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1. 发明申请

US20090018562A1 Percutaneous catheter directed intravascular occlusion devices 有权
标题翻译：经皮导管导管的血管内闭塞装置
公开(公告)号：US20090018562A1
公开(公告)日：2009-01-15
申请号：US11827590
申请日：2007-07-12
申请人： Kurt Amplatz , Xiaoping Gu , John Oslund , Daniel O. Adams
发明人： Kurt Amplatz , Xiaoping Gu , John Oslund , Daniel O. Adams
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12109 , A61B17/12122 , A61B17/12172 , A61B17/12177 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00628 , A61B2017/00632 , A61B2017/00867
摘要： The present invention provides an improved vascular occlusion device having improved flexibility and retention of the type fabricated from braided tubular metal fabric having an expanded preset configuration and an elongated collapsed reduced diameter configuration for delivery through a catheter to a treatment site and shaped to create an occlusion of an abnormal opening in a body organ or vessel, the woven metal fabric having a memory property whereby the medical device tends to return to said expanded preset configuration when unconstrained. The device further including at least one disk portion adjacent a body cylindrical portion formed from the fabric and having a transition diameter between the disk and cylindrical portion, significantly smaller than the diameter of the disk and the diameter of the cylindrical portion.
摘要翻译：本发明提供了一种改进的血管闭塞装置，其具有改进的由具有扩大的预设构型的编织管状金属织物制造的类型的柔性和保持性，以及用于通过导管输送到治疗部位并且成形以产生闭塞身体器官或血管中的异常开口，织造金属织物具有记忆特性，由此医疗装置在不受约束时往往返回到所述扩展的预设构型。所述装置还包括至少一个与所述织物形成的主体圆柱形部分相邻的圆盘部分，并且在所述圆盘和圆柱形部分之间具有明显小于所述圆盘直径和所述圆柱形部分直径的过渡直径。

2. 发明授权

US08313505B2 Device for occluding vascular defects 有权
标题翻译：用于阻塞血管缺陷的装置
公开(公告)号：US08313505B2
公开(公告)日：2012-11-20
申请号：US12040260
申请日：2008-02-29
申请人： Kurt Amplatz , Matt Glimsdale , Jana Santer , Xiaoping Gu , John Oslund
发明人： Kurt Amplatz , Matt Glimsdale , Jana Santer , Xiaoping Gu , John Oslund
IPC分类号： A61F2/00
CPC分类号： A61B17/0057 , A61B17/12109 , A61B17/12122 , A61B17/12163 , A61B17/12172 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00867 , A61B2017/12127
摘要： Embodiments of the present invention provide devices and methods for treating abnormalities. For example, a device according to one embodiment includes a plurality of planes of occlusion, at least one plane of occlusion comprising a plurality of layers of occlusive material. The device is configured to at least partially occlude an abnormality.
摘要翻译：本发明的实施例提供了用于治疗异常的装置和方法。例如，根据一个实施例的装置包括多个闭塞平面，至少一个闭塞平面包括多个封闭材料层。该装置被配置为至少部分地遮挡异常。

3. 发明申请

US20080200945A1 DEVICE FOR OCCLUDING VASCULAR DEFECTS 有权
标题翻译：用于监测血管缺损的装置
公开(公告)号：US20080200945A1
公开(公告)日：2008-08-21
申请号：US12040260
申请日：2008-02-29
申请人： Kurt Amplatz , Matt Glimsdale , Jana Santer , Xiaoping Gu , John Oslund
发明人： Kurt Amplatz , Matt Glimsdale , Jana Santer , Xiaoping Gu , John Oslund
IPC分类号： A61M29/00 , A61B17/08
CPC分类号： A61B17/0057 , A61B17/12109 , A61B17/12122 , A61B17/12163 , A61B17/12172 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00867 , A61B2017/12127
摘要： Embodiments of the present invention provide devices and methods for treating abnormalities. For example, a device according to one embodiment includes a plurality of planes of occlusion, at least one plane of occlusion comprising a plurality of layers of occlusive material. The device is configured to at least partially occlude an abnormality.
摘要翻译：本发明的实施例提供了用于治疗异常的装置和方法。例如，根据一个实施例的装置包括多个闭塞平面，至少一个闭塞平面包括多个封闭材料层。该装置被配置为至少部分地遮挡异常。

4. 发明申请

US20060241690A1 Multi-layer braided structures for occluding vascular defects and for occluding fluid flow through portions of the vasculature of the body 有权
公开(公告)号：US20060241690A1
公开(公告)日：2006-10-26
申请号：US11473971
申请日：2006-06-23
申请人： Kurt Amplatz , Xiaoping Gu , John Oslund , Gary Thill
发明人： Kurt Amplatz , Xiaoping Gu , John Oslund , Gary Thill
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00867
摘要： A collapsible medical device and associated methods of occluding an abnormal opening in, for example, a body organ, wherein the medical device is shaped from plural layers of a heat-treatable metal fabric. Each of the fabric layers is formed from a plurality of metal strands and the assembly is heat-treated within a mold in order to substantially set a desired shape of the device. By incorporating plural layers in the thus-formed medical device, the ability of the device to rapidly occlude an abnormal opening in a body organ is significantly improved.

