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1. 发明申请

US20080269249A2 AMINOPYRAZINE ANALOGS FOR TREATING GLAUCOMA AND OTHER RHO KINASE-MEDIATED DISEASES AND CONDITIONS 审中-公开
标题翻译：用于治疗葡萄球菌和其他RHO激酶介导的疾病和病症的氨基吡嗪类似物
公开(公告)号：US20080269249A2
公开(公告)日：2008-10-30
申请号：US11302825
申请日：2005-12-14
申请人： Mark Hellberg , Andrew Rusinko , Alan Henderson , Cheng Guo , Mark Hadden , Helene Decornez
发明人： Mark Hellberg , Andrew Rusinko , Alan Henderson , Cheng Guo , Mark Hadden , Helene Decornez
IPC分类号： A61K31/497 , C07D403/02 , A61K31/4965
CPC分类号： C07D471/04 , A61K31/4965 , A61K31/497 , C07D401/04 , C07D401/14 , C07D403/14
摘要： Methods for using aminopyrazine analogs to treat rho kinase-mediated diseases or rho kinase-mediated conditions, including controlling intraocular pressure and treating glaucoma, are disclosed. Ophthalmic pharmaceutical compositions useful in the treatment of eye diseases such as glaucoma, and additionally useful for controlling intraocular pressure, the compositions comprising an effective amount of aminopyrazine analogs, are also disclosed.
摘要翻译：公开了使用氨基吡嗪类似物治疗rho激酶介导的疾病或rho激酶介导的病症（包括控制眼内压和治疗青光眼）的方法。还公开了可用于治疗眼睛疾病例如青光眼并且还可用于控制眼内压的眼用药物组合物，所述组合物包含有效量的氨基吡嗪类似物。

2. 发明授权

US09359183B2 Flavored pouring dispenser 有权
标题翻译：调味浇注机
公开(公告)号：US09359183B2
公开(公告)日：2016-06-07
申请号：US13829480
申请日：2013-03-14
申请人： Alan Henderson
发明人： Alan Henderson
IPC分类号： A47J31/06 , B67D3/00
CPC分类号： B67D3/0003 , B67D3/0041 , B67D3/0051
摘要： A bottle pouring dispenser featuring a dispenser housing having a lower end configured to be removably attached to and cover an open end of a bottle. The bottle pouring dispenser includes a valve providing one-way hydraulic communication from the bottle to a chamber defined within the dispenser housing. The dispenser housing has upper and lower chamber portions. A flavorant is disposed within the upper chamber portion in solid form and it is dissolvable in liquid so as to add flavoring to liquid flowing through the chamber. The flavorant is held spaced above a floor of the chamber, such that a lower portion of the chamber defines a drain volume beneath the flavorant for receiving liquid draining from about the flavorant. The bottle pouring dispenser further includes a pour spout extending from an upper end of the dispenser housing, for dispensing the flavored liquid from the chamber.
摘要翻译：一种具有分配器壳体的瓶子浇注分配器，其具有构造成可移除地附接到瓶盖的开口端并覆盖瓶子的开口端的下端。瓶子浇注分配器包括提供从瓶子到限定在分配器壳体内的室的单向液压连通的阀。分配器壳体具有上室和下室部分。调味剂以固体形式设置在上室部分内，并且其可溶于液体中，以便对流过该室的液体添加调味剂。风味剂被保持在室的地板上方间隔开，使得室的下部限定了香料下方的排放体积，用于接收从食用香料中排出的液体。瓶子浇注分配器还包括从分配器壳体的上端延伸的倾倒口，用于从腔室分配调味液体。

3. 发明申请

US20140173839A1 OMNIDIRECTIONAL ORAL CARE BRUSH 有权
公开(公告)号：US20140173839A1
公开(公告)日：2014-06-26
申请号：US14135986
申请日：2013-12-20
申请人： Alan Henderson
发明人： Alan Henderson
IPC分类号： A46B9/04 , A46D3/00
CPC分类号： A46D3/00 , A46B5/023 , A46B9/045 , A46B15/0097 , A61C17/3418 , A61C17/3481
摘要： A toothbrush featuring a graspable elongated handle defining a longitudinal axis, the handle comprising a neck region adjacent an end of the handle and a head disposed at the end of the handle. The head is carrying flexible bristles that extend outward from an outer surface of the head. The outer surface of the head is axisymmetric. The bristles are distributed about the head such that bristles extend in each of several radial directions, including from opposite sides of the head. At least some of the bristles are extending so as to overlay the longitudinal axis in opposite directions.
摘要翻译：一种具有限定纵向轴线的可抓握细长手柄的牙刷，所述手柄包括邻近所述手柄的端部的颈部区域和设置在所述手柄的端部处的头部。头部承载从头部的外表面向外延伸的柔性刷毛。头部的外表面是轴对称的。刷毛围绕头部分布，使得刷毛在几个径向方向中的每一个中延伸，包括从头部的相对侧。至少一些刷毛延伸以便在相反的方向上覆盖纵向轴线。

