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1. 发明授权

US08577474B2 Minimizing interference between charging and telemetry coils in an implantable medical device 有权
公开(公告)号：US08577474B2
公开(公告)日：2013-11-05
申请号：US12616178
申请日：2009-11-11
申请人： Md. Mizanur Rahman , Kiran Nimmagadda , Jordi Parramon , Emanuel Feldman
发明人： Md. Mizanur Rahman , Kiran Nimmagadda , Jordi Parramon , Emanuel Feldman
IPC分类号： A61N1/372 , A61N1/378
CPC分类号： A61N1/37217 , A61N1/3718 , A61N1/37211 , A61N1/37229 , A61N1/3758 , A61N1/3787
摘要： An improved implantable pulse generator (IPG) containing improved telemetry circuitry is disclosed. The IPG includes charging and telemetry coils within the IPG case, which increases their mutual inductance and potential to interfere with each other; particularly problematic is interference to the telemetry coil caused by the charging coil. To combat this, improved telemetry circuitry includes decoupling circuitry for decoupling the charging coil during periods of telemetry between the IPG and an external controller. Such decoupling circuitry can comprise use of pre-existing LSK circuitry during telemetry, or new discrete circuitry dedicated to decoupling. The decoupling circuitry is designed to prevent or at least reduce induced current flowing through the charging coil during data telemetry. The decoupling circuitry can be controlled by the microcontroller in the IPG, or can automatically decouple the charging coil at appropriate times to mitigate an induced current without instruction from the microcontroller.

2. 发明授权

US09233254B2 Selectable boost converter and charge pump for compliance voltage generation in an implantable stimulator device 有权
标题翻译：可选择的升压转换器和电荷泵，用于可植入刺激器装置中的顺应性电压产生
公开(公告)号：US09233254B2
公开(公告)日：2016-01-12
申请号：US12372501
申请日：2009-02-17
申请人： Kiran Nimmagadda , Md. Mizanur Rahman , Jordi Parramon
发明人： Kiran Nimmagadda , Md. Mizanur Rahman , Jordi Parramon
IPC分类号： A61N1/378 , H02M3/07 , H02M3/156 , H02M1/00
CPC分类号： A61N1/3782 , A61N1/37211 , A61N1/378 , H02M3/07 , H02M3/156 , H02M2001/009
摘要： Improved compliance voltage generation circuitry for a medical device is disclosed. The improved circuitry in one embodiment comprises a boost converter and a charge pump, either of which is capable of generating an appropriate compliance voltage from the voltage of the battery in the device. A telemetry enable signal indicating whether the implant's transmitter, receiver, or both, have been enabled is received. A “boost” signal from compliance voltage monitor-and-adjust logic circuitry is processed with the telemetry enable signal and its inverse to selectively enable either the charge pump or the boost converter: if the telemetry enable signal is not active, the boost converter is used to generate the compliance voltage; if the telemetry enable signal is active, the charge pump is used. Because the charge pump circuitry does not produce a magnetic field, the charge pump will not interfere with magnetically-coupled telemetry between the implant and an external controller. By contrast, the boost converter is allowed to operate during periods of no telemetry, when magnetic interference is not a concern, while obtaining the advantage of higher power efficiency.
摘要翻译：公开了用于医疗装置的改进的顺应性电压产生电路。一个实施例中的改进的电路包括升压转换器和电荷泵，其中任何一个能够从装置中的电池的电压产生适当的顺应性电压。接收到指示植入物的发射器，接收器或两者是否被使能的遥测使能信号。来自合规电压监控调节逻辑电路的“升压”信号通过遥测使能信号进行处理，其反相选择使能电荷泵或升压转换器：如果遥测使能信号无效，升压转换器用于产生合规电压; 如果遥测使能信号有效，则使用电荷泵。由于电荷泵电路不产生磁场，电荷泵不会干扰植入物和外部控制器之间的磁耦合遥测。相比之下，在没有遥测的时期，升压转换器在磁干扰不受关注的同时获得了较高功率效率的优势，允许运行。

