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    • 1. 发明授权
    • Examination method of buffer capacity of saliva and examination instrument of buffer capacity of saliva
    • 唾液缓冲能力检查方法和唾液缓冲能力检查仪器
    • US06762058B2
    • 2004-07-13
    • US10131190
    • 2002-04-25
    • Kazuhiro TakagiJunichi OkadaYoshiko Watanabe
    • Kazuhiro TakagiJunichi OkadaYoshiko Watanabe
    • G01N3116
    • G01N33/52G01N33/84
    • To provide an examination method of buffer capacity of saliva and an examination instrument of buffer capacity of saliva, by which the buffer capacity of saliva of a subject can be examined simply without being influenced by an amount of saliva and preciously without being influenced by the subjectivity of an examiner, an end portion of an absorptive material in a predetermined shape, containing a pH indicator at least having one or more color transition range of pH 4.0 to 7.0 and an acid, is dipped in saliva to allow the saliva to penetrate into the absorptive material, and a buffer capacity of the saliva is examined from a distance where a color to be exhibited by the pH indicator has changed by the penetrated saliva from a predetermined place of the absorptive material and a distance where the saliva has penetrated from a predetermined place of the absorptive material.
    • 提供唾液缓冲能力的检查方法和唾液缓冲能力的检查仪器,通过该检查方法可以简单地检查受试者的唾液的缓冲能力,而不受唾液和珍贵的影响,而不受主观性的影响 的检查者,将含有至少具有一个或多个pH 4.0至7.0的颜色转变范围的pH指示剂和酸的预定形状的吸收材料的端部浸入唾液中以允许唾液渗透入 从所述吸收材料的预定位置的渗透的唾液和从预定的位置渗透的距离从pH指示剂显示的颜色变化的距离检查唾液的缓冲能力, 吸收材料的地方。
    • 2. 发明授权
    • Examination method of buffer capacity of saliva and examination instrument of buffer capacity of saliva
    • 唾液缓冲能力检查方法和唾液缓冲能力检查仪器
    • US07160731B2
    • 2007-01-09
    • US10241645
    • 2002-09-12
    • Kazuhiro TakagiJunichi Okada
    • Kazuhiro TakagiJunichi Okada
    • G01N31/16
    • G01N33/84
    • To provide a simple examination method of buffer capacity of saliva without influence by examiner's subjectivity and an examination instrument to carry out suitably the examination method, an examination instrument, in which two to ten kinds of chemical liquids each containing a pH indicator having a transition interval within a pH range of 3.0 to 7.0 and capable of easily discriminating its indicated color at two or more stages and an acid in an amount so as to exhibit a different pH value within a pH range of 1.5 or more but lower than 3.0 when water in the same amount as that of saliva to be examined is added at a temperature of 25° C. and a humidity of 50% are each immersed in a water-absorptive material, or are in a liquid or gel state and are accommodated within a constant-volume container, is prepared; saliva of a subject in a volume to be examined is added to each of the chemical liquids; after lapsing a predetermined time, the color of each chemical liquid is measured as a readily discriminable indicated color; and the buffer capacity of saliva is determined by overall evaluation from the readily discriminable indicated color as exhibited by the chemical liquid.
    • 为了提供唾液的缓冲能力的检查方法,不受检查者的主观性的影响,检查仪器适当地进行检查方法,检查仪器,其中两至十种各自含有具有过渡间隔的pH指示剂的化学液体 在3.0至7.0的pH范围内,并且能够容易地在两个或多个阶段区分其指示的颜色,并且酸的量可以在1.5以上且低于3.0的pH范围内显示不同的pH值 在25℃的温度和50%的湿度下加入与待检查的唾液相同的量浸渍在吸水材料中,或者处于液体或凝胶状态,并且容纳在恒定的 体积容器,准备; 将待检体积的受检者的唾液加入到每种化学液体中; 在经过预定时间之后,每个化学液体的颜色被测量为容易识别的指示颜色; 唾液的缓冲能力由化学液体显示的容易辨别的指示颜色的总体评价来确定。
    • 3. 发明授权
    • Pretreatment instrument of saliva and pretreatment method of saliva
    • 唾液预处理仪和唾液预处理方法
    • US07160689B2
    • 2007-01-09
    • US10163614
    • 2002-06-07
    • Yuko MatsumotoYumiko KobayashiJunichi Okada
    • Yuko MatsumotoYumiko KobayashiJunichi Okada
    • G01N33/53
    • G01N1/10A61B10/0051B01L3/5029B01L3/505G01N2001/028G01N2333/315
    • In a pretreatment instrument and a pretreatment method of saliva, used for identification and quantitation of Streptococcus mutans in saliva by the immunochromatographic method utilizing an antigen-antibody reaction, the instrument includes a swab and a mixing container for saliva and a treatment liquid, the swab having a stick and a soft synthetic resin-made sponge capable of absorbing a predetermined amount or more of saliva, and the mixing container being made of a transparent or translucent soft synthetic resin and comprising a bag-like portion formed integrally with and continuously to a constricted portion as the end of a tapering introduction portion having an opening thoroughly larger than the sponge, wherein the constricted portion and the bag-like portion have elasticity such that the sponge can be squashed by a finger pressure in a state that the sponge is inserted therein; the constricted portion has a width such that a pressure can be applied by fingers and has a shape such that when the sponge is taken out in a squashed state by the finger pressure, a minimum amount necessary for the pretreatment or more of the saliva can be squeezed out.