5. 发明授权

US09877710B2 Multi-layer braided structures for occluding vascular defects and for occluding fluid flow through portions of the vasculature of the body 有权
公开(公告)号：US09877710B2
公开(公告)日：2018-01-30
申请号：US13618483
申请日：2012-09-14
申请人： Kurt Amplatz , Xiaoping Gu , John C. Oslund , Gary A. Thill
发明人： Kurt Amplatz , Xiaoping Gu , John C. Oslund , Gary A. Thill
IPC分类号： A61M29/00 , A61B17/00 , A61B17/12
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00867
摘要： A collapsible medical device and associated methods of occluding an abnormal opening in, for example, a body organ, wherein the medical device is shaped from plural layers of a heat-treatable metal fabric. Each of the fabric layers is formed from a plurality of metal strands and the assembly is heat-treated within a mold in order to substantially set a desired shape of the device. By incorporating plural layers in the thus-formed medical device, the ability of the device to rapidly occlude an abnormal opening in a body organ is significantly improved.

6. 发明授权

US09743932B2 Flanged occlusion devices and methods 有权
公开(公告)号：US09743932B2
公开(公告)日：2017-08-29
申请号：US11476947
申请日：2006-06-27
申请人： Kurt Amplatz , Gary A. Thill , Pat Russo , Xiaoping Gu , Jana Santer
发明人： Kurt Amplatz , Gary A. Thill , Pat Russo , Xiaoping Gu , Jana Santer
IPC分类号： A61B17/12 , A61B17/00
CPC分类号： A61B17/12022 , A61B17/0057 , A61B17/12122 , A61B17/12172 , A61B2017/00243 , A61B2017/00575 , A61B2017/00592 , A61B2017/00615 , A61B2017/00632
摘要： Implantable occlusion devices that include one or more flanges extending from a tubular body are disclosed. The flange or flanges may assist in retention of the device within a vessel, cavity, appendage, etc. At least one flange on the occlusion device may include a concave surface proximate one end of a body. Because of the shape of the flange, e.g., its concavity, the occlusion device may resist dislocation due to e.g., the forces generated within the left atrial appendage during atrial fibrillation.

7. 发明授权

US09743918B2 Percutaneous catheter directed intravascular occlusion device 有权
公开(公告)号：US09743918B2
公开(公告)日：2017-08-29
申请号：US12235059
申请日：2008-09-22
申请人： Kurt Amplatz , Xiaoping Gu , John C. Oslund
发明人： Kurt Amplatz , Xiaoping Gu , John C. Oslund
IPC分类号： A61B17/00 , A61B90/00
CPC分类号： A61B17/0057 , A61B2017/00575 , A61B2017/00592 , A61B2017/00601 , A61B2017/00606 , A61B2017/00867 , A61B2017/00911 , A61B2090/3933
摘要： Embodiments of the present invention provide medical devices and methods for occluding a target site are provided. For example, the medical device may include a tubular member having proximal and distal ends and at least one plane of occlusion. The at least one plane of occlusion may be configured to substantially occlude the patent ductus arteriosus in less than about 1 minute. In addition or alternatively, the tubular member may consist of a single layer of material and be configured to be constrained within a catheter having an outer diameter of less than about 4 French for percutaneous delivery to the patent ductus arteriosus.

8. 发明申请

US20090210048A1 STENT/STENT GRAFT FOR REINFORCEMENT OF VASCULAR ABNORMALITIES AND ASSOCIATED METHOD 有权
标题翻译：用于加强血管异常和相关方法的STENT / STENT GRAFT
公开(公告)号：US20090210048A1
公开(公告)日：2009-08-20
申请号：US12032944
申请日：2008-02-18
申请人： Kurt Amplatz , John C. Oslund , Patrick Russo , Xiaoping Gu
发明人： Kurt Amplatz , John C. Oslund , Patrick Russo , Xiaoping Gu
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/90 , A61F2210/0076 , A61F2250/0039 , A61F2250/0063 , D04C1/02 , D04C3/48 , D10B2509/06
摘要： A stent/stent graft for reinforcement of vascular abnormalities and an associated method are provided. According to on embodiment, the stent/stent graft includes a flexible tubular structure comprising proximal and distal ends and having a heat set configuration. The tubular structure is configured to engage a lumen upstream and downstream of a vascular abnormality, such as an aneurysm, and a portion between the proximal and distal ends of the tubular structure is configured to engage the aneurysm.
摘要翻译：提供了用于增强血管异常的支架/支架移植物和相关方法。根据实施例，支架/支架移植物包括柔性管状结构，其包括近端和远端并具有热定形构型。管状结构被配置成在诸如动脉瘤的血管异常的上游和下游接合腔，并且管状结构的近端和远端之间的部分构造成与动脉瘤接合。