4. 发明申请

US20060014780A1 Nicotinamide derivatives useful as PDE4 inhibitors 审中-公开
公开(公告)号：US20060014780A1
公开(公告)日：2006-01-19
申请号：US11229395
申请日：2005-09-16
申请人： Simon Bailey , Elisabeth Gautier , Alan Henderson , Thomas Magee , Anthony Marfat , John Mathias , Dale McLeod , Sandra Monaghan , Blanda Stammen
发明人： Simon Bailey , Elisabeth Gautier , Alan Henderson , Thomas Magee , Anthony Marfat , John Mathias , Dale McLeod , Sandra Monaghan , Blanda Stammen
IPC分类号： A61K31/46 , A61K31/4545 , A61K31/4433 , A61K31/4415 , C07D405/02 , C07D401/02 , C07D453/02
CPC分类号： C07D213/82 , A61K31/4433 , A61K31/455 , A61K31/46 , A61K31/537 , A61K45/06 , C07D401/12 , C07D405/12 , C07D451/04 , C07D451/10 , Y02A50/411 , A61K2300/00
摘要： The invention relates to nicotinamide derivatives and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The nicotinamide derivatives according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic, respiratory diseases, disorders and conditions, as well as wounds.

5. 发明申请

US20140260997A1 FLAVORED POURING DISPENSER 有权
标题翻译：漂白的分配器
公开(公告)号：US20140260997A1
公开(公告)日：2014-09-18
申请号：US13829480
申请日：2013-03-14
申请人： Alan Henderson
发明人： Alan Henderson
IPC分类号： A47J31/46
CPC分类号： B67D3/0003 , B67D3/0041 , B67D3/0051
摘要： A bottle pouring dispenser featuring a dispenser housing having a lower end configured to be removably attached to and cover an open end of a bottle. The bottle pouring dispenser includes a valve providing one-way hydraulic communication from the bottle to a chamber defined within the dispenser housing. The dispenser housing has upper and lower chamber portions. A flavorant is disposed within the upper chamber portion in solid form and it is dissolvable in liquid so as to add flavoring to liquid flowing through the chamber. The flavorant is held spaced above a floor of the chamber, such that a lower portion of the chamber defines a drain volume beneath the flavorant for receiving liquid draining from about the flavorant. The bottle pouring dispenser further includes a pour spout extending from an upper end of the dispenser housing, for dispensing the flavored liquid from the chamber.
摘要翻译：一种具有分配器壳体的瓶子浇注分配器，其具有构造成可移除地附接到瓶盖的开口端并覆盖瓶子的开口端的下端。瓶子浇注分配器包括提供从瓶子到限定在分配器壳体内的室的单向液压连通的阀。分配器壳体具有上室和下室部分。调味剂以固体形式设置在上室部分内，并且其可溶于液体中，以便对流过该室的液体添加调味剂。风味剂被保持在室的地板上方间隔开，使得室的下部限定了香料下方的排放体积，用于接收从食用香料中排出的液体。瓶子浇注分配器还包括从分配器壳体的上端延伸的倾倒口，用于从腔室分配调味液体。

6. 发明申请

US20130061984A1 MULTI-FUNCTIONAL AND MODULAR TREE REMOVAL AND MAINTENANCE APPARATUS AND RELATED METHODS 有权
标题翻译：多功能和模块化树木移除和维护装置及相关方法
公开(公告)号：US20130061984A1
公开(公告)日：2013-03-14
申请号：US13608837
申请日：2012-09-10
申请人： John Helmsderfer , Stuart McDowell , Florin Arabei , Alex Androski , Alan Henderson
发明人： John Helmsderfer , Stuart McDowell , Florin Arabei , Alex Androski , Alan Henderson
IPC分类号： A01G23/06
CPC分类号： A01G23/06 , A01G23/067
摘要： A lifting apparatus is provided. The apparatus includes a primary body that has a support for supporting a person, and a secondary body. A releasable coupling provides selective coupling between the primary and secondary bodies. The lifting apparatus has (a) a first condition in which the primary body is coupled to the secondary body, and (b) a second condition in which the primary body is not coupled to the secondary body, and is configured to be releasably coupled to a vehicle.
摘要翻译：提供提升装置。该装置包括具有用于支撑人的支撑件的主体和次体。可释放的联接器提供主体和次体之间的选择性联接。提升装置具有（a）第一状态，其中主体联接到次体，和（b）第二状态，其中主体未联接到次体，并且构造成可释放地联接到一辆车。

