Jansen
发明人： Ralph Thomas Hoctor , Scott Stephen Zelakiewicz , Evren Asma , Jeffrey Gordon , Floribertus P. M. Heukensfeldt Jansen
IPC分类号： G01T1/00
CPC分类号： G03B42/02
摘要： An imaging system includes a platform having mounted thereon a coded-aperture imaging device and positioned to receive radiation over a baseline. The imaging system includes a computer configured to acquire a plurality of far-field datasets over the baseline, the plurality of far-field datasets comprising data received via the coded-aperture imaging device. The computer is also configured to form a preliminary image based on the acquired plurality of far-field datasets, and apply an expectation maximization (EM) algorithm to the preliminary image; wherein the EM algorithm includes an ordered subset algorithm.
摘要翻译：成像系统包括其上安装有编码孔径成像装置并被定位成在基线上接收辐射的平台。成像系统包括被配置为在基线上获取多个远场数据集的计算机，所述多个远场数据集包括经由编码孔径成像装置接收的数据。计算机还被配置为基于所获取的多个远场数据集形成初步图像，并将预期最大化（EM）算法应用于初步图像; 其中所述EM算法包括有序子集算法。

7. 发明授权

US06356619B1 Varying x-ray tube focal spot dimensions to normalize impact temperature 失效
标题翻译：不同的X射线管焦点尺寸来规范冲击温度
公开(公告)号：US06356619B1
公开(公告)日：2002-03-12
申请号：US09586435
申请日：2000-06-02
申请人： Paul G. Nagy , Floribertus P. M. Heukensfeldt Jansen
发明人： Paul G. Nagy , Floribertus P. M. Heukensfeldt Jansen
IPC分类号： H01J3506
CPC分类号： H01J35/14 , H01J35/06
摘要： In an X-ray tube having an anode supported for rotation and an annular target track mounted upon the anode, a cathode spaced apart from the anode projects a beam of electrons onto the target track within a focal spot. The cathode is designed to normalize the impact temperature across the focal spot, as a function of length. In accordance therewith, the cathode comprises a filament and a cathode cup, wherein the filament is disposed to project the electron beam onto the target track to generate X-rays, when a high voltage potential difference is established between the filament and the anode. The filament and the cathode cup are respectively configured to selectively form the electron beam so that the beam provides an electron distribution within the focal point which maintains each point within the focal spot at substantially the same temperature.
摘要翻译：在具有被支撑为旋转的阳极和安装在阳极上的环形目标轨道的X射线管中，与阳极间隔开的阴极在焦点内将一束电子投射到目标轨迹上。阴极被设计成使焦点上的冲击温度归一化为长度的函数。根据此，阴极包括细丝和阴极杯，其中当灯丝和阳极之间建立高电压电位差时，灯丝设置成将电子束投射到靶轨道上以产生X射线。灯丝和阴极杯分别被配置成选择性地形成电子束，使得光束在焦点内提供电子分布，其将焦点内的每个点保持在基本相同的温度。

8. 发明授权

US08923484B2 Motion correction system and method for an x-ray tube 有权
标题翻译： X射线管的运动校正系统和方法
公开(公告)号：US08923484B2
公开(公告)日：2014-12-30
申请号：US13602080
申请日：2012-08-31
申请人： Yun Zou , Scott Stephen Zelakiewicz , Floribertus P. M. Heukensfeldt Jansen , Jeffrey Wayne Eberhard , Fengfeng Tao , Timothy Powers , Thomas Edmund Sjoberg
发明人： Yun Zou , Scott Stephen Zelakiewicz , Floribertus P. M. Heukensfeldt Jansen , Jeffrey Wayne Eberhard , Fengfeng Tao , Timothy Powers , Thomas Edmund Sjoberg
IPC分类号： H01J35/28 , H01J35/24 , H01J35/14
CPC分类号： H01J35/28 , H01J35/025 , H01J35/14
摘要： A motion correction system and method for motion correction for an x-ray tube is presented. One embodiment of the motion correction system includes a sensing unit coupled to an x-ray tube to determine a distance with which an impingement location of an electron beam generated by the x-ray tube deviates from a determined location due to motion of the x-ray tube. The motion correction system further includes a control unit coupled to the sensing unit to generate a control signal corresponding to the distance with which the impingement location of the electron beam deviates. Also, the motion correction system includes a deflection unit coupled to the control unit to steer the electron beam to the determined location based on the generated control signal.
摘要翻译：提出了用于X射线管的运动校正系统和运动校正方法。运动校正系统的一个实施例包括耦合到X射线管的感测单元，以确定由x射线管产生的电子束的冲击位置由于X射线管的运动而偏离确定的位置的距离，射线管。运动校正系统还包括耦合到感测单元的控制单元，以产生对应于电子束的冲击位置偏离的距离的控制信号。此外，运动校正系统包括耦合到控制单元的偏转单元，以基于所生成的控制信号将电子束转向确定的位置。