9. 发明授权

US08778008B2 Intravascular deliverable stent for reinforcement of vascular abnormalities 有权
标题翻译：血管内输送支架用于加强血管异常
公开(公告)号：US08778008B2
公开(公告)日：2014-07-15
申请号：US11654288
申请日：2007-01-17
申请人： Kurt Amplatz , John C. Oslund , Patrick Russo , Xiaoping Gu
发明人： Kurt Amplatz , John C. Oslund , Patrick Russo , Xiaoping Gu
IPC分类号： A61F2/06 , A61F2/82 , A61F2/852
CPC分类号： A61F2/82 , A61F2/07 , A61F2/852 , A61F2/90 , A61F2002/075 , A61F2002/823 , A61F2210/0014 , A61F2210/0076 , A61F2220/0008 , A61F2220/0041 , A61F2220/0075 , A61F2250/0015 , A61F2250/0023 , A61F2250/0037
摘要： A catheter deliverable stent/graft especially designed to be used in a minimally invasive surgical procedure for treating a variety of vascular conditions such as aneurysms, stenotic lesions and saphenous vein grafts, comprises an innermost tubular structure and at least one further tubular member in coaxial arrangement. In one embodiment, the innermost tubular structure is of a length (L1) and is formed by braiding a relatively few strands of highly elastic metallic alloy. The pick and pitch of the braid are such as to provide relative large fenestrations in the tubular wall that permit blood flow through the wall and provide the primary radial support structure. A portion of the innermost tubular structure of a length L1 is surrounded by a further braided tubular structure having relatively many strands that substantially inhibit blood flow through the fenestrations of the innermost tubular structure. The composite structure can be stretched to reduce the outer diameter of the stent/graft, allowing it to be drawn into a lumen of a delivery catheter. The catheter can then be advanced through the vascular system to the site of treatment and then released, allowing it to self-expand against the vessel wall. Various optional embodiments are disclosed that allow one skilled in the art to tailor the design to the specific application.
摘要翻译：特别设计用于治疗各种血管病变如动脉瘤，狭窄病变和隐静脉移植物的微创外科手术中的导管可输送支架/移植物包括最内管状结构和至少一个同轴布置的另外的管状构件。在一个实施例中，最内管状结构具有长度（L1），并且通过编织相对较少数量的高弹性金属合金而形成。编织物的拣选和间距是在管状壁中提供允许血液流过壁并提供初级径向支撑结构的相对较大的开窗。长度为L1的最内管状结构的一部分由具有相当多的股线的进一步的编织管状结构包围，其基本上抑制通过最内管状结构的开窗的血液流动。复合结构可被拉伸以减小支架/移植物的外径，使其能够被拉入输送导管的内腔。导管然后可以通过血管系统前进到治疗部位，然后释放，允许其自我扩张抵靠血管壁。公开了各种可选实施例，其允许本领域技术人员根据具体应用来定制设计。

10. 发明授权

US08398670B2 Multi-layer braided structures for occluding vascular defects and for occluding fluid flow through portions of the vasculature of the body 有权
标题翻译：用于阻塞血管缺陷并阻塞流体流过身体脉管系统部分的多层编织结构
公开(公告)号：US08398670B2
公开(公告)日：2013-03-19
申请号：US11473971
申请日：2006-06-23
申请人： Kurt Amplatz , Xiaoping Gu , John C. Oslund , Gary A. Thill
发明人： Kurt Amplatz , Xiaoping Gu , John C. Oslund , Gary A. Thill
IPC分类号： A61M29/00
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00867
摘要： A collapsible medical device and associated methods of occluding an abnormal opening in, for example, a body organ, wherein the medical device is shaped from plural layers of a heat-treatable metal fabric. Each of the fabric layers is formed from a plurality of metal strands and the assembly is heat-treated within a mold in order to substantially set a desired shape of the device. By incorporating plural layers in the thus-formed medical device, the ability of the device to rapidly occlude an abnormal opening in a body organ is significantly improved.
摘要翻译：一种可折叠的医疗装置和在例如身体器官中闭塞异常开口的相关方法，其中所述医疗装置由多层可热处理的金属织物成形。每个织物层由多个金属线形成，并且该组件在模具内进行热处理，以便基本上设置该装置的期望形状。通过在如此形成的医疗装置中并入多层，显着提高了装置快速闭塞体内器官的异常开口的能力。

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