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1. 发明授权

US07227149B2 Method and system for positron emission tomography image reconstruction 有权
标题翻译：正电子发射断层扫描图像重建方法与系统
公开(公告)号：US07227149B2
公开(公告)日：2007-06-05
申请号：US11026236
申请日：2004-12-30
申请人： Charles William Stearns , David Leo McDaniel , John Jay Williams , Alexander Ganin , Ravindra Mohan Manjeshwar , Floribertus Philippus Martinus Heukensfeldt Jansen , Yiping Shao
发明人： Charles William Stearns , David Leo McDaniel , John Jay Williams , Alexander Ganin , Ravindra Mohan Manjeshwar , Floribertus Philippus Martinus Heukensfeldt Jansen , Yiping Shao
IPC分类号： G01T1/164
CPC分类号： G01T1/2985
摘要： Methods and systems for controlling a positron emission tomography (PET) system are provided. The method includes receiving timing information from a PET system during an imaging scan using the PET system. The method further includes processing the received timing information and timing bias information relating to the PET system to control the PET system.
摘要翻译：提供了用于控制正电子发射断层摄影（PET）系统的方法和系统。该方法包括在使用PET系统的成像扫描期间从PET系统接收定时信息。该方法还包括处理接收到的定时信息和与PET系统有关的定时偏差信息以控制PET系统。

2. 发明授权

US07301144B2 Method and system for calibrating a positron emission tomography system 有权
标题翻译：正电子发射断层扫描系统的校准方法和系统
公开(公告)号：US07301144B2
公开(公告)日：2007-11-27
申请号：US11025233
申请日：2004-12-29
申请人： John Jay Williams , Alexander Ganin , Charles William Stearns , Yiping Shao , Floribertus Philippus Martinus Heukensfeldt Jansen , Ravindra Mohan Manjeshwar
发明人： John Jay Williams , Alexander Ganin , Charles William Stearns , Yiping Shao , Floribertus Philippus Martinus Heukensfeldt Jansen , Ravindra Mohan Manjeshwar
IPC分类号： G01D18/00 , G12B13/00
CPC分类号： G01T1/2985
摘要： Methods and systems for calibrating a positron emission tomography (PET) system are provided. The method includes determining at least one non-acquisition time period for the PET system. The method further includes automatically acquiring calibration data during the at least one non-acquisition time period.
摘要翻译：提供了用于校正正电子发射断层摄影（PET）系统的方法和系统。该方法包括确定PET系统的至少一个非获取时间段。所述方法还包括在所述至少一个非采集时段期间自动获取校准数据。

3. 发明授权

US07381959B2 Technique for reconstructing PET scan images 有权
标题翻译： PET扫描图像重建技术
公开(公告)号：US07381959B2
公开(公告)日：2008-06-03
申请号：US11205067
申请日：2005-08-17
申请人： Ravindra Mohan Manjeshwar , Floribertus Philippus Martinus Heukensfeldt Jansen , Charles William Stearns
发明人： Ravindra Mohan Manjeshwar , Floribertus Philippus Martinus Heukensfeldt Jansen , Charles William Stearns
IPC分类号： G01T1/163
CPC分类号： G01T1/2985
摘要： The invention is directed to a technique for reconstructing PET scan images. According to one embodiment, the invention relates to a method for reconstructing PET scan images. The method comprises: detecting a plurality of coincidence events in a PET scanner; storing data associated with the plurality of coincidence events in a chronological list based on a detection time for each of the plurality of coincidence events; generating correction data based on scatter coincidence events and random coincidence events in the plurality of coincidence events; and reconstructing one or more PET scan images based at least in part on the chronological list of data and the correction data.
摘要翻译：本发明涉及一种重建PET扫描图像的技术。根据一个实施例，本发明涉及一种重建PET扫描图像的方法。该方法包括：在PET扫描器中检测多个符合事件; 基于多个重合事件中的每一个的检测时间，将与所述多个符合事件相关联的数据存储在时序列表中; 基于所述多个重合事件中的分散符合事件和随机符合事件生成校正数据; 以及至少部分地基于时间顺序的数据列表和校正数据重建一个或多个PET扫描图像。

