会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 6. 发明授权
    • Information acquiring apparatus and information acquiring method for acquiring mass-related information
    • 信息获取装置和用于获取大量相关信息的信息获取方法
    • US08704194B2
    • 2014-04-22
    • US13083510
    • 2011-04-08
    • Manabu KomatsuHiroyuki Hashimoto
    • Manabu KomatsuHiroyuki Hashimoto
    • H01J49/14H01J49/10
    • H01J49/06H01J49/0463
    • Target molecules in a sample can be detected at an improved sensitivity by means of a mass spectrometer. A sample with or without a matrix is placed on a substrate and irradiated with a converged and pulsed primary beam selected from an ion beam, a neutral particle beam or a laser beam. Secondary ions and neutral molecules are emitted along with protons from the irradiated point of the sample as an electric field is applied between the substrate and an extraction electrode disposed above the substrate. A proton-control electrode is arranged in axial symmetry with the trajectory of the primary beam. A voltage is applied thereto so that the generated electric field decelerates the flying protons to raise their adhering efficiency to the flying neutral molecules.
    • 可以通过质谱仪以更高的灵敏度检测样品中的靶分子。 将具有或不具有矩阵的样品放置在基底上并用从离子束,中性粒子束或激光束中选择的会聚且脉冲的一次束照射。 随着电场施加在基板和设置在基板之上的引出电极之间,二次离子和中性分子与质子的辐射点一起被发射出来。 质子控制电极与主光束的轨迹轴对称。 施加电压使得所产生的电场使飞行质子减速,以提高它们对飞行中性分子的附着效率。
    • 8. 发明授权
    • Information acquisition method
    • 信息采集方法
    • US08415615B2
    • 2013-04-09
    • US13351675
    • 2012-01-17
    • Shuya SatohHiroyuki Hashimoto
    • Shuya SatohHiroyuki Hashimoto
    • H01J49/26
    • H01J49/142Y10T436/24Y10T436/25Y10T436/25875
    • Provided is a method that achieves both of soft ionization and high ionization efficiency of a substance to be analyzed at each measurement site without impairing a two-dimensional distribution state of the substance to be analyzed in desorption ionization mass spectrometry of a substance to be measured. By applying, to a substance to be analyzed, an ionization assisting reagent including an organic acid including a functional group represented by —(CF2)COOH and having a boiling point of 150° C. or more, and a polyhydric alcohol having a melting point of 20° C. or less and a boiling point of 150° C. or more at normal pressure, the organic acid, which is a component of the ionization assisting reagent, effectively donates a proton to the substance to be analyzed, thereby improving ionization efficiency, and the polyhydric alcohol, which is a component of the ionization assisting reagent, inhibits fragmentation.
    • 本发明提供了一种能够在每个测量部位实现待分析物质的软电离和高电离效率的方法,而不会在待测物质的解吸电离质谱中损害待分析物质的二维分布状态。 通过将被分析物质应用于包含由 - (CF 2)COOH表示的官能团和沸点为150℃以上的有机酸的电离助剂和具有150℃以上的沸点的多元醇 在常压下为20℃以下,沸点为150℃以上,作为电离辅助剂的成分的有机酸能够有效地向待分析物质提供质子,从而提高离子化 作为电离助剂的成分的多元醇抑制分解。
    • 10. 发明授权
    • Method for obtaining information and device therefor
    • 获取信息的方法及其设备
    • US07851749B2
    • 2010-12-14
    • US12017584
    • 2008-01-22
    • Manabu KomatsuHiroyuki HashimotoYohei MurayamaKazuhiro Ban
    • Manabu KomatsuHiroyuki HashimotoYohei MurayamaKazuhiro Ban
    • H01J49/00
    • H01J49/142
    • A method for obtaining information on a mass of an object by time-of-flight mass spectrometry. This method includes placing colloidal metal particles for promoting ionization of the object inside the object at a depth ranging from 0.1 nm to 100 nm in opposition to a primary beam for the ionization; irradiating the object with the primary beam selected from the group of ions, neutral particles, and electrons, which can be focused, pulsed, and are capable of scanning, and laser beams, which can be focused, pulsed, and are capable of scanning to ionize a constituent of the object and to allow the ionized constituent to fly out of the object; and obtaining information on the mass of the flying constituent of the object by time-of-flight mass spectrometry.
    • 一种通过飞行时间质谱法获得物体质量信息的方法。 该方法包括将胶体金属颗粒放置在与离子化的主光束相反的0.1nm至100nm范围内的物体内部物体的离子化; 用可以被聚焦,脉冲和能够扫描的离子,中性粒子和电子组中选择的主要束照射物体,以及可以被聚焦,脉冲且能够扫描的激光束 电离物体的成分并使离子化成分从物体飞出; 并通过飞行时间质谱法获得关于物体飞行成分质量的信息。