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1. 发明授权

US08470153B2 Cartridge and system for manipulating samples in liquid droplets 有权
标题翻译：用于操作液滴样品的墨盒和系统
公开(公告)号：US08470153B2
公开(公告)日：2013-06-25
申请号：US13188584
申请日：2011-07-22
申请人： Marc N. Feiglin , Joseph Mamone , Anne R. Kopf-Sill , Ian Fitzpatrick , Mark Rob , Phillip Duncan
发明人： Marc N. Feiglin , Joseph Mamone , Anne R. Kopf-Sill , Ian Fitzpatrick , Mark Rob , Phillip Duncan
IPC分类号： C02F1/04 , C02F11/00 , C25B9/00 , C25B11/00 , C25B13/00 , G01N27/00
CPC分类号： B01L3/502738 , B01L3/502715 , B01L3/502784 , B01L3/5029 , B01L3/523 , B01L3/527 , B01L7/52 , B01L2200/025 , B01L2200/027 , B01L2200/04 , B01L2200/0647 , B01L2200/141 , B01L2300/044 , B01L2300/0672 , B01L2300/0681 , B01L2300/0829 , B01L2300/0864 , B01L2300/0867 , B01L2300/0887 , B01L2300/089 , B01L2300/161 , B01L2400/0427 , B01L2400/043 , B01L2400/0478 , B01L2400/0638 , B01L2400/0683
摘要： A cartridge (1) comprises a working film (10) for manipulating samples in liquid droplets with an electrode array (20) when the working film (10) of the cartridge (1) is placed on said electrode array (20). The cartridge (1) comprises a body (2,2′,2″) with a number of wells (5) configured to hold therein reagents (6) or samples (6′); a flexibly deformable top structure (7) impermeable to liquids and configured to seal a top side of the wells (5); a piercable bottom structure (8) impermeable to liquids and configured to seal a bottom side of the wells (5); a working film (10) located below a lower surface (4) of the body (2,2′,2″), the working film (10) being impermeable to liquids and comprising a hydrophobic upper surface (11); a peripheral spacer (9,9′,9″) located below the lower surface (4) of the body (2,2′,2″) and connecting the working film (10) to the body (2,2′,2″); a gap (12) between the lower surface (4) of the body (2,2′,2″) and the hydrophobic upper surface (11) of the working film (10), the gap (12) being defined by the peripheral spacer (9,9′,9″); and a number of piercing elements (13) located below piercable bottom structures (8) and configured to pierce the piercable bottom structures (8) for releasing reagents or samples (6,6′) from the wells (5) into the gap (12). Also disclosed is a system (40) with an electrode array (20) onto which the cartridge (1) can be placed.
摘要翻译：当药筒（1）的工作薄膜（10）被放置在所述电极阵列（20）上时，墨盒（1）包括用于用电极阵列（20）操纵液滴样品的工作薄膜（10）。墨盒（1）包括具有多个孔（5）的主体（2,2'，2“），所述孔被配置为容纳其中的试剂（6）或样品（6'）; 柔性可变形顶部结构（7），其不透液体并且构造成密封所述孔（5）的顶侧; 不透液体并且被构造成密封井（5）的底侧的可穿透底部结构（8）; 位于主体（2,2'，2“）的下表面（4）下方的工作薄膜（10），工作薄膜（10）不透液体并包括疏水性上表面（11）; 位于主体（2,2'，2“）的下表面（4）下方的外围间隔件（9,9'，9”），并将工作膜（10）连接到主体（2,2' ，2“）; 主体（2,2'，2“）的下表面（4）与工作膜（10）的疏水性上表面（11）之间的间隙（12），间隙（12）由外围间隔物（9,9'，9“）; 以及位于穿孔底部结构（8）下面的多个穿孔元件（13），并被构造成刺穿可穿透底部结构（8），用于将试剂或样品（6,6'）从孔（5）释放到间隙（12））。还公开了一种具有电极阵列（20）的系统（40），其上可以放置盒（1）。