4. 发明授权

US07680240B2 Iterative reconstruction of tomographic image data method and system 有权
标题翻译：断层图像数据方法和系统的迭代重建
公开(公告)号：US07680240B2
公开(公告)日：2010-03-16
申请号：US11731612
申请日：2007-03-30
申请人： Ravindra Mohan Manjeshwar , Floribertus Philippus Martinus Heukensfeldt Jansen , James William Hugg , Charles William Stearns
发明人： Ravindra Mohan Manjeshwar , Floribertus Philippus Martinus Heukensfeldt Jansen , James William Hugg , Charles William Stearns
IPC分类号： A61B6/00
CPC分类号： A61B6/032 , A61B6/037 , A61B6/469 , G06T11/006 , G06T2211/424 , G06T2211/432
摘要： Methods for performing image reconstruction that include deriving background projection data for an area outside a targeted field of view of a tomographic image, and reconstructing the tomographic image of the targeted field of view, wherein the background projection data is used in the reconstruction. Methods for selecting a reconstruction methodology that include determining a number of pixels in a reconstructed image for a first reconstruction methodology, determining a number of pixels in a reconstructed image for a second reconstruction methodology, comparing the number of pixels for the first reconstruction methodology and the number of pixels for the second reconstruction methodology, and selecting the reconstruction methodology for image reconstruction based on the comparison of the number of pixels. Imaging systems implementing these methods are also provided.
摘要翻译：用于执行图像重建的方法，包括导出用于断层图像的目标视场外的区域的背景投影数据，以及重构所述目标视场的断层图像，其中所述背景投影数据用于所述重建。用于选择重建方法的方法，所述重建方法包括确定用于第一重建方法的重建图像中的像素数量，确定用于第二重建方法的重建图像中的像素数量，将第一重建方法的像素数与用于第二重建方法的像素数量，以及基于像素数目的比较来选择用于图像重建的重建方法。还提供了实现这些方法的成像系统。

5. 发明授权

US07312455B2 Method and system for scatter correction in a positron emission tomography system 有权
标题翻译：正电子发射断层扫描系统中散射校正的方法和系统
公开(公告)号：US07312455B2
公开(公告)日：2007-12-25
申请号：US11034166
申请日：2005-01-12
申请人： Ravindra Mohan Manjeshwar , Floribertus Philippus Martinus Heukensfeldt Jansen , Charles William Stearns
发明人： Ravindra Mohan Manjeshwar , Floribertus Philippus Martinus Heukensfeldt Jansen , Charles William Stearns
IPC分类号： G01T1/164
CPC分类号： G01T1/2985 , A61B6/037
摘要： Methods and systems for providing scatter correction in a positron emission tomography (PET) system are provided. The method includes determining a look-up table of scatter sinograms during a PET acquisition scan period. The method further includes scatter correcting acquired scan data obtained during the PET acquisition scan period.
摘要翻译：提供了在正电子发射断层摄影（PET）系统中提供散射校正的方法和系统。该方法包括在PET采集扫描周期期间确定散射正弦图的查找表。该方法还包括在PET采集扫描周期期间获得的获取的扫描数据的散射校正。

6. 发明授权

US07405405B2 Method and system for reconstructing an image in a positron emission tomography (PET) system 有权
标题翻译：用于在正电子发射断层摄影（PET）系统中重建图像的方法和系统
公开(公告)号：US07405405B2
公开(公告)日：2008-07-29
申请号：US11131149
申请日：2005-05-17
申请人： Charles William Stearns , Ravindra Mohan Manjeshwar , Floribertus Philippus Martinus Heukensfeldt Jansen
发明人： Charles William Stearns , Ravindra Mohan Manjeshwar , Floribertus Philippus Martinus Heukensfeldt Jansen
IPC分类号： G01T1/164
CPC分类号： G01T1/2985
摘要： A method and system for reconstructing an image in a time-of-flight (TOF) positron emission tomography (PET) system is provided. The method includes using a reconstructed image to determine predicted timing information. Timing bias data is updated based on received timing information associated with acquired scan data from a PET system and the predicted timing information. The method further includes reconstructing the image, based on the updated timing bias data.
摘要翻译：提供了一种用于在飞行时间（TOF）正电子发射断层摄影（PET）系统中重建图像的方法和系统。该方法包括使用重构图像来确定预测的定时信息。基于与来自PET系统的获取的扫描数据相关联的接收定时信息和预测的定时信息来更新定时偏差数据。该方法还包括基于更新的定时偏差数据重建图像。

