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    • 7. 发明授权
    • Process for producing high 2-O-&agr;-D-glucopyranosyl-L-ascorbic acid
    • 生产高2-O-α-D-吡喃葡萄糖基-L-抗坏血酸的方法
    • US06576446B2
    • 2003-06-10
    • US09875963
    • 2001-06-08
    • Hiroshi YamasakiKoichi NishiToshio Miyake
    • Hiroshi YamasakiKoichi NishiToshio Miyake
    • C12P1944
    • C07H17/04
    • Disclosed is a process for producing a high &agr;G-AA content product, which comprises the steps of: contacting a solution as a material solution, containing &agr;G-AA, L-ascorbic acid, and a saccharide(s), with an anion exchange resin packed in a column to adsorb the &agr;G-AA and L-ascorbic acid on the anion exchanger; washing the anion exchanger with water to remove the saccharide(s) therefrom; feeding to the column an aqueous solution, as an eluent, of an acid and/or a salt with a concentration of less than 0.5 N to fractionate a fraction rich in 2-O-&agr;-D-glucopyranosyl-L-ascorbic acid and a fraction rich in L-ascorbic acid; and collecting the former fraction.
    • 公开了一种制备高αG-AA含量产物的方法,其包括以下步骤:使含有αG-AA,L-抗坏血酸和糖的溶液与阴离子交换树脂接触 填充在柱中以吸附阴离子交换剂上的αG-AA和L-抗坏血酸; 用水洗涤阴离子交换剂以除去其中的糖类; 向柱中加入浓度小于0.5N的酸和/或盐的水溶液作为洗脱剂,以分级富含2-O-α-D-吡喃葡萄糖基-L-抗坏血酸的级分和 级分富含L-抗坏血酸; 并收集前一部分。