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    • 1. 发明授权
    • Method for fabricating a biosensor chip and the biosensor chip made thereby
    • 制造生物传感器芯片的方法和由此制造的生物传感器芯片
    • US08663554B2
    • 2014-03-04
    • US12858959
    • 2010-08-18
    • Kuan-Jiuh LinChuen-Yuan Hsu
    • Kuan-Jiuh LinChuen-Yuan Hsu
    • A61L2/00G01N33/553
    • G01N33/53B82Y5/00B82Y15/00
    • A method of fabricating a biosensor chip includes: forming at least one metallic layer on a transparent substrate to form a composite member; disposing the composite member in a vacuumed chamber, and introducing a gas into the vacuumed chamber; applying microwave energy to the gas to produce a microwave plasma of the gas within the vacuumed chamber, and causing the microwave plasma to interact with the metallic layer so that the metallic layer is melted and formed into a plurality of metallic nanoparticles that are spaced apart from each other and that expose partially the surface of the transparent substrate; and disposing a receptor at the surface of the transparent substrate that is exposed among the metallic nanoparticles. A biosensor chip is also disclosed.
    • 制造生物传感器芯片的方法包括:在透明基板上形成至少一层金属层以形成复合构件; 将复合构件设置在真空室中,并将气体引入真空室中; 向气体施加微波能量以在真空室内产生气体的微波等离子体,并使微波等离子体与金属层相互作用,使得金属层熔化并形成多个金属纳米颗粒,其与 并且部分地暴露在透明基板的表面上; 以及在所述金属纳米粒子中露出的所述透明基板的表面设置受体。 还公开了生物传感器芯片。
    • 4. 发明授权
    • Method for fabricating a biosensor chip and the biosensor chip made thereby
    • 制造生物传感器芯片的方法和由此制造的生物传感器芯片
    • US09091683B2
    • 2015-07-28
    • US13854847
    • 2013-04-01
    • Kuan-Jiuh LinChuen-Yuan Hsu
    • Kuan-Jiuh LinChuen-Yuan Hsu
    • G01N33/53B82Y5/00B82Y15/00
    • G01N33/53B82Y5/00B82Y15/00
    • A method of fabricating a biosensor chip includes: forming at least one metallic layer on a transparent substrate to form a composite member; disposing the composite member in a vacuumed chamber, and introducing a gas into the vacuumed chamber; applying microwave energy to the gas to produce a microwave plasma of the gas within the vacuumed chamber, and causing the microwave plasma to interact with the metallic layer so that the metallic layer is melted and formed into a plurality of metallic nanoparticles that are spaced apart from each other and that expose partially the surface of the transparent substrate; and disposing a receptor at the surface of the transparent substrate that is exposed among the metallic nanoparticles. A biosensor chip is also disclosed.
    • 制造生物传感器芯片的方法包括:在透明基板上形成至少一层金属层以形成复合构件; 将复合构件设置在真空室中,并将气体引入真空室中; 向气体施加微波能量以在真空室内产生气体的微波等离子体,并使微波等离子体与金属层相互作用,使得金属层熔化并形成多个金属纳米颗粒,其与 并且部分地暴露在透明基板的表面上; 以及在所述金属纳米粒子中露出的所述透明基板的表面设置受体。 还公开了生物传感器芯片。
    • 5. 发明申请
    • METHOD FOR FABRICATING A BIOSENSOR CHIP AND THE BIOSENSOR CHIP MADE THEREBY
    • 制造生物传感器芯片的方法和生物传感器芯片
    • US20130230427A1
    • 2013-09-05
    • US13854847
    • 2013-04-01
    • Kuan-Jiuh LinChuen-Yuan Hsu
    • Kuan-Jiuh LinChuen-Yuan Hsu
    • G01N33/53
    • G01N33/53B82Y5/00B82Y15/00
    • A method of fabricating a biosensor chip includes: forming at least one metallic layer on a transparent substrate to form a composite member; disposing the composite member in a vacuumed chamber, and introducing a gas into the vacuumed chamber; applying microwave energy to the gas to produce a microwave plasma of the gas within the vacuumed chamber, and causing the microwave plasma to interact with the metallic layer so that the metallic layer is melted and formed into a plurality of metallic nanoparticles that are spaced apart from each other and that expose partially the surface of the transparent substrate; and disposing a receptor at the surface of the transparent substrate that is exposed among the metallic nanoparticles. A biosensor chip is also disclosed.
