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1. 发明申请

US20110192217A1 Flow Distribution Mixer 有权
标题翻译：流量分配搅拌机
公开(公告)号：US20110192217A1
公开(公告)日：2011-08-11
申请号：US12702147
申请日：2010-02-08
申请人： Konstantin Choikhet , Klaus Witt , Martin Baeuerle
发明人： Konstantin Choikhet , Klaus Witt , Martin Baeuerle
IPC分类号： G01N30/84 , G01N1/28 , B01F15/02 , B01D15/08
CPC分类号： G01N30/34 , B01F5/064 , B01F5/0646 , B01F5/0647 , B01F13/0059 , G01N2030/347
摘要： A mixer for mixing a fluid having a property varying along a flow direction of the fluid includes an inlet configured for receiving an inlet flow, an outlet configured for providing an outlet flow, and a plurality of flow channels coupled between the inlet and the outlet. The mixer also includes a flow distributor for distributing the inlet flow into the plurality of flow channels so that each flow channel receives a partial flow from the inlet flow, and a flow combiner for combining the partial flows from the plurality of flow channels to the outlet flow. Each flow channel has a first flow section having a hydraulic resistance substantially representing a hydraulic resistance of the flow channel. One or more of the flow channels each have a second flow section coupled in series with the first flow section of the respective flow channel.
摘要翻译：用于混合具有沿着流体的流动方向变化的性质的流体的混合器包括构造成用于接收入口流的入口，被配置为提供出口流的出口以及耦合在入口和出口之间的多个流动通道。混合器还包括用于将入口流分配到多个流动通道中的流量分配器，使得每个流动通道接收来自入口流的部分流动，以及流动组合器，用于将来自多个流动通道的部分流合并到出口流。每个流动通道具有第一流动部分，其具有基本上表示流动通道的液压阻力的液压阻力。一个或多个流动通道各自具有与相应流动通道的第一流动部分串联联接的第二流动部分。

2. 发明授权

US08511889B2 Flow distribution mixer 有权
标题翻译：流量分配搅拌机
公开(公告)号：US08511889B2
公开(公告)日：2013-08-20
申请号：US12702147
申请日：2010-02-08
申请人： Konstantin Choikhet , Klaus Witt , Martin Baeuerle
发明人： Konstantin Choikhet , Klaus Witt , Martin Baeuerle
IPC分类号： B01F5/06
CPC分类号： G01N30/34 , B01F5/064 , B01F5/0646 , B01F5/0647 , B01F13/0059 , G01N2030/347
摘要： A mixer for mixing a fluid having a property varying along a flow direction of the fluid includes an inlet configured for receiving an inlet flow, an outlet configured for providing an outlet flow, and a plurality of flow channels coupled between the inlet and the outlet. The mixer also includes a flow distributor for distributing the inlet flow into the plurality of flow channels so that each flow channel receives a partial flow from the inlet flow, and a flow combiner for combining the partial flows from the plurality of flow channels to the outlet flow. Each flow channel has a first flow section having a hydraulic resistance substantially representing a hydraulic resistance of the flow channel. One or more of the flow channels each have a second flow section coupled in series with the first flow section of the respective flow channel.
摘要翻译：用于混合具有沿着流体的流动方向变化的性质的流体的混合器包括构造成用于接收入口流的入口，被配置为提供出口流的出口以及耦合在入口和出口之间的多个流动通道。混合器还包括用于将入口流分配到多个流动通道中的流量分配器，使得每个流动通道接收来自入口流的部分流动，以及流动组合器，用于将来自多个流动通道的部分流合并到出口流。每个流动通道具有第一流动部分，其具有基本上表示流动通道的液压阻力的液压阻力。一个或多个流动通道各自具有与相应流动通道的第一流动部分串联联接的第二流动部分。

