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1. 发明授权

US09039724B2 Device for occluding vascular defects 有权
标题翻译：用于阻塞血管缺陷的装置
公开(公告)号：US09039724B2
公开(公告)日：2015-05-26
申请号：US12208787
申请日：2008-09-11
申请人： Kurt Amplatz , Matthew C. Heidner , Patrick Russo , Brooke Ren , Daniel O. Adams
发明人： Kurt Amplatz , Matthew C. Heidner , Patrick Russo , Brooke Ren , Daniel O. Adams
IPC分类号： A61B17/00 , A61B17/12 , A61B19/00
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12113 , A61B17/12122 , A61B17/12159 , A61B17/12163 , A61B17/12172 , A61B17/12177 , A61B90/39 , A61B2017/00575 , A61B2017/00601 , A61B2017/00606 , A61B2017/00831
摘要： A multi-layer occluder for treating a target site within the body is provided. The occluder may include first and second layers. For example, the first layer may include braided strands of metallic material, and the second layer may include braided strands of polymeric material. At least one of the first or second layers may be configured to facilitate thrombosis.
摘要翻译：提供了用于治疗身体内的靶部位的多层封堵器。封堵器可以包括第一和第二层。例如，第一层可以包括金属材料的编织线，并且第二层可以包括聚合材料的编织线。第一或第二层中的至少一个可以被配置为便于血栓形成。

2. 发明申请

US20100211046A1 MEDICAL DEVICE WITH STIFFENER WIRE FOR OCCLUDING VASCULAR DEFECTS 审中-公开
标题翻译：具有用于阻塞血管缺损的强化线的医疗装置
公开(公告)号：US20100211046A1
公开(公告)日：2010-08-19
申请号：US12372854
申请日：2009-02-18
申请人： Daniel O. Adams , Ryan Kariniemi , Brooke Ren , Matthew C. Heidner
发明人： Daniel O. Adams , Ryan Kariniemi , Brooke Ren , Matthew C. Heidner
IPC分类号： A61M25/00
摘要： Embodiments of the present invention provide devices and methods for treating various target sites. For example, one exemplary device includes a tubular structure having proximal and distal ends and at least one layer of braided material configured to facilitate thrombosis. The tubular structure includes an end section at the proximal or distal end having a cross-sectional dimension that is larger than that of an opening of the target site. The device also includes a stiffener wire coupled to the tubular structure, wherein the wire is configured to extend at least partially through the opening and facilitate securing the end section over the opening. The tubular structure and stiffener wire include respective preset, expanded configurations and are configured to be constrained to respective reduced configurations for delivery to the target site and to at least partially return to their respective preset, expanded configurations at the target site when unconstrained.
摘要翻译：本发明的实施方案提供了用于处理各种靶位点的装置和方法。例如，一个示例性装置包括管状结构，其具有近端和远端以及配置成促进血栓形成的至少一层编织材料。管状结构包括在近端或远端处的端部部分的横截面尺寸大于靶部位开口的截面尺寸。该装置还包括联接到管状结构的加强筋，其中所述线被构造成至少部分地延伸穿过所述开口并有利于将所述端部部分固定在所述开口上。管状结构和加强筋包括相应的预设的扩展构型，并且被配置为被限制为相应的减小配置，用于递送到目标位置，并且在不受约束时至少部分地返回到其目标位置处的各自预设的扩展配置。

3. 发明授权

US10702275B2 Medical device with stiffener wire for occluding vascular defects 有权
公开(公告)号：US10702275B2
公开(公告)日：2020-07-07
申请号：US12372854
申请日：2009-02-18
申请人： Daniel O. Adams , Ryan Kariniemi , Brooke Ren , Matthew C. Heidner
发明人： Daniel O. Adams , Ryan Kariniemi , Brooke Ren , Matthew C. Heidner
IPC分类号： A61B17/12 , A61B17/00 , A61M25/00
摘要： One exemplary device includes a tubular structure having proximal and distal ends and at least one layer of braided material configured to facilitate thrombosis. The tubular structure includes an end section at the proximal or distal end having a cross-sectional dimension that is larger than that of an opening of the target site. The device also includes a stiffener wire coupled to the tubular structure, and the wire is configured to extend at least partially through the opening and facilitate securing the end section over the opening. The tubular structure and stiffener wire include respective preset, expanded configurations and are configured to be constrained to respective reduced configurations for delivery to the target site and to at least partially return to their respective preset, expanded configurations at the target site when unconstrained.