3. 发明申请

US20110112610A1 Minimizing Interference Between Charging and Telemetry Coils in an Implantable Medical Device 有权
标题翻译：最小化植入式医疗设备中充电和遥测线圈之间的干扰
公开(公告)号：US20110112610A1
公开(公告)日：2011-05-12
申请号：US12616178
申请日：2009-11-11
申请人： Md. Mizanur Rahman , Kiran Nimmagadda , Jordi Parramon , Emanuel Feldman
发明人： Md. Mizanur Rahman , Kiran Nimmagadda , Jordi Parramon , Emanuel Feldman
IPC分类号： A61N1/08 , A61N1/375
CPC分类号： A61N1/37217 , A61N1/3718 , A61N1/37211 , A61N1/37229 , A61N1/3758 , A61N1/3787
摘要： An improved implantable pulse generator (IPG) containing improved telemetry circuitry is disclosed. The IPG includes charging and telemetry coils within the IPG case, which increases their mutual inductance and potential to interfere with each other; particularly problematic is interference to the telemetry coil caused by the charging coil. To combat this, improved telemetry circuitry includes decoupling circuitry for decoupling the charging coil during periods of telemetry between the IPG and an external controller. Such decoupling circuitry can comprise use of pre-existing LSK circuitry during telemetry, or new discrete circuitry dedicated to decoupling. The decoupling circuitry is designed to prevent or at least reduce induced current flowing through the charging coil during data telemetry. The decoupling circuitry can be controlled by the microcontroller in the IPG, or can automatically decouple the charging coil at appropriate times to mitigate an induced current without instruction from the microcontroller.
摘要翻译：公开了一种包含改进的遥测电路的改进的可植入脉冲发生器（IPG）。 IPG包括IPG案例中的充电和遥测线圈，增加了互感和相互干扰的潜力; 特别有问题的是由充电线圈引起的遥测线圈的干扰。为了解决这个问题，改进的遥测电路包括去耦电路，用于在IPG和外部控制器之间的遥测期间解耦充电线圈。这种去耦电路可以包括在遥测期间使用预先存在的LSK电路，或者专用于解耦的新的分立电路。去耦电路设计为在数据遥测期间防止或至少减少流过充电线圈的感应电流。去耦电路可以由IPG中的微控制器控制，或者可以在适当的时间自动地去耦合充电线圈，以减轻感应电流而不需要微控制器的指令。

4. 发明申请

US20100211132A1 Selectable Boost Converter and Charge Pump for Compliance Voltage Generation in an Implantable Stimulator Device 有权
标题翻译：可选择的升压转换器和电荷泵，用于在植入式刺激器装置中实现合规电压产生
公开(公告)号：US20100211132A1
公开(公告)日：2010-08-19
申请号：US12372501
申请日：2009-02-17
申请人： Kiran Nimmagadda , Md. Mizanur Rahman , Jordi Parramon
发明人： Kiran Nimmagadda , Md. Mizanur Rahman , Jordi Parramon
IPC分类号： A61N1/08
CPC分类号： A61N1/3782 , A61N1/37211 , A61N1/378 , H02M3/07 , H02M3/156 , H02M2001/009
摘要： Improved compliance voltage generation circuitry for a medical device is disclosed. The improved circuitry in one embodiment comprises a boost converter and a charge pump, either of which is capable of generating an appropriate compliance voltage from the voltage of the battery in the device. A telemetry enable signal indicating whether the implant's transmitter, receiver, or both, have been enabled is received. A “boost” signal from compliance voltage monitor-and-adjust logic circuitry is processed with the telemetry enable signal and its inverse to selectively enable either the charge pump or the boost converter: if the telemetry enable signal is not active, the boost converter is used to generate the compliance voltage; if the telemetry enable signal is active, the charge pump is used. Because the charge pump circuitry does not produce a magnetic field, the charge pump will not interfere with magnetically-coupled telemetry between the implant and an external controller. By contrast, the boost converter is allowed to operate during periods of no telemetry, when magnetic interference is not a concern, while obtaining the advantage of higher power efficiency.
摘要翻译：公开了用于医疗装置的改进的顺应性电压产生电路。一个实施例中的改进的电路包括升压转换器和电荷泵，其中任何一个能够从装置中的电池的电压产生适当的顺应性电压。接收到指示植入物的发射器，接收器或两者是否被使能的遥测使能信号。来自合规电压监控调节逻辑电路的“升压”信号通过遥测使能信号进行处理，其反相选择使能电荷泵或升压转换器：如果遥测使能信号无效，升压转换器用于产生合规电压; 如果遥测使能信号有效，则使用电荷泵。由于电荷泵电路不产生磁场，电荷泵不会干扰植入物和外部控制器之间的磁耦合遥测。相比之下，在没有遥测的时期，升压转换器在磁干扰不受关注的同时获得了较高功率效率的优势，允许运行。