3. 发明申请

US20110023976A1 FLUIDIC DEVICE WITH PLANAR COUPLING MEMBER 审中-公开
标题翻译：具有平面耦合构件的流体装置
公开(公告)号：US20110023976A1
公开(公告)日：2011-02-03
申请号：US12935911
申请日：2008-04-03
申请人： Martin Baeuerle , Jochen Mueller , Konstantin Choikhet , Klaus Witt
发明人： Martin Baeuerle , Jochen Mueller , Konstantin Choikhet , Klaus Witt
IPC分类号： F15C5/00 , B23K31/02
CPC分类号： G01N30/6004 , B01J2219/00804 , B01J2219/0081 , B01L3/502707 , B01L3/502715 , B01L3/565 , B01L3/567 , B01L2200/025 , B01L2200/027 , B01L2300/0887 , B01L2400/0622 , G01N30/6095 , Y10T137/0491 , Y10T137/86863
摘要： A fluidic device for providing fluidic connections is described. The fluidic device comprises a fluid conduit and a planar coupling member with a fluid port, the fluid port being fluidically connected with the fluid conduit. A contour of the planar coupling member is in a predefined relationship with the fluid port's position.
摘要翻译：描述了用于提供流体连接的流体装置。流体装置包括流体导管和具有流体端口的平面连接构件，流体端口与流体导管流体连接。平面耦合构件的轮廓与流体端口的位置成预定关系。

4. 发明申请

US20070116609A1 Microfluidic arrangement for microfluidic optical detection 审中-公开
标题翻译：用于微流体光学检测的微流体排列
公开(公告)号：US20070116609A1
公开(公告)日：2007-05-24
申请号：US11654210
申请日：2007-01-17
申请人： Martin Baeuerle , Hans-Peter Zimmermann , Konstantin Choikhet , Tobias Preckel
发明人： Martin Baeuerle , Hans-Peter Zimmermann , Konstantin Choikhet , Tobias Preckel
IPC分类号： B01L3/02
CPC分类号： G01N30/74 , B01L3/502715 , B01L9/527 , B01L2200/027 , B01L2300/0654 , B01L2300/0877 , B01L2300/168 , G01N21/05 , G01N2021/0346 , G01N2030/746 , G01N30/6095
摘要： A microfluidic arrangement (1) for the optical detection of fluids is provided, comprising a microfluidic device (2) having at least one first channel (3) with an opening (4) which is in fluid communication with an optical detection unit (6) of an optical device (5); the microfluidic device (2) being operatively detachably coupled with the optical device (5) whereby an extension of the part (7,7′) of relevance of the optical detection path (17) is provided. A method for detecting fluids using the arrangement of the present invention is provided.
摘要翻译：提供了一种用于流体光学检测的微流体装置（1），包括具有至少一个具有与光学检测单元（6）流体连通的开口（4）的至少一个第一通道（3）的微流体装置（2）的光学装置（5）; 所述微流体装置（2）可操作地与所述光学装置（5）耦合，由此提供所述光学检测路径（17）的相关部分（7,7'）的延伸。提供了使用本发明的装置检测流体的方法。

5. 发明授权

US08641267B2 Fluidic conduit with repeated disturbance of laminar flow 有权
标题翻译：具有反复层流紊流的流体导管
公开(公告)号：US08641267B2
公开(公告)日：2014-02-04
申请号：US12102444
申请日：2008-04-14
申请人： Martin Baeuerle , Konstantin Choikhet
发明人： Martin Baeuerle , Konstantin Choikhet
IPC分类号： B01F5/06
CPC分类号： B01F5/061 , B01F5/0646 , B01F5/0647 , B01F5/065 , B01F2005/0621 , B01F2005/0636 , G01N30/6086 , G01N30/6095 , Y10T137/87619 , Y10T137/87652
摘要： A fluidic device, the fluidic device comprising a planar fluidic conduit for conducting a fluid, wherein the fluidic conduit has a plurality of fluidic disturbance features located along at least a section of the fluidic conduit for disturbing a laminar flow of the fluid along the section.
摘要翻译：一种流体装置，流体装置包括用于传导流体的平面流体导管，其中流体导管具有沿着流体导管的至少一部分定位的多个流体扰动特征，用于干扰流体沿该部分的层流。

