专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US07850152B2 Methods and devices for moisturizing hyperpolarized noble gases and associated moisturized pharmaceutical grade inhalable hyperpolarized gas products 失效
标题翻译：用于保湿超极化惰性气体和相关保湿药物级可吸入超极化气体产品的方法和装置
公开(公告)号：US07850152B2
公开(公告)日：2010-12-14
申请号：US10128048
申请日：2002-04-23
申请人： Ken Bolam , Patrick Cella , John Nouls , Brian Teixeira
发明人： Ken Bolam , Patrick Cella , John Nouls , Brian Teixeira
IPC分类号： B01F3/04
CPC分类号： A61M15/0085 , A61K49/1815 , A61M15/02 , A61M16/06 , A61M16/1045 , A61M16/109 , A61M16/142 , A61M16/16 , A61M2202/025 , A61M2202/0291
摘要： Methods and devices for moisturizing hyperpolarized noble gas and associated hyperpolarized noble gas products which are formulated for inhalation or ventilation delivery include adding moisture content to (dry) hyperpolarized gas.
摘要翻译：用于保湿超极化惰性气体和相关的超极化惰性气体产品的配方用于吸入或通风输送的方法和装置包括向（干燥）超极化气体中添加水分含量。

2. 发明申请

US20080007261A1 Methods, Systems, Circuits and Computer Program Products for Determining Polarization of a Gas 有权
标题翻译：用于确定气体极化的方法，系统，电路和计算机程序产品
公开(公告)号：US20080007261A1
公开(公告)日：2008-01-10
申请号：US11856805
申请日：2007-09-18
申请人： Zivko Djukic , Steve Kadlecek , John Nouls , Ian Nelson , Bastiaan Driehuys
发明人： Zivko Djukic , Steve Kadlecek , John Nouls , Ian Nelson , Bastiaan Driehuys
IPC分类号： G01N24/08
CPC分类号： G01R33/282 , G01R33/3628 , G01R33/3671
摘要： A system for determining polarization of a gas comprises a container that contains the polarized gas. An oscillator circuit comprises an Nuclear Magnetic Resonance (NMR) coil that is positioned adjacent to the container. A pulse generator circuit is configured to generate an electrical pulse that may be transmitted to an optical cell through the NMR coil to excite the polarized gas responsive to a control processor. A Q-reduction circuit that is independent of the pulse generator circuit is configured to reduce oscillations in the oscillator circuit from the transmitted electrical pulse responsive to the control processor. A receive circuit is responsive to an electrical signal that is induced in the oscillator circuit due to the electromagnetic excitation of the polarized gas. The control processor is configured to determine the polarization of the gas based on the output signal of the receive circuit. A polarimetry circuit for determining polarization of a gas includes an NMR coil that may be configured to excite a polarized gas and be responsive to an electromagnetic signal generated by the excited, polarized gas. The polarimetry circuit has a reproducible polarization measurement variability of less than 2% when the NMR coil is exposed to a temperature in a range of about 0° C. to about 200° C. Moreover, circuit-to-circuit polarization measurement variability may be less than about 3%.
摘要翻译：用于确定气体的极化的系统包括容纳极化气体的容器。振荡器电路包括邻近容器定位的核磁共振（NMR）线圈。脉冲发生器电路被配置为产生可以通过NMR线圈传输到光学单元的电脉冲，以响应于控制处理器激发极化气体。独立于脉冲发生器电路的Q-还原电路被配置为响应于控制处理器减少振荡器电路中的所发射的电脉冲的振荡。接收电路响应于由于极化气体的电磁激发而在振荡器电路中感应的电信号。控制处理器被配置为基于接收电路的输出信号确定气体的极化。用于确定气体极化的偏振电路包括可以被配置为激发极化气体并响应于被激发的极化气体产生的电磁信号的NMR线圈。当NMR线圈暴露于约0℃至约200℃范围内的温度时，偏振测量电路具有小于2％的可再现偏振测量可变性。此外，电路到电路偏振测量的可变性可以是小于约3％。