7. 发明授权

US07129495B2 Method and apparatus for timing calibration in a PET scanner 失效
标题翻译： PET扫描仪中定时校准的方法和装置
公开(公告)号：US07129495B2
公开(公告)日：2006-10-31
申请号：US10986792
申请日：2004-11-15
申请人： John Jay Williams , Charles William Stearns , David Leo McDaniel , Alexander Ganin
发明人： John Jay Williams , Charles William Stearns , David Leo McDaniel , Alexander Ganin
IPC分类号： G01T1/164
CPC分类号： G01T1/172 , G01T1/2985
摘要： The invention is directed to a method and apparatus for timing calibration in a PET scanner. According to one embodiment, the invention relates to a method for timing calibration in a PET scanner having a plurality of scintillator blocks. The method comprises: detecting, in a first scintillator block, a first radiation event, wherein the first scintillator block time-stamps the first radiation event; detecting, in a second scintillator block that is adjacent to the first scintillator block, a second radiation event that corresponds to the first radiation event, wherein the second scintillator block time-stamps the second radiation event; and determining a timing characteristic of the first scintillator block with respect to the second scintillator block based on a comparison between the time-stamps of the first radiation event and the second radiation event.
摘要翻译：本发明涉及一种用于在PET扫描仪中定时校准的方法和装置。根据一个实施例，本发明涉及一种具有多个闪烁体块的PET扫描器中的定时校准方法。该方法包括：在第一闪烁体块中检测第一辐射事件，其中第一闪烁体块对第一辐射事件进行时间戳; 在与所述第一闪烁体块相邻的第二闪烁器块中检测对应于所述第一辐射事件的第二辐射事件，其中所述第二闪烁体块对所述第二辐射事件进行时间戳; 以及基于所述第一辐射事件和所述第二辐射事件的时间戳之间的比较来确定所述第一闪烁体块相对于所述第二闪烁体块的定时特性。

8. 发明申请

US20110150306A1 APPARATUS AND METHODS FOR DETERMINING A BOUNDARY OF AN OBJECT FOR POSITRON EMISSION TOMOGRAPHY SCATTER CORRECTION 有权
标题翻译：用于确定POSI发射平面扫描校正的对象边界的装置和方法
公开(公告)号：US20110150306A1
公开(公告)日：2011-06-23
申请号：US12643735
申请日：2009-12-21
申请人： Steven Gerard Ross , Timothy Wayne Deller , Ravindra Mohan Manjeshwar , Scott David Wollenweber , Charles William Stearns
发明人： Steven Gerard Ross , Timothy Wayne Deller , Ravindra Mohan Manjeshwar , Scott David Wollenweber , Charles William Stearns
IPC分类号： G06K9/62 , H05G1/60 , G01T1/166
CPC分类号： A61B6/032 , A61B6/037 , A61B6/5211 , G01T1/1611 , G01T1/2985 , G06T11/005
摘要： Apparatus and methods for determining a boundary of an object for positron emission tomography (PET) scatter correction are provided. One method includes obtaining positron emission tomography (PET) data and computed tomography (CT) data for an object. The PET data and CT data is acquired from an imaging system. The method further includes determining a PET data boundary of the object based on the PET data and determining a CT data boundary of the object based on the CT data. The method further includes determining a combined boundary for PET scatter correction. The combined boundary encompasses the PET data boundary and the CT data boundary.
摘要翻译：提供了用于确定正电子发射断层摄影（PET）散射校正物体边界的装置和方法。一种方法包括获得对象的正电子发射断层摄影（PET）数据和计算机断层摄影（CT）数据。从成像系统获取PET数据和CT数据。该方法还包括基于PET数据确定对象的PET数据边界，并且基于CT数据确定对象的CT数据边界。该方法还包括确定PET散射校正的组合边界。组合边界包含PET数据边界和CT数据边界。