5. 发明授权

US08744592B2 Efficient external charger for an implantable medical device optimized for fast charging and constrained by an implant power dissipation limit 有权
标题翻译：用于可植入医疗设备的高效外部充电器，针对快速充电而优化，并受到植入物功率限制的限制
公开(公告)号：US08744592B2
公开(公告)日：2014-06-03
申请号：US12575733
申请日：2009-10-08
申请人： Rafael Carbunaru , Jordi Parramon , Robert Ozawa , Jess Shi , Joey Chen , Md. Mizanur Rahman
发明人： Rafael Carbunaru , Jordi Parramon , Robert Ozawa , Jess Shi , Joey Chen , Md. Mizanur Rahman
IPC分类号： A61N1/00 , H02J7/00 , A61N1/378 , A61N1/372 , A61N1/36
CPC分类号： A61N1/3787 , A61N1/3605 , A61N1/37205 , A61N1/37217
摘要： An improved external charger for a battery in an implantable medical device (implant), and technique for charging the battery using such improved external charger, is disclosed. In one example, simulation data is used to model the power dissipation of the charging circuitry in the implant at varying levels of implant power. A power dissipation limit is chosen to constrain the charging circuitry from producing an inordinate amount of heat to the tissue surrounding the implant, and duty cycles are determined for the various levels of input intensities to ensure that the power limit is not exceeded. A maximum simulated average battery current determines the optimal (i.e., quickest) battery charging current, and at least an optimal value for a parameter indicative of that current, for example, the voltage across the battery charging circuitry, is determined and stored in the external charger. During charging, the actual value for that parameter is reported from the implant to the external charger, which in turn adjusts the intensity and/or duty cycle of the magnetic charging field consistent with the simulation to ensure that charging is as fast as possible, while still not exceeding the power dissipation limit.
摘要翻译：公开了用于可植入医疗装置（植入物）中的电池的改进的外部充电器以及使用这种改进的外部充电器对电池充电的技术。在一个示例中，模拟数据用于以不同的植入功率水平对植入物中的充电电路的功率耗散进行建模。选择功率耗散极限以限制充电电路对植入物周围的组织产生过量的热量，并且针对各种输入强度级别确定占空比以确保不超过功率限制。最大模拟平均电池电流确定最佳（即最快）电池充电电流，并且至少确定表示该电流的参数（例如，电池充电电路两端的电压）的最佳值，并将其存储在外部充电器。在充电期间，该参数的实际值从注入到外部充电器报告，外部充电器依次调整充电场的强度和/或占空比，与模拟一致，以确保充电尽可能快，同时仍然不超过功耗限制。

6. 发明授权

US08676318B2 Efficient external charger for charging a plurality of implantable medical devices 有权
标题翻译：用于对多个可植入医疗装置进行充电的高效外部充电器
公开(公告)号：US08676318B2
公开(公告)日：2014-03-18
申请号：US12624162
申请日：2009-11-23
申请人： Rafael Carbunaru , Jordi Parramon , Robert Ozawa , Jess Shi , Joey Chen , Md. Mizanur Rahman
发明人： Rafael Carbunaru , Jordi Parramon , Robert Ozawa , Jess Shi , Joey Chen , Md. Mizanur Rahman
IPC分类号： A61N1/08
CPC分类号： A61N1/3787 , A61N1/37223 , A61N1/37288
摘要： An improved external charger for a battery in an implantable medical device (implant), and technique for charging batteries in multiple implants using such improved external charger, is disclosed. During charging, values for a parameter measured in the implants are reported from the implants to the external charger. The external charger infers from the magnitudes of the parameters which of the implants has the highest and lowest coupling to the external charger, and so designates those implants as “hot” and “cold.” The intensity of the magnetic charging field is optimized for the cold implant consistent with the simulation to ensure that that the cold implant is charged with a maximum (fastest) battery charging current. The duty cycle of the magnetic charging field is also optimized for the hot implant consistent with the simulation to ensure that the hot implant does not exceed the power dissipation limit. As a result, charging is optimized to be fast for all of the implants, while still safe from a tissue heating perspective.
摘要翻译：公开了一种用于可植入医疗装置（植入物）中的电池的改进的外部充电器，以及使用这种改进的外部充电器为多个植入物中的电池充电的技术。在充电期间，在植入物中测量的参数的值从植入物报告给外部充电器。外部充电器从参数的大小推断出植入物具有最高和最低耦合到外部充电器的参数，因此将这些植入物称为“热”和“冷”。对于与模拟一致的冷植入物，磁充电场的强度被优化，以确保冷植入物以最大（最快）的电池充电电流充电。对于与模拟一致的热注入，磁充电场的占空比也被优化，以确保热植入物不超过功率耗散极限。因此，对于所有植入物，充电被优化为快速，同时从组织加热的角度来看仍然是安全的。