3. 发明授权

US07746075B2 Methods, systems, circuits and computer program products for determining polarization of a gas 有权
标题翻译：用于确定气体极化的方法，系统，电路和计算机程序产品
公开(公告)号：US07746075B2
公开(公告)日：2010-06-29
申请号：US11856805
申请日：2007-09-18
申请人： Zivko Djukic , Steve Kadlecek , John Nouls , Ian Nelson , Bastiaan Driehuys
发明人： Zivko Djukic , Steve Kadlecek , John Nouls , Ian Nelson , Bastiaan Driehuys
IPC分类号： G01V3/00
CPC分类号： G01R33/282 , G01R33/3628 , G01R33/3671
摘要： A circuit for determining a polarization of a gas. The circuit includes a polarimetry circuit having an NMR coil that is configured to excite a polarized gas and that is responsive to an electromagnetic signal generated by the excited, polarized gas. The polarimetry circuit has a reproducible polarization measurement variability of less than about 2% when the NMR coil is exposed to a temperature in a range of about 0° C. to about 200° C.
摘要翻译：用于确定气体极化的电路。电路包括具有NMR线圈的偏振电路，其被配置为激发极化气体并且响应于被激发的极化气体产生的电磁信号。当NMR线圈暴露在约0℃至约200℃的温度范围内时，该偏振测量电路具有小于约2％的可再现偏振测量可变性。

4. 发明授权

US07275413B2 Methods, systems, circuits, and computer program products for determining polarization of a gas 有权
标题翻译：用于确定气体极化的方法，系统，电路和计算机程序产品
公开(公告)号：US07275413B2
公开(公告)日：2007-10-02
申请号：US11280069
申请日：2005-11-16
申请人： Zivko Djukic , Steve Kadlecek , John Nouls , Ian Nelson , Bastiaan Driehuys
发明人： Zivko Djukic , Steve Kadlecek , John Nouls , Ian Nelson , Bastiaan Driehuys
IPC分类号： G01N24/08
CPC分类号： G01R33/282 , G01R33/3628 , G01R33/3671
摘要： A system for determining polarization of a gas comprises a container that contains the polarized gas. An oscillator circuit comprises an Nuclear Magnetic Resonance (NMR) coil that is positioned adjacent to the container. A pulse generator circuit is configured to generate an electrical pulse that may be transmitted to an optical cell through the NMR coil to excite the polarized gas responsive to a control processor. A Q-reduction circuit that is independent of the pulse generator circuit is configured to reduce oscillations in the oscillator circuit from the transmitted electrical pulse responsive to the control processor. A receive circuit is responsive to an electrical signal that is induced in the oscillator circuit due to the electromagnetic excitation of the polarized gas. The control processor is configured to determine the polarization of the gas based on the output signal of the receive circuit. A polarimetry circuit for determining polarization of a gas includes an NMR coil that may be configured to excite a polarized gas and be responsive to an electromagnetic signal generated by the excited, polarized gas. The polarimetry circuit has a reproducible polarization measurement variability of less than 2% when the NMR coil is exposed to a temperature in a range of about 0° C. to about 200° C. Moreover, circuit-to-circuit polarization measurement variability may be less than about 3%.
摘要翻译：用于确定气体的极化的系统包括容纳极化气体的容器。振荡器电路包括邻近容器定位的核磁共振（NMR）线圈。脉冲发生器电路被配置为产生可以通过NMR线圈传输到光学单元的电脉冲，以响应于控制处理器激发极化气体。独立于脉冲发生器电路的Q-还原电路被配置为响应于控制处理器减少振荡器电路中的所发射的电脉冲的振荡。接收电路响应于由于极化气体的电磁激发而在振荡器电路中感应的电信号。控制处理器被配置为基于接收电路的输出信号确定气体的极化。用于确定气体极化的偏振电路包括可以被配置为激发极化气体并响应于被激发的极化气体产生的电磁信号的NMR线圈。当NMR线圈暴露于约0℃至约200℃范围内的温度时，偏振测量电路具有小于2％的可再现偏振测量可变性。此外，电路到电路偏振测量的可变性可以是小于约3％。