2. 发明申请

US20130020202A1 Cartridge and System for Manipulating Samples in Liquid Droplets 有权
标题翻译：用于操作液滴样品的墨盒和系统
公开(公告)号：US20130020202A1
公开(公告)日：2013-01-24
申请号：US13188584
申请日：2011-07-22
申请人： Marc N. FEIGLIN , Joseph Mamone , Anne R. Kopf-Sill , Ian Fitzpatrick , Mark Rob , Phillip Duncan
发明人： Marc N. FEIGLIN , Joseph Mamone , Anne R. Kopf-Sill , Ian Fitzpatrick , Mark Rob , Phillip Duncan
IPC分类号： G01N27/447 , B01D57/02
CPC分类号： B01L3/502738 , B01L3/502715 , B01L3/502784 , B01L3/5029 , B01L3/523 , B01L3/527 , B01L7/52 , B01L2200/025 , B01L2200/027 , B01L2200/04 , B01L2200/0647 , B01L2200/141 , B01L2300/044 , B01L2300/0672 , B01L2300/0681 , B01L2300/0829 , B01L2300/0864 , B01L2300/0867 , B01L2300/0887 , B01L2300/089 , B01L2300/161 , B01L2400/0427 , B01L2400/043 , B01L2400/0478 , B01L2400/0638 , B01L2400/0683
摘要： A cartridge (1) comprises a working film (10) for manipulating samples in liquid droplets with an electrode array (20) when the working film (10) of the cartridge (1) is placed on said electrode array (20). The cartridge (1) comprises a body (2,2′,2″) with a number of wells (5) configured to hold therein reagents (6) or samples (6′); a flexibly deformable top structure (7) impermeable to liquids and configured to seal a top side of the wells (5); a piercable bottom structure (8) impermeable to liquids and configured to seal a bottom side of the wells (5); a working film (10) located below a lower surface (4) of the body (2,2′,2″), the working film (10) being impermeable to liquids and comprising a hydrophobic upper surface (11); a peripheral spacer (9,9′,9″) located below the lower surface (4) of the body (2,2′,2″) and connecting the working film (10) to the body (2,2′,2″); a gap (12) between the lower surface (4) of the body (2,2′,2″) and the hydrophobic upper surface (11) of the working film (10), the gap (12) being defined by the peripheral spacer (9,9′,9″); and a number of piercing elements (13) located below piercable bottom structures (8) and configured to pierce the piercable bottom structures (8) for releasing reagents or samples (6,6′) from the wells (5) into the gap (12). Also disclosed is a system (40) with an electrode array (20) onto which the cartridge (1) can be placed.
摘要翻译：当药筒（1）的工作薄膜（10）被放置在所述电极阵列（20）上时，墨盒（1）包括用于用电极阵列（20）操纵液滴样品的工作薄膜（10）。墨盒（1）包括具有多个孔（5）的主体（2,2'，2“），其构造成容纳其中的试剂（6）或样品（6'）; 柔性可变形顶部结构（7），其不透液体并且构造成密封所述孔（5）的顶侧; 不透液体并且被构造成密封井（5）的底侧的可穿透底部结构（8）; 位于主体（2,2'，2“）的下表面（4）下方的工作薄膜（10），所述工作薄膜（10）不透液体并包括疏水性上表面（11）; 位于主体（2,2'，2“）的下表面（4）下方的外围间隔件（9,9'，9”），并将工作膜（10）连接到主体（2,2'，2“ “）; 主体（2,2'，2“）的下表面（4）与工作薄膜（10）的疏水性上表面（11）之间的间隙（12），间隙（12）由周边间隔物（9,9'，9“）; 以及位于穿孔底部结构（8）下面的多个穿孔元件（13），并被构造成刺穿可穿透底部结构（8），用于将试剂或样品（6,6'）从孔（5）释放到间隙（12））。还公开了一种具有电极阵列（20）的系统（40），其上可以放置盒（1）。