7. 发明申请

US20110121777A1 Efficient External Charger for Charging a Plurality of Implantable Medical Devices 有权
标题翻译：高效的外部充电器为多种植入式医疗设备充电
公开(公告)号：US20110121777A1
公开(公告)日：2011-05-26
申请号：US12624162
申请日：2009-11-23
申请人： Rafael Carbunaru , Jordi Parramon , Robert Ozawa , Jess Shi , Joey Chen , Md. Mizanur Rahman
发明人： Rafael Carbunaru , Jordi Parramon , Robert Ozawa , Jess Shi , Joey Chen , Md. Mizanur Rahman
IPC分类号： H02J7/00
CPC分类号： A61N1/3787 , A61N1/37223 , A61N1/37288
摘要： An improved external charger for a battery in an implantable medical device (implant), and technique for charging batteries in multiple implants using such improved external charger, is disclosed. During charging, values for a parameter measured in the implants are reported from the implants to the external charger. The external charger infers from the magnitudes of the parameters which of the implants has the highest and lowest coupling to the external charger, and so designates those implants as “hot” and “cold.” The intensity of the magnetic charging field is optimized for the cold implant consistent with the simulation to ensure that that the cold implant is charged with a maximum (fastest) battery charging current. The duty cycle of the magnetic charging field is also optimized for the hot implant consistent with the simulation to ensure that the hot implant does not exceed the power dissipation limit. As a result, charging is optimized to be fast for all of the implants, while still safe from a tissue heating perspective.
摘要翻译：公开了一种用于可植入医疗装置（植入物）中的电池的改进的外部充电器，以及使用这种改进的外部充电器为多个植入物中的电池充电的技术。在充电期间，在植入物中测量的参数的值从植入物报告给外部充电器。外部充电器从参数的大小推断出植入物中的哪一个具有与外部充电器最高和最低耦合的参数，因此将这些植入物称为“热”和“冷”。磁充电场的强度针对冷植入物与模拟一致，以确保冷植入物充电最大（最快）的电池充电电流。对于与模拟一致的热注入，磁充电场的占空比也被优化，以确保热植入物不超过功率耗散极限。因此，对于所有植入物，充电被优化为快速，同时从组织加热的角度来看仍然是安全的。

8. 发明授权

US08666504B2 Communication and charging circuitry for a single-coil implantable medical device 有权
标题翻译：用于单线圈可植入医疗设备的通信和充电电路
公开(公告)号：US08666504B2
公开(公告)日：2014-03-04
申请号：US13608490
申请日：2012-09-10
申请人： Vasily Dronov , Jordi Parramon , Robert Ozawa , Md. Mizanur Rahman , Emanuel Feldman
发明人： Vasily Dronov , Jordi Parramon , Robert Ozawa , Md. Mizanur Rahman , Emanuel Feldman
IPC分类号： A61N1/05
CPC分类号： H01F38/14 , A61N1/36 , A61N1/37223 , A61N1/3787 , H02J50/12 , H04Q9/12
摘要： Communication and charging circuitry for an implantable medical device is described having a single coil for receiving charging energy and for data telemetry. The circuitry removes from the AC side of the circuit a tuning capacitor and switch traditionally used to tune the tank circuitry to different frequencies for telemetry and charging. As such, the tank circuitry is simplified and contains no switchable components. A switch is serially connected to the storage capacitor on the DC side of the circuit. During telemetry, the switch is opened, thus disconnecting the storage capacitor from the tank circuit, and alleviating concerns that this capacitor will couple to the tank circuit and interfere with telemetry operations. During charging, the switch is closed, which allows the storage capacitor to couple to the tank circuitry through the rectifier during some portions of the tank circuitry's resonance.
摘要翻译：描述了用于可植入医疗装置的通信和充电电路，其具有用于接收充电能量和用于数据遥测的单个线圈。该电路从电路的AC侧消除了调谐电容器和传统上用于将电路调谐到不同频率的开关，用于遥测和充电。因此，容器电路被简化并且不包含可切换的部件。开关串联连接到电路直流侧的存储电容器。在遥测期间，开关打开，从而将存储电容器与储能电路断开，并减轻该电容器将耦合到储能电路并干扰遥测操作的担忧。在充电期间，开关闭合，这允许存储电容器在储罐电路的共振的某些部分期间通过整流器耦合到储能电路。

