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1. 发明申请

US20140108034A1 CONTINUOUS AUTOMATED HEALTHCARE ENTERPRISE RESOURCE ASSIGNMENT SYSTEM AND METHOD 审中-公开
标题翻译：连续自动化医疗保健企业资源配置系统与方法
公开(公告)号：US20140108034A1
公开(公告)日：2014-04-17
申请号：US14044326
申请日：2013-10-02
申请人： Kunter Seref Akbay , Srinivas Bollapragada , Andrew Phelps Day , Ilkin Onur Dulgeroglu , David S. Toledano , Bex George Thomas , Marcia Peterson , Dan Yang
发明人： Kunter Seref Akbay , Srinivas Bollapragada , Andrew Phelps Day , Ilkin Onur Dulgeroglu , David S. Toledano , Bex George Thomas , Marcia Peterson , Dan Yang
IPC分类号： G06Q10/06 , G06Q50/22
CPC分类号： G06Q10/06315 , G06Q50/22 , G16H40/20
摘要： Current resource data may be continuously and automatically received indicative of a current state of resources that are used to deliver healthcare to a plurality of patients associated with a healthcare enterprise. The current resource data may be automatically used to update a healthcare enterprise simulation model. The healthcare enterprise simulation model may be executed to automatically generate a predicted future state of the resources. A resource request may then be received, and a resource assignment engine may automatically assign a particular resource to the resource request based at least in part on the predicted future state of the resources.
摘要翻译：可以连续地且自动地接收当前资源数据，指示用于向与医疗保健企业相关联的多个患者提供医疗保健的资源的当前状态。可以自动使用当前资源数据来更新医疗保健企业仿真模型。可以执行医疗保健企业模拟模型以自动生成资源的预测未来状态。然后可以接收资源请求，并且资源分配引擎可以至少部分地基于资源的预测未来状态来自动地向资源请求分配特定资源。

2. 发明申请

US20140108033A1 HEALTHCARE ENTERPRISE SIMULATION MODEL INITIALIZED WITH SNAPSHOT DATA 审中-公开
标题翻译：健康企业模拟模型初始化数据
公开(公告)号：US20140108033A1
公开(公告)日：2014-04-17
申请号：US14029405
申请日：2013-09-17
申请人： Kunter Seref Akbay , Christopher Donald Johnson , Angela Neff Patterson , Andrew Phelps Day , Ilkin Onur Dulgeroglu , David S. Toledano , Bex George Thomas , Dan Yang , Peter Leigh Katlic , Marcia Peterson
发明人： Kunter Seref Akbay , Christopher Donald Johnson , Angela Neff Patterson , Andrew Phelps Day , Ilkin Onur Dulgeroglu , David S. Toledano , Bex George Thomas , Dan Yang , Peter Leigh Katlic , Marcia Peterson
IPC分类号： G06Q50/22 , G06Q10/06
CPC分类号： G06Q50/22 , G06Q10/06315 , G16H40/20
摘要： Snapshot data may be received indicative of a current state of resources that deliver healthcare to a plurality of patients associated with a healthcare enterprise. The received snapshot data may be automatically used to initialize a healthcare enterprise simulation model. The healthcare enterprise simulation model may then be executed to automatically generate a predicted future state of the resources at a predetermined point in time. Some embodiments may automatically suggest mitigation strategies based on simulated scenarios reflecting potential bottlenecks and appropriate actions that may be taken by the enterprise. The system may continuously and automatically monitor forecast accuracy to detect potential anomalies.
摘要翻译：可以接收快照数据，指示将医疗保健提供给与医疗保健企业相关联的多个患者的资源的当前状态。收到的快照数据可以自动用于初始化医疗保健企业仿真模型。然后可以执行医疗保健企业模拟模型，以在预定时间点自动生成资源的预测未来状态。一些实施例可以基于模拟的场景来自动建议缓解策略，反映出企业可能采取的潜在瓶颈和适当的行动。系统可以连续自动监测预测精度，以检测潜在的异常情况。