4. 发明授权

US09232992B2 Multi-layered medical device for treating a target site and associated method 有权
标题翻译：用于治疗目标部位的多层医疗装置及相关方法
公开(公告)号：US09232992B2
公开(公告)日：2016-01-12
申请号：US12179157
申请日：2008-07-24
申请人： Matthew C. Heidner , Daniel O. Adams
发明人： Matthew C. Heidner , Daniel O. Adams
IPC分类号： A61F2/06 , A61B17/12 , A61F2/24 , A61B17/00 , A61F2/07
CPC分类号： A61F2/06 , A61B17/12036 , A61B17/12109 , A61B17/12118 , A61B17/12172 , A61B17/12177 , A61B2017/00526 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623 , A61B2017/00867 , A61F2/07 , A61F2/2493 , A61F2002/068
摘要： Embodiments of the present invention provide medical devices and methods for treating a target site within the body, such as for treating vascular abnormalities. For example, one embodiment provides a stent graft including an occlusive material having a preset, overlapping configuration comprising at least three inverted overlapping layers that are folded over one another. The at least three inverted overlapping layers are configured to be separated and disposed within a catheter in a non-overlapping configuration and return to the preset, overlapping configuration when deployed from the catheter.
摘要翻译：本发明的实施方案提供用于治疗体内靶点的医疗装置和方法，例如用于治疗血管异常。例如，一个实施例提供一种支架移植物，其包括具有预设的重叠构型的封闭材料，所述重叠配置包括彼此折叠的至少三个倒置的重叠层。所述至少三个倒置的重叠层被配置为以不重叠的构造分离并设置在导管内，并且当从导管展开时返回到预设的重叠构型。

5. 发明申请

US20100023046A1 MULTI-LAYERED MEDICAL DEVICE FOR TREATING A TARGET SITE AND ASSOCIATED METHOD 有权
标题翻译：用于处理目标位置的多层医疗设备及相关方法
公开(公告)号：US20100023046A1
公开(公告)日：2010-01-28
申请号：US12179157
申请日：2008-07-24
申请人： Matthew C. Heidner , Daniel O. Adams
发明人： Matthew C. Heidner , Daniel O. Adams
IPC分类号： A61M29/00
CPC分类号： A61F2/06 , A61B17/12036 , A61B17/12109 , A61B17/12118 , A61B17/12172 , A61B17/12177 , A61B2017/00526 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623 , A61B2017/00867 , A61F2/07 , A61F2/2493 , A61F2002/068
摘要： Embodiments of the present invention provide medical devices and methods for treating a target site within the body, such as for treating vascular abnormalities. For example, one embodiment provides a stent graft including an occlusive material having a preset, overlapping configuration comprising at least three inverted overlapping layers that are folded over one another. The at least three inverted overlapping layers are configured to be separated and disposed within a catheter in a non-overlapping configuration and return to the preset, overlapping configuration when deployed from the catheter.
摘要翻译：本发明的实施方案提供用于治疗体内靶点的医疗装置和方法，例如用于治疗血管异常。例如，一个实施例提供一种支架移植物，其包括具有预设的重叠构型的封闭材料，所述重叠配置包括彼此折叠的至少三个倒置的重叠层。所述至少三个倒置的重叠层被配置为以不重叠的构造分离并设置在导管内，并且当从导管展开时返回到预设的重叠构型。