    • 在使用抗原 - 抗体反应的免疫色谱法在唾液的预处理仪器和预处理方法中,用于鉴别和定量唾液中的变形链球菌,仪器包括用于唾液和处理液的拭子和混合容器,拭子 具有能够吸收规定量以上的唾液的棒状物和软质合成树脂制海棉,所述混合容器由透明或半透明的软质合成树脂制成,并且包括一体形成的袋状部分, 收缩部分作为具有比海绵充分大的开口的锥形引入部分的端部,其中收缩部分和袋状部分具有弹性,使得海绵可以在海绵被插入的状态下被手指压力挤压 其中 收缩部分具有能够通过手指施加压力的宽度,并且具有这样的形状,使得当通过手指压力以压扁状态取出海绵时,预处理所需的最小量或更多的唾液可以是 挤出。
    • 5. 发明授权
    • Pre-treatment kit for saliva and pre-treatment method for saliva using the same
    • 用于唾液的预处理试剂盒和使用其的唾液预处理方法
    • US06897037B2
    • 2005-05-24
    • US10132474
    • 2002-04-26
    • Junichi OkadaYumiko Kobayashi
    • Junichi OkadaYumiko Kobayashi
    • G01N31/22G01N33/48G01N33/50G01N33/53G01N33/543G01N33/569C12Q1/04C12N1/00
    • G01N33/56944Y10S435/885Y10S435/975
    • To provide a pre-treatment kit for saliva and a pre-treatment method for saliva for identification and quantitation of mutans streptococci in human saliva by the immunochromatographic method, which can eliminate mucin in saliva and prevent mutans streptococci from chaining and aggregation in a simple method, the pre-treatment kit is constructed of (A) an aqueous solution containing sodium hydroxide, (B) a tris(hydroxymethyl)aminomethane buffer solution containing tartaric acid and/or citric acid, and (C) a nonionic surfactant and/or an amphoteric surfactant, wherein the component (C) is previously mixed with or prepared separately from the component (A) and/or the component (B), and further (D) a pH indicator having a color transition range of pH 5 to 9 is previously mixed with or prepared separately from the component (A) or the component (A) having the component (C) previously mixed therewith, and/or the component (B) or the component (B) having the component (C) previously mixed therewith. According the pre-treatment method, the respective components of the pre-treatment kit is added dropwise into and mixed with saliva in an arbitrary order.