9. 发明申请

US20080240335A1 Iterative reconstruction of tomographic image data method and system 有权
标题翻译：断层图像数据方法和系统的迭代重建
公开(公告)号：US20080240335A1
公开(公告)日：2008-10-02
申请号：US11731612
申请日：2007-03-30
申请人： Ravindra Mohan Manjeshwar , Floribertus Philippus Martinus Henkensfeldt Jansen , James William Hugg , Charles William Stearns
发明人： Ravindra Mohan Manjeshwar , Floribertus Philippus Martinus Henkensfeldt Jansen , James William Hugg , Charles William Stearns
IPC分类号： A61B6/00
CPC分类号： A61B6/032 , A61B6/037 , A61B6/469 , G06T11/006 , G06T2211/424 , G06T2211/432
摘要： Methods for performing image reconstruction that include deriving background projection data for an area outside a targeted field of view of a tomographic image, and reconstructing the tomographic image of the targeted field of view, wherein the background projection data is used in the reconstruction. Methods for selecting a reconstruction methodology that include determining a number of pixels in a reconstructed image for a first reconstruction methodology, determining a number of pixels in a reconstructed image for a second reconstruction methodology, comparing the number of pixels for the first reconstruction methodology and the number of pixels for the second reconstruction methodology, and selecting the reconstruction methodology for image reconstruction based on the comparison of the number of pixels. Imaging systems implementing these methods are also provided.
摘要翻译：用于执行图像重建的方法，包括导出用于断层图像的目标视场外的区域的背景投影数据，以及重构所述目标视场的断层图像，其中所述背景投影数据用于所述重建。用于选择重建方法的方法，所述重建方法包括确定用于第一重建方法的重建图像中的像素数量，确定用于第二重建方法的重建图像中的像素数量，将第一重建方法的像素数与用于第二重建方法的像素数量，以及基于像素数目的比较来选择用于图像重建的重建方法。还提供了实现这些方法的成像系统。

10. 发明授权

US08415630B2 Apparatus and methods for determining a boundary of an object for positron emission tomography scatter correction 有权
标题翻译：用于确定正电子发射断层扫描物体的边界的装置和方法
公开(公告)号：US08415630B2
公开(公告)日：2013-04-09
申请号：US12643735
申请日：2009-12-21
申请人： Steven Gerard Ross , Timothy Wayne Deller , Ravindra Mohan Manjeshwar , Scott David Wollenweber , Charles William Stearns
发明人： Steven Gerard Ross , Timothy Wayne Deller , Ravindra Mohan Manjeshwar , Scott David Wollenweber , Charles William Stearns
IPC分类号： G01T1/161 , G01T1/166 , A61B6/00
CPC分类号： A61B6/032 , A61B6/037 , A61B6/5211 , G01T1/1611 , G01T1/2985 , G06T11/005
摘要： Apparatus and methods for determining a boundary of an object for positron emission tomography (PET) scatter correction are provided. One method includes obtaining positron emission tomography (PET) data and computed tomography (CT) data for an object. The PET data and CT data is acquired from an imaging system. The method further includes determining a PET data boundary of the object based on the PET data and determining a CT data boundary of the object based on the CT data. The method further includes determining a combined boundary for PET scatter correction. The combined boundary encompasses the PET data boundary and the CT data boundary.
摘要翻译：提供了用于确定正电子发射断层摄影（PET）散射校正物体边界的装置和方法。一种方法包括获得对象的正电子发射断层摄影（PET）数据和计算机断层摄影（CT）数据。从成像系统获取PET数据和CT数据。该方法还包括基于PET数据确定对象的PET数据边界，并且基于CT数据确定对象的CT数据边界。该方法还包括确定PET散射校正的组合边界。组合边界包含PET数据边界和CT数据边界。

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