5. 发明申请

US20060269614A1 Multi-cell polarizer systems for hyperpolarizing gases 审中-公开
标题翻译：用于超极化气体的多单元偏振器系统
公开(公告)号：US20060269614A1
公开(公告)日：2006-11-30
申请号：US10542293
申请日：2004-01-20
申请人： Ian Nelson , Stephen Kadlecek , John Nouls , Edward Karwacki , Kenneth Bolam , Jim Davidson
发明人： Ian Nelson , Stephen Kadlecek , John Nouls , Edward Karwacki , Kenneth Bolam , Jim Davidson
IPC分类号： H01J27/00 , A61K33/00
CPC分类号： G01R33/282 , A61K33/00 , F04B17/00 , F04B43/06 , F04B45/043 , F04B45/053 , F04B45/061
摘要： Methods, systems, assemblies, computer program products and devices produce hyperpolarized gas by: (a) providing a plurality of cells (30), each having a respective quantity of target gas held therein; (b) polarizing the target gas in and/or from the cells in a desired order to provide separate batches of polarized gas; and (c) repolarizing the previously polarized target gas held in least one of the cells when the polarization level falls below a predetermined value.
摘要翻译：方法，系统，组件，计算机程序产品和设备通过以下方式产生超极化气体：（a）提供多个单元（30），每个单元具有保存在其中的相应数量的目标气体; （b）以期望的顺序使目标气体在电池内和/或从电池偏振，以提供单独的批次的极化气体; 和（c）当偏振电平降低到预定值以下时，将至少一个电池中保留的先前极化的目标气体复极化。

6. 发明授权

US07127934B2 Methods, systems, circuits, and computer program products for determining polarization of a gas 有权
标题翻译：用于确定气体极化的方法，系统，电路和计算机程序产品
公开(公告)号：US07127934B2
公开(公告)日：2006-10-31
申请号：US10438464
申请日：2003-05-15
申请人： Zivko Djukic , Steve Kadlecek , John Nouls , Ian Nelson , Bastiaan Driehuys
发明人： Zivko Djukic , Steve Kadlecek , John Nouls , Ian Nelson , Bastiaan Driehuys
IPC分类号： G01N27/00
CPC分类号： G01R33/282 , G01R33/3628 , G01R33/3671
摘要： A system for determining polarization of a gas comprises a container that contains the polarized gas. An oscillator circuit comprises an NMR coil that is positioned adjacent to the container. A pulse generator circuit is configured to generate an electrical pulse that may be transmitted to the optical cell through the NMR coil to excite the polarized gas responsive to a control processor. A Q-reduction circuit that is independent of the pulse generator circuit is configured to reduce oscillations in the oscillator circuit from the transmitted electrical pulse responsive to the control processor. A receive circuit is responsive to an electrical signal that is induced in the oscillator circuit due to the electromagnetic excitation of the polarized gas. The control processor is configured to determine the polarization of the gas based on the output signal of the receive circuit. A polarimetry circuit for determining polarization of a gas includes an NMR coil that may be configured to excite a polarized gas and be responsive to an electromagnetic signal generated by the excited, polarized gas. The polarimetry circuit has a reproducible polarization measurement variability of less than 2% when the NMR coil is exposed to a temperature in a range of about 0° C. to about 200° C. Moreover, circuit-to-circuit polarization measurement variability may be less than about 3%.
摘要翻译：用于确定气体的极化的系统包括容纳极化气体的容器。振荡器电路包括与容器相邻定位的NMR线圈。脉冲发生器电路被配置为产生可以通过NMR线圈传输到光学单元的电脉冲，以响应于控制处理器激发极化气体。独立于脉冲发生器电路的Q-还原电路被配置为响应于控制处理器减少振荡器电路中的所发射的电脉冲的振荡。接收电路响应于由于极化气体的电磁激发而在振荡器电路中感应的电信号。控制处理器被配置为基于接收电路的输出信号确定气体的极化。用于确定气体极化的偏振电路包括可以被配置为激发极化气体并响应于被激发的极化气体产生的电磁信号的NMR线圈。当NMR线圈暴露于约0℃至约200℃范围内的温度时，偏振测量电路具有小于2％的可再现偏振测量可变性。此外，电路到电路偏振测量的可变性可以是小于约3％。