9. 发明授权

US08552389B2 System and method for collimation in diagnostic imaging systems 有权
标题翻译：诊断成像系统准直的系统和方法
公开(公告)号：US08552389B2
公开(公告)日：2013-10-08
申请号：US12915873
申请日：2010-10-29
申请人： Floribertus P. M. Heukensfeldt Jansen , Yaron Hefetz
发明人： Floribertus P. M. Heukensfeldt Jansen , Yaron Hefetz
IPC分类号： G21K1/02
CPC分类号： A61B6/037 , A61B6/06 , A61B6/4258 , A61B6/4291 , A61B6/501 , A61B6/54 , G21K1/025
摘要： A system and method for collimation in diagnostic imaging systems is provided. One collimation system includes a collimator for a radiation imaging detector having a plurality of adjustable segments and a plurality of collimator holes within each of the plurality of adjustable segments. The plurality of adjustable segments are configured to move independently of a detector to adjust a field of view of the collimator holes.
摘要翻译：提供了诊断成像系统中准直的系统和方法。一个准直系统包括用于辐射成像检测器的准直器，其具有多个可调节段和多个可调节段内的多个准直器孔。多个可调节段被构造成独立于检测器移动以调节准直器孔的视场。

10. 发明授权

US08269177B2 Multiplexing readout scheme for a gamma ray detector 有权
标题翻译：伽马射线探测器的多路复用读出方案
公开(公告)号：US08269177B2
公开(公告)日：2012-09-18
申请号：US12714529
申请日：2010-02-28
申请人： Chang Lyong Kim , David McDaniel , Floribertus P. M. Heukensfeldt Jansen
发明人： Chang Lyong Kim , David McDaniel , Floribertus P. M. Heukensfeldt Jansen
IPC分类号： G01T1/166
CPC分类号： G01T1/2985 , A61B6/037
摘要： A method and apparatus for producing a PET image of a tissue using a PET scanner that includes scintillation crystals and detectors. A first crystal group including a first subset of crystals is formed, and a second crystal group including a second subset of the crystals is formed. The crystals in the first crystal group are different from crystals in the second crystal group A first beam striking one or more crystals of the first crystal group is converted to a first electrical signal, while a second beam striking one or more crystals of the second crystal group is converted to a second electrical signal, wherein the second beam is scattered from the first beam. The second electrical signal is corrected using a correction factor derived from at least one of a first and second timing relationships to compensate for energy in the second signal scattered from the first signal. An image of the tissue is created using the corrected second electrical signal.
摘要翻译：一种使用包括闪烁晶体和检测器的PET扫描仪来生产组织的PET图像的方法和装置。形成包括晶体的第一子集的第一晶体组，并且形成包括晶体的第二子集的第二晶体组。第一晶体组中的晶体与第二晶体组中的晶体不同。将第一晶体组中的一个或多个晶体的第一光束转换为第一电信号，而第二光束撞击第二晶体的一个或多个晶体组被转换为第二电信号，其中第二光束从第一光束散射。使用从第一和第二定时关系中的至少一个导出的校正因子校正第二电信号，以补偿从第一信号散射的第二信号中的能量。使用校正的第二电信号创建组织的图像。

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