3. 发明申请

US20100284774A1 BOTTLE TRANSFER ASSEMBLY AND COMPONENTS FOR USE THEREIN 审中-公开
标题翻译：瓶装转运组件及其使用的组件
公开(公告)号：US20100284774A1
公开(公告)日：2010-11-11
申请号：US12863689
申请日：2009-01-23
申请人： Graham Robert Swallow , Geoffrey Haslehurst , Ian Fitzpatrick
发明人： Graham Robert Swallow , Geoffrey Haslehurst , Ian Fitzpatrick
IPC分类号： C03B9/447 , F16D43/208 , B65G47/90 , B65G47/52
CPC分类号： C03B9/447
摘要： Apparatus for a bottle forming machine; wherein the apparatus comprises i) a tong arm assembly for gripping a formed bottle and for transferring it from a first location to a second location through a swinging action about a shaft, and ii) a drive that drives said swinging action; characterised in that the apparatus further comprises the following: a) a release mechanism that can disengage a tong head assembly from the drive when a collision occurs; and/or b) a tensioning device that automatically maintains tension in a drive belt or chain when the assembly is in use.
摘要翻译：成瓶机设备; 其特征在于，所述装置包括：一个钳臂组件，用于夹紧成形的瓶子，并通过围绕轴的摆动作用将其从第一位置转移到第二位置，以及ii）驱动所述摆动动作的驱动器; 其特征在于，所述装置还包括以下部件：a）释放机构，当发生碰撞时，所述释放机构能够使所述钳头组件与所述驱动器脱离; 和/或b）张紧装置，当组装件在使用中时，该张紧装置自动地维持传动带或链条中的张力。

4. 发明授权

US4901574A Resilience testing 失效
标题翻译：弹性测试
公开(公告)号：US4901574A
公开(公告)日：1990-02-20
申请号：US278960
申请日：1988-12-02
申请人： Ian Fitzpatrick
发明人： Ian Fitzpatrick
IPC分类号： G01M3/24 , G01M3/26
CPC分类号： G01M3/24
摘要： This invention concerns a resilience testing gauge and a resilience testing system, which includes the gauge, suitable for testing the seal quality of partly inflated bags. This invention also concerns a method of testing the seal quality of partly inflated bags using the resilience testing gauge. The gauge employs a first (2) and a second (3) beam cantilevered from a rigid block (4). In use the rigid block (4) is vibrated and one of the beams (3) is brought into contact with the article under test. The phase responses of the two beams (2 and 3) then provide information from which the test results can be determined.
摘要翻译：本发明涉及弹性测试仪和弹性测试系统，其包括测量仪，适用于测试部分充气袋的密封质量。本发明还涉及使用弹性测试仪测试部分充气袋的密封质量的方法。仪表采用从刚性块（4）悬臂的第一（2）和第二（3）梁。在使用中，刚性块（4）振动并且其中一个梁（3）与被测试物体接触。两个光束（2和3）的相位响应然后提供可以确定测试结果的信息。

5. 发明授权

US06478567B1 Nozzle assembly for injection molding 有权
标题翻译：喷嘴组件用于注塑
公开(公告)号：US06478567B1
公开(公告)日：2002-11-12
申请号：US09610272
申请日：2000-07-06
申请人： Yosif Kushnir , Ian Fitzpatrick
发明人： Yosif Kushnir , Ian Fitzpatrick
IPC分类号： B29C4520
CPC分类号： B29C45/27 , B29C45/278
摘要： A three piece nozzle assembly for injecting molten plastic in an injection molding machine carrying out a high pressure, high volume continuous molding process to mold thin walled parts. A nozzle housing has an internally threaded dual diameter bore in one end which receives in one bore portion an externally threaded shank of a nozzle. A sleeve is threaded into the other bore portion and is tightened adjacent to a flange on the nozzle shank to lock the nozzle to the housing and prevent the pressure of the injection molding from working the nozzle loose from the housing. A gap is formed between the sleeve and nozzle shank to reduce the thermal effects.
摘要翻译：一种用于在注射成型机中注射熔融塑料的三片式喷嘴组件，其执行高压大容量连续成型工艺以模制薄壁部件。喷嘴壳体在一端具有内螺纹双直径孔，其在一个孔部分中容纳喷嘴的外螺纹柄。套筒被拧入另一个孔部分中，并且紧邻喷嘴柄上的法兰紧固以将喷嘴锁定到壳体上，并且防止注射成型的压力使喷嘴从壳体上脱离。在套筒和喷嘴柄之间形成间隙以减少热效应。