7. 发明申请

US20060097724A1 Methods, systems, circuits, and computer program products for determining polarization of a gas 有权
标题翻译：用于确定气体极化的方法，系统，电路和计算机程序产品
公开(公告)号：US20060097724A1
公开(公告)日：2006-05-11
申请号：US11280069
申请日：2005-11-16
申请人： Zivko Djukic , Steve Kadlecek , John Nouls , Ian Nelson , Bastiaan Driehuys
发明人： Zivko Djukic , Steve Kadlecek , John Nouls , Ian Nelson , Bastiaan Driehuys
IPC分类号： G01N24/08
CPC分类号： G01R33/282 , G01R33/3628 , G01R33/3671
摘要： A system for determining polarization of a gas comprises a container that contains the polarized gas. An oscillator circuit comprises an NMR coil that is positioned adjacent to the container. A pulse generator circuit is configured to generate an electrical pulse that may be transmitted to the optical cell through the NMR coil to excite the polarized gas responsive to a control processor. A Q-reduction circuit that is independent of the pulse generator circuit is configured to reduce oscillations in the oscillator circuit from the transmitted electrical pulse responsive to the control processor. A receive circuit is responsive to an electrical signal that is induced in the oscillator circuit due to the electromagnetic excitation of the polarized gas. The control processor is configured to determine the polarization of the gas based on the output signal of the receive circuit. A polarimetry circuit for determining polarization of a gas includes an NMR coil that may be configured to excite a polarized gas and be responsive to an electromagnetic signal generated by the excited, polarized gas. The polarimetry circuit has a reproducible polarization measurement variability of less than 2% when the NMR coil is exposed to a temperature in a range of about 0° C. to about 200° C. Moreover, circuit-to-circuit polarization measurement variability may be less than about 3%
摘要翻译：用于确定气体的极化的系统包括容纳极化气体的容器。振荡器电路包括与容器相邻定位的NMR线圈。脉冲发生器电路被配置为产生可以通过NMR线圈传输到光学单元的电脉冲，以响应于控制处理器激发极化气体。独立于脉冲发生器电路的Q-还原电路被配置为响应于控制处理器减少振荡器电路中的所发射的电脉冲的振荡。接收电路响应于由于极化气体的电磁激发而在振荡器电路中感应的电信号。控制处理器被配置为基于接收电路的输出信号确定气体的极化。用于确定气体极化的偏振电路包括可以被配置为激发极化气体并响应于被激发的极化气体产生的电磁信号的NMR线圈。当NMR线圈暴露于约0℃至约200℃范围内的温度时，偏振测量电路具有小于2％的可再现偏振测量可变性。此外，电路到电路偏振测量的可变性可以是小于3％

8. 发明授权

US06523356B2 Meted hyperpolarized noble gas dispensing methods and associated devices 失效
公开(公告)号：US06523356B2
公开(公告)日：2003-02-25
申请号：US09949394
申请日：2001-09-07
申请人： Kenton C. Hasson , Paul L. Bogorad , David L. Zollinger , Geri T. K. Zollinger , John Nouls
发明人： Kenton C. Hasson , Paul L. Bogorad , David L. Zollinger , Geri T. K. Zollinger , John Nouls
IPC分类号： F17C1302
CPC分类号： A61K49/1815
摘要： Methods of dispensing meted quantities of hyperpolarized gas to form a hyperpolarized gas mixture include pre-filling a gas syringe with a quantity of non-polarized gas, then introducing the hyperpolarized gas therein while the non-polarized gas is held therein, and expelling both the hyperpolarized gas and non-polarized gas from the syringe. Methods of inhibiting the presence of oxygen in gas flow paths and extraction systems are also described.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式