    • 提供唾液预处理试剂盒和唾液预处理方法,用于通过免疫色谱法鉴定和定量人唾液中变形链球菌,可以消除唾液中的粘蛋白,并以简单的方法预防变形链球菌的链接和聚集 ,所述预处理试剂盒由(A)含有氢氧化钠的水溶液,(B)含有酒石酸和/或柠檬酸的三(羟甲基)氨基甲烷缓冲溶液和(C)非离子表面活性剂和/或 两性表面活性剂,其中组分(C)预先与组分(A)和/或组分(B)混合或制备,进一步(D)具有pH5至9的颜色过渡范围的pH指示剂为 预先与预先混合有组分(C)的组分(A)或组分(A)混合或制备,和/或组分(B)或组分(B)预先混合的组分(B)或组分 的 rewith。 根据预处理方法,将预处理试剂盒的各成分按任意顺序逐滴加入唾液中并与其混合。
    • 7. 发明授权
    • Denture base lining material
    • 义齿底衬材料
    • US5436283A
    • 1995-07-25
    • US210943
    • 1994-03-21
    • Junichi OkadaYukari Nasu
    • Junichi OkadaYukari Nasu
    • A61C13/097A61C13/07A61C13/16A61K6/00A61K6/083C08K5/12C08L33/10
    • A61K6/083
    • A denture base lining material to be used upon mixing a liquid component and a powder component is disclosed, characterized in that the liquid component comprises a phthalic ester-based plasticizer and containing from 5 to 15% by weight of ethyl alcohol and from 5 to 20% by weight of a liquid paraffin or squalane alone or a mixed solution thereof, and the powder component comprises a powder comprising any one of the following powders (a), (b), or (c), or a mixture of two or more thereof: (a) an ethyl methacrylate polymer powder containing from 1 to 5% by weight of a phthalic ester-based plasticizer; (b) a copolymer powder represented by the following formula: ##STR1## wherein n/(m+n) is from 0.15 to 0.55, and containing from 0.5 to 2% by weight of a phthalic ester-based plasticizer; and (c) a mixed powder comprising a polyethyl methacrylate powder having a copolymer powder represented by the following formula mixed therewith: ##STR2## wherein n/(m+n) is from 0.45 to 0.76. The denture base lining material according to the present invention is low in the rate of change in elastic strain, is less found in the sticky feeling, and can be readily peeled apart from the denture after the use.
    • 公开了一种在混合液体组分和粉末组分时使用的义齿底衬材料,其特征在于液体组分包含邻苯二甲酸酯类增塑剂,含有5至15重量%的乙醇和5至20重量份 单独的液体石蜡或角鲨烷或其混合溶液的重量百分数,粉末组分包括包含以下粉末(a),(b)或(c)中的任一种的粉末,或两种或更多种 (a)含有1〜5重量%邻苯二甲酸酯系增塑剂的甲基丙烯酸乙酯聚合物粉末; (b)由下式表示的共聚物粉末:其中n /(m + n)为0.15〜0.55,含有0.5〜2重量%的邻苯二甲酸酯类增塑剂; 和(c)包含具有由下式混合的共聚物粉末的聚甲基丙烯酸甲酯粉末的混合粉末:其中n /(m + n)为0.45至0.76。 根据本发明的义齿底衬材料的弹性变形率变低,在粘着感上较少发现,并且在使用后可以容易地从假牙剥离。
    • 9. 发明授权
    • Method for measuring carbon concentration in polycrystalline silicon
    • 多晶硅碳浓度测定方法
    • US08963070B2
    • 2015-02-24
    • US14110013
    • 2012-04-03
    • Junichi OkadaKouichi KobayashiFumitaka Kume
    • Junichi OkadaKouichi KobayashiFumitaka Kume
    • G01D18/00G12B13/00G01J3/42G01N21/3563G01N21/27
    • G01J3/42G01N21/274G01N21/3563
    • The present invention provides a method for making it possible to easily and simply measure approximate concentration of substitutional carbon impurities in a desired position in a polycrystalline silicon rod. A polycrystalline silicon plate is sliced out from a polycrystalline silicon rod and both surfaces of the polycrystalline silicon plate are mirror-polished to reduce the polycrystalline silicon plate to thickness of 2.12±0.01 mm. A calibration curve is created according to an infrared absorption spectroscopy and on the basis of a standard measurement method using a single crystal silicon standard sample having known substitutional carbon concentration and thickness of 2.00±0.01 mm, an infrared absorption spectrum in a frequency domain including an absorption zone peak of substitutional carbon of the polycrystalline silicon plate after the mirror polishing is calculated under conditions same as conditions during the calibration curve creation, and substitutional carbon concentration is calculated without performing thickness correction.
    • 本发明提供了一种使得可以容易且简单地测量多晶硅棒中期望位置中的取代碳杂质的近似浓度的方法。 将多晶硅板从多晶硅棒切出,并将多晶硅板的两个表面进行镜面抛光以将多晶硅板的厚度减小到2.12±0.01mm。 根据红外吸收光谱法和基于使用具有已知的取代碳浓度和厚度为2.00±0.01mm的单晶硅标准样品的标准测量方法产生校准曲线,在频域中的红外吸收光谱包括 在与校准曲线生成期间的条件相同的条件下计算镜面抛光后的多晶硅板的取代碳的吸收峰的峰值,并且计算替代碳浓度而不进行厚度校正。