6. 发明授权

US09839920B2 Apparatus for manipulating particles using at least one chamber having an inlet and an opposed outlet 有权
公开(公告)号：US09839920B2
公开(公告)日：2017-12-12
申请号：US13499807
申请日：2010-10-06
申请人： Sunil Mehta , Tod Herman , Joe McMahon , Stephen Wilson , Ian Fitzpatrick , Timothy Craig
发明人： Sunil Mehta , Tod Herman , Joe McMahon , Stephen Wilson , Ian Fitzpatrick , Timothy Craig
IPC分类号： B04B5/04
CPC分类号： B04B5/0442 , B04B2005/0471 , B04B2005/0492
摘要： An apparatus for manipulating particles includes: a rotor rotatable at a speed about an axis, the rotor having an outer periphery and front and rear opposite sides; at least one chamber (50) mounted on the rotor, each chamber having an inlet and an outlet; an umbilical assembly rotatable about the axis; and a drive mechanism configured to rotate the umbilical assembly at about one-half the speed of the rotor. The umbilical assembly includes: a curvilinear guide tube (125) connecting to a drum at the rear side of the rotor; a flexible conduit (130) residing in the guide tube; and first and second elongate passageways (135) for each chamber extending through the conduit, wherein the first passageway is in fluid communication with the inlet of a respective chamber and the second passageway is in fluid communication with the outlet of the respective chamber. The passageways are held in a spaced-apart relationship relative to one another.

7. 发明申请

US20120270717A1 Methods, Systems and Apparatus for Manipulating Particles 有权
标题翻译：用于操作颗粒的方法，系统和装置
公开(公告)号：US20120270717A1
公开(公告)日：2012-10-25
申请号：US13499807
申请日：2010-10-06
申请人： Sunil Mehta , Tod Herman , Joe McMahon , Stephen Wilson , Ian Fitzpatrick , Timothy Craig
发明人： Sunil Mehta , Tod Herman , Joe McMahon , Stephen Wilson , Ian Fitzpatrick , Timothy Craig
IPC分类号： B04B5/04 , B01D43/00 , B04B15/00
CPC分类号： B04B5/0442 , B04B2005/0471 , B04B2005/0492
摘要： An apparatus for manipulating particles includes: a rotor rotatable at a speed about an axis, the rotor having an outer periphery and front and rear opposite sides; at least one chamber (50) mounted on the rotor, each chamber having an inlet and an outlet; an umbilical assembly rotatable about the axis; and a drive mechanism configured to rotate the umbilical assembly at about one-half the speed of the rotor. The umbilical assembly includes: a curvilinear guide tube (125) connecting to a drum at the rear side of the rotor; a flexible conduit (130) residing in the guide tube; and first and second elongate passageways (135) for each chamber extending through the conduit, wherein the first passageway is in fluid communication with the inlet of a respective chamber and the second passageway is in fluid communication with the outlet of the respective chamber. The passageways are held in a spaced-apart relationship relative to one another.
摘要翻译：一种用于操纵颗粒的装置包括：以围绕轴线的速度旋转的转子，所述转子具有外周边和前后相对侧; 安装在转子上的至少一个室（50），每个室具有入口和出口; 围绕所述轴线旋转的脐带组件; 以及驱动机构，其构造成使所述脐带组件以所述转子的大约一半的速度旋转。脐带组件包括：连接到转子后侧的鼓的曲线导管（125）; 位于引导管中的柔性导管（130）; 以及用于每个室延伸穿过导管的第一和第二细长通道（135），其中第一通道与相应室的入口流体连通，并且第二通道与相应室的出口流体连通。通道相对于彼此保持间隔开的关系。

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