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    • 5. 发明授权
    • Dry analysis element for quantitative analysis of analyte contained in
whole blood
    • 用于定量分析全血中所含分析物的干分析元件
    • US5788942A
    • 1998-08-04
    • US634523
    • 1996-04-18
    • Toru KitaniTakao Akagi
    • Toru KitaniTakao Akagi
    • G01N33/52G01N31/22
    • G01N33/525Y10S435/805
    • A dry analysis element for the quantitative analysis of an analyte contained in whole blood comprises a layer exhibiting volume filtration function and a detection layer. The layer exhibiting volume filtration function is made of a cloth selected from microfibrous cloths each having an average fiber diameter of from 0.1 to 10 .mu.m or a napped cloth having an average of from 1 to 30 .mu.m. In a first preferred embodiment, the layer exhibiting volume filtration function is composed of a non-woven cloth having a density of from 0.01 to 0.2 g/cm.sup.3 and made of fibers each having an average fiber diameter of from 0.2 to 10 .mu.m. In a second preferred embodiment, the layer exhibiting volume filtration function is composed of a napped cloth having a fiber density per cm.sup.2 of from 7.0.times.10.sup.3 to 8.2.times.10.sup.6, each of the napped fibers having an average diameter of from 1 to 30 microns and an average nap length of 0.5 to 5.0 mm. In a third preferred embodiment, the layer exhibiting volume filtration function is composed of a cloth having a porosity of from 45 to 70% and made of micro filaments each having an average filament diameter of from 0.1 to 7 .mu.m.
    • 用于对全血中包含的分析物进行定量分析的干燥分析元件包括显示体积过滤功能的层和检测层。 显示体积过滤功能的层由选自平均纤维直径为0.1至10μm的微纤维布或平均为1至30μm的起绒织物的布制成。 在第一优选实施方案中,显示体积过滤功能的层由密度为0.01至0.2g / cm 3的无纺布组成,并由平均纤维直径为0.2至10μm的纤维制成。 在第二优选实施方案中,显示体积过滤功能的层由每平方厘米纤维密度为7.0×10 3至8.2×10 6 6的绒毛布组成,每个起绒纤维的平均直径为1至30微米,平均直径为1至30微米 绒毛长度为0.5〜5.0mm。 在第三优选实施方案中,显示体积过滤功能的层由具有45至70%的孔隙率的织物组成,并由平均长丝直径为0.1-7μm的微丝制成。