7. 发明申请

US20060191772A1 Tensioning assembly for conveying belt cleaning blade 有权
标题翻译：用于输送皮带清洁刮板的张紧组件
公开(公告)号：US20060191772A1
公开(公告)日：2006-08-31
申请号：US11068685
申请日：2005-02-28
申请人： Daniel Wiggins , Robert Airaudi , Robert Welker , Alan Henderson , Jeremy Nylund , Gregory Cappaert
发明人： Daniel Wiggins , Robert Airaudi , Robert Welker , Alan Henderson , Jeremy Nylund , Gregory Cappaert
IPC分类号： B65G45/16
CPC分类号： B65G45/16
摘要： A tensioning system for a cleaning blade for a conveying belt. The tensioning system has a frame, a blade support, and a ratchet system. The blade support is movable around a first axis in a first direction to increase cleaning blade pressure and a second direction oppositely to the first direction to decrease cleaning blade pressure. Through the ratchet system, a position of the blade support can be maintained against pivoting in the second direction. The ratchet system has (a) a first ratchet assembly on one of the frame and blade support with at least one ratchet surface facing in a first circumferential direction relative to the first axis and (b) a second ratchet assembly on the other of the frame and blade support and having a first plurality of ratchet surfaces facing in a second circumferential direction oppositely to the first circumferential direction. At least a part of at least one of the first and second ratchet assemblies is deformable to allow the blade support to pivot in the first direction to cause the one ratchet surface to (a) move circumferentially up to and sequentially past each of the ratchet surfaces in the first plurality of ratchet surfaces as an incident of the blade support moving in the first direction around the first axis and (b) abut one of the ratchet surfaces in the first plurality of ratchet surfaces to block movement of the blade support in the second direction around the first axis.
摘要翻译：用于输送带的清洁刮板的张紧系统。张紧系统具有框架，刀片支撑件和棘轮系统。刀片支撑件可沿第一方向围绕第一轴线移动以增加清洁刀片压力和与第一方向相反的第二方向以降低清洁刀片压力。通过棘轮系统，可以保持刀片支撑件的位置以防止在第二方向上的枢转。棘轮系统具有（a）在框架和叶片支撑件之一上的第一棘轮组件，其中相对于第一轴线具有面向第一圆周方向的至少一个棘轮表面和（b）在框架的另一个上的第二棘轮组件和叶片支撑件，并且具有面向与第一圆周方向相反的第二圆周方向的第一多个棘轮表面。第一棘轮组件和第二棘轮组件中的至少一个的至少一部分是可变形的，以允许叶片支撑件沿第一方向枢转，以使一个棘轮表面（a）沿周向上移动并依次经过每个棘轮表面在所述第一多个棘轮表面中，所述刀片支撑件的入射围绕所述第一轴线沿所述第一方向移动，并且（b）邻接所述第一多个棘轮表面中的一个所述棘轮表面以阻挡所述刀片支撑件在所述第二棘轮表面中的运动方向围绕第一轴。