6. 发明授权

US09671375B2 Fluidic chip with displacable patterned layer for detecting fluid pressure 有权
公开(公告)号：US09671375B2
公开(公告)日：2017-06-06
申请号：US14344113
申请日：2011-09-15
申请人： Martin Baeuerle , Konstantin Choikhet
发明人： Martin Baeuerle , Konstantin Choikhet
IPC分类号： G01N30/32 , B01L3/00 , B01D15/10 , B01D53/02 , B01D57/02 , G01L13/02 , G01L13/06 , G01L27/00 , G01N30/36 , G01N30/60
CPC分类号： G01N30/32 , B01D15/10 , B01D53/025 , B01D57/02 , B01L3/5027 , B01L2200/146 , B01L2300/0663 , B01L2300/0816 , B01L2300/14 , B01L2400/0487 , G01L13/023 , G01L13/06 , G01L27/002 , G01N30/36 , G01N30/6095 , G01N2030/326
摘要： A fluidic chip device configured for processing a fluid, wherein the fluidic chip device comprises a plurality of layers laminated to one another, wherein at least a part of the layers comprises a patterned section of an alternating sequence of bars and fluidic channels for conducting the fluid under pressure, the patterned section being configured for being displaceable in response to the pressure, and a pressure detector responding to the displacement of the patterned section by generating a detector signal being indicative of a value of the pressure.

7. 发明申请

US20150000416A1 Fluidic Chip with Displacable Patterned Layer for Detecting Fluid Pressure 有权
标题翻译：具有可拆卸图案层的流体芯片，用于检测流体压力
公开(公告)号：US20150000416A1
公开(公告)日：2015-01-01
申请号：US14344113
申请日：2011-09-15
申请人： Martin Baeuerle , Konstantin Choikhet
发明人： Martin Baeuerle , Konstantin Choikhet
IPC分类号： G01N30/32 , B01D53/02 , G01N30/36 , G01L13/02 , G01L13/06 , G01L27/00 , B01D15/10 , B01D57/02
CPC分类号： G01N30/32 , B01D15/10 , B01D53/025 , B01D57/02 , B01L3/5027 , B01L2200/146 , B01L2300/0663 , B01L2300/0816 , B01L2300/14 , B01L2400/0487 , G01L13/023 , G01L13/06 , G01L27/002 , G01N30/36 , G01N30/6095 , G01N2030/326
摘要： A fluidic chip device configured for processing a fluid, wherein the fluidic chip device comprises a plurality of layers laminated to one another, wherein at least a part of the layers comprises a patterned section of an alternating sequence of bars and fluidic channels for conducting the fluid under pressure, the patterned section being configured for being displaceable in response to the pressure, and a pressure detector responding to the displacement of the patterned section by generating a detector signal being indicative of a value of the pressure.
摘要翻译：一种构造成用于处理流体的流体芯片装置，其中所述流体芯片装置包括彼此层叠的多个层，其中所述层的至少一部分包括用于传导流体的条和流体通道的交替序列的图案化部分在压力下，图案化部分被配置为响应于压力而移动;以及压力检测器，通过产生指示压力值的检测器信号来响应于图案化部分的位移。

8. 发明授权

US09694301B2 Two-dimensional fluid separation with controlled pressure 有权
公开(公告)号：US09694301B2
公开(公告)日：2017-07-04
申请号：US14400312
申请日：2012-05-10
申请人： Konstantin Choikhet , Klaus Witt
发明人： Konstantin Choikhet , Klaus Witt
IPC分类号： B01D15/18 , G01N30/32 , G01N30/46 , G01N27/447 , G01N30/72 , G01N30/34 , G01N30/60
CPC分类号： B01D15/18 , G01N27/44704 , G01N30/32 , G01N30/34 , G01N30/463 , G01N30/465 , G01N30/6095 , G01N30/72 , G01N2030/322 , G01N2030/328
摘要： A sample separation apparatus for separating a liquid sample includes a first separation unit for separating the sample, a first fluid drive for conducting the sample to be separated through the first separation unit, a second separation unit, arranged downstream of the first separation unit, for further separating the sample, a second fluid drive for at least partially conducting the sample through the second separation unit, and a fluidic valve having interfaces fluidically coupled to the first and second fluid drives and being switchable for performing the separation of the sample. The apparatus is configured for adjusting a pressure at a predefined position to a predefined value, wherein the predefined position is in a fluidic path between an outlet of the first separation unit and an inlet of the second separation unit or in fluid communication with this fluidic path.