6. 发明申请

US20090018562A1 Percutaneous catheter directed intravascular occlusion devices 有权
标题翻译：经皮导管导管的血管内闭塞装置
公开(公告)号：US20090018562A1
公开(公告)日：2009-01-15
申请号：US11827590
申请日：2007-07-12
申请人： Kurt Amplatz , Xiaoping Gu , John Oslund , Daniel O. Adams
发明人： Kurt Amplatz , Xiaoping Gu , John Oslund , Daniel O. Adams
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12109 , A61B17/12122 , A61B17/12172 , A61B17/12177 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00628 , A61B2017/00632 , A61B2017/00867
摘要： The present invention provides an improved vascular occlusion device having improved flexibility and retention of the type fabricated from braided tubular metal fabric having an expanded preset configuration and an elongated collapsed reduced diameter configuration for delivery through a catheter to a treatment site and shaped to create an occlusion of an abnormal opening in a body organ or vessel, the woven metal fabric having a memory property whereby the medical device tends to return to said expanded preset configuration when unconstrained. The device further including at least one disk portion adjacent a body cylindrical portion formed from the fabric and having a transition diameter between the disk and cylindrical portion, significantly smaller than the diameter of the disk and the diameter of the cylindrical portion.
摘要翻译：本发明提供了一种改进的血管闭塞装置，其具有改进的由具有扩大的预设构型的编织管状金属织物制造的类型的柔性和保持性，以及用于通过导管输送到治疗部位并且成形以产生闭塞身体器官或血管中的异常开口，织造金属织物具有记忆特性，由此医疗装置在不受约束时往往返回到所述扩展的预设构型。所述装置还包括至少一个与所述织物形成的主体圆柱形部分相邻的圆盘部分，并且在所述圆盘和圆柱形部分之间具有明显小于所述圆盘直径和所述圆柱形部分直径的过渡直径。

7. 发明申请

US20100063578A1 BIFURCATED MEDICAL DEVICE FOR TREATING A TARGET SITE AND ASSOCIATED METHOD 审中-公开
标题翻译：用于治疗目标位点和相关方法的分离式医疗装置
公开(公告)号：US20100063578A1
公开(公告)日：2010-03-11
申请号：US12205083
申请日：2008-09-05
申请人： Brooke Ren , Daniel O. Adams , John C. Oslund
发明人： Brooke Ren , Daniel O. Adams , John C. Oslund
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/848 , A61F2/90 , A61F2002/067 , A61F2210/0076 , A61F2220/0091 , A61F2230/0034 , A61F2240/001 , A61F2250/0039 , A61F2250/0067 , A61F2250/0098
摘要： Embodiments of the present invention provide medical devices and methods for treating a target site within the body. For example, one embodiment provides a stent graft for treating a target site proximate to a bifurcated lumen, wherein the stent graft includes a first tubular structure having proximal and distal ends and a side wall extending therebetween. The first tubular structure includes an opening defined within the side wall and is configured to define a first portion having first and second ends and a second portion having first and second ends. The opening corresponds to the first ends of the first and second portions and the second ends of the first and second portions respectively correspond to the proximal and distal ends of the first tubular structure, and at least a portion of the first and second portions are configured to be positioned within respective branches of a bifurcated lumen.
摘要翻译：本发明的实施例提供用于治疗身体内的靶部位的医疗装置和方法。例如，一个实施例提供了用于治疗接近分叉腔的靶部位的支架移植物，其中支架移植物包括具有近端和远端的第一管状结构和在其间延伸的侧壁。第一管状结构包括限定在侧壁内的开口，并且构造成限定具有第一和第二端部的第一部分和具有第一和第二端部的第二部分。开口对应于第一和第二部分的第一端部，第一和第二部分的第二端部分别对应于第一管状结构的近端和远端，并且第一和第二部分的至少一部分被配置定位在分叉腔的相应分支内。