8. 发明申请

US20060054748A1 Apparatus and method for manufacturing a rock bolt 失效
标题翻译：用于制造岩石锚杆的装置和方法
公开(公告)号：US20060054748A1
公开(公告)日：2006-03-16
申请号：US11220254
申请日：2005-09-06
申请人： Mieczyslaw Rataj , Alan Henderson , Albert Taylor
发明人： Mieczyslaw Rataj , Alan Henderson , Albert Taylor
IPC分类号： F16L3/08
CPC分类号： B21K1/46 , B21F5/00 , B21J5/08 , D07B7/187 , E21D21/006
摘要： An apparatus for manufacturing a cable bolt from a cable (1) includes first and second clamps (2, 3) adapted to releasably clamp the cable (1) with the cable (1) extending along the longitudinal axis (4) of the apparatus. A first cable displacement device (12) longitudinally displaces the first clamp (2) relative to the second clamp (3) along the longitudinal axis (4). A first clamp rotation device (14) rotates the first clamp (2) relative to the second clamp (3) about the longitudinal axis (4). The apparatus also has a second clamp displacement device (19) for simultaneously longitudinally displacing the first and second clamps (2, 3) along the longitudinal axis (4).
摘要翻译：用于从电缆（1）制造电缆螺栓的装置包括适于可释放地夹紧电缆（1）的第一和第二夹具（2,3），其中电缆（1）沿着装置的纵向轴线（4）延伸。第一缆索位移装置（12）沿着纵向轴线（4）相对于第二夹具（3）纵向地移动第一夹具（2）。第一夹紧旋转装置（14）围绕纵向轴线（4）相对于第二夹具（3）旋转第一夹具（2）。该装置还具有用于同时沿着纵向轴线（4）纵向移位第一和第二夹具（2,3）的第二夹持位移装置（19）。

9. 发明授权

US09357837B2 Omnidirectional oral care brush 有权
标题翻译：全方位口腔护理刷
公开(公告)号：US09357837B2
公开(公告)日：2016-06-07
申请号：US14135986
申请日：2013-12-20
申请人： Alan Henderson
发明人： Alan Henderson
IPC分类号： A46D3/00 , A46B5/02 , A46B9/04 , A61C17/34 , A46B15/00
CPC分类号： A46D3/00 , A46B5/023 , A46B9/045 , A46B15/0097 , A61C17/3418 , A61C17/3481
摘要： A toothbrush featuring a graspable elongated handle defining a longitudinal axis, the handle comprising a neck region adjacent an end of the handle and a head disposed at the end of the handle. The head is carrying flexible bristles that extend outward from an outer surface of the head. The outer surface of the head is axisymmetric. The bristles are distributed about the head such that bristles extend in each of several radial directions, including from opposite sides of the head. At least some of the bristles are extending so as to overlay the longitudinal axis in opposite directions.
摘要翻译：一种具有限定纵向轴线的可抓握细长手柄的牙刷，所述手柄包括邻近所述手柄的端部的颈部区域和设置在所述手柄的端部处的头部。头部承载从头部的外表面向外延伸的柔性刷毛。头部的外表面是轴对称的。刷毛围绕头部分布，使得刷毛在几个径向方向中的每一个中延伸，包括从头部的相对侧。至少一些刷毛延伸以便在相反的方向上覆盖纵向轴线。

10. 发明授权

US07458242B2 Apparatus and method for manufacturing a rock bolt 失效
标题翻译：用于制造岩石锚杆的装置和方法
公开(公告)号：US07458242B2
公开(公告)日：2008-12-02
申请号：US11220254
申请日：2005-09-06
申请人： Mieczyslaw S. Rataj , Alan Henderson , Albert Taylor
发明人： Mieczyslaw S. Rataj , Alan Henderson , Albert Taylor
IPC分类号： B21B15/02 , B21D11/00 , B21D11/14 , B21F7/00
CPC分类号： B21K1/46 , B21F5/00 , B21J5/08 , D07B7/187 , E21D21/006
摘要： An apparatus for manufacturing a cable bolt from a cable (1) includes first and second clamps (2, 3) adapted to releasably clamp the cable (1) with the cable (1) extending along the longitudinal axis (4) of the apparatus. A first cable displacement device (12) longitudinally displaces the first clamp (2) relative to the second clamp (3) along the longitudinal axis (4). A first clamp rotation device (14) rotates the first clamp (2) relative to the second clamp (3) about the longitudinal axis (4). The apparatus also has a second clamp displacement device (19) for simultaneously longitudinally displacing the first and second clamps (2, 3) along the longitudinal axis (4).
摘要翻译：用于从电缆（1）制造电缆螺栓的装置包括适于可释放地夹紧电缆（1）的第一和第二夹具（2,3），其中电缆（1）沿着装置的纵向轴线（4）延伸。第一缆索位移装置（12）沿着纵向轴线（4）相对于第二夹具（3）纵向地移动第一夹具（2）。第一夹紧旋转装置（14）围绕纵向轴线（4）相对于第二夹具（3）旋转第一夹具（2）。该装置还具有用于同时沿着纵向轴线（4）纵向移位第一和第二夹具（2,3）的第二夹持位移装置（19）。

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