9. 发明申请

US20130103115A1 Communication and Charging Circuitry for a Single-Coil Implantable Medical Device 有权
标题翻译：单线圈可植入医疗设备的通信和充电电路
公开(公告)号：US20130103115A1
公开(公告)日：2013-04-25
申请号：US13608490
申请日：2012-09-10
申请人： Vasily Dronov , Jordi Parramon , Robert Ozawa , Md. Mizanur Rahman , Emanuel Feldman
发明人： Vasily Dronov , Jordi Parramon , Robert Ozawa , Md. Mizanur Rahman , Emanuel Feldman
IPC分类号： A61N1/08
CPC分类号： H01F38/14 , A61N1/36 , A61N1/37223 , A61N1/3787 , H02J50/12 , H04Q9/12
摘要： Communication and charging circuitry for an implantable medical device is described having a single coil for receiving charging energy and for data telemetry. The circuitry removes from the AC side of the circuit a tuning capacitor and switch traditionally used to tune the tank circuitry to different frequencies for telemetry and charging. As such, the tank circuitry is simplified and contains no switchable components. A switch is serially connected to the storage capacitor on the DC side of the circuit. During telemetry, the switch is opened, thus disconnecting the storage capacitor from the tank circuit, and alleviating concerns that this capacitor will couple to the tank circuit and interfere with telemetry operations. During charging, the switch is closed, which allows the storage capacitor to couple to the tank circuitry through the rectifier during some portions of the tank circuitry's resonance.
摘要翻译：描述了用于可植入医疗装置的通信和充电电路，其具有用于接收充电能量和用于数据遥测的单个线圈。该电路从电路的AC侧消除了调谐电容器和传统上用于将电路调谐到不同频率的开关，用于遥测和充电。因此，容器电路被简化并且不包含可切换的部件。开关串联连接到电路直流侧的存储电容器。在遥测期间，开关打开，从而将存储电容器与储能电路断开，并减轻该电容器将耦合到储能电路并干扰遥测操作的担忧。在充电期间，开关闭合，这允许存储电容器在储罐电路的共振的某些部分期间通过整流器耦合到储能电路。

10. 发明申请

US20130110203A1 Managing a Multi-function Coil in an Implantable Medical Device Using an Optical Switch 审中-公开
标题翻译：使用光开关管理植入式医疗设备中的多功能线圈
公开(公告)号：US20130110203A1
公开(公告)日：2013-05-02
申请号：US13611518
申请日：2012-09-12
申请人： Vasily Dronov , Jordi Parramon , Daniel Aghassian , Md. Mizanur Rahman , Emanuel Feldman
发明人： Vasily Dronov , Jordi Parramon , Daniel Aghassian , Md. Mizanur Rahman , Emanuel Feldman
IPC分类号： A61N1/378
CPC分类号： A61N1/3727 , A61N1/3787
摘要： Combination charging and telemetry circuit for use within an implantable medical device uses a single coil for both charging and telemetry that is controlled via the use of an opto-switch. One or more capacitors are used to tune the coil to different frequencies for receiving power from an external device and for the telemetry of information to and from an external device. The opto-switch is coupled to the resonant circuit, but because its input is electrically decoupled from its output, it easy to control.
摘要翻译：在可植入医疗设备中使用的组合充电和遥测电路使用单个线圈用于通过使用光开关来控制的充电和遥测。使用一个或多个电容器将线圈调谐到不同的频率，用于从外部设备接收功率，并用于将信号遥控到外部设备。光开关耦合到谐振电路，但由于其输入与输出电耦合，因此易于控制。

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