8. 发明申请

US20120053615A1 RAPID EXCHANGE CATHETERS USABLE WITH EMBOLIC PROTECTION DEVICES 有权
标题翻译：快速交换电缆可用于嵌入式保护装置
公开(公告)号：US20120053615A1
公开(公告)日：2012-03-01
申请号：US13223774
申请日：2011-09-01
申请人： Daniel O. Adams , Marwane Berrada , Cathleen M. von Lehe , Richard S. Kusleika
发明人： Daniel O. Adams , Marwane Berrada , Cathleen M. von Lehe , Richard S. Kusleika
IPC分类号： A61B17/22
CPC分类号： A61F2/013 , A61F2002/011 , A61F2002/018 , A61F2230/0008 , A61F2230/008
摘要： Catheters, assemblies, and methods for delivering and recovering embolic protection devices. Catheters are provided that can be advanced over single length guide wires and which can be retracted over single length wire shafts of distal embolic protection devices. One catheter is a two-port catheter having two sidewall ports, a distal end port, and a proximal end port. The two-port catheter can be advanced over a guide wire threaded between the distal end port and the distal sidewall port. An embolic protection device wire shaft can be back loaded into the distal end port and out the proximal sidewall port. A three-port catheter includes a distal end port, and distal, intermediate, and proximal sidewall ports.
摘要翻译：用于输送和恢复栓塞保护装置的导管，组件和方法。提供导管，其可以在单长导丝上前进，并且可以在远端栓塞保护装置的单长丝线轴上缩回。一个导管是具有两个侧壁端口，远端端口和近端端口的双端口导管。双端口导管可以在远端端口和远端侧壁端口之间的引导线上前进。栓塞保护装置线轴可以被背负载到远端端口中并且从近端侧壁端口出来。三端口导管包括远端端口以及远端，中间和近端侧壁端口。

9. 发明申请

US20110283871A1 BRANCHED STENT/GRAFT AND METHOD OF FABRICATION 有权
标题翻译：分支支架/格子和制造方法
公开(公告)号：US20110283871A1
公开(公告)日：2011-11-24
申请号：US13197526
申请日：2011-08-03
申请人： Daniel O. Adams
发明人： Daniel O. Adams
IPC分类号： D04C1/00
CPC分类号： A61F2/90 , A61F2/06 , A61F2002/065 , A61F2220/0075 , A61F2230/001 , D04C1/06 , D04C3/48 , D10B2509/06
摘要： Branched braided stent or graft devices and processes for fabrication of the devices are disclosed in which a trunk portion and two hinge leg portions are fabricated in one piece braided from a single plurality of filaments, whereby the legs contain the full plurality of filaments and the trunk portion contains a subset of the same plurality of filaments. The fabrication process involves braiding the hinged legs on a mandrel while retaining loops of filament between the hinged leg portions for subsequent braiding of the trunk portion of the stent or graft.
摘要翻译：公开了分支编织支架或移植装置以及用于制造装置的方法，其中主体部分和两个铰链腿部由单个多根细丝编成一体制成，由此腿部包含完整的多根细丝，躯干部分包含相同多个细丝的子集。制造过程包括将铰链腿编织在心轴上，同时将细丝圈保持在铰链腿部之间，以便随后编织支架或移植物的躯干部分。

10. 发明申请

US20090082803A1 BRAIDED VASCULAR DEVICES HAVING NO END CLAMPS 审中-公开
标题翻译：具有无末端束的BRAIDED血管装置
公开(公告)号：US20090082803A1
公开(公告)日：2009-03-26
申请号：US11861954
申请日：2007-09-26
申请人： Daniel O. Adams , Paul Pignato
发明人： Daniel O. Adams , Paul Pignato
IPC分类号： A61B17/03
CPC分类号： A61B17/12113 , A61B17/0057 , A61B17/12022 , A61B17/12036 , A61B17/12109 , A61B17/12172 , A61B17/12177 , A61B2017/00575 , A61B2017/00615 , A61B2017/00623 , A61B2017/00867 , A61B2017/12054 , A61B2017/12095
摘要： In some embodiments, a medical device may include one or more of the following features: (a) a metal fabric formed of braided metal strands, (b) the medical device having a collapsed configuration for delivery through a channel in a patient's body and having a generally dumbbell-shaped expanded configuration with two expanded diameter portions separated by a reduced diameter portion formed between opposed ends of the device and unsecured metal strand ends at the opposed ends, and (d) a thrombogenic agent located on the metal fabric.
摘要翻译：在一些实施例中，医疗装置可以包括以下特征中的一个或多个：（a）由编织的金属线形成的金属织物，（b）医疗装置具有用于通过患者体内的通道递送的收缩构型，通常哑铃形的扩张构型具有两个扩展直径部分，该两个扩展直径部分由形成在装置的相对端部之间的直径减小的部分和在相对端处的不牢固的金属股末端分开，以及（d）位于金属织物上的血栓形成剂。

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