    • 制造生物传感器芯片的方法包括:在透明基板上形成至少一层金属层以形成复合构件; 将复合构件设置在真空室中,并将气体引入真空室中; 向气体施加微波能量以在真空室内产生气体的微波等离子体,并使微波等离子体与金属层相互作用,使得金属层熔化并形成多个金属纳米颗粒,其与 并且部分地暴露在透明基板的表面上; 以及在所述金属纳米粒子中露出的所述透明基板的表面设置受体。 还公开了生物传感器芯片。
    • 7. 发明授权
    • Microwave plasma generator
    • 微波等离子发生器
    • US07714248B2
    • 2010-05-11
    • US11439742
    • 2006-05-24
    • Kuan-Jiuh LinJun-Wei SuChuen-Yuan Hsu
    • Kuan-Jiuh LinJun-Wei SuChuen-Yuan Hsu
    • B23K10/00
    • H01J37/3233H01J37/32192
    • The present invention discloses a microwave plasma generator which includes a chamber, a conductive inorganic substance, a trace gas and a microwave source. The conductive inorganic substance and the trace gas are housed in the chamber with an inner pressure about 0.001˜10 torr. By irradiating the conductive inorganic substance and exciting the trace gas, clean and uniform plasma will be generated. The plasma generator of this invention is easily operated and can be applied to semiconductor manufacturing processes, for example, material modification, etching/cleaning, roughing and ion doping/hybrid.
    • 本发明公开了一种微波等离子体发生器,其包括室,导电无机物质,痕量气体和微波源。 导电无机物质和痕量气体以约0.001〜10乇的内压收容在室内。 通过照射导电性无机物质和激发痕量气体,将产生清洁均匀的等离子体。 本发明的等离子体发生器易于操作,并且可以应用于半导体制造工艺,例如材料改性,蚀刻/清洁,粗加工和离子掺杂/混合。
    • 10. 发明申请
    • METHOD FOR FABRICATING A BIOSENSOR CHIP AND THE BIOSENSOR CHIP MADE THEREBY
    • 制造生物传感器芯片的方法和生物传感器芯片
    • US20110044857A1
    • 2011-02-24
    • US12858959
    • 2010-08-18
    • Kuan-Jiuh LinChuen-Yuan Hsu
    • Kuan-Jiuh LinChuen-Yuan Hsu
    • G01N30/00G01N1/31
    • G01N33/53B82Y5/00B82Y15/00
    • A method of fabricating a biosensor chip includes: forming at least one metallic layer on a transparent substrate to form a composite member; disposing the composite member in a vacuumed chamber, and introducing a gas into the vacuumed chamber; applying microwave energy to the gas to produce a microwave plasma of the gas within the vacuumed chamber, and causing the microwave plasma to interact with the metallic layer so that the metallic layer is melted and formed into a plurality of metallic nanoparticles that are spaced apart from each other and that expose partially the surface of the transparent substrate; and disposing a receptor at the surface of the transparent substrate that is exposed among the metallic nanoparticles. A biosensor chip is also disclosed.
    • 制造生物传感器芯片的方法包括:在透明基板上形成至少一层金属层以形成复合构件; 将复合构件设置在真空室中,并将气体引入真空室中; 向气体施加微波能量以在真空室内产生气体的微波等离子体,并使微波等离子体与金属层相互作用,使得金属层熔化并形成多个金属纳米颗粒,其与 并且部分地暴露在透明基板的表面上; 以及在所述金属纳米粒子中露出的所述透明基板的表面设置受体。 还公开了生物传感器芯片。