会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 2. 发明授权
    • Face feature point detection apparatus and feature point detection apparatus
    • 面部特征点检测装置和特征点检测装置
    • US07936902B2
    • 2011-05-03
    • US11667670
    • 2004-11-12
    • Koichi Kinoshita
    • Koichi Kinoshita
    • G06K9/00
    • G06K9/00281G06T7/75G06T2207/30201
    • Plural nodes are arranged at predetermined initial positions, and feature values at plural sampling points around each node are obtained as a node feature value of each corresponding node. An error estimator indicating displacement between the current position of each node and the position of corresponding feature point is obtained based on correlation information on a difference between the node feature value obtained in a state in which the plural nodes are arranged at correct positions of the corresponding feature points and the node feature value obtained in a state in which the plural nodes are arranged at wrong positions of the corresponding feature points in a learning image, correlation information on a difference between the correct position and the wrong position, and a node feature value of each node. The position of each feature point is estimated in an input image based on the error estimator and the current position of each node.
    • 多个节点被布置在预定的初始位置,并且获得每个节点周围多个采样点的特征值作为每个对应节点的节点特征值。 基于相关信息获得各个节点的当前位置与对应的特征点的位置之间的位移的误差估计器,该相关信息是在将多个节点布置在相应的位置的正确位置的状态下获得的节点特征值 特征点和在多个节点布置在学习图像中的相应特征点的错误位置的状态下获得的节点特征值,关于正确位置和错误位置之间的差异的相关信息以及节点特征值 的每个节点。 基于误差估计器和每个节点的当前位置,在输入图像中估计每个特征点的位置。
    • 4. 发明授权
    • Semiconductor integrated circuit
    • 半导体集成电路
    • US07329938B2
    • 2008-02-12
    • US10845247
    • 2004-05-14
    • Koichi Kinoshita
    • Koichi Kinoshita
    • H01L29/00
    • H01L27/0207H01L27/11807
    • A semiconductor integrated circuit includes a first cell spanning one of the p-wells and one of the n-wells adjacent to each other, and having one end on a dividing line inside the p-well and another end on a dividing line inside the n-well, and having a height determined by the one end and the another end; and a second cell, spanning another one of the p-wells and another one of the n-wells adjacent to each other, with a height covering the entire widths of the p- and n-wells measured along the column direction, the height of the second cell is double that of the first cell.
    • 一种半导体集成电路包括跨越p阱中的一个和彼此相邻的n个阱中的一个的第一单元,并且在p阱内部的分隔线上的一端和n阱内的分界线上的另一端 并且具有由一端和另一端确定的高度; 以及跨越另一个p阱和彼此相邻的n个阱中的另一个的第二单元,具有覆盖沿着列方向测量的p阱和n阱的整个宽度的高度, 第二个单元格是第一个单元格的两倍。
    • 8. 发明授权
    • Process for preparing pharmacologically acceptable salt of N-(1(S)-ethoxycarbonyl-3-phenylpropyl)-L-alanyl-amino acid
    • 制备N-(1(S) - 乙氧基羰基-3-苯基丙基)-L-丙氨酰 - 氨基酸的药理学上可接受的盐的方法
    • US06713628B2
    • 2004-03-30
    • US10295897
    • 2002-11-18
    • Yasuyoshi UedaKoichi KinoshitaTadashi MoroshimaYoshifumi YanagidaYoshihide Fuse
    • Yasuyoshi UedaKoichi KinoshitaTadashi MoroshimaYoshifumi YanagidaYoshihide Fuse
    • C07D20704
    • C07K5/0222C07K5/06026
    • There is provided a process for preparing a pharmacologically acceptable salt of N-(1(S)-ethoxycarbonyl-3-phenylpropyl)-L-alanyl-amino acid which comprises condensing an amino acid and N-(1(S)-ethoxycarbonyl-3-phenylpropyl)-L-alanine.N-carboxyanhydride under basic condition, carrying out decarboxylation under between neutral and acidic condition to obtain N-(1(S)-ethoxycarbonyl-3-phenylpropyl)-L-alanyl-amino acid, and forming a pharmacologically acceptable salt thereof, wherein the production of a by-product (3): is suppressed by carrying out in an aqueous liquid a series of operations till formation of the pharmacologically acceptable salt or till isolation of the pharmacologically acceptable salt. The present invention enables to prepare the pharmacologically acceptable salt of N-(1(S)-ethoxycarbonyl-3-phenylpropyl)-L-alanyl-amino acid having high quality, in a commercial scale with high yield and economical efficiency.