9. 发明申请

US20150059451A1 PREVENTION OF PHASE SEPARATION UPON PROPORTIONING AND MIXING FLUIDS 有权
标题翻译：防止相分离和混合液相分离
公开(公告)号：US20150059451A1
公开(公告)日：2015-03-05
申请号：US14396938
申请日：2012-04-25
申请人： Klaus Witt , Konstantin Choikhet
发明人： Klaus Witt , Konstantin Choikhet
IPC分类号： B01D15/12 , G01N30/16
CPC分类号： B01D15/12 , B01L3/502784 , B01L2200/0673 , B01L2400/0487 , B01L2400/0644 , G01N30/16 , G01N30/34
摘要： A fluid supply system (150) configured for supplying fluids, the fluid supply system (150) comprising a fluid packet supply unit (180) configured for controlling supply of a sequence (250) of fluid packets (222 to 230), the fluid packets (222 to 230) comprising a packet of first fluid (223) and a packet of second fluid (225), wherein the first fluid and the second fluid are media being prone to a phase separation upon direct interaction between the packet of first fluid (223) and the packet of second fluid (225), and a phase separation inhibiting unit (190) configured for inhibiting phase separation by inserting an intermediate fluid packet (224) between the packet of first fluid (223) and the packet of second fluid (225) to 230 to 230
摘要翻译：一种构造成供应流体的流体供应系统（150），所述流体供应系统（150）包括被配置为控制流体包（222至230）的序列（250）的供应的流体包供应单元（180），所述流体包（222至230），包括第一流体（223）和第二流体（225）的包装，其中所述第一流体和所述第二流体是介质在所述第一流体包之间的直接相互作用时易于相分离 223）和第二流体（225）的分组，以及相分离禁止单元（190），其被配置为通过在第一流体（223）的包和第二流体包之间插入中间流体包（224）来抑制相分离（225）至230至230

10. 发明申请

US20120198919A1 LIQUID SUPPLY WITH OPTIMIZED SWITCHING BETWEEN DIFFERENT SOLVENTS 审中-公开
标题翻译：液体供应与不同溶剂之间的优化切换
公开(公告)号：US20120198919A1
公开(公告)日：2012-08-09
申请号：US13346092
申请日：2012-01-09
申请人： Klaus Witt , Konstantin Choikhet , Philip Herzog
发明人： Klaus Witt , Konstantin Choikhet , Philip Herzog
IPC分类号： G01N11/00
CPC分类号： G01N30/34
摘要： A method for metering two or more liquids in controlled proportions in a liquid supply system and for supplying a resultant mixture, in which the liquid supply system includes a plurality of solvent supply lines, a proportioning valve interposed between the solvent supply lines and an inlet of a pumping unit, the method includes drawing in a first liquid into the pumping unit via a first solvent supply line; determining one or more switching points of time for switching between different solvent supply lines, the switching points of time being determined in a way that at said switching points of time, the liquid supplied to the pumping unit is in a predefined pressure range; switching from the first solvent supply line to a second solvent supply line at one of said switching points of time; drawing in a second liquid into the pumping unit via the second solvent supply line.
摘要翻译：一种用于在液体供应系统中以可控比例计量两种或多种液体并用于供应所得混合物的方法，其中所述液体供应系统包括多个溶剂供应管线，配置阀插入在所述溶剂供应管线之间，抽吸单元，该方法包括经由第一溶剂供应管线将第一液体引入泵送单元; 确定用于在不同溶剂供应管线之间切换的一个或多个切换点，所述切换点的时间是以在所述切换时间点被供应到所述泵送单元的液体处于预定压力范围内的方式确定的; 在所述切换点之一从第一溶剂供应管线切换到第二溶剂供应管线; 通过第二溶剂供应管线将第二液体吸入泵送单元。

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