3. 发明授权

US11712457B2 有权
公开(公告)号：US11712457B2
公开(公告)日：2023-08-01
申请号：US17173622
申请日：2021-02-11
申请人： Qianqian Zhao , Jialin Li , Dan Yang , Jingyi Li , Liang Xin , Chunyang Shi , Xiaolin Xie , Dezhu Zhang , Ruina Bian , Xingke Ju , Chengyuan Liang , Yanjun Li , Qiao Zeng
发明人： Qianqian Zhao , Jialin Li , Dan Yang , Jingyi Li , Liang Xin , Chunyang Shi , Xiaolin Xie , Dezhu Zhang , Ruina Bian , Xingke Ju , Chengyuan Liang , Yanjun Li , Qiao Zeng
IPC分类号： A61K36/63 , A61P31/04 , A61K47/44 , A61K31/7034 , A61K31/7048
CPC分类号： A61K36/63 , A61K31/7034 , A61K31/7048 , A61K47/44 , A61P31/04 , A61K2236/15 , A61K2236/333 , A61K2236/35 , A61K2236/37 , A61K2236/51 , A61K2236/53
摘要： A Syringa microphylla seed extract includes the following components by weight based on a total weight of the Syringa microphylla seed extract: 0.4944-0.7142 mg/g of echinacoside, 6.624-7.617 mg/g of oleuropein, 0.4276-0.6309 mg/g of verbascoside, 3.927-4.684 mg/g of syringin, and 4.505-5.250 mg/g of forsythiaside B. A method of preparing the Syringa microphylla seed extract is disclosed. A composition for treating antibiotic-resistant infections that includes the Syringa microphylla seed extract is also disclosed.

4. 发明授权

US11512049B2 Pleuromutilin 2-[(diphenylmethyl)thio] acetic acid ester with anti-drug resistant bacteria activity and a method of preparing the same 有权
公开(公告)号：US11512049B2
公开(公告)日：2022-11-29
申请号：US17239582
申请日：2021-04-24
申请人： Qianqian Zhao , Yuqing Zhao , Dan Yang , Jingyi Li , Liang Xin , Ruina Bian , Jie Zhang , Han Li , Bin Tian , Yongbo Wang , Chengyuan Liang , Liang Qi , Gennian Mao
发明人： Qianqian Zhao , Yuqing Zhao , Dan Yang , Jingyi Li , Liang Xin , Ruina Bian , Jie Zhang , Han Li , Bin Tian , Yongbo Wang , Chengyuan Liang , Liang Qi , Gennian Mao
IPC分类号： C07C323/52 , A61P31/04 , C07C319/28
摘要： A compound with anti-drug resistant bacteria activity having the formula (I): (I) is disclosed. The methods of preparing the compound of formula (I) are also disclosed.

5. 发明授权

US11484598B1 Pleuromulin rhein ester with anti-drug resistant bacteria activity and a method of preparing the same 有权
公开(公告)号：US11484598B1
公开(公告)日：2022-11-01
申请号：US17460267
申请日：2021-08-29
申请人： Jia Wan , Chunchun Kong , Jingyi Li , Qianqian Zhao , Dan Yang
发明人： Jia Wan , Chunchun Kong , Jingyi Li , Qianqian Zhao , Dan Yang
IPC分类号： A61K47/55 , C07C69/94 , C07C67/14
摘要： A compound with anti-drug resistant bacteria activity having the following formula is disclosed. A method of preparing the compound of formula (I) is also disclosed.

6. 发明授权

US11306076B2 Silibinin lipoic acid ester with hepatoprotective activity and a method of preparing the same 有权
公开(公告)号：US11306076B2
公开(公告)日：2022-04-19
申请号：US16871354
申请日：2020-05-11
申请人： Yonghong Tang , Huafeng Qi , Peiyu Zhou , Xingke Ju , Chengyuan Liang , Yuzhi Liu , Bin Tian , Lei Tian , Gennian Mao , Limei Wang , Yuanyuan He , Yongbo Wang , Jingwen Xu , Dan Yang , Liang Qi , Wenbo Yao , Qianqian Zhao , Han Li
发明人： Yonghong Tang , Huafeng Qi , Peiyu Zhou , Xingke Ju , Chengyuan Liang , Yuzhi Liu , Bin Tian , Lei Tian , Gennian Mao , Limei Wang , Yuanyuan He , Yongbo Wang , Jingwen Xu , Dan Yang , Liang Qi , Wenbo Yao , Qianqian Zhao , Han Li
IPC分类号： C07D409/14 , B01J27/24
摘要： A compound having the formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.

7. 发明授权

US10729675B2 Gossypol isatin schiff base compounds with antitumor activities and a method of preparing the same 有权
公开(公告)号：US10729675B2
公开(公告)日：2020-08-04
申请号：US16270567
申请日：2019-02-07
申请人： Chengyuan Liang , Xingke Ju , Shunjun Ding , Lei Tian , Yuzhi Liu , Xiaolin Xie , Dezhu Zhang , Wenbo Yao , Dan Yang
发明人： Chengyuan Liang , Xingke Ju , Shunjun Ding , Lei Tian , Yuzhi Liu , Xiaolin Xie , Dezhu Zhang , Wenbo Yao , Dan Yang
IPC分类号： A61K31/404 , A61P35/00 , G01N33/50
摘要： A gossypol isatin Schiff base compound with antitumor activities represented by formula I: R1 and R2 are independently hydrogen, alkyl, cycloalkyl, alkoxy, nitro, halogen, unsubstituted or substituted phenyl, or unsubstituted or substituted benzyl. A method of preparing the compound of formula I is also disclosed.