    • 提供了制备N-(1(S) - 乙氧基羰基-3-苯基丙基)-L-丙氨酰 - 氨基酸的药学上可接受的盐的方法,其包括将氨基酸和N-(1(S) - 乙氧基羰基 - 3-苯基丙基)-L-丙氨酸N-羧酸酐,在中性和酸性条件下进行脱羧,得到N-(1(S) - 乙氧基羰基-3-苯基丙基)-L-丙氨酰 - 氨基酸,和 形成其药理学上可接受的盐,其中通过在含水液体中进行一系列操作直到形成药理学上可接受的盐或直到药理学上可接受的盐的分离来抑制副产物(3)的产生。 本发明能够以高产率和经济效益以商业规模制备质量高的N-(1(S) - 乙氧基羰基-3-苯基丙基)-L-丙氨酰 - 氨基酸的药理学上可接受的盐。
    • 9. 发明授权
    • Processes for producing &bgr;-halogeno-&agr;-amino-carboxylic acids and phenylcysteine derivatives and intermediates thereof
    • 制备β-卤代-α-氨基 - 羧酸和苯基半胱氨酸衍生物的方法及其中间体
    • US06372941B1
    • 2002-04-16
    • US09582461
    • 1999-08-16
    • Koki YamashitaKenji InoueKoichi KinoshitaYasuyoshi UedaHiroshi Murao
    • Koki YamashitaKenji InoueKoichi KinoshitaYasuyoshi UedaHiroshi Murao
    • C07C22900
    • C07C227/16C07C319/14Y02P20/55C07C323/58C07C323/59C07C229/20
    • An industrially advantageous method of producing &bgr;-halogeno-&agr;-aminocarboxylic acids is provided. Methods are also provided of producing optically active N-protected-S-phenylcysteines having high optical purity and of intermediates thereof, respectively, in which the above production method is utilized. A method of producing &bgr;-halogeno-&agr;-aminocarboxylic acids or salts thereof is disclosed which comprises halogenating the hydroxyl group of a &bgr;-hydroxy-&agr;-aminocarboxylic acid (in which the basicity of the amino group in &agr;-position is not masked by the presence of a substituent on said amino group) or a salt thereof with an acid with a halogenating agent. A method of producing optically active N-protected-S-phenylcysteines represented by the general formula (3) or salts thereof is further disclosed which comprises applying the above production method to optically active serine or a salt thereof and then carrying out treatment with an amino-protecting agent and reaction with thiophenol under a basic condition.
    • 提供了产生β-卤代-α-氨基羧酸的工业上有利的方法。 还提供了分别制备具有高光学纯度的光学活性N-保护的S-苯基半胱氨酸及其中间体的方法,其中使用上述制备方法.1。制备β-卤代-α-氨基羧酸或其盐的方法 其中包括将β-羟基-α-氨基羧酸的羟基(其中在所述氨基上不存在取代基的α-位置上的氨基的碱性)或其盐与卤素化反应 具有卤化剂的酸。 进一步公开了制备由通式(3)表示的光学活性N-保护的S-苯基半胱氨酸或其盐的方法,其包括将上述制备方法应用于光学活性丝氨酸或其盐,然后用氨基 保护剂和与苯硫酚在基本条件下的反应。