8. 发明授权

US08823126B2 Low cost backside illuminated CMOS image sensor package with high integration 有权
标题翻译：低成本背照式CMOS图像传感器封装，集成度高
公开(公告)号：US08823126B2
公开(公告)日：2014-09-02
申请号：US13464939
申请日：2012-05-04
申请人： Dan Yang , Yat Kit Tsui , Shu Kin Yau , Pui Chung Law
发明人： Dan Yang , Yat Kit Tsui , Shu Kin Yau , Pui Chung Law
IPC分类号： H01L27/146
CPC分类号： H01L27/1464 , H01L27/14618 , H01L27/14627 , H01L27/14632 , H01L27/14687 , H01L2924/0002 , H01L2924/00
摘要： This invention discloses a backside illuminated image sensor without the need to involve a mechanical grinding process or a chemical-mechanical planarization process in fabrication, and a fabricating method thereof. In one embodiment, an image sensor comprises a semiconductor substrate, a plurality of light sensing elements in the semiconductor substrate, and a cavity formed in the semiconductor substrate. The light sensing elements are arranged in a substantially planar manner. The cavity has a base surface overlying the light sensing elements. The presence of the cavity allows the image to reach the light sensing elements through the cavity base surface. The cavity can be fabricated by etching the semiconductor substrate. Agitation may also be used when carrying out the etching.
摘要翻译：本发明公开了一种背面照明图像传感器，其制造方法不需要涉及机械研磨工艺或化学机械平面化工艺。在一个实施例中，图像传感器包括半导体衬底，半导体衬底中的多个感光元件和形成在半导体衬底中的空腔。光感测元件以基本上平面的方式布置。空腔具有覆盖光敏元件的基面。空腔的存在允许图像通过空腔基面到达光感测元件。可以通过蚀刻半导体衬底来制造空腔。进行蚀刻时也可以使用搅拌。

9. 发明授权

US08299067B2 5-demethoxyfumagillol and derivatives thereof 有权
标题翻译： 5-脱甲氧基烟曲霉及其衍生物
公开(公告)号：US08299067B2
公开(公告)日：2012-10-30
申请号：US12410473
申请日：2009-03-25
申请人： Dan Yang , Chengyong Li , Shiwu Chen
发明人： Dan Yang , Chengyong Li , Shiwu Chen
IPC分类号： A61K31/535 , A61K31/497 , A61K31/445 , C07D413/00 , C07D405/00 , C07D401/00 , C07D205/00 , C07D303/00
CPC分类号： C07D303/16 , C07D339/08
摘要： Provided herein are 5-demethoxyfumagillol and its derivatives. Also provided herein are methods of making the 5-demethoxyfumagillol and derivatives. Also provided herein are biological activities of the 5-demethoxyfumagillol and derivatives and methods of using same for treating diseases.
摘要翻译：本文提供5-脱甲氧基烟曲霉及其衍生物。本文还提供制备5-去甲氧基烟曲霉及其衍生物的方法。本文还提供了5-去甲氧基烟曲霉素及其衍生物的生物活性及其用于治疗疾病的方法。

10. 发明授权

US08232626B2 Via and method of via forming and method of via filling 有权
标题翻译：通孔形成方法和通孔填充方法
公开(公告)号：US08232626B2
公开(公告)日：2012-07-31
申请号：US12814938
申请日：2010-06-14
申请人： Yat Kit Tsui , Dan Yang , Xunqing Shi
发明人： Yat Kit Tsui , Dan Yang , Xunqing Shi
IPC分类号： H01L29/40 , H01L21/44 , H05K1/11
CPC分类号： H01L21/76898 , H01L23/481 , H01L2224/16145 , H01L2924/1461 , H01L2924/00
摘要： An electronic or micromechanical device having first (11) and second (12) surfaces and a via extending through the device from the first surface to the second surface. The via comprises integrally formed first (84, 86), second (82) and third (88) portions. The first portion (84, 86) extends from the first surface (11) to the second surface (12). The second portion (82) extends over a part of the first surface (11) of the device. The third portion (88) extends over a part of the second surface (12) of the device. Preferably the first portion comprises first and second parts, the second part extending through an active region of the device and having a narrower width than the first part. A method of forming and filling the via is also disclosed.
摘要翻译：具有第一表面（11）和第二表面（12）的电子或微机械装置以及从第一表面延伸穿过该装置到第二表面的通孔。通孔包括一体形成的第一（84,86），第二（82）和第三（88）部分。第一部分（84,86）从第一表面（11）延伸到第二表面（12）。第二部分（82）在装置的第一表面（11）的一部分上延伸。第三部分（88）在装置的第二表面（12）的一部分上延伸。优选地，第一部分包括第一部分和第二部分，第二部分延伸穿过装置的有源区域并且具有比第一部分更窄的宽度。还公开了形成和填充通孔的方法。

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